[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"acl-tear\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:acl-tear":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,10,0,[8,43,75,98,124,147,169,196,216,243],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":4,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":42},"100425869","the-pediatric-all-evaluation-and-trial-100425869",false,"NCT04825587","The Pediatric ALL Evaluation and Trial","The Pediatric ALL Evaluation and Trial: A Randomized, Controlled Trial","PALLET","Inclusion Criteria:\n\n* Age 18 and under\n* Surgery within 6 months of injury\n* Undergoing primary ACL reconstruction without previous injury or surgery\n* Quadriceps tendon autograft ACL reconstruction\n* Closing or closed physes\n\nExclusion Criteria:\n\n* Over 18 years old\n* Previous ipsilateral knee injury or surgery\n* Neuromuscular or developmental disorders affecting knee anatomy, cognition, or neuromuscular control\n* Other concomitant ligament reconstruction aside from the ALL (i.e., MCL, PCL, PLC)\n* Revision ACL reconstruction\n* ACL reconstruction with graft other than quadriceps tendon\n* IT band (modified MacIntosh) ACL reconstruction\n* A cartilage lesion requiring anything more than debridement\n* Open physes requiring both femoral and tibial physeal-sparing technique",true,"ALL","18 Years",{"count":21,"type":22},240,"ESTIMATED","INTERVENTIONAL",[25],"NA","The overall aim of this multicenter RCT is to determine whether concomitant ALL reconstruction in children undergoing and ACL reconstruction will longitudinally result in a lower rate of graft failure than ACL reconstruction alone.",[28,29],"ACL Injury","ACL Tear","RECRUITING","2026-05-27",{"date":33,"type":34},"2026-05-29","ACTUAL",{"date":36,"type":34},"2021-04-28",{"date":38,"type":22},"2030-04-01",{"name":40,"class":41},"Ann & Robert H Lurie Children's Hospital of Chicago","OTHER",1,{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":49,"eligibilityCriteria":50,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":51,"enrollmentInfo":52,"targetDuration":4,"studyType":54,"phases":4,"briefSummary":55,"conditions":56,"keywords":59,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":42},"100534200","do-patients-with-acl-tears-demonstrate-weakness-of-the-soleus-muscle-100534200","NCT06235736","Do Patients With ACL Tears Demonstrate Weakness of the Soleus Muscle?","Do Patients With Anterior Cruciate Ligament (ACL) Tears Demonstrate Weakness of the Soleus Muscle?","ACL","Inclusion Criteria:\n\nACL tear participants:\n\n* MRI-confirmed ACL tear.\n* Participant is willing and able to give informed consent in writing for participation in the study.\n* Male or Female, aged 18 years to 55 years of age.\n* No contraindications to strength testing (see exclusion criteria).\n\nNormative values from healthy individuals:\n\n* No current or previous history of significant lower limb injury, or a history of previous minor injury that is symptomatic at the time of recruitment.\n* No previous lower limb surgery.\n* No course of medication, whether prescribed or over the counter, other than vitamins and mineral supplements or, for females, oral contraceptives.\n\nExclusion Criteria:\n\n* History of chronic musculoskeletal disease or disorder in either leg that may put the participants at risk because of participation in the study including non-united fractures, epilepsy, cardiac insufficiency, severe peripheral vascular disease, aneurysms, anticoagulant therapy, recent (\\<3 months) radiotherapy or chemotherapy, long term steroid use (\\>3 months), pregnancy, neurological disorders (e.g., Parkinson's disease), skin conditions at point of force testing, severe osteoporosis, malignancy, rheumatoid arthritis.\n\n  * Conditions or symptoms that may influence the result of the study, or the participant's ability to participate in the study including pain, limited range of motion, knee effusion, or anaemia.","55 Years",{"count":53,"type":22},55,"OBSERVATIONAL","The goal of this prospective, cross-sectional study is to test the strength of the soleus muscle in participants who have a ACL tear confirmed by MRI. Previous studies have shown that the soleus muscle, which one of the muscles situated in the calf, decreases mechanical loading on the ACL. Therefore, we aim to test soleus muscle strength using a seated plantar flexor test.