[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"acupoints\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:acupoints":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,51,76],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":30,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":50},"100633931","the-effect-of-cold-packs-on-hot-flushes-and-depression-in-women-going-through-the-climacteric-period-100633931",false,"NCT07533097","The Effect of Cold Packs on Hot Flushes and Depression in Women Going Through the Climacteric Period","The Effect of Applying Cold Gel Packs to the LI4 and SP6 Acupoints on Menopausal Hot Flashes and Depression in Women During the Climacteric Period","Inclusion Criteria:\n\n* In the perimenopausal phase (no menstruation for 3-11 months or an increase in irregular menstrual bleeding) or the postmenopausal phase (no menstruation for more than 12 months),\n* Participants experiencing moderate to severe hot flushes at least four times a day in the week prior to enrolment,\n* Participants who are literate in Turkish and able to communicate,\n* Participants who volunteer to take part in the study will be included in the study.\n\nExclusion Criteria:\n\n* Women who have entered menopause following surgery,\n* Women whose hot flush symptoms have decreased or ceased in the week prior to joining the study,\n* Those receiving hormone replacement therapy,\n* Those who had received herbal medication (such as black cohosh, black cohosh, ginkgo, ginseng, motherwort, valerian, black snake root, St. John's wort, etc.) or chemical medication for at least two weeks prior to joining the study,\n* Women with endocrine system disorders such as diabetes or a condition presenting symptoms similar to hot flushes,\n* Women with a regular menstrual cycle,\n* Women with a psychiatric diagnosis who are currently receiving treatment,\n* Women taking sleeping pills,\n* Women with a language barrier preventing communication in Turkish,\n* Women who are not willing to participate in the study will not be included in the research.","FEMALE",{"count":18,"type":19},80,"ESTIMATED","INTERVENTIONAL",[22],"NA","This study is planned as a pre-post test, randomised controlled, experimental trial designed to determine the effect of applying a cold gel pack to the Sanyinjiao (SP6) and Hegu (Large Intestinal 4 (LI4)) acupoints on hot flushes and depression in women during the climacteric period.",[25,26,27,28,29],"Hot Flashes","Climactericum","Perimenopausal Depression","Cold Application","Acupoints",[31,32,33,34,35,36,37],"Climacterium","hot flashes","perimenopausal depression","cold gel packs","cold application","LI4 acupoint","SP6 acupoint","NOT_YET_RECRUITING","2026-04-16",{"date":41,"type":42},"2026-04-21","ACTUAL",{"date":44,"type":19},"2026-04-13",{"date":46,"type":19},"2026-09-13",{"name":48,"class":49},"Rabia Atilla","OTHER",1,{"id":52,"slug":53,"hasResults":11,"nctId":54,"briefTitle":55,"officialTitle":55,"acronym":4,"eligibilityCriteria":56,"healthyVolunteers":57,"sex":16,"minAge":58,"maxAge":59,"enrollmentInfo":60,"targetDuration":4,"studyType":20,"phases":62,"briefSummary":63,"conditions":64,"keywords":4,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":50},"100632058","a-study-on-the-effects-and-mechanisms-of-non-invasive-acupoint-stimulation-in-intervening-in-high-stress-sensitivity-among-young-and-middle-aged-women-with-qi-stagnation-constitution-100632058","NCT07508748","A Study on the Effects and Mechanisms of Non-invasive Acupoint Stimulation in Intervening in High Stress Sensitivity Among Young and Middle-aged Women With Qi Stagnation Constitution","Inclusion Criteria:\n\n* Female, aged 20-40 years.\n* Regular daily routine with relatively fixed wake-up and bedtimes, sufficient sleep (7-9 hours), regular diet, moderate physical activity, and avoidance of shift work.\n* Intact structure of major organ systems, with no active diseases or pathological damage.\n* Regular menstrual cycle (21-35 days) and normal menstrual period (3-7 days).\n* For the experimental group (Qi Yu constitution group):\n\n  * Perceived Stress Scale (PSS-14) score ≥ 43.\n  * Qi Yu Constitution Subscale score ≥ 40.\n  * Diagnosis by a qualified TCM physician according to standard procedures, confirming characteristics of Qi Yu constitution, including (physical symptoms partially required):\n\n    * Body type: Tending to be thin.\n    * Psychological characteristics: Introverted, unstable, sensitive, suspicious, with significant emotional fluctuations.\n    * Somatic symptoms: Fullness or migrating pain in the chest and hypochondrium, frequent sighing; sensation of a foreign body in the throat (globus hystericus); sleep disturbances (difficulty falling asleep, early awakening). Poor appetite, frequent belching.\n    * Tongue and pulse: Pale red tongue with thin white coating, wiry and thin pulse.\n* For the control group (non-Qi Yu constitution group):\n\n  * Perceived Stress Scale (PSS-14) score ≤ 42.\n  * Qi Yu Constitution Subscale score \\\u003C 30.\n  * No relevant clinical manifestations upon TCM examination.\n* Signed informed consent form, voluntarily participating in the trial.\n* Willing to comply with all testing requirements.