[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"acupuncture-therapy\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:acupuncture-therapy":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,44,72,103,137],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":30,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100631137","effects-of-different-frequency-electroacupuncture-on-suprahyoid-muscles-in-post-stroke-dysphagia-efficacy-and-neural-networks-100631137",false,"NCT07496762","Effects of Different-Frequency Electroacupuncture on Suprahyoid Muscles in Post-Stroke Dysphagia: Efficacy and Neural Networks","Inclusion Criteria:\n\n* Diagnosis: Patients diagnosed with cerebral infarction confirmed by CT or MRI.\n* Dysphagia Screening: Presence of varying degrees of dysphagia as screened by the Water Swallow Test (WST).\n* Clinical Status: Conscious and stable vital signs, with the ability to cooperate with the treatment.\n* Age: Aged between 18 and 80 years.\n* Consent: Signed informed consent form obtained from the patient or their legal representative.\n\nExclusion Criteria:\n\n* Dysphagia Etiology: Patients with dysphagia caused by etiologies other than cerebral infarction.\n* MRI Contraindications: Patients with metal implants or pacemakers in the body (contraindications for MRI).\n* Bleeding Risk: Patients with bleeding tendencies or coagulation disorders.\n* Blood Pressure: Patients with uncontrolled hypertension (systolic blood pressure \\> 180 mmHg or diastolic blood pressure \\> 120 mmHg).\n* Organ Failure: Patients with severe failure of vital organs (e.g., heart, liver, or kidney failure).\n* Disease Severity: Patients with critical or life-threatening stroke conditions.\n* Cooperation: Patients unable to cooperate with the treatment due to severe cognitive impairment, aphasia, or other reasons.","ALL","18 Years","80 Years",{"count":19,"type":20},90,"ESTIMATED","INTERVENTIONAL",[23],"NA","This randomized controlled study in patients with post-stroke dysphagia aims to determine the optimal stimulation frequency of electroacupuncture of the suprahyoid muscles and to elucidate the underlying neural mechanisms. Participants will be assigned to low-frequency (2 Hz), medium-frequency (50 Hz), or high-frequency (100 Hz) electroacupuncture groups. Therapeutic efficacy will be assessed using the Kubota water-drinking test, videofluoroscopic swallowing study (VFSS), and ultrasonography to identify the optimal frequency. In parallel, diffusion tensor imaging (DTI) will be used to evaluate changes in fiber connectivity between swallowing-related cortical regions (bilateral precentral gyrus, insula, supramarginal gyrus, and frontal lobe) and the medullary nucleus tractus solitarius, thereby exploring neural network remodeling and providing mechanistic evidence to inform clinical practice.",[26,27,28,29],"Stroke Sequelae","Deglutition Disorders","Acupuncture Therapy","Electroacupuncture",[26,27,28,29],"NOT_YET_RECRUITING","2026-03-23",{"date":34,"type":35},"2026-03-27","ACTUAL",{"date":37,"type":20},"2026-04-21",{"date":39,"type":20},"2028-12-21",{"name":41,"class":42},"Kaili Chen","OTHER",1,{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":50,"eligibilityCriteria":51,"healthyVolunteers":11,"sex":52,"minAge":16,"maxAge":4,"enrollmentInfo":53,"targetDuration":4,"studyType":21,"phases":55,"briefSummary":56,"conditions":57,"keywords":4,"overallStatus":62,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":43},"100618715","men-with-prostate-cancer-optimizing-wellness-by-enhanced-relief-from-hot-flashes-with-acupuncture-100618715","NCT07335224","Men With Prostate Cancer: Optimizing Wellness by Enhanced Relief From Hot Flashes With Acupuncture","MPOWER: A Pilot Trial Among Men With Prostate Cancer: Optimizing Wellness by Enhanced Relief From Hot Flashes With Acupuncture","MPOWER","Inclusion Criteria:\n\n* Male\n* At least 18 years of age\n* Histologically or cytologically confirmed adenocarcinoma of prostate of any stage I-IV\n* Undergoing androgen deprivation therapy (ADT) and\u002For androgen receptor pathway inhibitors\n* Experiencing moderate to severe daily interference from hot flashes, as indicated by the Hot Flash Related Daily Interference Scale (score≥4)\n* Eastern Cooperative Oncology Group (ECOG) performance status of 0-1\n* Able to read, understand, and provide written informed consent\n\nExclusion Criteria:\n\n* Severe