[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"acute-pulmonary-embolism-pe\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:acute-pulmonary-embolism-pe":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,42,70],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100569674","evaluating-the-efficacy-safety-and-long-term-functional-outcomes-of-percutaneous-mechanical-aspiration-thrombectomy-for-treatment-of-acute-pulmonary-embolism-using-the-alphavac-multipurpose-mechanical-aspiration-mma-f1885-system-100569674",false,"NCT06697314","Evaluating the Efficacy, Safety and Long Term Functional Outcomes of Percutaneous Mechanical Aspiration Thrombectomy for Treatment of Acute Pulmonary Embolism Using the AlphaVac Multipurpose Mechanical Aspiration (MMA) F1885 System","Prospective, Multicenter, Multi-national, Single Arm Trial Evaluating the Efficacy, Safety and Long Term Functional Outcomes of Percutaneous Mechanical Aspiration Thrombectomy for Treatment of Acute Pulmonary Embolism Using the AlphaVac Multipurpose Mechanical Aspiration (MMA) F1885 System","RECOVER-AV","Inclusion Criteria:\n\n* Symptomatic, CTPA-proven acute PE with a maximum duration of symptoms of 14 days, showing a filling defect in at least one main or proximal lobar pulmonary artery\n* RV\u002FLV diameter ratio ≥ 1.0 assessed by CTPA\n* Serum troponin levels above upper limit of normal as per hospital policy\n* ≥ 18 years of age\n* At least one of the following:\n\n  1. Electrocardiogram (ECG)-documented tachycardia with heart rate ≥ 100 BPM, not due to hypovolemia, arrhythmia or sepsis\n  2. Systolic blood pressure ≤ 110mmHg for at least 15 minutes\n  3. Respiratory rate \\> 20 breaths per minuted. Oxygen saturation on pulse oximetry (SpO2) \\\u003C 90% (or partial arterial oxygen pressure \\\u003C 60 mmHg) at rest while breathing room air\n  4. Known history of heart failure\n* Willing and able to provide written informed consent prior to receiving study specific procedures.\n\nExclusion Criteria:\n\n* A contraindication to therapeutic anticoagulation\n* Any comorbid diagnosis consistent with a life expectancy of less than 1 year (e.g., stage 4 cancer)\n* Known serious, uncontrolled sensitivity to radiographic agents\n* Cardiac arrest within last 14 days without documented evidence of recovery of conscious level to Glasgow Coma Scale \\>12\n* Indication for ECMO\n* Pregnant or breastfeeding\n* Participation in another investigational drug or device study that study may confound the results of this study. Studies requiring extended follow-up for products that were investigational but have since become commercially available are not considered investigational studies.\n* Other medical, social, or psychological conditions that, in the opinion of the Investigator, precludes the patient from appropriate consent, could limit the patient's ability to participate in the study, including compliance with follow- up requirements, or that could impact the scientific integrity of the study.\n* History of congenital or acquired bleeding disorder predisposing to hemorrhagic state\n* Platelet count \\\u003C 100,000\u002FμL\n* Any advanced reperfusion therapy for pulmonary embolism within 30 days of the index procedure (e.g lysis, surgery, catheter intervention)\n* A known clot in transit\n* IVC filter\n* A do not resuscitate limitation at inclusion in the study\n* Deprived of liberty or under court protection","ALL","18 Years",{"count":20,"type":21},256,"ESTIMATED","INTERVENTIONAL",[24],"NA","To evaluate the efficacy, safety, and long-term functional outcomes of percutaneous mechanical aspiration thrombectomy using the AlphaVac Multipurpose Mechanical Aspiration (MMA) F1885 System for the treatment of acute pulmonary embolism.",[27,28],"Acute Pulmonary Embolism (PE)","Pulmonary