[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"acupuncture\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:acupuncture":29},{"pageToken":4,"total":5,"offset":6,"count":7,"results":8},null,31,0,25,[9,53,84,113,141,166,194,219,247,273,297,323,346,376,398,422,454,478,514,539,562,585,608,630,656],{"id":10,"slug":11,"hasResults":12,"nctId":13,"briefTitle":14,"officialTitle":15,"acronym":16,"eligibilityCriteria":17,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":25,"briefSummary":27,"conditions":28,"keywords":35,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":41,"lastUpdatePostDateStruct":42,"startDateStruct":45,"completionDateStruct":47,"leadSponsor":49,"locationsCount":52},"100582242","acupuncture-for-adhd-acupoint-data-mining-clinical-effectiveness-and-interviews-to-explore-treatment-outcomes-100582242",false,"NCT06860763","Acupuncture for ADHD: Acupoint Data Mining, Clinical Effectiveness, and Interviews to Explore Treatment Outcomes.","Clinical Study on Acupuncture Treatment for Attention Deficit Hyperactivity Disorder.","ACU-ADHD","Inclusion Criteria:\n\nPatients will be considered for enrolment if they meet the criteria of:\n\n* A confirmed diagnosis of ADHD based on the DSM-5 criteria for ADHD (Western medical diagnosis) and in accordance with the ADHD Chinese Medicine Clinical Trial Design and Evaluation Technical Guidelines.\n* Aged between 6 and 12 years.\n* No use of any other pharmacological treatments (both Western and traditional Chinese medicine) within the two weeks prior to the start of the study.\n* An IQ score of greater than 80, as determined by the Raven's Progressive Matrices test.\n* The participant has not participated in any other clinical trials.\n\nExclusion Criteria:\n\nPatients will be excluded from the study if they meet any of the following criteria:\n\n* Do not meet the inclusion criteria\n* Have comorbid psychiatric disorders, severe medical or psychiatric conditions that may interfere with the study (e.g., epilepsy, severe anxiety), pervasive developmental disorders, intellectual disability, or a history of suicidal or self-harming behavior\n* Have participated in any other drug clinical trials within the past 3 months.\n* Have severe comorbid conditions such as cardiovascular, hepatic, renal, or hematologic diseases.\n* Have any other conditions that the researchers believe may interfere with the assessment of treatment efficacy or safety.","ALL","6 Years","12 Years",{"count":22,"type":23},120,"ESTIMATED","INTERVENTIONAL",[26],"NA","This study aims to evaluate the efficacy of acupuncture as a treatment for Attention Deficit Hyperactivity Disorder (ADHD) in children aged 6-12 years. Using a mixed-methods approach, the research will triangulate data from acupoint data mining, treatment outcomes assessment, and patient perspectives to provide a comprehensive analysis of acupuncture's potential therapeutic benefits for ADHD.\n\nThis prospective cohort study will recruit children diagnosed with ADHD, assigning them to receive either acupuncture combined with traditional Chinese herbal treatment or herbal treatment alone. Quantitative assessments using the the SNAP-IV, Conners 3-P, BRIEF-2, PedsQL™ 4.0 Generic Core Scales, PSQI and CGI that will be complemented by qualitative interviews to capture nuanced patient experiences and treatment outcomes.\n\nThe study will span 12 months, commencing on March 1st, 2025 with an expected completion by February 28th, 2026. By integrating quantitative assessments with qualitative insights, it aims to provide comprehensive evidence on acupuncture's role in ADHD management. Findings may inform clinical guidelines and enhance patient-centered care approaches.",[29,30,31,32,33,34],"Acupuncture","ADHD - Attention Deficit Disorder With Hyperactivity","Children","Interview","Executive Functioning","Quality of Life (QOL)",[29,36,37,32,38,39],"ADHD","Executive functioning","TCM","PedsQL","RECRUITING","2026-06-21",{"date":43,"type":44},"2026-06-23","ACTUAL",{"date":46,"type":44},"2024-10-15",{"date":48,"type":23},"2027-01-31",{"name":50,"class":51},"The Third Affiliated Hospital of Beijing University of Chinese Medicine","OTHER",1,{"id":54,"slug":55,"hasResults":12,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":4,"eligibilityCriteria":59,"healthyVolunteers":12,"sex":18,"minAge":60,"maxAge":61,"enrollmentInfo":62,"targetDuration":4,"studyType":24,"phases":64,"briefSummary":65,"conditions":66,"keywords":69,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":4},"100641065","efficacy-and-mechanism-of-yanjiu-needle-for-pharyngeal-dysphagia-based-on-semg-features-100641065","NCT07656025","Efficacy and Mechanism of 'Yanjiu Needle' for Pharyngeal Dysphagia Based on sEMG Features","Therapeutic Efficacy and Mechanistic Study of Yanjiu Acupuncture in Patients With Pharyngeal Dysphagia Based on Surface Electromyographic Features","Inclusion Criteria:\n\n* First onset of stroke with swallowing disorders lasting for 2 weeks to 6 months;\n* Stable vital signs, able to understand and execute physician instructions, and cooperate with treatment;\n* Age range: 40-75 years old, male or female not limited;\n* Functional Oral Intake Scale (FOIS) classification ≤ 4;\n* The patient's surgical site can receive acupuncture treatment;\n* Informed consent from patients or family members.\n\nExclusion Criteria:\n\n* Individuals with unstable vital signs who are unable to complete assessment and treatment;\n* Individuals with severe cognitive impairment, communication barriers, or other mental illnesses who are unable to cooperate with treatment;\n* Individuals with a history of oral, pharyngeal, and esophageal structural abnormalities, cricopharyngeal muscle stenosis, and cancer;\n* Confirmed by cranial CT\u002FMRI as a deceased with brainstem infarction\u002Fhemorrhage and extensive cerebral infarction;\n* Participants in other clinical trials;\n* Those who cannot accept surface electromyography examination; Pregnant and lactating women.","40 Years","75 Years",{"count":63,"type":23},100,[26],"Dysphagia is one of the most common and serious complications following stroke. It can easily lead to aspiration and aspiration pneumonia, reduce patients' quality of life, increase healthcare costs, and result in high mortality rates, making it a clinical issue that urgently needs to be addressed. Current mainstream therapies have limitations: neurostimulation targets a single pathway, while rehabilitation training offers only limited improvement in microcirculation and suffers from low patient compliance. Although acupuncture shows promise, it lacks high-quality randomized controlled evidence, and the specific acupuncture techniques lack standardized operational protocols, limiting their widespread adoption. In preliminary clinical practice, Chen Xiaokai, a renowned traditional Chinese medicine practitioner in Guangdong Province, developed the \"Nine Pharyngeal Acupoints\" (including Lianquan and Renying) based on the \"resolving knots\" theory. This approach can rapidly improve pharyngeal muscle tone and swallowing function. Basic research has confirmed that stimulation of these acupoints promotes pharyngeal circulation, activates the brainstem, and aids in the restoration of the swallowing reflex. This study aims to conduct a single-center, assessor-blinded, randomized, controlled, prospective superiority clinical trial. Using surface electromyography (EMG) as the core assessment tool, combined with swallowing videofluoroscopy and functional scales, the study will analyze the efficacy and neuro-muscular regulatory mechanisms of the \"Nine Pharyngeal Acupoints\" technique. The study is expected to clarify its therapeutic efficacy, establish standard operating procedures, and provide a basis for clinical implementation.",[29,67,68],"Dysphagia","Surface EMG",[70,67,71,29,72,73],"Stroke","Nine needles for swallowing","Clinical research","mechanism","NOT_YET_RECRUITING","2026-06-16",{"date":77,"type":44},"2026-06-18",{"date":79,"type":23},"2026-06-20",{"date":81,"type":23},"2028-12-20",{"name":83,"class":51},"The Third People's Hospital of Huizhou",{"id":85,"slug":86,"hasResults":12,"nctId":87,"briefTitle":88,"officialTitle":89,"acronym":90,"eligibilityCriteria":91,"healthyVolunteers":12,"sex":92,"minAge":93,"maxAge":4,"enrollmentInfo":94,"targetDuration":4,"studyType":24,"phases":96,"briefSummary":97,"conditions":98,"keywords":101,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":104,"lastUpdatePostDateStruct":105,"startDateStruct":107,"completionDateStruct":109,"leadSponsor":111,"locationsCount":52},"100603093","stress-reduction-through-acupuncture-100603093","NCT07132034","Stress Reduction Through Acupuncture","Study Protocol: Stress Reduction in Breast Cancer Patients During Transition Into Survivorship Using Acupuncture - a Randomized Wait-list-controlled Intervention Study","STREAK","Inclusion criteria:\n\n* Patients with localized breast cancer having completed primary therapy (operation +\u002F- chemotherapy +\u002F- radiotherapy) in the last 6 months - Distress Thermometer ≥ 5 - Age ≥ 18 years - Signed informed consent for participation of the trial\n* Prior cancer is allowed\n* Prior treatment - including chemotherapy - for a prior malignant tumor (including breast cancer) is allowed\n* Concomitant participation in an experimental therapeutic drug trial is allowed\n* Ongoing or planned Anti-her2\u002Fneu, immune checkpoint inhibitor, antihormonal and CDK4\u002F6 inhibitor therapy or other adjuvant treatment scheduled for \\> 3 months during study period is allowed\n* Use of other complementary methods (including mistletoe) is allowed.