[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"acute-diverticulitis\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:acute-diverticulitis":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,41,76,102],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":21,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":40},"100645313","analysis-of-the-role-of-the-microbiota-in-diverticular-disease-100645313",false,"NCT07681505","Analysis of the Role of the Microbiota in Diverticular Disease","Analysis of the Role of the Microbiota in Diverticular Disease.","Inclusion Criteria:\n\n* Age 18 or older.\n* Signing of the informed consent form.\n* Assignment to one of the study groups mentioned above.\n\nExclusion Criteria:\n\n* An episode of acute diverticulitis located in the right colon or transverse colon.\n* Antibiotic treatment within the six weeks prior to the episode (except for antibiotics started in the emergency department or within 24 hours prior to sample collection).\n* Mechanical bowel preparation within the three weeks prior to sample collection.\n* Diagnosis of colorectal cancer.\n* Diagnosis of inflammatory bowel disease.\n* Failure to sign the informed consent form.","ALL","18 Years",{"count":19,"type":20},285,"ESTIMATED","24 Months","OBSERVATIONAL","A single-center, prospective observational cohort study conducted at the University Hospital of Navarra. The primary objective is to expand knowledge of diverticular disease and its pathological variants, as well as the influence of the microbiota in our environment, both clinically and molecularly; to describe the clinical and pathological characteristics of patients with diverticulosis and acute diverticulitis; to analyze any differences in the microbiota; and to identify the risk factors and groups associated with diverticular disease in order to establish the best strategies for prevention and treatment.",[25,26,27],"Diverticular Disease of Colon","Acute Diverticulitis","Gut Microbiota","NOT_YET_RECRUITING","2026-06-26",{"date":31,"type":32},"2026-07-02","ACTUAL",{"date":34,"type":20},"2027-06-01",{"date":36,"type":20},"2032-01-01",{"name":38,"class":39},"Hospital of Navarra","OTHER",1,{"id":42,"slug":43,"hasResults":11,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":47,"eligibilityCriteria":48,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":49,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":51,"conditions":52,"keywords":56,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":40},"100643139","aide-decision-support-for-anastomosis-or-colostomy-in-emergency-surgery-for-complicated-acute-diverticulitis-100643139","NCT07651072","AIDE: Decision Support for Anastomosis or Colostomy in Emergency Surgery for Complicated Acute Diverticulitis","AIDE: a Multicenter Observational Study to Support the Decision Between Anastomosis and Colostomy in Emergency Surgery for Complicated Acute Diverticulitis","AIDE\u002FOBS\u002F2025","Inclusion Criteria:\n\n* Age 18 years or older\n* Diagnosis of acute complicated diverticulitis requiring non-elective operative management\n* Emergency or urgent surgery for complicated diverticulitis, including surgery after failure of non-operative management\n* Minimally invasive approach: laparoscopic\u002Frobotic surgery\n* Patients undergoing sigmoid resection with primary anastomosis, Hartmann's procedure, or other operative strategy according to local practice\n* Availability of clinical and operative data\n* Local ethical approval, authorization, or waiver according to national and institutional regulations\n\nExclusion Criteria:\n\n* Age younger than 18 years\n* Elective surgery for diverticular disease\n* Uncomplicated diverticulitis managed non-operatively\n* Surgery performed for conditions not related to diverticulitis\n* Surgical procedures performed via primary open approach (i.e., no attempt at minimally invasive surgery), unless converted intraoperatively.\n* Lack of required consent or authorization for data use, when required by local regulations",{"count":50,"type":20},150,"The AIDE\u002FOBS study is a multicenter, observational, non-interventional study designed to collect standardized clinical, radiological, intraoperative visual, and surgical reasoning data from adult patients undergoing non-elective surgery for complicated acute diverticulitis.\n\nThe study focuses on patients requiring urgent or emergency operative management, including cases following failure of non-operative management. The main intraoperative decision of interest is the choice between sigmoid resection with primary anastomosis, with or without diverting stoma, and Hartmann's procedure.