or uncontrolled concurrent disease, infection or co-morbidity that, in the opinion of the Investigator, would make the patient inappropriate for enrollment\n* Known hypersensitivity to the acupuncture needles\n* Any condition that in the opinion of the Investigator would impair the patients' ability to comply with the study procedures\n* Unable to comply with study requirements\n* Use of acupuncture for hot flashes within 6 months prior to enrollment","MALE",{"count":54,"type":20},24,[23],"Prostate cancer is the most common cancer among men in the United States. Many men with prostate cancer are treated with hormone therapy, also called androgen deprivation therapy (ADT). While this treatment is effective, it often causes bothersome side effects such as hot flashes, poor sleep, fatigue, and other physical and emotional symptoms. There is currently no standard treatment to help manage these side effects in men. Acupuncture is a non-drug treatment that has been shown to help reduce hot flashes and related symptoms in women receiving hormone therapy for breast cancer. However, much less is known about whether acupuncture is helpful for men receiving hormone therapy for prostate cancer. This study will test whether an acupuncture program, combined with usual lifestyle education, is feasible and acceptable for men undergoing ADT. The study will also explore whether acupuncture may help reduce hot flashes and improve related symptoms. A total of 24 men with prostate cancer receiving ADT will be randomly assigned to one of two groups: one group will begin acupuncture right away, and the other group will begin acupuncture after a delay, with regular check-ins during the waiting period. All participants will receive standard lifestyle education. Participants will be followed for about five months and will be asked to complete daily hot flash diaries, questionnaires about their symptoms and quality of life, and wear a Fitbit to track sleep. The results of this pilot study will help determine whether a larger study should be conducted to better understand the role of acupuncture in managing hormone therapy side effects in men with prostate cancer.",[58,28,59,60,61],"Hot Flashes","Vasomotor Symptoms","Androgen Deprivation Therapy","Prostatic Neoplasms","RECRUITING","2026-02-02",{"date":65,"type":35},"2026-02-04",{"date":67,"type":35},"2026-01-08",{"date":69,"type":20},"2027-06-30",{"name":71,"class":42},"Inova Health Care Services",{"id":73,"slug":74,"hasResults":11,"nctId":75,"briefTitle":76,"officialTitle":77,"acronym":4,"eligibilityCriteria":78,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":79,"enrollmentInfo":80,"targetDuration":4,"studyType":21,"phases":82,"briefSummary":83,"conditions":84,"keywords":89,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":43},"100609160","scalp-acupuncture-combined-with-rtms-for-upper-limb-motor-dysfunction-in-stroke-a-brain-network-study-100609160","NCT07210944","Scalp Acupuncture Combined With rTMS for Upper Limb Motor Dysfunction in Stroke: A Brain Network Study","Research Protocol for a Randomized Controlled Trial on Brain Network Study of Upper Limb Motor Dysfunction in Stroke Patients Treated With Scalp Acupuncture Combined With rTMS","Inclusion Criteria:\n\n* Meet the diagnostic criteria for stroke (symptoms and signs, imaging indicators, etc.), and are independently diagnosed by two deputy chief physicians\n* Age 18-70 years old, first episode, duration 1-6 months\n* The diagnostic criteria for upper limb dysfunction align with the Brunnstrom staging system: patients in Brunnstrom stages II to IV. Stage II: patients exhibit associative responses and can perform coordinated movements, with minimal voluntary movements; Stage III: patients show voluntary coordinated movements, such as grasping with the hand but not extending; Stage IV: patients can perform isolated movements, such as pinching with the hand and limited extension\n* No severe visual or hearing impairment, able to cooperate with relevant assessments and tests\n* The score of the Mini-Mental State Examination is ≥20 points\n* Vital signs are stable, with no signs of progressive neurological symptoms\n* The patient or legal guardian agrees and signs the informed consent form\n\nExclusion Criteria:\n\n* Severe visual impairment, hemispatial neglect, body image disorder\n* Individuals who cannot undergo rTMS treatment due to