\n\nExclusion criteria:\n\n* Patients with language or cognitive deficits (including impaired consciousness) that are incompatible with the participation in the study\n* Severe physical or psychiatric comorbidity that prevents a patient from participating in the study\n* Patients incapable of giving consent\n* Pregnancy","FEMALE","18 Years",{"count":95,"type":23},112,[26],"This randomized controlled trial evaluates whether eight weeks of weekly acupuncture can reduce psychological distress in breast cancer patients who have recently completed primary therapy compared to standard-of-care wait-list control.",[29,99,100],"Breast Cancer","Survivorship",[102,29,99,100,103],"Integrative Oncology","Distress","2026-05-19",{"date":106,"type":44},"2026-05-22",{"date":108,"type":23},"2026-06",{"date":110,"type":23},"2028-09",{"name":112,"class":51},"Isabell Xiang Ge",{"id":114,"slug":115,"hasResults":12,"nctId":116,"briefTitle":117,"officialTitle":117,"acronym":4,"eligibilityCriteria":118,"healthyVolunteers":12,"sex":92,"minAge":119,"maxAge":120,"enrollmentInfo":121,"targetDuration":4,"studyType":24,"phases":123,"briefSummary":124,"conditions":125,"keywords":128,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":131,"lastUpdatePostDateStruct":132,"startDateStruct":134,"completionDateStruct":136,"leadSponsor":138,"locationsCount":52},"100545950","acupuncture-for-chronic-pelvic-pain-100545950","NCT06388590","Acupuncture for Chronic Pelvic Pain","\\*\\*Patients must be able to get care at Nellis Air Force Base (a military installation) in order to participate in this study\\*\\*\n\nInclusion Criteria:\n\n* Active Duty and DoD Female Beneficiaries (i.e. former military, spouse, dependent) aged 21-65 with chronic pelvic pain\n* Have negative laparoscopic findings for endometriosis\n\nExclusion Criteria:\n\n* Severe mental health disorders to include any disorder with psychotic features (e.g schizophrenia, bipolar, schizoaffective disorder)\n* Pelvic pain as a result of severe physical trauma (excluding sexual assault) such as traumatic childbirth, pelvic fractures or any other trauma as determined by the PI or AI.\n* Pregnancy","21 Years","65 Years",{"count":122,"type":23},64,[26],"The objective of this study is to determine if alternative pain management strategies, namely acupuncture, may help reduce intensity of female pelvic pain compared to other pain control modalities. This research study will focus specifically on the Dragon's protocol of acupuncture which will seek to alleviate chronic non-endometriosis pelvic pain for women both with and without a history of sexual assault.\n\nThis study may support evidence for an inexpensive alternative means of treatment for patients with or without traumatic sexual history and chronic pelvic pain.",[126,29,127],"Pelvic Pain","Gynecology",[129,130],"integrative medicine","acupuncture","2026-04-09",{"date":133,"type":44},"2026-04-14",{"date":135,"type":44},"2024-12-01",{"date":137,"type":23},"2026-10",{"name":139,"class":140},"David Moss","FED",{"id":142,"slug":143,"hasResults":12,"nctId":144,"briefTitle":145,"officialTitle":146,"acronym":147,"eligibilityCriteria":148,"healthyVolunteers":12,"sex":18,"minAge":93,"maxAge":4,"enrollmentInfo":149,"targetDuration":4,"studyType":24,"phases":151,"briefSummary":152,"conditions":153,"keywords":4,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":131,"lastUpdatePostDateStruct":158,"startDateStruct":159,"completionDateStruct":161,"leadSponsor":163,"locationsCount":165},"100232534","hypoglossal-acupuncture-for-dysgeusia-in-patients-undergoing-chemotherapy-100232534","NCT02304913","Hypoglossal Acupuncture for Dysgeusia in Patients Undergoing Chemotherapy","Hypoglossal Acupuncture for Dysgeusia in Gynecologic Cancer Patients Undergoing Chemotherapy: A Randomized Controlled Trial","OralAcu","Inclusion Criteria:\n\n* Initial treatment with platinum-containing or taxane-based CTX (regardless of the the length of the CTX cycle)\n* Senological, gynecological or internistic tumors\n* Phantogeusia (on average ≥4 NRS)\n* Willingness to participate in the study and written informed consent\n\nExclusion Criteria:\n\n* Severe stomatitis\n* Dysgeusia before the CTX based on neurological diseases, diabetes, or the ingestion of drugs with taste disorders as side effects\n* Leucopenia\u002Fneutropenia\n* Intake of anticoagulants\n* Smoking\n* Severe physical or mental comorbidity (due to which the patient is unable to participate in the study)\n* Participation in other CAM treatments within the integrative oncology care\n* Participation in other studies on the effectiveness of interventions for oral complications",{"count":150,"type":23},75,[26],"This randomized controlled trial aims to investigate hypoglossal acupuncture in comparison to sham acupuncture and standard medical treatment (dietary recommendations) in the treatment of dysgeusia in cancer patients undergoing chemotherapy.",[29,154,155,156,157],"Taste Disorders","Dysgeusia","Chemotherapy","Cancer",{"date":133,"type":44},{"date":160,"type":44},"2015-01-01",{"date":162,"type":23},"2027-12-31",{"name":164,"class":51},"Universität Duisburg-Essen",3,{"id":167,"slug":168,"hasResults":12,"nctId":169,"briefTitle":170,"officialTitle":171,"acronym":4,"eligibilityCriteria":172,"healthyVolunteers":173,"sex":18,"minAge":93,"maxAge":174,"enrollmentInfo":175,"targetDuration":4,"studyType":24,"phases":177,"briefSummary":178,"conditions":179,"keywords":182,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":185,"lastUpdatePostDateStruct":186,"startDateStruct":188,"completionDateStruct":190,"leadSponsor":192,"locationsCount":4},"100633121","efficacy-of-acupuncture-on-chronic-tinnitus-and-its-association-with-auditory-brainstem-response-measures-100633121","NCT07522567","Efficacy of Acupuncture on Chronic Tinnitus and Its Association With Auditory Brainstem Response Measures","Efficacy of Acupuncture on Chronic Tinnitus and Its Association With Auditory Brainstem Response Measures: A Study Protocol for a Matched Case-Control and Self-Controlled Trial","Inclusion Criteria:\n\n1. Aged between 18 and 60 years, inclusive, any sex;\n2. No previous chronic functional or organic diseases, no head injury;\n3. No history of any psychiatric or neurological family genetic disease;\n4. Signed a paper version of the informed consent form and volunteered to participate in this trial.\n\nExclusion Criteria:\n\n1. Pregnant or breastfeeding women, and those who have a request for childbearing within the last six months;\n2. History of head trauma;\n3. Presence of metallic implants in the body or any other contraindication to ABR testing;\n4. Current participation in any other interventional clinical trial.",true,"60 Years",{"count":176,"type":23},72,[26],"The goal of this clinical trial is to learn if acupuncture works to treat chronic tinnitus in adults. It will also learn about the neurophysiological effects of acupuncture on auditory conduction pathway function. The main questions it aims to answer are:\n\nDoes acupuncture lower tinnitus-related disability and severity, as measured by the Tinnitus Handicap Inventory (THI) and Tinnitus Effects Questionnaire (TEQ)?\n\nWhat changes in auditory brainstem response (ABR) parameters-such as wave I amplitude and wave V latency-occur after acupuncture treatment, and do these changes correlate with clinical improvement?\n\nResearchers will compare ABR parameters and clinical outcomes between chronic tinnitus patients and age- and sex-matched healthy controls to characterize tinnitus-related abnormalities. Additionally, the study will evaluate changes within the patient group before and after a 10-session acupuncture course to assess treatment efficacy and explore its neurophysiological mechanisms.",[180,29,181],"Tinnitus","Auditory Brainstem Response",[183,130,184],"tinnitus","auditory brainstem response","2026-04-04",{"date":187,"type":44},"2026-04-13",{"date":189,"type":23},"2026-12-31",{"date":191,"type":23},"2027-07-31",{"name":193,"class":51},"The Third Affiliated hospital of Zhejiang Chinese Medical University",{"id":195,"slug":196,"hasResults":12,"nctId":197,"briefTitle":198,"officialTitle":199,"acronym":4,"eligibilityCriteria":200,"healthyVolunteers":12,"sex":18,"minAge":93,"maxAge":201,"enrollmentInfo":202,"targetDuration":4,"studyType":24,"phases":204,"briefSummary":205,"conditions":206,"keywords":208,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":210,"lastUpdatePostDateStruct":211,"startDateStruct":213,"completionDateStruct":215,"leadSponsor":217,"locationsCount":52},"100630917","acupuncture-for-post-stroke-dysphagia-a-clinical-study-100630917","NCT07493902","Acupuncture for Post-Stroke Dysphagia: A Clinical Study","Acupuncture Treatment for Post-Stroke Dysphagia: A Prospective, Multicenter Clinical Study of a Cohort-Based Embedded Partially Randomized Preference Trial","Inclusion Criteria:\n\n* Age between 18 and 80 years old, no gender restrictions;\n\n  * Meets diagnostic criteria for ischemic or hemorrhagic stroke, confirmed by CT or MRI, with disease duration within one year;\n\n    * Meets diagnostic criteria for dysphagia, with FOIS grade 2-4;\n\n      * Vital signs stable, able to understand and cooperate with study procedures; ⑤ Patient or legal representative agrees to sign informed consent.