\n\nThe current phase aims to build a structured multimodal dataset and to validate and refine a preliminary expert-informed decision-support tool. The study does not modify standard clinical practice, surgical indication, operative strategy, or postoperative management. All treatment decisions remain at the discretion of the treating surgical team according to local practice.",[53,26,54,55],"Complicated Diverticulitis","Peritonitis","Perforated Diverticulitis",[57,58,59,60,61,62,63,64,65,66],"Perforated diverticulitis","Emergency surgery","Non-elective surgery","Primary anastomosis","Hartmann's procedure","Intraoperative decision-making","Artificial intelligence","Computer vision","Surgical video analysis","Multimodal dataset","2026-06-10",{"date":69,"type":32},"2026-06-16",{"date":71,"type":20},"2026-05-31",{"date":73,"type":20},"2028-04-30",{"name":75,"class":39},"IRCCS San Raffaele Roma",{"id":77,"slug":78,"hasResults":11,"nctId":79,"briefTitle":80,"officialTitle":81,"acronym":4,"eligibilityCriteria":82,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":83,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":85,"conditions":86,"keywords":89,"overallStatus":92,"whyStopped":4,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":40},"100536501","comparison-of-nom-for-acld-between-medical-and-surgical-ward-100536501","NCT06265649","Comparison of NOM for ACLD Between Medical and Surgical Ward","Acute Left Colon Diverticulitis: is it Still a Surgical Disease When Only Medical Treatment is Required? A Retrospective Study Based on Propensity Score Matching","Inclusion Criteria:\n\n* patients affected by ALCD using a contrast-enhanced CT scan at admission undergoing NOM\n\nExclusion Criteria:\n\n* immediate indication for surgery (i.e. patients with Hinchey III or IV ALCD or septic patients with Hinchey II)",{"count":84,"type":20},175,"In Europe, patients with acute left colon diverticulitis (ALCD) are usually admitted to surgical wards even when only medical treatment is required. The study compares ALCD non-operative management (NOM) between surgical and non-surgical environments regarding clinical outcomes, hospitalization length(LOS), and follow-up.",[87,88,26],"Diverticulitis","Colon Disease",[90,91],"diverticulitis","non-operative management","RECRUITING","2025-04-02",{"date":95,"type":32},"2025-04-04",{"date":97,"type":32},"2024-01-01",{"date":99,"type":20},"2026-01",{"name":101,"class":39},"Ospedali Riuniti Trieste",{"id":103,"slug":104,"hasResults":11,"nctId":105,"briefTitle":106,"officialTitle":106,"acronym":107,"eligibilityCriteria":108,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":109,"targetDuration":111,"studyType":22,"phases":4,"briefSummary":112,"conditions":113,"keywords":4,"overallStatus":92,"whyStopped":4,"lastUpdateSubmitDate":128,"lastUpdatePostDateStruct":129,"startDateStruct":131,"completionDateStruct":133,"leadSponsor":135,"locationsCount":40},"100335153","web-based-international-register-of-emergency-surgery-and-trauma-100335153","NCT03643718","Web-based International Register of Emergency Surgery and Trauma","WIRES-T","Inclusion Criteria:\n\n* Patients affected by an acute surgical disease\n* Patients with indication to be referred to the emergency surgeon attention\n* Patients to be operated or to be treated with non-operative approach without surgical intervention\n\nExclusion Criteria:\n\n* Patients not affected by an acute surgical disease\n* Patients without indication to be referred to the emergency surgeon attention",{"count":110,"type":20},10000,"2 Weeks","The WIRES-T project (Web-based International Registry of Emergency General Surgery and Trauma) has been set up to allow to all the EGS (Emergency General Surgery) and Trauma surgeons to register their activity and to obtain a worldwide register of traumatic and non traumatic surgical emergencies. This will give the opportunity to evaluate results on a macro-data basis and to give index allowing stratifying, evaluating and improving the outcomes.",[114,115,26,116,117,118,119,120,121,122,123,124,125,126,127],"Acute Appendicitis","Acute Cholecystitis","Post-operative Complications","Acute Pancreatitis","Perforated Gastro-duodenal Ulcers","Adhesive Small Bowell Occlusion","Colonic Neoplastic Emergencies","Gynecological Emergencies","Vascular Emergencies","Intestinal Ischemia","Abdominal Wall Hernia","Foreign Bodies","Caustic Ingestion","Trauma","2020-07-10",{"date":130,"type":32},"2020-07-14",{"date":132,"type":20},"2020-07",{"date":134,"type":20},"2030-09",{"name":136,"class":39},"A.O. Ospedale Papa Giovanni XXIII"]