[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"acute\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:acute":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,46],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":4},"100602783","in-this-study-we-are-testing-whether-combining-two-interventions-in-the-early-stages-of-tinnitus-is-more-effective-in-quieting-tinnitus-than-using-one-treatment-alone-in-the-later-stages-of-tinnitus-100602783",false,"NCT07128004","In This Study, we Are Testing Whether Combining Two Interventions, in the Early Stages of Tinnitus, is More Effective in Quieting Tinnitus Than Using One Treatment Alone in the Later Stages of Tinnitus","Effect of Combined Acoustic Ripples and Transcranial Direct Current Stimulation on the Symptoms of New-Onset Subjective Tinnitus","ATtDCS","Inclusion Criteria:\n\n* The presence of tinnitus (persistent sound heard in one or both ears that is not coming from an external sound source or actual sounds being generated inside your body such as turbulent blood flow), which has persisted for at least 3 days, and began within the last 8 weeks. You do not need to be aware of the tinnitus all the time, but it must be persistent in the sense that is can always hear it if you listen out for it, and there is not enough other sounds around to mask it.\n* Age 18 or over\n* The ability to make and communicate an informed choice about whether to take part in the study\n* The ability to sit still and comfortably in a comfortable chair for around 1 hour at a time.\n\nExclusion Criteria:\n\n* Tinnitus due to a physical sound source in the body, such as turbulent blood flow or muscle contractions in the middle ear.\n* Presence of tinnitus over a period of 8 weeks\n* Severe or profound hearing loss at high frequencies in the tinnitus ear(s), such that you could not properly hear the sounds used in the study\n* Any implanted electronic device, such as a pacemaker, cochlear implant, bone-anchored hearing aid, nerve stimulator, deep brain stimulator or spinal cord stimulator\n* Any areas of broken skin on the parts of the scalp where tDCS is applied\n* Ménière's disease\n* Any abnormality of brain structure (e.g. stroke, tumour), or other neurological disorder (e.g. multiple sclerosis or epilepsy)\n* The ongoing use of sedating medications, or certain other nerve- or brain-acting medications\n* A current mental health condition of sufficient severity to prevent certain activities of everyday life\n\nIn addition to these criteria, the researcher might have other reasons to suspect that participation is either contraindicated, or might be unsuitable. In such cases, the researcher should discuss these concerns with the potential participant and\u002For a senior member of the research team. Participation should only proceed if all those involved in these discussions agree it should.\n\n\\-","ALL","18 Years",{"count":20,"type":21},80,"ESTIMATED","INTERVENTIONAL",[24],"NA","* Tinnitus affects one in seven adults long-term\n* Once present persistently for 4 weeks, tinnitus does not usually disappear\n* People generally become less aware of, and less affected by, their tinnitus over time\n* Only one in six people with tinnitus suffers a long-term negative impact on their life\n* Current treatments can help to reduce the impact of tinnitus, but not silence the sound\n* Treatments have only so far been tested once tinnitus has been present longer than 6 months\n* In this study, the researchers are testing whether combining two interventions, in the early stages of tinnitus, is more effective in quieting tinnitus than using one treatment alone in the later stages of tinnitus\n* One intervention (acoustic ripples) involves playing sounds through headphones for up to 60 minutes per day, and is mostly done in your own time\n* The other intervention (transcranial direct current stimulation: tDCS) involves applying a weak electrical current to the volunteer's scalp using sponges soaked in salt water. This is performed in Newcastle University Medical School for a total of 8 sessions of 40 minutes each, spread over 4 weeks\n* Half the volunteers will receive the 'real' intervention, and half a 'sham' or 'placebo' version. This will be randomly determined, and the volunteers or the research team will not known which you are receiving until the end of the study\n* When the study ends, all volunteers will be able to use the 'real' intervention sounds in their own time, for as long as they wish, if they want to do so. No volunteers will be able to receive tDCS after the end of the study.\n* All volunteers also complete questionnaires about their tinnitus, related symptoms and general health, and have hearing tests plus EEG (electrical brainwave) recordings\n* The study is very low-risk, but does involve a total of 10 visits of around an hour each to Newcastle University Medical School over around a month. These can be arranged flexibly, including daytimes, evenings and weekends\n* The researchers will pay all reasonable travel expenses, and £10 per hour for the volunteer's time in participating\n* The study only completely ends 6 months after the date the tinnitus first started. At this point, the researchers will send some questionnaires to complete only. There is nothing to do for the study in between the tenth visit and this six-month questionnaire.",[27,28],"Tinnitus","Acute",[30,31,32,33],"Acute Tinnitus","Treatment","Sound therapy","tDCS","NOT_YET_RECRUITING","2025-08-13",{"date":37,"type":38},"2025-08-17","ACTUAL",{"date":40,"type":21},"2025-08-05",{"date":42,"type":21},"2027-03-09",{"name":44,"class":45},"Newcastle University","OTHER",{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":4,"eligibilityCriteria":52,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":53,"enrollmentInfo":54,"targetDuration":4,"studyType":56,"phases":4,"briefSummary":57,"conditions":58,"keywords":60,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":4},"100566286","prediction-of-acute-pancreatitis-outcome-100566286","NCT06653205","Prediction of Acute Pancreatitis Outcome","Systemic Inflammation Response Index and Systemic Immune Inflammation Index and Prediction of Clinical Outcome in Acute Pancreatitis","Inclusion Criteria:\n\nPatients age \\>18 years old Serum amylase \\>3 times the upper limit of normal. abdominal pain consistent with acute pancreatitis. Typical abdominal ultrasonography and tomography findings in the routine imaging of the patients were accepted as acute pancreatitis.\n\nPatient complaint of abdominal pain -\n\nExclusion Criteria:\n\nliver diseases patients renal diseases patients malignancy patients\n\n\\-","75 Years",{"count":55,"type":21},47,"OBSERVATIONAL","Aim of study prediction of acute pancreatitis outcome by using cheap and available laboratory resources",[28,59],"Pancreatitis",[61,62],"Acute pancreatitis","Outcome","2024-10-21",{"date":65,"type":38},"2024-10-22",{"date":67,"type":21},"2024-11-01",{"date":69,"type":21},"2027-01",{"name":71,"class":45},"Assiut University"]