\n\nExclusion Criteria:\n\n* Dysphagia not caused by stroke, but resulting from other neurological disorders (e.g., motor neuron disease, myasthenia gravis) or organic lesions (e.g., tumors);\n\n  * Patients with psychiatric disorders or severe cognitive impairment who cannot cooperate with treatment;\n\n    * Patients with an expected survival time of less than 3 months; ④ Individuals with contrast medium allergy;\n\n      * Patients with severe needle phobia who cannot tolerate the procedure; ⑥ Pregnant women, those planning pregnancy, or lactating women; ⑦ Individuals who have participated in other clinical trials or received acupuncture within the past week.","80 Years",{"count":203,"type":23},3232,[26],"Employing a nested design, a partially randomized preference study (Study II) is embedded within a prospective, multicenter cohort study (Study I). The cohort study, with acupuncture as the exposure factor, explores the clinical efficacy and health economic value of different integrated Chinese and Western medicine treatment protocols. The nested partially randomized preference study of different acupuncture protocols generates high-level evidence through randomized cohorts while supplementing real-world decision-making with preference cohort data.",[207,29],"Post-stroke Dysphagia",[209,130],"post-stroke dysphagia","2026-03-20",{"date":212,"type":44},"2026-03-25",{"date":214,"type":23},"2026-04",{"date":216,"type":23},"2028-04",{"name":218,"class":51},"First Teaching Hospital of Tianjin University of Traditional Chinese Medicine",{"id":220,"slug":221,"hasResults":12,"nctId":222,"briefTitle":223,"officialTitle":224,"acronym":4,"eligibilityCriteria":225,"healthyVolunteers":12,"sex":92,"minAge":226,"maxAge":227,"enrollmentInfo":228,"targetDuration":4,"studyType":24,"phases":230,"briefSummary":232,"conditions":233,"keywords":4,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":237,"lastUpdatePostDateStruct":238,"startDateStruct":240,"completionDateStruct":242,"leadSponsor":244,"locationsCount":246},"100555336","phase-3-a-trial-of-chinese-traditional-medicine-combining-with-intradermal-acupuncture-for-treating-precocious-puberty-100555336","NCT06510764","A Trial of Chinese Traditional Medicine Combining With Intradermal Acupuncture for Treating Precocious Puberty","A Randomized Controlled Trial of Ziyin-Xiehuo Chinese Medicine Herbs Combined With Intradermal Acupuncture for the Treatment of Girl's Idiopathic Precocious Puberty With Yin Deficiency and Fire Hyperactivity","Inclusion Criteria:\n\n* Girls are diagnosed as Idiopathic precocious puberty, and their age of onset ≤7.5years;\n* Tanner stages of breast in female patients ≤ Tanner III stage, diameters of mammillary nucleus ≤ 3cm; •B-type ultrasonography: the volume of uterus≥ 3ml, the volume of ovary≥1.5ml, the diameter of follicle≥4mm;\n* Bone age: compared the chronological age, the bone age is less than 1 year and the bone age \\\u003C10 years old;\n* No GnRH analogs or Sex hormones were administrated in the past; and All above are needed at the same time.\n\nExclusion Criteria:\n\n* Precocity caused by the central nervous system organic diseases;\n* Precocious precocity caused by congenital hypothyroidism, congenital adrenal hyperplasia, adrenal tumor and ovarian or testicular neoplasms as well as McCune-Albright syndrome, etc;\n* Precocious precocity with a family history of diseases such as tumor, leukemia, diabetes, systemic lupus erythematous;\n* Pseudo sexual precocity and partial precocious puberty.","4 Years","9 Years",{"count":229,"type":23},170,[231],"PHASE3","A randomized controlled study will be conducted to evaluate the therapeutic effect of traditional Chinese medicine and acupoints stimulation on children with idiopathic precocious puberty.",[234,235,236,29],"Precocious Puberty","Treatment","Alternative Medicine","2026-03-13",{"date":239,"type":44},"2026-03-16",{"date":241,"type":44},"2024-09-15",{"date":243,"type":23},"2027-07-01",{"name":245,"class":51},"Children's Hospital of Fudan University",2,{"id":248,"slug":249,"hasResults":12,"nctId":250,"briefTitle":251,"officialTitle":252,"acronym":253,"eligibilityCriteria":254,"healthyVolunteers":12,"sex":92,"minAge":93,"maxAge":4,"enrollmentInfo":255,"targetDuration":4,"studyType":24,"phases":256,"briefSummary":257,"conditions":258,"keywords":261,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":264,"lastUpdatePostDateStruct":265,"startDateStruct":267,"completionDateStruct":269,"leadSponsor":271,"locationsCount":52},"100575190","the-use-of-acupuncture-to-reduce-chemotherapy-induced-peripheral-neuropathy-in-gynaecological-cancer-patients-100575190","NCT06769061","The Use of Acupuncture to Reduce Chemotherapy Induced Peripheral Neuropathy in Gynaecological Cancer Patients","The Use of Acupuncture to Reduce Chemotherapy Induced Peripheral Neuropathy (CIPN) in Gynaecological Cancer Patients - A Pilot Randomised Controlled Trial","AcuCIN","Inclusion Criteria:\n\n* Age 18 or above\n* Diagnosis of uterine (endometrial) cancer, ovarian cancer and cervical cancer\n* ECOG=0-2\n* Life expectancy of \\> 6 months\n* Completed at least 6 cycles of carboplatin or cisplatin chemotherapy together with paclitaxel at least 3 months before joining the study\n* Able to read and understand the questionnaires\n* PNQ score of C or above\n\nExclusion Criteria:\n\n* Bleeding tendency\n* Abnormal clotting profile\n* Platelet lower than 50\n* Received acupuncture in the past\n* Currently receiving chemotherapy treatment\n* Known neurological disorders or pre-existing neuropathy unrelated to chemotherapy\n* Routinely take aspirin or any anticoagulant drugs\n* Having active skin infection\n* With pacemaker",{"count":150,"type":23},[26],"Objectives:\n\nTo explore the feasibility and effectiveness of acupuncture on reducing Chemotherapy Induced Peripheral Neuropathy (CIPN) in gynaecological cancer patients who have received carboplatin and paclitaxel chemotherapy combination. Results of this pilot trial will provide preliminary information for a potential a larger scale multicentre study.\n\nHypothesis:\n\nAcupuncture can significantly reduce CIPN in gynaecological cancer patients treated with chemotherapy\n\nDesign and subjects:\n\nThis is a pilot, prospective randomised controlled trial. This is an exploratory trial to evaluate the feasibility and effectiveness of acupuncture in reducing CIPN in gynaecological cancer patients. Eligible patients will be 1:1:1 randomised to three groups: electroacupuncture group, sham acupuncture group and waiting-list (usual care) control group. For electroacupuncture and sham acupuncture groups, the assessors and the patients will be blinded to the treatment given.\n\n1. Electroacupuncture group - patients will receive 6 weeks of electroacupuncture, 2 sessions per week, by a qualified Traditional Chinese Medicine practitioner from the School of Chinese Medicine.\n2. Sham acupuncture group - patients will receive 6 weeks of sham acupuncture similar to the above.\n3. Waiting-list (usual care) control group - patients will not receive any treatment.\n\nMain outcomes:\n\nAcupuncture effects will be assessed at baseline and 3, 6,12 weeks post intervention by:\n\n1. Patient reported outcome measures: FACT\u002FGOG-Ntx questionnaire for assessing CIPN symptoms and EORTC-QLQ-C30 and CIPN20 questionnaires for assessing quality of life symptom\n2. Clinician reported outcome measures: NCI-CTCAE grading for CIPN by clinicians and Semmes-Weinstein monofilament test as an objective measurement of CIPN.\n\nData analysis:\n\nIntention to treat analysis will be carried out. Baseline demographics will be compared between the 3 groups. Change from baseline total score will be calculated and analysed using 2-sample t-test. 95% CI will be reported for treatment differences. Score for different subcategories will be analysed in a similar manner. Data collected at week 6 will be used for outcome analysis. P\\\u003C0.05 will be considered as statistically significant. Acupuncture efficacy, effectiveness and placebo effect will be indicated by comparison of acupuncture vs. sham acupuncture, acupuncture vs. waiting-list, and sham acupuncture vs. waiting-list, respectively.\n\nExpected results: Patients in the acupuncture arm will have reduced numbness and peripheral neuropathy and improved quality of life without any adverse event.",[259,260,29],"Gynaecological, Urological or Rectal Cancer","Chemotherapy-Induced Peripheral Neuropathy",[262,29,263],"Gynaecological Cancer","Chemotherapy induced peripheral neuropathy","2026-02-24",{"date":266,"type":44},"2026-02-25",{"date":268,"type":44},"2025-02-12",{"date":270,"type":23},"2027-12",{"name":272,"class":51},"Karen Kar Loen CHAN",{"id":274,"slug":275,"hasResults":12,"nctId":276,"briefTitle":277,"officialTitle":278,"acronym":4,"eligibilityCriteria":279,"healthyVolunteers":12,"sex":280,"minAge":93,"maxAge":281,"enrollmentInfo":282,"targetDuration":4,"studyType":24,"phases":283,"briefSummary":284,"conditions":285,"keywords":4,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":288,"lastUpdatePostDateStruct":289,"startDateStruct":291,"completionDateStruct":293,"leadSponsor":295,"locationsCount":4},"100617863","acupuncture-for-erectile-dysfunction-100617863","NCT07324148","Acupuncture for Erectile Dysfunction","Acupuncture for Erectile Dysfunction Among Patients With Chronic Prostatitis\u002FChronic Pelvic Pain Syndrome: a Clinical Trial","Inclusion Criteria:\n\n* Conforms to the diagnosis of CP\u002FCPPS and pED at the same time;\n* Aged between 18-50 years old;\n* 8≤IIEF-5 score≤21\n* Have a fixed sexual partner and a regular sexual intercourse of ≥1 time\u002Fweek during treatment period;\n* Voluntarily sign an informed consent form.\n\nExclusion Criteria:\n\n* Patients with drug-induced or organic ED.\n* The existence of lesions that may affect erectile function, such as penile cancer, penile sclerosis, penile anatomical deformity, testicular cancer, urinary system stones or neuropathy, etc.\n* History of trauma or surgery in pelvic region.\n* Patients with hypogonadism.