[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"acute-exacerbation-copd\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:acute-exacerbation-copd":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,45],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100630169","effectiveness-of-nurse-led-interventions-on-respiratory-outcomes-in-hospitalized-patients-with-acute-exacerbation-of-chronic-obstructive-pulmonary-disease-100630169",false,"NCT07484178","Effectiveness of Nurse-Led Interventions on Respiratory Outcomes in Hospitalized Patients With Acute Exacerbation of Chronic Obstructive Pulmonary Disease","Effectiveness of Nurse-Led Interventions on Respiratory Outcomes in Hospitalized Patients With Acute Exacerbation of Chronic Obstructive Pulmonary Disease: A Randomized Control Trial","Inclusion Criteria:\n\n* Diagnosed cases of COPD admitted for acute exacerbation according to Global Initiative for Chronic Obstructive Lung Disease.\n* Adults aged \\> 40 years (WHO, 2023; GOLD, 2024).\n* Both genders (male \\& female).\n* Hemodynamically stable at the time of enrollment in terms of vital signs (e.g., blood pressure \\> 90\u002F60 mmHg, heart rate between 60-100 bpm) to safely undergo nursing interventions without acute risk (Jarhyan et al., 2021).\n* Dyspnea Grade ≥ 2 on the mMRC Scale (Mahler and Wells, 1988).\n* Blood Oxygen Saturation (SpO₂) ≥ 88% on Room Air or Oxygen Therapy (O'Driscoll, 2017).\n\nExclusion Criteria:\n\n* Dyspnea due to cardio-pulmonary disease or other co-morbidities.\n* Patients on mechanical ventilation and ICU admission.\n* Patients with mental disorders.\n* Patients with upper airway obstruction.","ALL","40 Years",{"count":19,"type":20},68,"ESTIMATED","INTERVENTIONAL",[23],"NA","The goal of this clinical trial is to evaluate whether respiratory nursing interventions can improve respiratory outcomes in patients hospitalized with acute exacerbation of Chronic Obstructive Pulmonary Disease (COPD). The main questions it aims to answer are:\n\nDo respiratory nursing interventions improve dyspnea levels measured by the Modified Medical Research Council (mMRC) Dyspnea Scale? Do these interventions improve oxygen saturation and pulmonary function (FVC, FEV1, and FEV1\u002FFVC ratio)?\n\nResearchers will compare patients receiving respiratory nursing interventions plus routine hospital care with patients receiving routine hospital care alone to determine whether the interventions improve respiratory outcomes.\n\nParticipants will:\n\nUndergo baseline assessment using the mMRC Dyspnea Scale, pulse oximetry, and pulmonary function tests.\n\nReceive either respiratory nursing interventions (deep breathing exercises, chest percussion, postural drainage, and lukewarm water intake) along with routine care or routine hospital care alone.\n\nBe reassessed after the intervention period using the same respiratory outcome measures.",[26],"Acute Exacerbation Copd",[28,29,30,31],"Nursing Intervention","COPD","Acute Exacerbation","Respiratory outcomes","NOT_YET_RECRUITING","2026-04-10",{"date":35,"type":36},"2026-04-15","ACTUAL",{"date":38,"type":20},"2026-05-02",{"date":40,"type":20},"2026-10-20",{"name":42,"class":43},"University of Health Sciences Lahore","OTHER",1,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":4,"eligibilityCriteria":51,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":52,"enrollmentInfo":53,"targetDuration":4,"studyType":55,"phases":4,"briefSummary":56,"conditions":57,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":59,"lastUpdatePostDateStruct":60,"startDateStruct":62,"completionDateStruct":64,"leadSponsor":66,"locationsCount":4},"100527083","prediction-of-outcome-of-non-invasive-ventilation-copd-patients-by-assessment-of-diaphragmatic-performance-100527083","NCT06143150","Prediction of Outcome of Non Invasive Ventilation COPD Patients by Assessment of Diaphragmatic Performance","Can Transthoracic Ultrasound Assessment of the Diaphragmatic Performance Predict the Outcome of Non Invasive Ventilation in Critically Ill COPD Patients With Acute Exacerbation","Inclusion Criteria:\n\n* One Hundred fifty five critically ill COPD patients admitted to respiratory intensive care unit\n* Diagnosis of COPD and COPD exacerbation is fulfilled according to GOLD 2022 criteria\n* Age\\>40years\n\nExclusion Criteria:\n\n* Age ˂ 40 years.\n* Refusal to participate in the study.\n* Patients with morbid obesity (BMI\\>40).\n* Absolute indication for intubation like coma ,hemodynamic instability, or life threatening arrhythmia.\n* Contraindication to NIV like untreated pneumothorax, pneumothorax with air leak, widespread facial burn or trauma, tracheotomy, or active upper gastrointestinal bleeding.","90 Years",{"count":54,"type":20},155,"OBSERVATIONAL","Transthoracic ultrasonographic assessment of the diaphragmatic performance as a predictor for the outcome of NIV in critically ill COPD patients with acute exacerbation.",[58],"Acute Exacerbation COPD","2023-11-20",{"date":61,"type":36},"2023-11-22",{"date":63,"type":20},"2023-11-15",{"date":65,"type":20},"2027-12-15",{"name":67,"class":43},"Assiut University"]