[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"acute-respiratory-distress-syndrome-due-to-covid-19\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:acute-respiratory-distress-syndrome-due-to-covid-19":24},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,38],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":4,"briefSummary":21,"conditions":22,"keywords":4,"overallStatus":26,"whyStopped":4,"lastUpdateSubmitDate":27,"lastUpdatePostDateStruct":28,"startDateStruct":31,"completionDateStruct":32,"leadSponsor":34,"locationsCount":37},"100596937","post-intensive-care-syndromes-in-pregnant-patients-with-respiratory-failure-and-covid-19-compared-to-non-pregnant-patients-with-respiratory-failure-and-covid-19-100596937",false,"NCT07051967","Post-intensive Care Syndromes in Pregnant Patients With Respiratory Failure and COVID-19 Compared to Non-pregnant Patients With Respiratory Failure and COVID-19","Inclusion Criteria:\n\n* Age: 18 years and older\n* Admission to a Charité intensive care unit and follow-up examination by the Post-Intensive-Care-Syndrome (PICS) outpatient clinic of the Department of Anesthesiology and Intensive Care Medicine between March 27, 2020 and May 6, 2024.\n* COVID-19 infection in temporal assocoation with the intensive care unit admission.\n* Intensive care unit admission with lung failure or development of lung failure in the course of intensive care unit treatment.\n* Admission to the intensive care unit with lung failure or development of lung failure during intensive care unit stay.\n\nExclusion Criteria:\n\n* Gender: Male\n* Diagnosis: Non-COVID or no respiratory failure","ALL","18 Years",{"count":18,"type":19},40,"ESTIMATED","OBSERVATIONAL","The aim of this study is to characterize patients in the Post-Intensive-Care-Syndrome (PICS) outpatient clinic based on routine data and to evaluate their treatment outcome over the course of their treatment. For this purpose, data sets from approx. 40 patients who were treated in the intensive care unit subsequently evaluated in the PICS outpatient clinic between March 27, 2020, and May 6, 2024, will be analyzed.",[23,24,25],"COVID-19","Acute Respiratory Distress Syndrome Due to COVID-19","Pregnancy Related","RECRUITING","2025-09-22",{"date":29,"type":30},"2025-09-25","ACTUAL",{"date":27,"type":30},{"date":33,"type":19},"2026-06-30",{"name":35,"class":36},"Charite University, Berlin, Germany","OTHER",1,{"id":39,"slug":40,"hasResults":11,"nctId":41,"briefTitle":42,"officialTitle":43,"acronym":44,"eligibilityCriteria":45,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":46,"enrollmentInfo":47,"targetDuration":4,"studyType":49,"phases":50,"briefSummary":52,"conditions":53,"keywords":59,"overallStatus":26,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":73},"100482474","trial-of-venovenous-ecmo-to-de-sedate-extubate-and-mobilise-in-hypoxic-respiratory-failure-100482474","NCT05562505","Trial of Venovenous ECMO to De-Sedate, Extubate and Mobilise in Hypoxic Respiratory Failure","A Randomised Controlled Trial of Venovenous ECMO to De-Sedate, Extubate and Mobilise in Hypoxic Respiratory Failure","REDEEM","Inclusion Criteria:\n\n1. Patients ≥18 to 65 years old\n2. Acute hypoxemic respiratory failure characterised by new or worsening respiratory symptoms developing within 2 weeks prior to the onset of need for oxygen or respiratory support\n3. Mechanical ventilation of \\\u003C7 days\n4. Moderate to severe respiratory failure, as demonstrated by two P:F ratios \\\u003C150mmHg at least 6 hours apart. Arterial Blood Gases (ABG) with P:F ratio \\> 150mmHg are permitted between the two trial inclusion ABGs.\n5. Trial of proning (unless contraindicated)\n\nExclusion Criteria:\n\n1. The patient will be extubated today or tomorrow (i.e. will not remain intubated and ventilated the day after tomorrow)\n2. Cardiogenic cause of respiratory failure\n3. Chronic hypercapnic respiratory failure defined as PaCO2 \\> 60 mmHg in the outpatient setting\n4. Home mechanical ventilation (non-invasive ventilation or via tracheotomy) except for CPAP\u002FBIPAP used solely for sleep disordered breathing\n5. Confirmed diffuse alveolar haemorrhage from vasculitis\n6. Neurologic conditions, i.e. undergoing treatment for intracranial hypertension\n7. Currently receiving any form of ECMO (e.g., venovenous, venoarterial, or hybrid configuration)\n8. Patient needing immediate VV ECMO (as per EOLIA criteria)\n9. The patient is moribund and deemed unlikely to survive past 24 hours (as determined by the clinical team)\n10. The patient is being transitioned to palliative care\n11. Contraindications to anticoagulation (e.g., active GI bleeding, bleeding predisposition, severe trauma)\n12. Previous hypersensitivity\u002Fanaphylactic reaction to heparin or heparin-induced thrombocytopenia\n13. Participation or Consent is declined, OR\n14. Unable to identify or Contact surrogate decision maker.","65 Years",{"count":48,"type":19},140,"INTERVENTIONAL",[51],"NA","To determine whether a strategy of adding venovenous ECMO to mechanical ventilation, as compared to mechanical ventilation alone, increases the number of intensive care free days at day 60, in patients with moderate to severe acute hypoxic respiratory failure.",[54,55,24,56,57,58],"Mechanical Ventilation Complication","Hypoxemia","COVID-19 Respiratory Infection","Pneumonia","Extracorporeal Membrane Oxygenation",[60,61,58,62,63],"Intensive Care Unit","ECMO","Mechanical Ventilation","Early ECMO","2024-08-06",{"date":66,"type":30},"2024-08-09",{"date":68,"type":30},"2022-11-28",{"date":70,"type":19},"2027-01-31",{"name":72,"class":36},"Australian and New Zealand Intensive Care Research Centre",7]