\n* Usage of drugs or therapies that relieve CP\u002FCPPS or ED symptoms in the previous 1 month.\n* Have received hormonal or psychiatric drugs in the previous 3 months.\n* Bladder outlet obstruction, overactive bladder, neurogenic bladder, interstitial cystitis, glandular cystitis, sexually transmitted diseases, bladder tumors, prostate cancer, penile cancer, penile stone, other types of prostatitis.\n* With a residual urine ≥100ml.\n* Symptomatic urinary tract infection.\n* Diseases affecting the function of the lower urethra, such as multiple sclerosis, senile dementia, Parkinson's disease, spinal cord injury, caua equina nerve injury, stroke and multisystem atrophy, etc.\n* Severe diseases in heart, lung, brain, liver, kidney and hematopoietic system , mental illness and obvious cognitive function disorders.\n* Patients with poor compliance","MALE","50 Years",{"count":63,"type":23},[26],"Chronic Prostatitis\u002FChronic Pelvic Pain Syndrome (CP\u002FCPPS) is a prevalent chronic urological disease. CP\u002FCPPS severely impacts patients' quality of life. It is characterized by recurrent pelvic floor pain, lower urinary tract symptoms, and often accompanied by psychological issues and sexual dysfunction (duration ≥3 months, no confirmed infection\u002Fpathology).\n\nThe investigators have completed a large-sample, multi-center randomized controlled trial (RCT) involving 440 patients with CP\u002FCPPS before. The clinical trial confirmed the sustained efficacy of acupuncture for the symptoms of pain, lower urinary tract symptoms, and anxiety and depression among patients with CP\u002FCPPS. However, the trial revealed no significant improvements in sexual dysfunction in the acupuncture group compared to the sham acupuncture group after 8 weeks of treatment.To address this limitation, the current study is designed, which aims to optimize the clinical acupuncture protocol for CP\u002FCPPS and evaluate whether it can enhance outcomes for psychogenic erectile dysfunction (ED) associated. Additionally, mass cytometry and liquid suspension chip technology will be used to explore systemic and local immune mechanisms underlying acupuncture's effects for CP\u002FCPPS. Functional magnetic resonance imaging (fMRI) and metabolomics will be integrated to analyze patients' systemic states from central nervous system and metabolic perspectives, comprehensively elucidating the multi-dimensional mechanisms by which acupuncture alleviates CP\u002FCPPS.",[286,287,29],"Chronic Prostatitis\u002FChronic Pelvic Pain Syndrome (CP\u002FCPPS)","Erectile Dysfunctions","2026-01-06",{"date":290,"type":44},"2026-01-08",{"date":292,"type":23},"2026-01-01",{"date":294,"type":23},"2028-06-30",{"name":296,"class":51},"Guang'anmen Hospital of China Academy of Chinese Medical Sciences",{"id":298,"slug":299,"hasResults":12,"nctId":300,"briefTitle":301,"officialTitle":302,"acronym":4,"eligibilityCriteria":303,"healthyVolunteers":12,"sex":92,"minAge":93,"maxAge":4,"enrollmentInfo":304,"targetDuration":4,"studyType":24,"phases":306,"briefSummary":307,"conditions":308,"keywords":310,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":314,"lastUpdatePostDateStruct":315,"startDateStruct":317,"completionDateStruct":319,"leadSponsor":321,"locationsCount":52},"100586066","acu-tens-on-pain-and-stress-reduction-before-and-during-tugor-100586066","NCT06910540","ACU-TENS on Pain and Stress Reduction Before and During TUGOR","Acupuncture-type Transcutaneous Electrical Nerve Stimulation on Pain and Stress Reduction Before and During Transvaginal Ultrasound-guided Oocyte Retrieval: a Randomized Controlled Trial","Inclusion Criteria:\n\n* Women undergoing IVF-ET cycles are to be recruited from the Assisted Reproduction Technology unit in the Prince of Wales Hospital\n\nExclusion Criteria:\n\n* Patient not eligible for acu-TENS\n* Patient with severe cardiac and respiratory disease history\n* Smoker or drinker\n* Refuse or incompetence for informed consent",{"count":305,"type":23},144,[26],"Objectives: To demonstrate the use of acupuncture-type transcutaneous electrical nerve stimulation (acu-TENS) during transvaginal ultrasound-guided oocyte retrieval (TUGOR) will reduce 50% of the intensity of pain experienced by women.\n\nHypothesis to be tested: Does the use of acu-TENS reduce 50% of pain in TUGOR? Design and subjects: A prospective randomized control trial will be carried out at the Department of Obstetrics and Gynaecology, Prince of Wales Hospital. 144 women undergoing TUGOR will be randomized to receive acu-TENS or sham acu-TENS for pain control during TUGOR.\n\nStudy instruments: During the TUGOR procedure, ultrasound of the pelvis will be performed by Aloka ProSound SSD-3500SX device (Japan). Each follicle will be pierced using a single lumen ovum aspiration needle or a double lumen ovum aspiration catheter (COOK Medical, UK) under ultrasound guidance. Acu-TENS will be done using MTR+ Myolito Multifunctional Stimulator.\n\nMain outcome measures: Primary outcome is the pain score before and during TUGOR. Secondary outcomes include (1) other pain level parameters including pain control satisfaction, surgeon's assessment of the patient co-operation score and patient intraoperative pain; (2) stress and anxiety levels, Stait Trait Anxiety Inventory, General Health Questionnaire, Beck Depression Inventory, and saliva cortisol; (3) patient's satisfaction measured by Client Satisfaction Questionnaire and satisfaction score on pain control; (4) difficulty in retrieving oocytes; (5) IVF parameters; (6) safety profile; and (7) bias assessment.\n\nData analysis: Data analysis will be performed using Statistical Packages of Social Sciences for Windows.\n\nExpected results: The investigators expect that acu-TENS will reduce 50% of pain in TUGOR.",[309,29],"Oocyte Retrieival and Post Operative Pain Control",[311,312,313],"Transvaginal ultrasound-guided oocyte retrieval","Acupuncture-type transcutaneous electrical nerve stimulation","Pain control","2025-12-19",{"date":316,"type":44},"2025-12-22",{"date":318,"type":44},"2025-09-01",{"date":320,"type":23},"2028-12-31",{"name":322,"class":51},"Chinese University of Hong Kong",{"id":324,"slug":325,"hasResults":12,"nctId":326,"briefTitle":327,"officialTitle":328,"acronym":4,"eligibilityCriteria":329,"healthyVolunteers":12,"sex":18,"minAge":93,"maxAge":330,"enrollmentInfo":331,"targetDuration":4,"studyType":24,"phases":332,"briefSummary":333,"conditions":334,"keywords":4,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":337,"lastUpdatePostDateStruct":338,"startDateStruct":340,"completionDateStruct":342,"leadSponsor":344,"locationsCount":4},"100611278","acupuncture-for-post-hemorrhoidectomy-pain-control-100611278","NCT07238504","Acupuncture for Post-hemorrhoidectomy Pain Control","Acupuncture for Post-hemorrhoidectomy Pain Control With Acute Anti-inflammatory Effects: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Symptomatic grade III or IV hemorrhoids undergoing conventional hemorrhoidectomy\n\nExclusion Criteria:\n\n1. Patients scheduled for stapled hemorrhoidopexy\n2. Concomitant surgery other than conventional hemorrhoidectomy\n3. Bleeding tendency, thrombocytopenia (platelet count \\\u003C 100 x 10\\^9\u002FL)\n4. Immunocompromised status or use of chemotherapy\n5. Active dermatitis\n6. Patients with pacemaker or automated implantable cardioverter-defibrillator\n7. Pregnant patients\n8. Known allergy to opioids, local anaesthetic drugs, paracetamol, non-steroidal anti-inflammatory drugs (NSAIDS) including cyclooxygenase-2 inhibitors\n9. History of chronic pain (duration for 3 months or more)\n10. Daily use of strong opioids (e.g. morphine, fentanyl, hydromorphone, methadone, oxycodone, or meperidine)\n11. Alcohol or drug abuse\n12. Psychiatric illness\n13. Impaired renal function (preoperative serum creatinine level \\> 120µmol\u002FL)\n14. Recent acupuncture treatment for other medical conditions","90 Years",{"count":63,"type":23},[26],"The goal of this clinical trial is to learn if acupuncture improves pain control after hemorrhoidectomy in patients with symptomatic hemorrhoids. It will also learn about the safety of using acupuncture in surgical patients. The main questions it aims to answer are:\n\nDoes acupuncture lower the maximal pain intensity after hemorrhoidectomy? Does acupuncture reduce analgesics requirement, length of hospital stay and quality of recovery?\n\nResearchers will compare fully active acupuncture to a sham treatment (a look-alike procedure with minimum acupuncture stimulation) to see if active acupuncture works to improve pain control.\n\nParticipants will:\n\nReceive acupuncture treatment for 7 times over first 5 days after surgery. Visit the clinic once 2 weeks after surgery for checkups and tests. Keep a diary of their symptoms and the number of times they take pain-killers.",[335,336,29],"Hemorrhoidectomy","Hemorrhoid Pain","2025-11-24",{"date":339,"type":44},"2025-12-02",{"date":341,"type":23},"2026-03",{"date":343,"type":23},"2027-04",{"name":345,"class":51},"The University of Hong Kong",{"id":347,"slug":348,"hasResults":12,"nctId":349,"briefTitle":350,"officialTitle":351,"acronym":4,"eligibilityCriteria":352,"healthyVolunteers":12,"sex":18,"minAge":353,"maxAge":201,"enrollmentInfo":354,"targetDuration":4,"studyType":24,"phases":355,"briefSummary":356,"conditions":357,"keywords":365,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":367,"lastUpdatePostDateStruct":368,"startDateStruct":370,"completionDateStruct":372,"leadSponsor":374,"locationsCount":52},"100571845","integrative-medicine-in-pain-management-in-sickle-cell-disease-20-100571845","NCT06725550","Integrative Medicine in Pain Management in Sickle Cell Disease, 2.0","Integrative Medicine in Pain Management in Sickle Cell Disease: Assessing the Clinical Efficacy and Neurobiological Impact With Acupuncture, 2.0","Inclusion Criteria:\n\n* Any gender\n* 14-17 (Adolescents) and 18-80 (Adults) years old\n* Right-handed\n* Either outpatient or inpatient or status changing between each other\n* Have been diagnosed with SCD (includes but not limited to SS, SC or other type) and experiencing chronic pain in the past 6 months or vaso-occlusive crisis (VOC) in the past 12 months.