[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"adenotonsillar-hypertrophy\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:adenotonsillar-hypertrophy":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,42,81,111,139],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100639228","conox-guided-anesthesia-in-pediatric-adenotonsillectomy-100639228",false,"NCT07577154","Conox-Guided Anesthesia in Pediatric Adenotonsillectomy","A Randomized Controlled Trial Evaluating the Effect of qCON\u002FqNOX-Guided Anesthesia on Clinical Outcomes in Pediatric Adenotonsillectomy","Inclusion Criteria:\n\nChildren aged 3 to 12 years ASA physical status I-II Scheduled for elective adenotonsillectomy No acute infection or systemic disease Parent or legal guardian able to provide written informed consent\n\nExclusion Criteria:\n\nSkin lesions or anatomical abnormalities preventing placement of EEG electrodes History of neurological disease, including epilepsy or neurological syndromes Body mass index above the 95th percentile for age Previous pharyngeal surgery History of anesthesia-related complications Absence of written informed consent from a parent or legal guardian","ALL","3 Years","12 Years",{"count":20,"type":21},128,"ESTIMATED","INTERVENTIONAL",[24],"NA","This study aims to evaluate the effect of Conox (qCON\u002FqNOX)-guided anesthesia on intraoperative anesthetic drug consumption and postoperative outcomes in pediatric patients undergoing adenotonsillectomy. Conox is a non-invasive EEG-based monitoring system that provides indices of both hypnosis and nociception.\n\nIn this randomized controlled trial, children aged 3-12 years will be assigned to either a Conox-guided anesthesia group or a standard monitoring group. The primary outcome of the study is total intraoperative opioid consumption, assessed from anesthesia induction to the end of surgery. Secondary outcomes include emergence time, extubation time, postoperative agitation, pain scores, and correlation between qCON\u002FqNOX values and hemodynamic parameters.",[27,28],"Adenotonsillar Hypertrophy","Postoperative Pain","RECRUITING","2026-05-05",{"date":32,"type":33},"2026-05-11","ACTUAL",{"date":35,"type":33},"2026-03-01",{"date":37,"type":21},"2026-09-01",{"name":39,"class":40},"Kayseri City Hospital","OTHER_GOV",1,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":48,"eligibilityCriteria":49,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":50,"enrollmentInfo":51,"targetDuration":4,"studyType":22,"phases":53,"briefSummary":54,"conditions":55,"keywords":56,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":41},"100606455","teleconsultation-vs-face-to-face-evaluation-for-perioperative-respiratory-events-in-pediatric-adenotonsillectomy-100606455","NCT07175779","Teleconsultation vs Face-to-Face Evaluation for Perioperative Respiratory Events in Pediatric Adenotonsillectomy","Effect of Teleconsultation Compared to Face-to-Face Evaluation on Perioperative Respiratory Events in Pediatric Adenotonsillectomy: A Randomized Non Inferiority Trial","Teleped","Inclusion Criteria:\n\n* Pediatric patients (up to 16 years of age) undergoing elective tonsillectomy or adenotonsillectomy\n* ASA (American Society of Anesthesiologists) physical status I to III,\n* Patients who have a parent or legal guardian able and willing to provide informed consent.\n\nExclusion Criteria:\n\n* Parent or guardian unable or unwilling to provide informed consent,\n* Refusal to participate by parent\u002Fguardian,\n* Patients with contraindications to general anesthesia,\n* Known allergy to any drugs used in the anesthetic protocol.\n* Potential difficult airway,\n* Poorly controlled chronic illness (e.g. asthma),\n* Cardiac disease ,\n* Genetic disorder,\n* Haemoglobinopathy, anemia or clotting problem,\n* Complex physical disability,\n* Request from the patient or carer","16 Years",{"count":52,"type":21},106,[24],"The goal of this clinical trial is to assess whether preoperative anesthesia teleconsultation is at least equivalent to in-person consultation in preventing perioperative respiratory adverse events (such temporary reduction in oxygen levels in the blood) in the operating room and in the first 24 hours after the surgery in pediatric adenotonsillectomy.\n\nResearchers will compare the teleconsultation to in-person consultation to see if there is a difference in the frequency of respiratory adverse events in the operating room and during the first 24 hours after adenotonsillectomy.