\n\nThe main questions we aim to answer are:\n\n* Do patients with ACL tears demonstrate inter-limb soleus strength asymmetry (\\>10%)\n* Do patients with ACL tears have soleus muscle weakness compared with uninjured (normative) participants?\n* Do changes in soleus strength values correlate with patient reported outcomes and stability, as measured by the IKDC questionnaire?\n\nTo achieve this the VALD force frame will be used as the testing device for plantar flexor strength testing. This device records the force generated by the movement. This will be repeated three times on each leg as part of the testing procedure. Furthermore, as part of the testing procedure participants will be required to fill out an IKDC form to assess their knee stability. Interrater reliability of the force frame will be investigated.\n\nFurther data from participants without ACL tears will be used to compare results. Thus allowing us to see if people with ACL tears have a weakness in the soleus muscle.",[29,57,58],"ACL-injury","ACL - Anterior Cruciate Ligament Rupture",[60,49,61,62,63,64,65],"Acute cruciate ligament","soleus muscle","physiotherapy","orthopaedics","trauma","rehabilitation","2026-04-30",{"date":68,"type":34},"2026-05-06",{"date":70,"type":34},"2024-01-17",{"date":72,"type":22},"2027-12-31",{"name":74,"class":41},"University of Liverpool",{"id":76,"slug":77,"hasResults":11,"nctId":78,"briefTitle":79,"officialTitle":80,"acronym":49,"eligibilityCriteria":81,"healthyVolunteers":11,"sex":18,"minAge":82,"maxAge":83,"enrollmentInfo":84,"targetDuration":4,"studyType":23,"phases":86,"briefSummary":87,"conditions":88,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":42},"100594138","quadriceps-strengthening-acl-reconstruction-100594138","NCT07015541","Quadriceps Strengthening ACL Reconstruction","Effects of Quadriceps Focused Interventions in Adolescent With ACL Reconstruction","Inclusion Criteria:\n\n* no history of knee injury\u002Fsurgery of the contralateral limb\n\nExclusion Criteria:\n\n* (1) bilateral knee injuries\n* (2) prior knee ligament injury and\u002For surgery\n* (3) multiple ligament injuries and\u002For ruptures\n* (4) conditions in which NMES and BFR are contraindicated","13 Years","17 Years",{"count":85,"type":22},40,[25],"The purpose of this study is to investigate the effects of quadriceps focused interventions on knee function and biomechanics in adolescent patients with anterior cruciate ligament reconstruction (ACLR)",[29],"2026-04-21",{"date":91,"type":34},"2026-04-22",{"date":93,"type":22},"2026-05",{"date":95,"type":22},"2027-11",{"name":97,"class":41},"Stanford University",{"id":99,"slug":100,"hasResults":11,"nctId":101,"briefTitle":102,"officialTitle":102,"acronym":103,"eligibilityCriteria":104,"healthyVolunteers":11,"sex":18,"minAge":19,"maxAge":105,"enrollmentInfo":106,"targetDuration":4,"studyType":54,"phases":4,"briefSummary":108,"conditions":109,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":115,"lastUpdatePostDateStruct":116,"startDateStruct":118,"completionDateStruct":120,"leadSponsor":122,"locationsCount":42},"100403652","multi-vendor-multi-site-novel-accelerated-mri-relaxometry-100403652","NCT04536103","Multi-Vendor Multi-Site Novel Accelerated MRI Relaxometry","MVMS_MRI","Inclusion Criteria:\n\nGroup 1\n\n1\\. Age \\> 18\n\nGroup 2\n\n1\\. Age 18-50\n\nGroup 3\n\n1. Age 18-50\n2. Sustain an acute full ACL tear in one knee; the contralateral knee uninjured\n3. Undergo ACL reconstructions and standard rehabilitation\n\nGroup 4\n\n1\\. Age 18-50\n\nExclusion Criteria:\n\nGroup 1\n\n1. Contraindication to MRI such as severe claustrophobia and implanted devices such as neurostimulators, pacemakers, aneurysm clips etc.\n2. Pregnancy.\n\nGroup 2\n\n1. Contraindication to MRI such as severe claustrophobia and implanted devices such as neurostimulators, pacemakers, aneurysm clips etc.\n2. Pregnancy.\n3. History of osteoarthritis and inflammatory arthritis\n4. Previous injury and\u002For surgery on either knee\n\nGroup 3\n\n1. Contraindication to MRI such as severe claustrophobia and implanted devices such as neurostimulators, pacemakers, aneurysm clips etc.\n2. Pregnancy.\n3. Inability to undergo standard pre- and post-injury\u002Foperative rehabilitation\n\nGroup 4\n\n1. Contraindication to MRI such as severe claustrophobia and implanted devices such as neurostimulators, pacemakers, aneurysm clips etc.