[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"acute-medical-conditions\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:acute-medical-conditions":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,52],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":41,"startDateStruct":44,"completionDateStruct":46,"leadSponsor":48,"locationsCount":51},"100609786","transcutaneous-auricular-vagus-enhanced-recovery-in-the-neuroicu-100609786",false,"NCT07219108","Transcutaneous Auricular Vagus Enhanced Recovery in the NeuroICU","The TAVERN Trial: Transcutaneous Auricular Vagus Enhanced Recovery in the NeuroICU - A Study of Clinical Outcomes and Cost Reduction","TAVERN","Inclusion Criteria:\n\n* Age ≥18\n* Admission to the NeuroICU within 36 hours of onset of an acute medical condition.\n* Patient or authorized legal representative should be able to provide consent within 36 hours of ICU arrival\n* Presence of at least one predictor of critical illness and\u002For severe brain \u002F spinal cord injury:\n\n  * Glasgow Coma Scale GCS \\>3 \\& \\\u003C= 12 at admission\n  * NIH stroke scale of 6 or greater\n  * Requirement for ongoing mechanical ventilation\n  * Requirement for ongoing vasopressor support\n  * Diagnosis of subarachnoid hemorrhage\n  * Diagnosis of intracerebral hemorrhage with hematoma volume \\> 5 ml\n  * Diagnosis of moderate-severe traumatic brain injury (GCS \\>3 \\& \\\u003C= 12)\n  * Refractory Status epilepticus requiring continuous sedative infusions\n\nExclusion Criteria:\n\n* Systemic immunosuppression\n* Receiving ongoing cancer therapy\n* Implanted electrical device (e.g., pacemaker, stimulator)\n* Bradycardia on admission (Sustained bradycardia on arrival with a heart rate \\\u003C 50 bpm for \\>5 minutes)\n* Risk of imminent death or limitation of care (e.g., Glasgow Coma Scale of 3, pupillary dilatation)\n* Expected ICU stay of less than 72 hours, as determined by attending physician or ICU fellow\n* Pregnancy\n* COVID-19","ALL","18 Years",{"count":20,"type":21},160,"ESTIMATED","INTERVENTIONAL",[24],"NA","This study will demonstrate the impact of taVNS on reducing adverse events in NeuroICU patients, determine if taVNS reduces length of stay, and quantify the economic benefits of taVNS implementation in a broader neurocritical care population.",[27,28],"Acute Neurological Injury","Acute Medical Conditions",[30,31,32,33,34,35,36,37,38],"vagal nerve stimulation","pathologic process","acute medical condition","brain diseases","central nervous system diseases","spine cord injury","vascular diseases","hemorrhage","acute neurological condition","RECRUITING","2025-10-20",{"date":42,"type":43},"2025-10-21","ACTUAL",{"date":45,"type":43},"2025-09-24",{"date":47,"type":21},"2027-09-23",{"name":49,"class":50},"Washington University School of Medicine","OTHER",1,{"id":53,"slug":54,"hasResults":11,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":4,"eligibilityCriteria":58,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":59,"targetDuration":4,"studyType":61,"phases":4,"briefSummary":62,"conditions":63,"keywords":66,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":79},"100538351","alert-frequency-nurse-and-patient-satisfaction-with-a-wcvsm-software-across-health-care-systems-and-cultures-100538351","NCT06289699","Alert Frequency, Nurse, and Patient Satisfaction With a wCVSM Software Across Health Care Systems and Cultures","Alert Frequency, Nurse, and Patient Satisfaction With a Continuous Wireless Vital Sign Monitoring Software Across Health Care Systems and Cultures","Inclusion Criteria:\n\n* Adults (≥18 years)\n* Expected stay in the hospital ≥2 days\n* Admitted for surgery with expected duration of surgery \\>2 hours or admitted for acute medical condition with at least one of the following vital sign deviations within 24 hours of acute admission, recorded by the staff\n\n  * RR \\> 21 breaths pr minute\n  * RR \\\u003C 11 breaths pr minute\n  * Pulse (P) \\> 91 beats pr minute\n  * Pulse (P) \\\u003C 50 beats pr minute\n  * SpO2 \\\u003C 94 % without oxygen supplementation\n  * Systolic BP \\\u003C 110 mmHg\n  * Systolic BP \\> 220 mmHg\n\nExclusion Criteria:\n\n* Participant expected not to cooperate with study procedures.\n* Allergy to plaster or silicone.\n* Pacemaker or Implantable Cardioverter Defibrillator (ICD) device.\n* Inability to give informed consent.",{"count":60,"type":21},100,"OBSERVATIONAL","The goal of this prospective, international multi-centre pilot study is to assess the functionality and user experience of a new vital sign monitoring system in 20 patients and 20 nurses in the general ward at each centre. The patients will be monitored with a wireless, continuous vital sign monitoring systems and answer a questionnaire afterwards. They will in addition have vital signs monitored as per standard practice. The nurses will answer a questionnaire after having had the responsibility for a monitored patient for a full shift. The main aims are: To determine the frequency of alerts activated in the app in relation to the alerts that should be activated based on measured data, to explore current practices of in-hospital monitoring by semi-structured interviews to map differences across systems and to test nurse and patient satisfaction.",[64,65,28],"User Experience","Postoperative Complications",[67,68,69,64,65,28],"continuous wireless vital sign monitoring","vital sign deviation","healthcare system and culture","2025-08-11",{"date":72,"type":43},"2025-08-12",{"date":74,"type":43},"2024-02-26",{"date":76,"type":21},"2026-12-31",{"name":78,"class":50},"Christian S. Meyhoff",5]