reasons such as metal implants, cardiac pacemakers, or skull defects\n* Previous history of brain tumor, brain trauma, epilepsy, and risk of epileptic seizures\n* Any other factors that affect assessment and treatment\n* Dysfunction of limb movement caused by other reasons (such as trauma, etc.)","70 Years",{"count":81,"type":20},44,[23],"This study aims to compare the improvement effects of the rTMS (repetitive transcranial magnetic stimulation) combined with conventional rehabilitation therapy group with the rTMS combined with scalp acupuncture and conventional rehabilitation therapy group. Through statistical analysis of the results obtained from functional near-infrared spectroscopy technology during task states, the investigators elucidate the neuroregulatory mechanism of scalp acupuncture combined with rTMS in improving upper limb motor function in stroke patients under MEP localization, and provide evidence for a more optimal rehabilitation program for post-stroke upper limb motor dysfunction.",[85,28,86,87,88],"Upper Extremity","Stroke","Transcranial Magnetic Stimulation Repetitive","Motor Disorders",[90,91,92,93,88],"Conventional rehabilitation therapy","Scalp Acupuncture","Upper Limb","Repetitive Transcranial Magnetic Stimulation","2025-11-18",{"date":96,"type":35},"2025-11-19",{"date":98,"type":20},"2025-12-05",{"date":100,"type":20},"2027-05-30",{"name":102,"class":42},"Debiao Kong",{"id":104,"slug":105,"hasResults":11,"nctId":106,"briefTitle":107,"officialTitle":108,"acronym":109,"eligibilityCriteria":110,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":111,"targetDuration":4,"studyType":21,"phases":113,"briefSummary":114,"conditions":115,"keywords":124,"overallStatus":62,"whyStopped":4,"lastUpdateSubmitDate":128,"lastUpdatePostDateStruct":129,"startDateStruct":131,"completionDateStruct":133,"leadSponsor":135,"locationsCount":43},"100602461","acuknee-role-of-acupuncture-in-knee-prosthetic-surgery-100602461","NCT07123805","ACU_Knee: Role of Acupuncture in Knee Prosthetic Surgery","ACU_Knee - Role of Acupuncture in Knee Prosthetic Surgery: Analgesia, Functional Outcome and Inflammatory Markers","ACU_Knee","Inclusion Criteria:\n\n* Patients aged \\> 18 years\n* Patients capable of providing informed consent\n* Unilateral total knee replacement surgery\n* Indication for surgery: primary osteoarthritis degeneration\n* Surgery performed electively\n\nExclusion Criteria:\n\n* Patients aged \\\u003C 18 years\n* Patients incapable of providing informed consent\n* Patients with ASA class \\> 3\n* Pregnant women\n* Patients with rheumatoid arthritis or other autoimmune disorders\n* Patients with active infection under antibiotic treatment\n* Patients on chronic opioid therapy\n* Patients on chronic biological drug therapy\n* Patients with a history of corticosteroid use in the six months prior to surgery\n* Patients with a history of periarticular infiltration in the three months prior to surgery\n* Patients in whom loco-regional anesthesia is contraindicated\n* Patients in whom NSAID, cortisone, and paracetamol therapy is contraindicated\n* Bilateral total knee replacement surgery or prosthetic revision surgeries\n* Indication for surgery for causes other than primary osteoarthritis degeneration",{"count":112,"type":20},80,[23],"Post-operative analgesia after total knee arthroplasty (TKA) has always been a challenge in the anesthesiological setting, having to combine good pain control and the need for early mobilization, both factors that can affect the quality of rehabilitation treatment, prosthetic functional outcome, the onset of chronic pain, joint stiffness and the consequent quality of life of the patient. Recent loco-regional anesthesia (LRA) techniques have made an essential contribution to peri-operative management in the fast-track perspective of surgery, in terms of optimization of analgesia and rapid functional recovery. Inadequate post-operative analgesia, by affecting the normal rehabilitation pathway, is associated with medium-long term complications, such as chronic pain, joint stiffness and patient dissatisfaction, which often compromise functional autonomy and quality of life of the patient and may require invasive treatments (surgical revision, unlocking under general anesthesia). The local and systemic inflammatory state, evidenced by peri-operative dosage of specific biomarkers, appears to be related to prosthetic