\n\nParticipants will:\n\n\\- undergo a traditional in-person anesthesiology consultation scheduled at the hospital or a online preoperative anesthesiology teleconsultation.",[27],[57,58,59,60,61,62,63,64,65,66,67,68,69,70],"Anesthesia Consultation","Face-to-Face Visit","Remote consultation","Patient anxiety","Patient Satisfaction","Lost Work Time","Distance Traveled","Virtual Care","Digital Health","Telemedicine","Perioperative Care","Perioperative respiratory adverse events (PRAE)","Adenotonsillectomy","Tonsillectomy","2026-03-13",{"date":73,"type":33},"2026-03-16",{"date":75,"type":33},"2025-12-11",{"date":77,"type":21},"2027-05",{"name":79,"class":80},"Andrea Saporito","OTHER",{"id":82,"slug":83,"hasResults":11,"nctId":84,"briefTitle":85,"officialTitle":85,"acronym":86,"eligibilityCriteria":87,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":88,"enrollmentInfo":89,"targetDuration":4,"studyType":22,"phases":91,"briefSummary":93,"conditions":94,"keywords":95,"overallStatus":101,"whyStopped":4,"lastUpdateSubmitDate":102,"lastUpdatePostDateStruct":103,"startDateStruct":105,"completionDateStruct":107,"leadSponsor":109,"locationsCount":4},"100607865","phase-4-remiazolam-vs-propofol-total-intravenous-anesthesia-on-postoperative-neurodevelopment-after-general-anesthesia-in-children-100607865","NCT07194109","Remiazolam vs Propofol Total Intravenous Anesthesia on Postoperative Neurodevelopment After General Anesthesia in Children","REMPPON","Inclusion Criteria:\n\n1. Age: 3-6 years old;\n2. Planned to undergo elective non-neurological, non-cardiac, and non-liver surgery under general anesthesia (abdominal surgery, orthopedic surgery, urological surgery, otolaryngological surgery, etc.);\n3. Expected anesthesia duration to be more than 30 minutes;\n4. ASA classification I-II;\n5. BMI 14-25 kg\u002Fm2;\n6. Postoperative plan not to be admitted to ICU;\n7. Parents or legal guardians of the child have given informed consent;\n8. Capable of communicating in Chinese.\n\nExclusion Criteria:\n\n1. Those who were exposed to general anesthetic drugs during infancy or in the late pregnancy of the mother;\n2. Known chromosomal abnormalities or other known acquired or congenital diseases that may affect neural development, such as cerebral palsy, autism spectrum disorder or attention deficit hyperactivity disorder (ADHD), etc.;\n3. Patients with severe liver dysfunction (Child-Pugh C grade);\n4. Patients with severe kidney dysfunction (requiring dialysis before surgery);\n5. Patients with a history of congenital heart disease requiring surgery or drug treatment;\n6. Those allergic to the study drugs remimazolam or propofol;\n7. Any known neural damage, such as cystic periventricular leukomalacia or grade 3 or 4 intraventricular hemorrhage;\n8. Social or geographical factors that may lead to postoperative loss of follow-up;\n9. Planned to undergo two surgeries within 7 days after the surgery;\n10. Those currently participating in other clinical trials;\n11. Those receiving special care or living in social welfare institutions or any other factors that may affect their ability to participate in the study.","6 Years",{"count":90,"type":21},558,[92],"PHASE4","The goal of this clinical trial is to learn the effects of remimazolam for total intravenous anesthesia on the neurodevelopment of children aged 3-6 years who underwent tonsil\u002Fadenoid removal surgery after general anesthesia when compared with propofol. It will also learn about the safety of remimazolam used for children. The main questions it aims to answer are:\n\n* Does remimazolam improve the postoperative neurodevelopmental outcomes of the children after general anesthesia compared with propofol?\n* What medical problems do participants have when receive remimazolam for general anesthesia? Researchers will compare remimazolam to propofol to see if remimazolam improve the postoperative neurodevelopmental outcomes of the children after general anesthesia.\n\nParticipants will:\n\n* Receive remimazolam or propofol for general anesthesia induction and maintenance\n* At 1-3 years after the surgery, the Wechsler Preschool and Primary Scale of Intelligence - Fourth Edition was used for face-to-face assessment of the children's neurodevelopmental status.\n* Use scales such as BRIEF-P and CBCL to conduct face-to-face assessments of the patient's cognitive functions in other areas.",[27],[96,97,98,99,100],"remimazolam","neurodevelopment","propofol","children","tonsillectomy","NOT_YET_RECRUITING","2025-09-25",{"date":104,"type":33},"2025-09-26",{"date":106,"type":21},"2025-10-01",{"date":108,"type":21},"2030-10-01",{"name":110,"class":80},"The First Affiliated Hospital of Anhui Medical University",{"id":112,"slug":113,"hasResults":11,"nctId":114,"briefTitle":115,"officialTitle":116,"acronym":4,"eligibilityCriteria":117,"healthyVolunteers":118,"sex":16,"minAge":4,"maxAge":119,"enrollmentInfo":120,"targetDuration":4,"studyType":22,"phases":122,"briefSummary":123,"conditions":124,"keywords":125,"overallStatus":101,"whyStopped":4,"lastUpdateSubmitDate":130,"lastUpdatePostDateStruct":131,"startDateStruct":133,"completionDateStruct":135,"leadSponsor":137,"locationsCount":41},"100592078","diet-education-and-postoperative-outcomes-in-pediatric-adenotonsillectomy-100592078","NCT06988748","Diet Education and Postoperative Outcomes in Pediatric