\n2. Pregnancy.\n3. History of osteoarthritis and inflammatory arthritis\n4. Previous injury and\u002For surgery on either knee","50 Years",{"count":107,"type":22},88,"Currently the diagnosis of OA is based on radiographs and clinical findings, which is limited to detecting late-stage disease. There is a pressing, unmet clinical need for robust assessment of early changes in cartilage health. Towards this goal, extensive efforts are ongoing to develop quantitative MRI for cartilage matrix analysis. MR T1ρ and T2 relaxation times have shown to be promising imaging biomarkers for early cartilage degeneration and prediction of disease progression. However, many challenges remain to clinically applying these techniques, including lack of standardized acquisition and quantification methods, and long acquisition times. The study aims to develop novel, fast and reproducible MR T1ρ and T2 relaxation time imaging methods on MR systems from multiple vendors and establish a platform for standardization and cross validation of these measures as a tool for clinical trials using such techniques. Following method validation, patients at risk for osteoarthritis will be tested.",[110,111,112,113,29,114],"Bone Diseases, Infectious","Musculoskeletal Diseases","Joint Diseases","Osteoarthritis","Cartilage Degeneration","2026-02-24",{"date":117,"type":34},"2026-02-27",{"date":119,"type":34},"2022-04-01",{"date":121,"type":22},"2026-12-28",{"name":123,"class":41},"Xiaojuan Li",{"id":125,"slug":126,"hasResults":11,"nctId":127,"briefTitle":128,"officialTitle":129,"acronym":4,"eligibilityCriteria":130,"healthyVolunteers":17,"sex":18,"minAge":131,"maxAge":4,"enrollmentInfo":132,"targetDuration":4,"studyType":23,"phases":134,"briefSummary":135,"conditions":136,"keywords":4,"overallStatus":137,"whyStopped":4,"lastUpdateSubmitDate":138,"lastUpdatePostDateStruct":139,"startDateStruct":141,"completionDateStruct":143,"leadSponsor":145,"locationsCount":42},"100480146","anterior-cruciate-ligament-acl-reconstruction-with-bone-tendon-bone-autograft-with-versus-without-internal-bracing-100480146","NCT05532189","Anterior Cruciate Ligament (ACL) Reconstruction With Bone Tendon Bone Autograft With Versus Without Internal Bracing","ACL Reconstruction With Bone Tendon Bone (BTB) Autograft With Versus Without Internal Brace - Clinical and Radiographic Outcomes","Inclusion Criteria:\n\n* patients 12 and older\n* patients seen by the Columbia University Sports Medicine Service\n* patients diagnosed with a first time ACL injury by clinical exam and MRI\n\nExclusion Criteria:\n\n* previous knee surgery\n* concurrent knee fracture or ligamentous injury on ipsilateral knee\n* neuromuscular disorder involving lower limb\n* inability\u002F unwillingness to adhere to protocol\n* anesthesia contraindications\n* lost to follow up","12 Years",{"count":133,"type":22},200,[25],"There is no consensus regarding the best surgical management of primary ACL tears. Recent evidence suggests that internal brace augmentation may increase load failure and therefore stabilize the graft in-situ at the time of ACL reconstruction. This prospective randomized controlled trial aims to compare the time to return to activity, and participant reported outcomes in participants with bone-tendon-bone ACL reconstruction with and without (control) internal brace augmentation.",[29],"NOT_YET_RECRUITING","2025-09-16",{"date":140,"type":34},"2025-09-22",{"date":142,"type":22},"2026-09",{"date":144,"type":22},"2032-09",{"name":146,"class":41},"Columbia University",{"id":148,"slug":4,"hasResults":11,"nctId":149,"briefTitle":150,"officialTitle":150,"acronym":151,"eligibilityCriteria":152,"healthyVolunteers":11,"sex":18,"minAge":153,"maxAge":154,"enrollmentInfo":155,"targetDuration":4,"studyType":23,"phases":157,"briefSummary":158,"conditions":159,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":160,"lastUpdatePostDateStruct":161,"startDateStruct":163,"completionDateStruct":165,"leadSponsor":167,"locationsCount":42},"100495748","NCT05735236","Comparison of Methods in Post Operative Knee Arthroscopy Rehabilitation","ACL BFR","Inclusion Criteria:\n\n* Patients undergoing primary knee arthroscopy for ACL reconstruction without meniscus repair\n* Completing initial 12 weeks of physical therapy at the Steadman Hawkins Clinic in Denver\n* Patients with access to smartphone device\n\nExclusion Criteria:\n\n* Bilateral