outcome.",[116,117,28,118,119,120,121,122,123],"Acupuncture Analgesia","Acupuncture","Total Knee Anthroplasty","Postoperative Pain Management","Pain Threshold","Shoulder Pain","Laparoscopies","Acupuncture Ear",[125,126,127],"acupuncture","total knee arthroplasty","pain","2025-08-08",{"date":130,"type":35},"2025-08-14",{"date":132,"type":35},"2024-04-10",{"date":134,"type":20},"2026-12-31",{"name":136,"class":42},"Fondazione IRCCS Policlinico San Matteo di Pavia",{"id":138,"slug":139,"hasResults":11,"nctId":140,"briefTitle":141,"officialTitle":142,"acronym":143,"eligibilityCriteria":144,"healthyVolunteers":11,"sex":15,"minAge":145,"maxAge":146,"enrollmentInfo":147,"targetDuration":4,"studyType":21,"phases":149,"briefSummary":152,"conditions":153,"keywords":156,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":166,"lastUpdatePostDateStruct":167,"startDateStruct":169,"completionDateStruct":171,"leadSponsor":172,"locationsCount":4},"100591617","phase-1-acupuncture-versus-compound-diclofenac-sodium-for-pain-relief-in-non-traumatic-acute-abdominal-100591617","NCT06982755","Acupuncture Versus Compound Diclofenac Sodium for Pain Relief in Non-Traumatic Acute Abdominal","Effect of Acupuncture on Early Analgesia of Non-traumatic Acute Abdomen is Discussed Based on the Experience of Sanli Acupoint for Du-fu Diseases :A Prospective Randomized Controlled pRCT Study","ACU-NTAA","Inclusion Criteria:\n\n1. The diagnostic criteria of NTAA were as follows: ① abdominal pain was the main symptom; ② The onset time was less than 1 week; ③ The cause of abdominal pain could be traced to intra-abdominal abdominal wall chest or systemic diseases;\n2. Patients with NRS scores ≥4 (mild pain and above) were evaluated before inclusion; （3）16 years \\\u003C age \\\u003C75 years;\n\n（4）Those who were considered not to need surgery within 2 hours after initial assessment by a specialist.\n\nExclusion Criteria:\n\nParticipants meeting any of the following criteria were excluded from the study:\n\n1. Acute abdomen caused by trauma;\n2. Super sudden diseases (e.g. acute myocardial infarction rupture of abdominal aortic aneurysm pulmonary embolism aortic dissection pericardial tamponade);\n3. Emergent conditions requiring surgical treatment within 3 hours (e.g. rupture of liver cancer ectopic pregnancy ischemic bowel disease severe acute cholangitis peritonitis with septic shock);\n4. Extremely severe pain (NRS ≥ 8) with an undetermined diagnosis and requiring further assessment for a super sudden disease;\n5. Inability to select acupuncture points due to skin injury or ulceration at Zusanli (ST36) on the lower limb;\n6. Induration or infection at the hip injection site;\n7. Patients with altered consciousness mental illness other severe chronic diseases or those who are unlikely to cooperate with acupuncture treatment;\n8. Contraindications to Western medicine:\n\n   * Known allergies to diclofenac sodium or acetaminophen; ②History of asthma urticaria or allergic reactions induced by aspirin or other NSAIDs.\n\n     * Undergoing coronary artery bypass grafting (CABG) surgery. ④History of gastrointestinal bleeding or perforation following non-steroidal anti-inflammatory drugs (NSAIDs).\n\n       * Active gastrointestinal ulcers or bleeding or a history of recurrent ulcers or bleeding.\n\n         * Severe heart failure.\n9. Use of any pain medication or acupuncture within the past 6 hours;\n10. Previous participation in this study;\n11. Pregnant or lactating individuals.","16 Years","75 Years",{"count":148,"type":20},176,[150,151],"PHASE1","PHASE2","The investigators designed this clinical study to evaluate the efficacy and safety of semi-standardized acupuncture and moxibustion combined with compound diclofenac sodium injection in the emergency department (ED) compared with acupuncture or compound diclofenac sodium injection alone.",[154,28,117,155],"Acute Abdominal Pain","Opioids",[157,158,159,160,117,161,162,163,155,164,165],"Acute abdominal pain","Non-Traumatic Acute Abdomen","Non-traumatic acute abdomen early analgesia","Acupuncture therapy","Zusanli point, ST36","Diclofenac sodium","Emergency environment","Non-steroidal anti-inflammatory drugs ，NSAIDs","Acetaminophen","2025-05-20",{"date":168,"type":35},"2025-05-21",{"date":170,"type":20},"2025-06-01",{"date":134,"type":20},{"name":173,"class":42},"The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine"]