[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"acute-care-medical\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:acute-care-medical":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":28,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100581663","functional-incremental-stepping-in-place-test-f-ist-validation-100581663",false,"NCT06853236","Functional Incremental Stepping in Place Test (F-IST) Validation","A Cardiorespiratory Fitness Test for Acute Illness: Validity, Reliability, and Clinical Utility of Functional Incremental Stepping-in-Place Test","F-IST","Inclusion Criteria:\n\n-Currently able to walk with or without a walking aid, such as a cane or walker or rollator\n\nExclusion Criteria:\n\nPregnancy\n\nspecifically related to cardiopulmonary testing\n\n* A recent significant change in resting ECG\n* Unstable angina\n* Uncontrolled cardiac dysrhythmias causing symptoms or hemodynamic compromise\n* Symptomatic severe aortic stenosis\n* Uncontrolled symptomatic heart failure\n* Acute pulmonary embolus or pulmonary infarction\n* Acute myocarditis or pericarditis\n* Suspected or known dissecting aneurysm\n* Acute systemic infection accompanied by fever, body aches, or swollen lymph glands\n* Left Main Coronary Stenosis\n* Moderate stenotic valvular heart disease\n* Electrolyte abnormalities\n* Severe arterial hypertension (\\>200 systolic, \\>110 diastolic) at rest\n* Tachydysrhythmia or bradydysrhythmia\n* Hypertrophic cardiomyopathy and other forms of outflow tract obstruction\n* Neuromuscular, musculoskeletal, or rheumatic disorders that are exacerbated by exercise\n* High degree AV block\n* Ventricular aneurysm\n* Uncontrolled metabolic disease (diabetes, thyrotoxicosis, or myxedema)\n* Chronic infectious disease (hepatitis, AIDS, mono)\n* Mental or physical impairment leading to inability to exercise adequately",true,"ALL","18 Years",{"count":21,"type":22},60,"ESTIMATED","OBSERVATIONAL","The purpose of this multi-site prospective study is to assess validity of a new step test called Functional-Incremental Stepping-in-place- Test (F-IST) compared to gold-standard cardiopulmonary exercise testing (CPET) and to physical function and health perception, respectively. The investigators will also assess test-retest reliability of the F-IST. The investigators hypothesize that the F-IST will have high validity and test-retest reliability to be used in field testing environments such as the ICU.",[26,27],"Intensive Care Medicine","Acute Care Medical",[29,30,31,32,33,34],"Cardio respiratory fitness","incremental step test","validity","reliability","physical function","graded exercise testing","RECRUITING","2026-03-16",{"date":38,"type":39},"2026-03-17","ACTUAL",{"date":41,"type":39},"2024-07-02",{"date":43,"type":22},"2026-07-02",{"name":45,"class":46},"Kirby Mayer","OTHER",2]