\n* Analgesic therapy prescribed by primary hematologists (or physicians for emergency or primary care) including pain-relieving medications (e.g. Morphine, coderin, Fentanyl, Oxycodone), Hydroxyurea (e.g. Droxia, Hydrea, Siklos), L-glutamine oral powder (Endari), Crizanlizumab (Adakveo), Voxelotor (Oxbryta), and\u002For other palliative treatment allowed, not required.\n* Willing to limit the current and the introduction of any new medications or treatment modalities for control of pain symptoms during the study visits.\n* Able to travel to the study site for participating scheduled visits (questionnaires, QST, EEG and MRI) and receive acupuncture treatments up to two times weekly for 5 weeks as scheduled.\n* We will recruit without regard to ethnicity, however, due to the genetic nature of SCD, subjects will primarily be African-American or of African descent, although there are individuals with SCD who come from Hispanic, southern European, Middle Eastern, or Asian Indian backgrounds. The ethnic distribution in our prior studies is 95% Black\u002FAfrican American with 5% Hispanic or Latino (of any race). As these are minority groups many individuals may be from lower income situations.\n* Fluent in English and capable of giving written informed consent.\n\nExclusion Criteria:\n\n* Subjects with Covid-19 suspicion or confirmation\n* Recent\u002Fongoing alternative pain management with acupuncture or acupuncture-related techniques within the last 6-months.\n* Presence of a known coagulation abnormality: Thrombocytopenia (mild thrombocytopenia with a platelets range of 51,000-100,000\u002Ful will be further evaluated for inclusion consideration), or bleeding diathesis that may preclude the safe use of acupuncture.\n* Presence of a concurrent autoimmune or inflammatory disease such as rheumatoid arthritis, systemic lupus erythematosus, inflammatory bowel disease, etc. that causes pain or any other chronic pain condition with pain greater than sickle pain.\n* Diseases\u002Fconditions history includes but not limited to:\n\n  * head injury with substantial loss of consciousness\n  * peripheral neuropathy of known cause that interferes with activities of daily living\n  * known non-SCD related Severe psychiatric illnesses (e.g. current schizophrenia, major depression with suicidal ideation).\n  * significant visual, motor, or auditory impairment that would interfere with ability to perform study visits-related activities\n* Medication:\n\nRecent (30 days) initiation or dose adjustment of stimulant medications, such as those used to treat ADD\u002FADHD (e.g., amphetamine\u002Fdextroamphetamine \\[Adderall®\\], methylphenidate, dextroamphetamine), or the fatigue associated with sleep apnea or shift work (e.g., modafinil).\n\n* Contraindications to MRI scans includes but are not limited to: surgical clips, surgical staples, metal implants, cardiac rhythmic disorders, seizure disorders, and certain metallic dental material will not be scheduled for MRI visits.\n* History vascular surgery in lower limbs or current lower limb vascular dysfunction will not receive conditioned pressure pain stimuli in the lower limb.\n* Subjects with Worker's Compensation, Workman's Compensation, civil litigation or disability claims pertinent to the subject's sickle disease; current involvement in out-of-court settlements for claims pertinent to the subject's sickle disease; or currently receiving monetary compensation as a result of any of the above.\n* Participation of other studies: Concurrent participation in other therapeutic trials with overlapping research purposes.\n* Pregnant or nursing.","14 Years",{"count":22,"type":23},[26],"The proposed research is to determine the clinical efficacy and neurobiological mechanisms of acupuncture analgesia in patients with sickle cell disease.",[358,359,29,360,361,362,363,364],"Sickle Cell Disease","Pain","Quantitative Sensory Testing","Magnetic Resonance Imaging","Circulating Biomarkers","Electroencephalography","Functional Near-infrared Spectroscopy",[366,359,29,360,361,362,363,364],"Sickle cell disease","2025-10-15",{"date":369,"type":44},"2025-10-20",{"date":371,"type":44},"2025-08-25",{"date":373,"type":23},"2030-08-30",{"name":375,"class":51},"Indiana University",{"id":377,"slug":378,"hasResults":12,"nctId":379,"briefTitle":380,"officialTitle":381,"acronym":4,"eligibilityCriteria":382,"healthyVolunteers":173,"sex":92,"minAge":93,"maxAge":383,"enrollmentInfo":384,"targetDuration":4,"studyType":24,"phases":386,"briefSummary":387,"conditions":388,"keywords":4,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":390,"lastUpdatePostDateStruct":391,"startDateStruct":393,"completionDateStruct":395,"leadSponsor":397,"locationsCount":52},"100607073","acupuncture-for-anxietydepression-in-patients-with-breast-cancer-100607073","NCT07183813","Acupuncture for Anxiety\u002FDepression in Patients With Breast Cancer","Effects of Acupuncture for Anxiety and\u002For Depression Among Patients With Breast Cancer","Inclusion Criteria:\n\n1. Female, aged 18 to 70 years old;\n2. Meeting the diagnostic criteria for breast cancer and at TMN I-III;\n3. Having completed specialized active treatment for at least one month;\n4. With an ECOG score of 0-2;\n5. Mild to moderate anxiety and\u002For depression;\n6. Voluntarily joining this study and signing the informed consent form.\n\nExclusion Criteria:\n\n1. Starting to take or change the regimen of anti-anxiety and\u002For -depression disorder medication within one month before enrolment;\n2. Received psychological intervention or physical therapy one month before enrolment or planning to use in the next 5 months;\n3. With diagnosis of anxiety and\u002For depression disorder prior to the diagnosis of breast cancer;\n4. Patients with suicidal tendencies, bipolar disorder and psychotic symptoms;\n5. Patients with severe anxiety and\u002For depression；\n6. Patients received acupuncture treatment within one month before enrolment;\n7. Participating in other clinical studies on the treatment of anxiety and\u002For depression;\n8. Combined with severe underlying diseases;\n9. Patients with severe skin ulcers;\n10. Pregnant or lactating patients;\n11. Poor compliance.","70 Years",{"count":385,"type":23},360,[26],"The aim of this study is to evaluate the effects and safety of acupuncture on anxiety and\u002For depression among patients with breast cancer.",[389,99,29],"Anxiety Depression","2025-09-19",{"date":392,"type":44},"2025-09-24",{"date":394,"type":23},"2025-09-15",{"date":396,"type":23},"2026-12-30",{"name":296,"class":51},{"id":399,"slug":400,"hasResults":12,"nctId":401,"briefTitle":402,"officialTitle":403,"acronym":4,"eligibilityCriteria":404,"healthyVolunteers":12,"sex":18,"minAge":93,"maxAge":405,"enrollmentInfo":406,"targetDuration":4,"studyType":24,"phases":407,"briefSummary":408,"conditions":409,"keywords":412,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":394,"lastUpdatePostDateStruct":415,"startDateStruct":416,"completionDateStruct":418,"leadSponsor":420,"locationsCount":52},"100478967","determining-the-right-acupuncture-for-good-recovery-over-neuropsychiatric-trauma-100478967","NCT05516862","Determining the Right Acupuncture for Good Recovery Over Neuropsychiatric Trauma","Determining the Right Acupuncture for Good Recovery Over Neuropsychiatric Trauma (DRAGON)","Inclusion Criteria:\n\n* Active Duty members and DoD beneficiaries(i.e. former military, spouse, dependent child), 18-65 years old\n* Meeting the criteria for PTSD based on PCL-5 (past month scores) score of 31 or higher\n* At least 1 positive response to at least one item on the LEC-5.\n\nExclusion Criteria:\n\n* Pregnant, may be pregnant, or attempting to become pregnant. There areno known risks of this acupuncture in pregnant patients; however, we will exclude pregnancy due to the location of the needles (right over the uterus in 3rd trimester) and risk of exacerbating anxiety that may cause stress on the baby. Subjects will be told to let us know if they become pregnant so we can disenroll them from the study.\n* Prior treatment with Dragons acupuncture\n* History of hospitalization for mental health reasons within the last year\n* Active Suicidal thoughts (is currently considering suicide or has a plan) or suicide attempt within the last year. This will be assessed by direct questioning.