[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"acne-scars---mixed-atrophic-and-hypertrophic\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:acne-scars---mixed-atrophic-and-hypertrophic":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,49],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":48},"100467144","efficacy-and-tolerability-of-a-hybrid-fractional-laser-for-the-treatment-of-acne-scars-in-patients-with-skin-of-color-100467144",false,"NCT05362929","Efficacy and Tolerability of a Hybrid Fractional Laser for the Treatment of Acne Scars in Patients With Skin of Color","Inclusion Criteria:\n\n* Healthy males and females, ≥ 18 years of age at time of informed consent, seeking treatment for acne scarring\n* Subject must voluntarily sign and date an IRB approved informed consent form\n* Subjects with diagnosis of acne scarring recorded over the past 6 months\n* Able to read, understand and voluntarily provide written informed consent.\n* Subject is determined to be healthy, non-smoker\n* Subjects able and willing to comply with the treatment protocol and follow-up schedule and requirements.\n* Understands and accepts the obligation not to undergo any other procedures in the areas to be treated through the follow-up period.\n\nExclusion Criteria:\n\n* Subjects does not have the capacity to consent to the study\n* subject underwent any acne scar treatments in the past 6 months prior to enrollment in the study\n* Subject has active papulopustular or cystic acne within the past 6 months.\n* Any history of keloidal scarring.\n* Any previous surgical procedure in the treatment area in the past 12 months, or major surgery in the last 6 months.\n* History of immunosuppression\u002Fimmune deficiency disorders (including AIDS and HIV infection), and\u002For any history of systemic chemotherapy for prior 12 months.\n* History or current use of the following prescription medications:\n\nImmunosuppressive medications\u002Fbiologics, 6 months prior to and during the study\n\n* Accutane or other systemic retinoids within the past twelve months\n* Smoking or vaping in the past 12 months.\n* History of photosensitivity and\u002For connective tissue disease\n* History of hyperlipidemia, diabetes mellitus, hepatitis, or bleeding disorders.\n* History of major depressive disorders or endocrine disorders including but not limited to; hypothyroidism, Hashimoto's thyroiditis, or hyperthyroidism.\n* History of ongoing pregnancy, active breastfeeding, cancer, and epilepsy",true,"ALL","18 Years",{"count":19,"type":20},46,"ESTIMATED","INTERVENTIONAL",[23],"NA","The investigators aim to investigate the efficacy and tolerability of a hybrid non-ablative\u002Fablative laser for acne scarring in skin of color.",[26,27,28],"Acne Scars - Mixed Atrophic and Hypertrophic","Hyperpigmentation","Laser-Induced Hyperpigmentation",[30,31,32,33,34,35],"skin of color","fitzpatrick skin type III","fitzpatrick skin type IV","fitzpatrick skin type V","acne scarring","sciton","RECRUITING","2025-05-20",{"date":39,"type":40},"2025-05-22","ACTUAL",{"date":42,"type":40},"2023-10-11",{"date":44,"type":20},"2026-09",{"name":46,"class":47},"Albert Einstein College of Medicine","OTHER",1,{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":53,"acronym":4,"eligibilityCriteria":54,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":55,"enrollmentInfo":56,"targetDuration":4,"studyType":21,"phases":58,"briefSummary":59,"conditions":60,"keywords":4,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":48},"100582846","avava-miria-general-use-100582846","NCT06868615","AVAVA MIRIA General Use","Inclusion Criteria:\n\n1. Male or female subjects between 18 to 70 years of age.\n2. Dermatologic condition that can be addressed by the laser, including but not limited to:\n\n   1. Wrinkles\n   2. Scars\n   3. Acne Scars\n   4. Active Acne\n   5. Dyschromia\n   6. Cutaneous Lesions such as Age or Sun Spots\n   7. Melasma\n   8. Laxity\n3. Willingness to have digital photographs taken of treatment area(s) and agreement with use of photographs for presentation, educational, or marketing purposes.\n4. Willingness to comply with the following during the study, including the follow-up period:\n\n   1. maintain consistent skin care regimen on treated areas.\n   2. cover treated areas or have very limited sun exposure and, if requested, use an approved sunscreen of SPF 50 or higher.\n   3. refrain from using systemic corticosteroids, according to Investigator discretion.\n   4. refrain from using topical corticosteroids, retinoids, or prescription skin-lightening medications on the treated areas, according to Investigator discretion.\n   5. refrain from any other procedures in the treatment areas.\n5. Willingness and ability to comply with study instructions and return for required visits.\n6. Subject has read and signed a written informed consent form.\n7. Subject lives within 50 miles of study site.\n8. Willingness to shave hair in intended treatment area\n\nExclusion Criteria:\n\n1. Skin pathology or condition that could interfere with evaluation of the study procedure, e.g.,\n2. Systemic treatment prescribed within previous 6 months (e.g., oral medication such as isotretinoin)\n3. Surgical treatment in the target areas within previous 6 months (e.g., laser surgery)\n4. Active vitiligo, psoriasis, or eczema in the treatment area\n5. Injection of dermal filler in the target areas within previous 1 month (e.g., collagen, hyaluronic acid filler)\n6. Cosmetic procedures in the target areas within prior 3 months (e.g., laser, microdermabrasion, skin peel)\n7. Topical treatment applied to target areas within the previous 1 month or according to Investigator discretion.\n8. Active suntan and unable or unlikely to refrain from tanning within the follow-up period.\n9. Artificial tanning in the target areas within the previous 1 month (e.g., spray, lotion, tanning bed) or intention to use artificial tanning within the follow-up period.\n10. Active localized or systemic infection, or an open wound in area being treated.\n11. Lesions in the treatment areas suspicious for malignancy (skin cancer, melanoma)\n12. History of abnormal wound healing or abnormal scarring (e.g., hypertrophic or keloid)\n13. History of connective tissue disease, such as lupus or scleroderma.\n14. Any use of medication that is known to increase sensitivity to light according to Investigator's discretion (e.g., topicals that produce sensitivity to light may be used in areas other than the target area).\n15. History of gold therapy.\n16. History of disease stimulated by heat, such as recurrent herpes simplex or herpes zoster (shingles) in the treatment area, unless treatment is conducted following a prophylactic regimen.\n17. History of radiation to the treatment area or currently undergoing systemic chemotherapy for the treatment of cancer.\n18. For Female: Pregnancy or lactation, or intent to become pregnant within the study period.\n19. Significant uncontrolled concurrent illness, such as diabetes mellitus or cardiovascular disease, e.g., uncontrolled hypertension.\n20. History of immunosuppression\u002Fimmune deficiency disorder or currently using immunosuppressive medications.\n21. Current enrollment in a clinical study of any other unapproved investigational drug or device\n22. Any other condition or laboratory value that would, in the professional opinion of the investigator, potentially affect response or participation in this clinical study, or would pose an unacceptable risk to the subject.","70 Years",{"count":57,"type":20},200,[23],"A general protocol to treat a variety of dermatologic conditions and collect patient feedback.\n\nPrimary outcome is the collection and analysis of patient questionnaires related to the overall experience of the device treatment. Secondary outcome measures include physician and subject evaluations in regards to improvement seen in the device as well as assessment of side effects.",[61,26,62,63,64,65],"Acne","Scars","Wrinkle","Pigment; Lesion","Skin Texture Disorder","2025-03-06",{"date":68,"type":40},"2025-03-11",{"date":70,"type":40},"2024-09-11",{"date":72,"type":20},"2027-12-30",{"name":74,"class":75},"AVAVA, Inc.","INDUSTRY"]