Embolism","RECRUITING","2025-09-23",{"date":32,"type":33},"2025-09-26","ACTUAL",{"date":35,"type":33},"2025-06-15",{"date":37,"type":21},"2028-06",{"name":39,"class":40},"Angiodynamics, Inc.","INDUSTRY",1,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":4,"eligibilityCriteria":48,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":49,"targetDuration":4,"studyType":51,"phases":4,"briefSummary":52,"conditions":53,"keywords":54,"overallStatus":59,"whyStopped":4,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":63,"completionDateStruct":65,"leadSponsor":67,"locationsCount":41},"100601196","assessment-of-right-ventricular-function-after-acute-pulmonary-embolism-a-comparison-of-speckle-tracking-strain-and-conventional-echocardiographic-parameters-100601196","NCT07107347","Assessment of Right Ventricular Function After Acute Pulmonary Embolism: a Comparison of Speckle Tracking Strain and Conventional Echocardiographic Parameters","Assessment of Right Ventricular Function for Diagnosis and Prognosis After Acute Pulmonary Embolism: a Comparison of Speckle Tracking Strain and Conventional Echocardiographic Parameters","Inclusion Criteria:\n\n1. Adults ≥18 years.\n2. Confirmed acute PE (via CT pulmonary angiography).(4,6)\n3. Echocardiography performed within 24 hours of diagnosis.\n\nExclusion Criteria:\n\n1. Pre-existing significant RV dysfunction (e.g., due to chronic pulmonary hypertension, cor pulmonale or congenital heart disease).\n2. History of coronary artery disease.\n3. Impaired LV systolic function, ejection fraction \\\u003C50%.\n4. Moderate to severe valvular heart disease.\n5. Prior document of an episode of pulmonary embolism.\n6. Poor acoustic window.\n7. Hemodynamic instability",{"count":50,"type":21},100,"OBSERVATIONAL","Echocardiographic Assessment:\n\nPerformed within 24h of PE diagnosis Conventional parameters: TAPSE, RV FAC, RV\u002FLV ratio, tricuspid S', PASP STE parameters: RV free wall longitudinal strain (RVFWS), global longitudinal strain (GLS) if feasible All measurements averaged over 3 cardiac cycles (sinus) or 5 (AF)\n\nFollow-up data:\n\nICU\u002Fhospital LOS Need for vasopressors\u002Fmechanical ventilation In-hospital and 30-day mortality",[27],[55,56,57,58],"acute pulmonary embolism (PE)","STE","right ventricle strain","speckle tracking strain","NOT_YET_RECRUITING","2025-08-12",{"date":62,"type":33},"2025-08-14",{"date":64,"type":21},"2025-09",{"date":66,"type":21},"2028-03",{"name":68,"class":69},"Assiut University","OTHER",{"id":71,"slug":72,"hasResults":11,"nctId":73,"briefTitle":74,"officialTitle":74,"acronym":75,"eligibilityCriteria":76,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":77,"enrollmentInfo":78,"targetDuration":80,"studyType":51,"phases":4,"briefSummary":81,"conditions":82,"keywords":83,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":41},"100560935","the-prognostic-value-of-anion-gap-in-predicting-mortality-among-patients-with-acute-pulmonary-embolism-100560935","NCT06583616","The Prognostic Value of Anion Gap in Predicting Mortality Among Patients With Acute Pulmonary Embolism","PRAGUE-PE","Inclusion Criteria:\n\n* age: 18 - 70 years old\n* patient with acute pulmonary embolism\n\nExclusion Criteria -- patient with history of:\n\n* heart failure\n* valvular heart disease\n* chronic obstructive pulmonary disease\n* congenital heart disease\n* sepsis\n* chronic kidney disease","70 Years",{"count":79,"type":21},20,"7 Days","This study aims to evaluate the prognostic value of the anion gap in predicting mortality among patients with acute pulmonary embolism.\n\nResearchers will collect information based on hospital registry as secondary data of in patient who had diagnosed as acute pulmonary embolism by using computed tomography scan (CT scan). The data consist of demographic data, clinical presentation, laboratory, and CT scan were collected from hospital registry by reviewing medical record. Then, the data was analyzed by using IBM SPSS Statistics v26.",[27],[84,85,86],"anion gap","acute pulmonary embolism","mortality","2024-09-02",{"date":89,"type":33},"2024-09-04",{"date":91,"type":33},"2023-01-01",{"date":93,"type":21},"2024-09-30",{"name":95,"class":69},"Universitas Diponegoro"]