\n* Is currently receiving acupuncture or other non-medication treatments specifically for PTSD (patients can elect to forgo PTSD treatments during the study period and then resume after the study period is over; ie halt therapy during the study period)\n* Legally Authorized Representatives will not be utilized in this study\n\n\\*\\*Patients must be able to get care at Nellis Air Force Base (a military installation) in order to participate in this study\\*\\*","74 Years",{"count":150,"type":23},[26],"This study seeks to verify that a specific acupuncture treatment is effective at reducing symptoms of neuropsychiatric trauma found in those diagnosed with Post-Traumatic Stress Disorder (PTSD).",[410,411,29],"PTSD","Post Traumatic Stress Disorder",[410,413,414],"DRAGONS","family medicine residency",{"date":390,"type":44},{"date":417,"type":44},"2022-10-01",{"date":419,"type":23},"2026-10-01",{"name":421,"class":140},"Paul Crawford",{"id":423,"slug":424,"hasResults":12,"nctId":425,"briefTitle":426,"officialTitle":427,"acronym":428,"eligibilityCriteria":429,"healthyVolunteers":12,"sex":18,"minAge":93,"maxAge":4,"enrollmentInfo":430,"targetDuration":4,"studyType":24,"phases":432,"briefSummary":433,"conditions":434,"keywords":443,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":446,"lastUpdatePostDateStruct":447,"startDateStruct":449,"completionDateStruct":451,"leadSponsor":452,"locationsCount":52},"100602461","acuknee-role-of-acupuncture-in-knee-prosthetic-surgery-100602461","NCT07123805","ACU_Knee: Role of Acupuncture in Knee Prosthetic Surgery","ACU_Knee - Role of Acupuncture in Knee Prosthetic Surgery: Analgesia, Functional Outcome and Inflammatory Markers","ACU_Knee","Inclusion Criteria:\n\n* Patients aged \\> 18 years\n* Patients capable of providing informed consent\n* Unilateral total knee replacement surgery\n* Indication for surgery: primary osteoarthritis degeneration\n* Surgery performed electively\n\nExclusion Criteria:\n\n* Patients aged \\\u003C 18 years\n* Patients incapable of providing informed consent\n* Patients with ASA class \\> 3\n* Pregnant women\n* Patients with rheumatoid arthritis or other autoimmune disorders\n* Patients with active infection under antibiotic treatment\n* Patients on chronic opioid therapy\n* Patients on chronic biological drug therapy\n* Patients with a history of corticosteroid use in the six months prior to surgery\n* Patients with a history of periarticular infiltration in the three months prior to surgery\n* Patients in whom loco-regional anesthesia is contraindicated\n* Patients in whom NSAID, cortisone, and paracetamol therapy is contraindicated\n* Bilateral total knee replacement surgery or prosthetic revision surgeries\n* Indication for surgery for causes other than primary osteoarthritis degeneration",{"count":431,"type":23},80,[26],"Post-operative analgesia after total knee arthroplasty (TKA) has always been a challenge in the anesthesiological setting, having to combine good pain control and the need for early mobilization, both factors that can affect the quality of rehabilitation treatment, prosthetic functional outcome, the onset of chronic pain, joint stiffness and the consequent quality of life of the patient. Recent loco-regional anesthesia (LRA) techniques have made an essential contribution to peri-operative management in the fast-track perspective of surgery, in terms of optimization of analgesia and rapid functional recovery. Inadequate post-operative analgesia, by affecting the normal rehabilitation pathway, is associated with medium-long term complications, such as chronic pain, joint stiffness and patient dissatisfaction, which often compromise functional autonomy and quality of life of the patient and may require invasive treatments (surgical revision, unlocking under general anesthesia). The local and systemic inflammatory state, evidenced by peri-operative dosage of specific biomarkers, appears to be related to prosthetic outcome.",[435,29,436,437,438,439,440,441,442],"Acupuncture Analgesia","Acupuncture Therapy","Total Knee Anthroplasty","Postoperative Pain Management","Pain Threshold","Shoulder Pain","Laparoscopies","Acupuncture Ear",[130,444,445],"total knee arthroplasty","pain","2025-08-08",{"date":448,"type":44},"2025-08-14",{"date":450,"type":44},"2024-04-10",{"date":189,"type":23},{"name":453,"class":51},"Fondazione IRCCS Policlinico San Matteo di Pavia",{"id":455,"slug":456,"hasResults":12,"nctId":457,"briefTitle":458,"officialTitle":458,"acronym":4,"eligibilityCriteria":459,"healthyVolunteers":12,"sex":18,"minAge":460,"maxAge":461,"enrollmentInfo":462,"targetDuration":4,"studyType":24,"phases":464,"briefSummary":465,"conditions":466,"keywords":4,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":469,"lastUpdatePostDateStruct":470,"startDateStruct":472,"completionDateStruct":474,"leadSponsor":476,"locationsCount":52},"100595741","acupuncture-versus-transcutaneous-electrical-nerve-stimulation-on-pain-post-upper-abdominal-surgeries-100595741","NCT07036393","Acupuncture Versus Transcutaneous Electrical Nerve Stimulation on Pain Post Upper Abdominal Surgeries","Inclusion Criteria:\n\n* Patients who will have pain after upper abdominal surgery.\n* Adult patients will be between 20 and 45 years of age.\n* Both sexes will be included.\n* Patients have no contraindications for acupuncture or transcutaneous electrical nerve stimulation.\n* Patients with good compliance and fit for treatment.\n* This study will be applied on upper abdominal surgeries \\[laparoscopic cholecystectomy, Gastrectomy\\].\n* Physical therapy will be used for up to 48 hours after surgery or until the time of discharge.\n\nExclusion Criteria:\n\n* Patients with other causes of pain other than that after upper abdominal surgery.\n* Patients who will have any contraindication for both therapies used.\n* Patients with cardiovascular disease, liver, or renal disease.\n* Patients with malignant tumors.\n* Patients with metal or electronic implants.\n* Patients with autoimmune disease.\n* Pregnancy, postpartum period, breastfeeding.\n* Patients with recent injury in the treatment area","20 Years","45 Years",{"count":463,"type":23},40,[26],"This study was done to:\n\n* Determine the therapeutic efficacy of acupuncture as physical therapy approach in minimizing pain post upper abdominal surgeries.\n* Determine the therapeutic efficacy of transcutaneous electrical nerve stimulation in minimizing pain post upper abdominal surgeries.\n* Compare the efficacy and safety of Transcutaneous electrical nerve stimulation versus acupuncture in minimizing pain post upper abdominal surgeries.",[29,467,359,468],"Transcutaneous Electrical Nerve Stimulation","Upper Abdominal Surgery","2025-06-24",{"date":471,"type":44},"2025-06-25",{"date":473,"type":44},"2025-04-15",{"date":475,"type":23},"2025-07-15",{"name":477,"class":51},"Cairo University",{"id":479,"slug":480,"hasResults":12,"nctId":481,"briefTitle":482,"officialTitle":483,"acronym":484,"eligibilityCriteria":485,"healthyVolunteers":12,"sex":18,"minAge":486,"maxAge":61,"enrollmentInfo":487,"targetDuration":4,"studyType":24,"phases":489,"briefSummary":492,"conditions":493,"keywords":496,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":506,"lastUpdatePostDateStruct":507,"startDateStruct":509,"completionDateStruct":511,"leadSponsor":512,"locationsCount":4},"100591617","phase-1-acupuncture-versus-compound-diclofenac-sodium-for-pain-relief-in-non-traumatic-acute-abdominal-100591617","NCT06982755","Acupuncture Versus Compound Diclofenac Sodium for Pain Relief in Non-Traumatic Acute Abdominal","Effect of Acupuncture on Early Analgesia of Non-traumatic Acute Abdomen is Discussed Based on the Experience of Sanli Acupoint for Du-fu Diseases :A Prospective Randomized Controlled pRCT Study","ACU-NTAA","Inclusion Criteria:\n\n1. The diagnostic criteria of NTAA were as follows: ① abdominal pain was the main symptom; ② The onset time was less than 1 week; ③ The cause of abdominal pain could be traced to intra-abdominal abdominal wall chest or systemic diseases;\n2. Patients with NRS scores ≥4 (mild pain and above) were evaluated before inclusion; （3）16 years \\\u003C age \\\u003C75 years;\n\n（4）Those who were considered not to need surgery within 2 hours after initial assessment by a specialist.\n\nExclusion Criteria:\n\nParticipants meeting any of the following criteria were excluded from the study:\n\n1. Acute abdomen caused by trauma;\n2. Super sudden diseases (e.g. acute myocardial infarction rupture of abdominal aortic aneurysm pulmonary embolism aortic dissection pericardial tamponade);\n3. Emergent conditions requiring surgical treatment within 3 hours (e.g. rupture of liver cancer ectopic pregnancy ischemic bowel disease severe acute cholangitis peritonitis with septic shock);\n4. Extremely severe pain (NRS ≥ 8) with an undetermined diagnosis and requiring further assessment for a super sudden disease;\n5. Inability to select acupuncture points due to skin injury or ulceration at Zusanli (ST36) on the lower limb;\n6. Induration or infection at the hip injection site;\n7. Patients with altered consciousness mental illness other severe chronic diseases or those who are unlikely to cooperate with acupuncture treatment;\n8. Contraindications to Western medicine:\n\n   * Known allergies to diclofenac sodium or acetaminophen; ②History of asthma urticaria or allergic reactions induced by aspirin or other NSAIDs.\n\n     * Undergoing coronary artery bypass grafting (CABG) surgery. ④History of gastrointestinal bleeding or perforation following non-steroidal anti-inflammatory drugs (NSAIDs).\n\n       * Active gastrointestinal ulcers or bleeding or a history of recurrent ulcers or bleeding.\n\n         * Severe heart failure.