knee surgeries to be performed within 12 weeks of each other\n* Patients received meniscus repairs, chondral lesion repair\u002Ftransplants,\n* Prior surgery on the same knee\n* Anyone who meets the following contraindications for BFR therapy:\n\n  * Deep Vein Thrombosis (DVT)\n\n    * Pulmonary Embolism\n    * Hemorrhagic\u002FThrombolytic Stroke\n    * Clotting Disorders\n    * Hemophilia or taking blood thinners\n    * Pregnant or up to 6 months post-partum\n    * Untreated Hypertension\n    * Untreated Hypotension\n    * Rhabdomyolysis or recent traumatic injury\n\n      2\\. Exclusion criteria will be evaluated via the medical record as well as by the expert opinion of the physician.\n\n      3\\. If at any point in the study a subject develops one of the above contraindications, they will be removed from the study.\n\n      4\\. If a subject becomes pregnant while participating in the intervention portion of the study, they will be removed.","16 Years","60 Years",{"count":156,"type":22},78,[25],"The aim of this study is to investigate the efficacy of blood flow restriction (BFR) therapy in post-operative rehabilitation following knee arthroscopy for primary ACL reconstruction. BFR has been shown to effect time to return to activity and strength postoperatively. This study aims to analyze the effects of BFR therapy in patients who underwent primary ACL reconstruction surgery compared to controls. Participants will be randomized into either a treatment (BFR Cuff) or control (no BFR cuff) group. All participants will follow standard of care (SOC) physical therapy protocol for 12 weeks after surgery according to their treatment group. Strength and patient outcome measures will be recorded throughout the 2 year study period.",[29],"2025-05-05",{"date":162,"type":34},"2025-05-08",{"date":164,"type":34},"2022-11-08",{"date":166,"type":22},"2025-11-08",{"name":168,"class":41},"University of Colorado, Denver",{"id":170,"slug":171,"hasResults":11,"nctId":172,"briefTitle":173,"officialTitle":174,"acronym":175,"eligibilityCriteria":176,"healthyVolunteers":11,"sex":18,"minAge":19,"maxAge":177,"enrollmentInfo":178,"targetDuration":4,"studyType":23,"phases":180,"briefSummary":182,"conditions":183,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":186,"lastUpdatePostDateStruct":187,"startDateStruct":189,"completionDateStruct":191,"leadSponsor":193,"locationsCount":195},"100523482","phase-2-preventing-injured-knees-from-osteoarthritis-severity-outcomes-100523482","NCT06096259","Preventing Injured Knees From osteoArthritis: Severity Outcomes","Preventing Injured Knees From osteoArthritis: Severity Outcomes (PIKASO)","PIKASO","Inclusion Criteria:\n\n1. Age 25-45 or Age 18-24 with preoperative KOOS Pain \\\u003C80 (0-100, 100 best) recorded at least 14 days after the day of ACL injury\n2. Plan to undergo ACL reconstruction within 12 months of injury\n\nExclusion Criteria:\n\n1. Inflammatory arthritis\n2. Pregnancy and\u002For lactation, or plans to become pregnant in the next 12 months\n3. Known contraindication to metformin\n4. Current use of metformin or topiramate\n5. Diabetes mellitus or diabetic ketoacidosis\n6. Acute or chronic renal insufficiency\n7. History of prior ACL tear on the index knee, with or without reconstruction\n8. History of ACL tear on the contralateral knee within the past 12 months\n9. Applying for or receiving Workers' Compensation for their knee injury\n10. Joint space narrowing AND definite osteophyte(s) on weightbearing radiograph on index knee\n11. Tibial plateau fracture on index knee\n12. Concomitant avulsion fracture of index knee that will be treated surgically\n13. Concomitant posterior cruciate ligament, medial collateral ligament, or lateral collateral ligament injury on index knee requiring surgical repair\u002Freconstruction\n14. Contraindication to MRI\n15. Unable to speak and understand English\n16. Diagnosis of cognitive impairment or otherwise unable to provide informed consent\n17. Insufficient time for recruitment and drug titration: Surgery scheduled for \\\u003C14 days from the time of screening\n18. Date of injury more than 6-months ago, relative to date of screening\n19. Presence of a condition or abnormality that in the opinion of the surgeon investigator would compromise the safety of the patient or the quality of the data\n20. Plan for allograft at time of consent","45 Years",{"count":179,"type":22},512,[181],"PHASE2","This study is being done to find out if metformin is effective at reducing pain by delaying the onset of post-traumatic osteoarthritis (PTOA) after anterior cruciate ligament (ACL) reconstruction. This research study will compare metformin to placebo. The placebo tablet looks exactly like metformin, but contains no metformin. Placebos are used in research studies to see if the results are due to the study drug or due to other reasons.