\n* No infection or bleeding tendency on the skin of the five acupoint areas (GV20\u002FBaihui, LI4\u002FHegu, LR3\u002FTaichong, PC6\u002FNeiguan, SP6\u002FSanyinjiao), not affecting the use of the study products.\n\nExclusion Criteria:\n\n* Participation in any other clinical trial evaluation within the past 1 month.\n* Presence of organic diseases, such as various malignant tumors, certain chronic diseases (heart disease, diabetes, anemia, etc.), certain gynecological diseases (uterine fibroids, endometriosis, severe mammary hyperplasia, etc.), or certain endocrine diseases (hyperthyroidism or hypothyroidism, etc.).\n* Individuals with hypothalamic-pituitary-adrenal (HPA) axis dysfunction, such as those with endocrine diseases (e.g., hyper\u002Fhypothyroidism, Cushing's syndrome, congenital adrenal hyperplasia, primary chronic adrenocortical insufficiency).\n* Individuals diagnosed with major depressive disorder or anxiety disorder, bipolar disorder, schizophrenia, etc.\n* Use of antidepressants, anti-anxiety medications, glucocorticoids, or immunosuppressants within the past 4 weeks.\n* Recent (within the past 3 months) suicidal ideation or self-harm behavior.\n* Receipt of acupuncture, massage, or other TCM treatments or psychological interventions (e.g., cognitive behavioral therapy) within the past 4 weeks.\n* Suffering from autoimmune diseases requiring long-term use of hormones.\n* Alcohol or drug dependence.\n* Experienced major stressful life events (e.g., bereavement of a close relative suffering a major psychological blow) in the past year.\n* Physically weak or unable to tolerate the arithmetic stress in the MIST task.\n* Conditions such as epilepsy, hypertension, or heart disease that are unsuitable for undergoing induced psychological stress.\n* Inability to cooperate in completing the MIST task (e.g., due to visual\u002Fauditory impairment, cognitive dysfunction).\n* Inability or unwillingness to attend all study visits and comply with the treatment regimen.",true,"20 Years","40 Years",{"count":61,"type":19},90,[22],"This is a randomized, placebo-controlled trial with a cross-over component. It investigates the effect of non-invasive acupoint stimulation on stress in young and middle-aged women. A total of 90 participants will be enrolled: 60 with a Liver-Qi Stagnation constitution and high perceived stress, and 30 without this constitution as a non-intervention baseline control. The 60 participants with the target constitution will be randomized into two groups. One group (n=30) will undergo a cross-over intervention, sequentially receiving steam-warm acupressure and simple acupressure (at five acupoints) in a randomized order, separated by a washout period. The other group (n=30) will receive placebo stimulation. The primary outcome is the change in the Perceived Stress Scale (PSS-14) score. Secondary outcomes include physiological stress responses.",[65,29],"Qi Stagnation Constitution","2026-03-27",{"date":68,"type":42},"2026-04-02",{"date":70,"type":19},"2026-04-07",{"date":72,"type":19},"2026-07-30",{"name":74,"class":75},"ChinaNorm","INDUSTRY",{"id":77,"slug":78,"hasResults":11,"nctId":79,"briefTitle":80,"officialTitle":80,"acronym":4,"eligibilityCriteria":81,"healthyVolunteers":11,"sex":16,"minAge":58,"maxAge":82,"enrollmentInfo":83,"targetDuration":4,"studyType":20,"phases":85,"briefSummary":86,"conditions":87,"keywords":4,"overallStatus":90,"whyStopped":4,"lastUpdateSubmitDate":91,"lastUpdatePostDateStruct":92,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":50},"100619986","effect-of-laser-acupoints-on-fallopian-tube-obstruction-100619986","NCT07351747","Effect of Laser Acupoints on Fallopian Tube Obstruction","Inclusion Criteria:\n\n* Women aged 20-35 years - nulliparous.\n* Women diagnosed with fallopian tube obstruction.\n* Body mass index less than 30 kg\u002Fm2.\n* Consent to participate in the study.\n* General good health with no major co-existing medical conditions that could interfere with the treatment or outcomes.\n* No prior fertility treatments \\[e.g., In vitro fertilization (IVF), intrauterine insemination (IUI)\\] within the last 6 months.\n* Ability to attend all scheduled sessions and follow-up assessments.\n\nExclusion Criteria:\n\n* Currently pregnant or breastfeeding.\n* History of pelvic surgery within the past year.\n* Presence of severe systemic diseases such as active cancer or severe cardiovascular diseases.\n* History of allergic reactions or adverse responses to acupuncture or laser therapies.\n* Currently undergoing hormonal therapy or use of hormonal contraceptives.\n* Current or recent history of genital tract infections, including sexually transmitted. infections, which could affect the reproductive system.\n* Presence of significant uterine anomalies diagnosed through imaging that could impact fertility.\n* Polycystic Ovary Syndrome (PCOS).","35 Years",{"count":84,"type":19},36,[22],"This study aims to determine the efficacy of laser acupoint therapy on treating fallopian tube obstruction.",[88,29,89],"Laser","Fallopian Tube Obstruction","RECRUITING","2026-01-10",{"date":93,"type":42},"2026-01-20",{"date":95,"type":42},"2025-04-01",{"date":97,"type":19},"2026-04-01",{"name":99,"class":49},"Kafrelsheikh University"]