\n9. Use of any pain medication or acupuncture within the past 6 hours;\n10. Previous participation in this study;\n11. Pregnant or lactating individuals.","16 Years",{"count":488,"type":23},176,[490,491],"PHASE1","PHASE2","The investigators designed this clinical study to evaluate the efficacy and safety of semi-standardized acupuncture and moxibustion combined with compound diclofenac sodium injection in the emergency department (ED) compared with acupuncture or compound diclofenac sodium injection alone.",[494,436,29,495],"Acute Abdominal Pain","Opioids",[497,498,499,500,29,501,502,503,495,504,505],"Acute abdominal pain","Non-Traumatic Acute Abdomen","Non-traumatic acute abdomen early analgesia","Acupuncture therapy","Zusanli point, ST36","Diclofenac sodium","Emergency environment","Non-steroidal anti-inflammatory drugs ，NSAIDs","Acetaminophen","2025-05-20",{"date":508,"type":44},"2025-05-21",{"date":510,"type":23},"2025-06-01",{"date":189,"type":23},{"name":513,"class":51},"The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine",{"id":515,"slug":516,"hasResults":12,"nctId":517,"briefTitle":518,"officialTitle":519,"acronym":4,"eligibilityCriteria":520,"healthyVolunteers":12,"sex":92,"minAge":93,"maxAge":521,"enrollmentInfo":522,"targetDuration":4,"studyType":24,"phases":524,"briefSummary":525,"conditions":526,"keywords":529,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":531,"lastUpdatePostDateStruct":532,"startDateStruct":533,"completionDateStruct":535,"leadSponsor":536,"locationsCount":246},"100540418","clinical-study-on-dry-needling-for-primary-dysmenorrhea-and-its-preliminary-correlation-with-acupoints-100540418","NCT06316583","Clinical Study on Dry Needling for Primary Dysmenorrhea and Its Preliminary Correlation With Acupoints","Clinical Study of Dry Needling on Myofascial Trigger Points Treatment for Primary Dysmenorrhea and Preliminary Investigation of Its Relevance to Acupoints","Inclusion Criteria:\n\n1. All participants diagnosed explicitly by a gynecologist as having primary dysmenorrhea without pelvic organic lesions.\n2. Aged between 18 and 30 years.\n3. A history of cyclical menstrual pain for more than 2 years.\n4. Pain greater than 30mm on the Visual Analog Scale (VAS, 0-100mm).\n5. Participants must sign an informed consent form and be willing to undergo acupuncture treatment and cooperate to complete the relevant procedures of this trial.\n\nExclusion Criteria:\n\n1. Those suffering from secondary dysmenorrhea or any other reproductive and urinary system diseases, such as endometriosis.\n2. A history of pregnancy, miscarriage, or planning for pregnancy. Individuals with skin infections on the abdomen and lower back.\n3. Past use of acupuncture therapy or other needling treatments.\n4. Those with a history of mental illness and severe diseases of the heart, liver, brain, kidneys, hematopoietic system, etc.\n5. Within the past 6 months, individuals referred to pain clinics, those who have used pain relievers like morphine or pethidine, or those allergic to NSAIDs. Also, those currently taking or receiving anticoagulant medications.\n6. Individuals who have had adverse reactions to acupuncture (e.g., fainting).","30 Years",{"count":523,"type":23},150,[26],"Primary dysmenorrhea refers to menstrual pain not caused by pelvic organic lesions, commonly seen in young women, significantly affecting patients' quality of life. Dry needling therapy targeting myofascial trigger points for primary dysmenorrhea has been preliminarily applied in clinical settings. However, related research is limited with questionable quality, hindering its widespread clinical application. Furthermore, is there a connection between myofascial trigger points in dry needling and acupuncture acupoints in terms of selection and mechanism of action? Could this be a new interpretation of acupuncture theory? These are important questions that have garnered widespread attention. This study employs a randomized patient-blinded controlled design, enrolling primary dysmenorrhea patients aged 18 to 30 years. They are randomly divided into three groups: the trigger point dry needling group, traditional acupuncture treatment group, and trigger point sham needle (placebo) group. Changes in pain levels, quality of life scores, inflammatory factor levels, and local blood flow before and after treatment among the three groups are observed. The aim is to assess the therapeutic effects of dry needling trigger points and acupuncture treatments on primary dysmenorrhea and explore their potential mechanisms of action. By comparing the differences and similarities between dry needling trigger points and acupuncture treatments in terms of acupoint selection, treatment effects, and potential mechanisms of action, this study seeks to preliminarily explore the feasibility of integrating trigger point theory into the meridian 'acupoint' theory, laying the foundation for a modern interpretation of acupuncture",[527,29,528],"Trigger Point Pain, Myofascial","Primary Dysmenorrhea",[530],"trigger points, dry-needling, primary dysmenorrhea","2025-05-17",{"date":508,"type":44},{"date":534,"type":44},"2024-04-01",{"date":189,"type":23},{"name":537,"class":538},"Beijing Hospital","OTHER_GOV",{"id":540,"slug":541,"hasResults":12,"nctId":542,"briefTitle":543,"officialTitle":543,"acronym":4,"eligibilityCriteria":544,"healthyVolunteers":12,"sex":18,"minAge":93,"maxAge":4,"enrollmentInfo":545,"targetDuration":4,"studyType":24,"phases":547,"briefSummary":548,"conditions":549,"keywords":551,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":553,"lastUpdatePostDateStruct":554,"startDateStruct":556,"completionDateStruct":558,"leadSponsor":560,"locationsCount":52},"100588277","efficacy-of-acupuncture-for-shoulder-pain-based-on-remote-point-selection-according-to-the-meridians-100588277","NCT06939309","Efficacy of Acupuncture for Shoulder Pain Based on Remote Point Selection According to the Meridians","Inclusion Criteria:\n\n* Participants must be at least 18 years old.\n* Shoulder pain persisting for at least one week.\n* Numerical Rating Scale (NRS) score ≥ 4.\n\nExclusion Criteria:\n\n* Patients with cervical radiculopathy or other localized neurological disorders affecting the upper limb.\n* Psychiatric disorders that may interfere with examination, treatment, or evaluation of disease progression.\n* Pregnant patients.\n* Inability to provide informed consent.",{"count":546,"type":23},90,[26],"This double blind randomized controlled trial investigates the immediate efficacy of acupuncture for shoulder pain using remote point selection based on meridian theory. A total of 90 participants with shoulder pain (Numerical Rating Scale ≥ 4) will be randomly assigned in a 1:1:1 ratio to one of three groups: acupuncture SC, acupuncture CS, and rehabilitation. Meridian selection will be determined based on the patient's most painful shoulder movement and corresponding pain location, followed by standardized distal acupoint application. Outcome measures include changes in pain intensity (NRS) and shoulder range of motion assessed at baseline, post-first acupuncture, post-second acupuncture, and 30 minutes post-treatment. Blinded evaluators will conduct all assessments. The study aims to assess the effectiveness of meridian-based remote acupuncture and explore its relationship with shoulder movement patterns and soft tissue involvement.",[440,29,550],"Meridians",[552,29,550],"Shoulder pain","2025-04-22",{"date":555,"type":44},"2025-04-24",{"date":557,"type":23},"2025-04-18",{"date":559,"type":23},"2026-06-30",{"name":561,"class":51},"China Medical University Hospital",{"id":563,"slug":564,"hasResults":12,"nctId":565,"briefTitle":566,"officialTitle":566,"acronym":4,"eligibilityCriteria":567,"healthyVolunteers":12,"sex":18,"minAge":93,"maxAge":568,"enrollmentInfo":569,"targetDuration":4,"studyType":571,"phases":4,"briefSummary":572,"conditions":573,"keywords":4,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":576,"lastUpdatePostDateStruct":577,"startDateStruct":579,"completionDateStruct":581,"leadSponsor":583,"locationsCount":246},"100574264","a-clinical-follow-up-study-on-the-efficacy-of-thumbtack-needle-for-postoperative-sleep-and-recovery-treatment-100574264","NCT06757023","A Clinical Follow-up Study on the Efficacy of Thumbtack Needle for Postoperative Sleep and Recovery Treatment","Inclusion Criteria:\n\n1. Patients undergoing breast cancer surgery with general anesthesia in the hospital;\n2. American Society of Anesthesiologists (ASA) classification I-II;\n3. Women aged 18-55 years;\n4. No history of chronic insomnia;\n5. Individuals who have not taken sedative-hypnotic drugs within the past month.\n\nExclusion Criteria:\n\n1. Those who do not meet the aforementioned inclusion criteria;\n2. A history of severe heart, brain, lung, or kidney diseases (such as acute coronary syndrome (ACS), severe heart failure classified as NYHA Class III or IV, severe arrhythmias, severe valvular disease; acute aortic disease, and severe peripheral vascular disease, etc.), or poor physical condition (including reduced exercise tolerance, multi-organ dysfunction, malnutrition, etc.);\n3. A history of sleep disorders and psychiatric history;\n4. Inability to receive thumb-tack needle treatment.","55 Years",{"count":570,"type":23},110,"OBSERVATIONAL","To understand the impact of thumb-tack needle therapy on postoperative sleep and recovery in patients who have undergone general anesthesia, and to explore the clinical significance of thumb-tack needle therapy in improving postoperative sleep quality, preventing postoperative sleep disorders, and promoting postoperative recovery",[574,575,29],"Postoperative Complications","Postoperative Pain","2024-12-25",{"date":578,"type":44},"2025-01-03",{"date":580,"type":44},"2024-11-13",{"date":582,"type":23},"2026-11-13",{"name":584,"class":51},"The First Affiliated Hospital of Xiamen University",{"id":586,"slug":587,"hasResults":12,"nctId":588,"briefTitle":589,"officialTitle":590,"acronym":4,"eligibilityCriteria":591,"healthyVolunteers":12,"sex":92,"minAge":93,"maxAge":60,"enrollmentInfo":592,"targetDuration":4,"studyType":24,"phases":594,"briefSummary":595,"conditions":596,"keywords":4,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":599,"lastUpdatePostDateStruct":600,"startDateStruct":602,"completionDateStruct":604,"leadSponsor":606,"locationsCount":52},"100571195","study-of-acupuncture-to-control-weight-and-improve-pregnancy-rates-in-overweightobese-pcos-patients-100571195","NCT06717087","Study of Acupuncture to Control Weight and Improve Pregnancy Rates in Overweight\u002FObese PCOS Patients","A Randomized Controlled Study of Acupuncture to Control Weight and Improve Pregnancy Rates in Overweight\u002FObese Polycystic Ovary Syndrome Patients","Inclusion Criteria:\n\n1. Diagnosis of PCOS according to the 2003 Rotterdam criteria with at least two of the following three symptoms: clinical and\u002For biochemical signs of hyperandrogenism (hirsutism or acne), oligomerism\u002Famenorrhea, and\u002For polycystic ovaries (PCOS). Biochemical hyperandrogenism is defined as total testosterone \\> 2.6 nmol\u002FL or free androgen index \\>7. Hirsutism is defined as an FG score ≥7. Oligomenorrhea is defined as menstrual bleeding \\> 35 days between menstrual periods in the past year, \\\u003C 8 menstrual bleeding. Amenorrhea is \\\u003C 3 cycles per year. PCO is defined by transvaginal ultrasound, where one or both ovaries ≥ 12 follicles 2-9 mm and\u002For ovarian volume ≥ 10 mL. Other endocrine disorders such as atypical congenital adrenal hyperplasia (17-hydroxyprogesterone \\\u003C3 nmol\u002FL), androgen-secreting tumors, or suspected Cushing syndrome are excluded.