Adenotonsillectomy","The Effect of Tonsillectomy Diet Education on Bleeding and Pain After Adenotonsillectomy in Children","Inclusion Criteria:\n\n* The child being sick,\n* The child will have an adenotonsillectomy,\n* The child has no milk allergy (to exclude children at risk of developing milk allergy during the data collection process),\n* The child's caregiver stays with the child during the research process (to avoid communication barriers and disruptions in treatment and care instructions during the training and data collection process),\n* The child and caregiver can speak and understand Turkish (to avoid communication barriers during the training and data collection process),\n* The child's caregiver agrees to the research,\n* Children without swallowing difficulties and aspiration risk (e.g. nasogastric catheter, tracheostomy)\n* Children without diseases that cause maladaptive behavior (e.g. autism, cerebral palsy)\n\nExclusion Criteria:\n\n* The child has a milk allergy,\n* Children with diseases that cause swallowing difficulties, risk of aspiration and maladaptive behavior (e.g. autism, cerebral palsy)\n* Failure of the child and caregiver to attend the follow-up examination on the 7th day after surgery",true,"18 Years",{"count":121,"type":21},76,[24],"This randomized controlled trial aims to evaluate the effect of tonsillectomy diet education on postoperative bleeding and pain in children undergoing adenotonsillectomy. Seventy-six pediatric patients will be randomly assigned to either an intervention group, which will receive specific diet education prior to surgery, or a control group receiving standard care. Bleeding and pain will be assessed at 4, 8, and 24 hours, and on the 7th day after surgery using a specialized follow-up form and the Wong-Baker Faces Pain Rating Scale. The study hypothesizes that diet education will reduce postoperative bleeding and pain, improving recovery and quality of life in children.",[27],[69,126,127,128,129,28],"Child","Diet Education","Tonsillectomy Diet","Postoperative Bleeding","2025-05-30",{"date":132,"type":33},"2025-06-04",{"date":134,"type":21},"2025-06-20",{"date":136,"type":21},"2026-10-31",{"name":138,"class":80},"Maltepe University",{"id":140,"slug":141,"hasResults":11,"nctId":142,"briefTitle":143,"officialTitle":143,"acronym":144,"eligibilityCriteria":145,"healthyVolunteers":11,"sex":16,"minAge":146,"maxAge":147,"enrollmentInfo":148,"targetDuration":4,"studyType":22,"phases":150,"briefSummary":151,"conditions":152,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":155,"lastUpdatePostDateStruct":156,"startDateStruct":158,"completionDateStruct":160,"leadSponsor":162,"locationsCount":41},"100564829","comparison-of-two-reeducation-methods-in-children-with-persistent-sleep-apnea-a-randomized-controlled-trial-100564829","NCT06634264","Comparison of Two Reeducation Methods in Children With Persistent Sleep Apnea, a Randomized Controlled Trial","PERSIST-B-RCT","Inclusion Criteria:\n\nparticipants must:\n\n* present signs of obstructive sleep apnea: snoring, apnea \u002F respiratory pauses audible by the entourage (objectivized by a score, to the Pediatric Sleep Questionnaire (PSQ) , greater than or equal to 0.33- This questionnaire comprises twenty-two Questions and has a good sensitivity (83%) and specificity (87%) in screening for pediatric sleep apnea.\n* be programmed for adenoidectomy, tonsillectomy or adeno-tonsillectomy within 3 months (or more).\n\nExclusion Criteria:\n\nparticipants should not:\n\n* present with a craniofacial syndrome nor a severe medical condition with complex medical management,\n* present with an abnormality of the neuromuscular tone (such as Duchenne myopathy or cerebral palsy)\n* receive orthodontic therapy during the study\n* have a class III malocclusion (mandibular prognathy type), for which a propulsion oral appliance is contraindicated because it may aggravate mandibular prominence. Maxillary deficiency is not a exclusion criterion.\n* A non-nutritive oral habit such as digital sucking (or pacifier) that persists because it interferes with oral reeducation and is a contraindication to orthodontic treatments. Children who have recently stopped such a habit may be included in the study.","4 Years","14 Years",{"count":149,"type":21},60,[24],"Myofunctional therapy has been shown to be effectively reduce symptoms of paediatric obstructive sleep apnea, usually performed after adenotonsillectomy.\n\nThis study aims to evaluate the effectiveness of Passive Oral Myofunctional Reeducation (using a flexible oral appliance) compared to nasal hygiene alone (control group), in a population of children scheduled for adenotonsillectomy.",[153,154,27],"Obstructive Sleep Apnea of Child","Sleep-Disordered Breathing","2024-10-07",{"date":157,"type":33},"2024-10-09",{"date":159,"type":33},"2024-03-20",{"date":161,"type":21},"2027-03-31",{"name":163,"class":80},"Université de Montréal"]