\n\nMetformin is approved by the U.S. Food and Drug Administration (FDA) to treat type II diabetes. Notably, it also has anti-inflammatory effects, suggesting it could benefit people who have an ACL injury and are undergoing ACL reconstruction.",[184,185,29],"Osteoarthritis, Knee","Post-traumatic Osteoarthritis","2025-04-25",{"date":188,"type":34},"2025-04-29",{"date":190,"type":34},"2024-05-06",{"date":192,"type":22},"2029-12",{"name":194,"class":41},"Brigham and Women's Hospital",9,{"id":197,"slug":198,"hasResults":11,"nctId":199,"briefTitle":200,"officialTitle":201,"acronym":4,"eligibilityCriteria":202,"healthyVolunteers":11,"sex":18,"minAge":153,"maxAge":105,"enrollmentInfo":203,"targetDuration":4,"studyType":54,"phases":4,"briefSummary":205,"conditions":206,"keywords":4,"overallStatus":137,"whyStopped":4,"lastUpdateSubmitDate":207,"lastUpdatePostDateStruct":208,"startDateStruct":210,"completionDateStruct":212,"leadSponsor":214,"locationsCount":42},"100560315","ct-evaluation-of-acl-anatomical-reconstruction-100560315","NCT06575543","CT Evaluation of ACL Anatomical Reconstruction","Anatomical Transportal ACL Reconstruction : Effect of Using 2 or 3 Portal Technique on Femoral Tunnel Position","Inclusion Criteria:\n\n1. Age ( 16 - 50 ) .\n2. Isolated ACL tear with or without meniscal inj\n3. Patient who have undergone ACL reconstruction in the last 5 years in Arthroscopy and sports injuries unit .\n\nExclusion Criteria:\n\n* 1- Age ( \\\u003C 16 ) 2- Patient with multi ligamentous inj . 3- Revision ACL tear .",{"count":204,"type":22},72,"Our research is to evaluate the position and length of femoral tunnel, and to examine whether knee stability and clinical functional outcomes are better while using two-portal or three-portal technique .",[29],"2024-08-29",{"date":209,"type":34},"2024-09-03",{"date":211,"type":22},"2024-09-01",{"date":213,"type":22},"2025-10",{"name":215,"class":41},"Assiut University",{"id":217,"slug":218,"hasResults":11,"nctId":219,"briefTitle":220,"officialTitle":221,"acronym":4,"eligibilityCriteria":222,"healthyVolunteers":11,"sex":18,"minAge":19,"maxAge":223,"enrollmentInfo":224,"targetDuration":226,"studyType":54,"phases":4,"briefSummary":227,"conditions":228,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":235,"lastUpdatePostDateStruct":236,"startDateStruct":238,"completionDateStruct":240,"leadSponsor":241,"locationsCount":42},"100549189","exploring-prolonged-amr-in-acl-reconstructed-patients-100549189","NCT06430775","Exploring Prolonged AMR in ACL Reconstructed Patients","Exploring Prolonged Arthrogenic Muscle Responses and Associated Factors After Anterior Cruciate Ligament Reconstruction","Inclusion Criteria:\n\n* 18-40 years old.\n* Having suffered an ACL rupture.\n* Undergoing a surgical ACL reconstruction in the AZ Delta hospital in Roeselare (Campus Brugsesteenweg).\n\nExclusion Criteria:\n\n* Revision ACL reconstruction.\n* Other severe injuries to the lower limbs within the past year.\n* Muscular or neurological disorders affecting lower limb functioning.\n* Fibromyalgia or chronic fatigue syndrome.","40 Years",{"count":225,"type":22},190,"5 Months","The goal of this observational study is to explore the significance of subject-reported outcomes and clinical parameters in relation to the occurence of prolonged presence of arthrogenic muscle responses (AMR) in anterior cruciate ligament (ACL) reconstructed patients. The main questions it aims to answer are:\n\n1\\. Is there a link between the long-term occurence of AMR in ACL reconstructed patients and the level of kinesiophobia experienced before or after their ACL surgery? We hypothesize that ACL patients with higher levels of kinesiophobia are more likely to exhibit prolonged AMR as an unconscious reaction to protect their affected knee joint.