\n2. Age from ≥ 20 years old (legal age of marriage) to ≤ 40 years old\n3. PCOS patients: BMI ≥ 25 to ≤40kg\u002Fm2.\n4. Willing to sign the consent form.\n\nExclusion Criteria:\n\n1. History of severe heart disease, hematologic disease;\n2. Known kidney disease (creatinine clearance rate \\\u003C45mL\u002Fmin), liver function ALT, AST more than 3 times the normal value, autoimmune disease or cancer;\n3. Any acute disease that has the potential to alter renal function or cause tissue hypoxia;\n4. Type I diabetes mellitus;\n5. Medication within 12 weeks (hormonal drugs, antidepressants, other anti-diabetic drugs, contraceptives, ovulation induction drugs or other drugs that affect the trial in the judgment of the investigator);\n6. Allergy to metformin hydrochloride or any excipients;\n7. Blood pressure \\> 160\u002F100 mm Hg;\n8. Pregnancy or breastfeeding in the past three months;\n9. No history of acupuncture treatment within 2 months;\n10. Alcohol dependence\n11. Persons with disabilities with language impairment or reduced ability to understand the information provided;\n12. Those who have participated in other clinical studies within three months;\n13. The man clearly diagnoses infertility-related diseases and factors.",{"count":593,"type":23},92,[26],"Polycystic ovary syndrome (PCOS) is the most common cause of anovulatory infertility and is characterized by ovulatory dysfunction, increased androgens, and polycystic ovaries. The goal of this randomized control study is to compare the efficacy between acupuncture and metformin both with intensive lifestyle intervention for overweight \u002Fobese PCOS patients in weight and pregnancy rates improvement.",[597,598,29],"Polycystic Ovary Syndrome","Metformin","2024-11-29",{"date":601,"type":44},"2024-12-04",{"date":603,"type":23},"2024-12-20",{"date":605,"type":23},"2026-06-01",{"name":607,"class":51},"RenJi Hospital",{"id":609,"slug":610,"hasResults":12,"nctId":611,"briefTitle":612,"officialTitle":613,"acronym":4,"eligibilityCriteria":614,"healthyVolunteers":12,"sex":18,"minAge":93,"maxAge":201,"enrollmentInfo":615,"targetDuration":4,"studyType":24,"phases":617,"briefSummary":618,"conditions":619,"keywords":4,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":622,"lastUpdatePostDateStruct":623,"startDateStruct":624,"completionDateStruct":626,"leadSponsor":628,"locationsCount":52},"100564783","acupuncture-for-post-covid-19-condition-long-covid-neuropsychiatric-symptoms-100564783","NCT06633666","Acupuncture for Post COVID-19 Condition (Long COVID) Neuropsychiatric Symptoms","Acupuncture for Long COVID Neuropsychiatric Symptoms: a Pragmatic,Randomized Clinical Trial","Inclusion Criteria:\n\n* meet the clinical diagnosis of Long COVID by the World Health Organization (WHO), with no neuropsychiatric symptoms 1 year before infection with Covid-19, and continue to have at least one neuropsychiatric symptom for 2 months after SARS-CoV-2 turned negative 3 months above;\n* aged 12 to 80 years;\n* willing and able to consent, and complete all assessment and study procedures\n\nExclusion Criteria:\n\n* patients with a history of chronic neuropsychiatric symptoms;\n* cardiovascular diseases pre-existing to the Covid-19 episode such as arrhythmia, heart failure, myocardial infarction, and patients with cardiac pacemakers;\n* documented pre-existing history of psychiatric illness, including substance abuse;\n* suicidal tendencies (attempted suicide in the 12 months before the study);\n* any chronic or remote neurological disorder (i.e. stroke, head trauma, epilepsy, tumor);\n* those who participated in other clinical trials within one month;\n* pregnant or lactating female patients;\n* have surgery within two months before the study or will have a scheduled surgery during the study;\n* acute brain injury or acute encephalopathy from another etiology than Covid-19 (e.g., sepsis, liver or renal failure, alcohol or drug withdrawal, drug toxicity);\n* open-heart cardiac surgery or cardiac arrest during the last 6 months;\n* patients who received acupuncture treatment 1 month before the start of the study;\n* patients who were unable to complete the assessment during screening due to severe mental, cognitive, or emotional impairment",{"count":616,"type":23},160,[26],"In this study, a 12-week pragmatic, randomized, double-blinded clinical trial will be conducted to evaluate the efficacy of acupuncture for the treatment of long Covid neuropsychiatric symptoms and provide reference for clinical non-drug treatment.",[620,621,29],"Long Covid19","Neuropsychiatric Symptom","2024-11-11",{"date":580,"type":44},{"date":625,"type":44},"2023-07-30",{"date":627,"type":23},"2026-04-30",{"name":629,"class":51},"Hong Kong Baptist University",{"id":631,"slug":632,"hasResults":12,"nctId":633,"briefTitle":634,"officialTitle":635,"acronym":4,"eligibilityCriteria":636,"healthyVolunteers":173,"sex":18,"minAge":460,"maxAge":330,"enrollmentInfo":637,"targetDuration":4,"studyType":24,"phases":639,"briefSummary":640,"conditions":641,"keywords":643,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":648,"lastUpdatePostDateStruct":649,"startDateStruct":651,"completionDateStruct":653,"leadSponsor":655,"locationsCount":4},"100563750","exploring-the-impact-of-vr-based-acupuncture-treatment-on-patient-experience-and-doctor-patient-interaction-100563750","NCT06620224","Exploring the Impact of VR-based Acupuncture Treatment on Patient Experience and Doctor-patient Interaction.","Exploring the Impact of Virtual Reality-based Traditional Chinese Acupuncture Treatment on Patient Experience and Doctor-patient Interaction.","Inclusion Criteria:\n\n* general public and people see a doctor in the department of acupuncture\n\nExclusion Criteria:\n\n* participant refusing the intervention of the virtual reality",{"count":638,"type":23},20,[26],"Develop and establish a virtual reality acupuncture system, and introduce the technology acceptance model to systematically explore the impact of acupuncture treatment effectiveness and its related medical experience and doctor-patient interaction",[29,642],"Virtual Reality",[644,642,645,646,647],"Traditional Chinese Medicine Acupuncture","Technology Acceptance Model","Doctor-Patient Interaction","Medical Quality","2024-09-30",{"date":650,"type":44},"2024-10-01",{"date":652,"type":23},"2024-09-20",{"date":654,"type":23},"2025-08-31",{"name":561,"class":51},{"id":657,"slug":658,"hasResults":12,"nctId":659,"briefTitle":660,"officialTitle":660,"acronym":4,"eligibilityCriteria":661,"healthyVolunteers":12,"sex":18,"minAge":460,"maxAge":4,"enrollmentInfo":662,"targetDuration":4,"studyType":24,"phases":664,"briefSummary":665,"conditions":666,"keywords":669,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":670,"lastUpdatePostDateStruct":671,"startDateStruct":673,"completionDateStruct":675,"leadSponsor":677,"locationsCount":52},"100497122","acupuncture-as-adjuvant-therapy-for-glaucoma---protocol-for-a-randomized-controlled-trial-100497122","NCT05753137","Acupuncture as Adjuvant Therapy for Glaucoma - Protocol for a Randomized Controlled Trial","Inclusion Criteria:\n\n1. Primary open angle glaucoma diagnosed at least 3 months ago.\n2. Diagnosed with mild or moderate open angel glaucoma.\n3. Use 1 or 2 kinds of glaucoma drugs.\n4. Age ≥ 20 years old.\n5. Participants sign the informed consent and cooperate with the experimental procedures.\n\nExclusion Criteria:\n\n1. Accept any ophthalmic laser or surgery within one year.\n2. High myopia.\n3. Use of any drugs that affect intraocular pressure.\n4. Visual acuity with correction lower than 0.2.\n5. Previous or existing uveitis or retinopathy.\n6. Unable to receive acupuncture treatment continuously or allergic to acupuncture needles.\n7. Pregnancy or breastfeeding.\n8. Refusal to sign the informed consent form.",{"count":663,"type":23},50,[26],"This clinical trial used acupuncture as an adjunctive treatment for glaucoma patients. A randomized, controlled trial involving 50 subjects will be conducted and observed for 12 weeks to evaluate the clinical efficacy of acupuncture. This study aims to provide a reference for future clinical treatment guidelines.",[667,29,668],"Glaucoma","Intraocular Pressure",[667,29],"2024-06-30",{"date":672,"type":44},"2024-07-03",{"date":674,"type":44},"2023-06-28",{"date":676,"type":23},"2025-06-27",{"name":561,"class":51}]