\n\n2\\. Is the long-term presence of AMR in ACL reconstructed patients linked to their subjective knee function and stability (at certain time points throughout their recovery)? Our hypothesis is that poorer subjective knee function and stability might be associated with the presence of prolonged arthrogenic muscle responses in ACL reconstructed patients.\n\n3\\. Is the prolonged presence of AMR in ACL reconstructed patients linked to their pain levels (at certain time points throughout their recovery)? Our hypothesis is that ACL patients with higher pre- and\u002For postsurgical pain levels may exhibit a higher degree of long-lasting AMR.\n\n4\\. Is the long-term presence of AMR in ACL reconstructed patients linked to clinical parameters such as swelling, isometric quadriceps and hamstrings strength and knee range of motion (at certain time points throughout their recovery)? Our hypothesis is that ACL patients with poorer outcomes in terms of these clinical parameters may be more likely to exhibit prolonged AMR.\n\nParticipants will:\n\n* Fill in the following questionnaires 1 week before surgery and at 1 and 3 months after surgery:\n\n  * Demopgraphical information\n  * Knee Injury and Osteoarthritis Outcome Score (KOOS)\n  * Lysholm Score (only question 1)\n  * Tegner Activity Scale (current activity level, pre-injury activity level and desired activity level after recovery)\n  * Numeric Rating Score (NRS) for pain levels during the day \\& during the night\n  * ACL-Return to Sport after Injury Scale (ACL-RSI)\n* Complete a testing protocol 5 months after their surgery, which includes bilateral electromyographical measurements of the hamstrings and quadriceps during jumping tasks and a quadriceps inhibition measurement using the interpolated twitch method to evaluate the presence of prolonged AMR.",[229,230,231,49,28,29,232,233,234],"Anterior Cruciate Ligament Injuries","Anterior Cruciate Ligament Rupture","Anterior Cruciate Ligament Tear","Anterior Cruciate Ligament Reconstruction","Arthrogenic Muscle Inhibition","Arthrogenic Muscle Responses","2024-06-28",{"date":237,"type":34},"2024-07-01",{"date":239,"type":34},"2023-10-15",{"date":93,"type":22},{"name":242,"class":41},"University Ghent",{"id":244,"slug":245,"hasResults":11,"nctId":246,"briefTitle":247,"officialTitle":247,"acronym":4,"eligibilityCriteria":248,"healthyVolunteers":11,"sex":18,"minAge":19,"maxAge":105,"enrollmentInfo":249,"targetDuration":4,"studyType":23,"phases":250,"briefSummary":251,"conditions":252,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":254,"lastUpdatePostDateStruct":255,"startDateStruct":257,"completionDateStruct":258,"leadSponsor":260,"locationsCount":42},"100553450","geniculate-nerve-block-versus-adductor-canal-block-for-acl-reconstruction-surgery-100553450","NCT06486246","Geniculate Nerve Block Versus Adductor Canal Block for ACL Reconstruction Surgery","Inclusion Criteria:\n\n* Patients from 18 to 50 years old scheduled to undergo anterior cruciate ligament reconstruction\n\nExclusion Criteria:\n\n* peripheral neuropathy\n* pre-existing femoral neuropathy\n* diabetes mellitus\n* alcoholism\n* drug addiction\n* cancer with chemotherapy\n* chronic pain state\n* Negative of the patient to participate in the study.",{"count":85,"type":22},[25],"Anterior cruciate ligament repair (ACL) surgery presents moderate to severe pain during the inmediate postoperative period and the first days after surgery. In addition, due to the interest of surgeons and patients for early reinstatement, the use of blockages that decrease the strength of the quadriceps is avoided. Therefore, in recent years, the adductor canal block (ACB) has been used for postoperative analgesia with variable results.\n\nGenicular nerve block (GNB) has been used for pain management in patients with knee osteoarthritis and recently in knee arthroplasty surgery with results similar to the local anesthetic infiltration techniques by the surgeon (LIA). Considering their good results in these patients in addition to being a 100% sensitive block without risk of motor involvement.\n\nThe investigators proposed this experimental study to evaluate tha analgesic efficacy of the genicular nerve block (GNB) compared with the adductor canal block (ACB) for the Anterior cruciate ligament (ACL) repair surgery.",[29,253],"Pain, Postoperative","2024-06-26",{"date":256,"type":34},"2024-07-03",{"date":254,"type":34},{"date":259,"type":22},"2024-12-30",{"name":261,"class":41},"Hospital Clinic of Barcelona"]