[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"adhesion-uterus-internal\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:adhesion-uterus-internal":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":4},"100614491","incidence-of-intrauterine-adhesions-after-myomectomy-with-intrauterine-anti-adhesion-gel-100614491",false,"NCT07280286","Incidence of Intrauterine Adhesions After Myomectomy With Intrauterine Anti-Adhesion Gel","Incidence of Intrauterine Adhesions Following Myomectomies With the Use of an Intrauterine Anti-adhesion Gel","Inclusion Criteria:\n\n* Age between 18 and 45 years;\n* BMI 18-35;\n* One or more fibroids diagnosed via ultrasound;\n* First myomectomy or uterine surgery;\n* Incomplete reproductive plans and\u002For infertility;\n* Adequate immune, respiratory, liver, cardiac, bone marrow, and kidney function;\n* Compliance and psychological ability to follow study procedures;\n* Acceptance and signing of informed consent.\n\nExclusion Criteria:\n\n* Age under 18 years;\n* Age over 46 years;\n* Pregnancy or breastfeeding;\n* History of intrauterine adhesions;\n* Diagnosis or suspicion of malignant gynecological pathologies and\u002For autoimmune diseases;\n* Completed reproductive plans;\n* Severe respiratory, bone marrow, liver, or kidney dysfunction preventing safe surgical access.","FEMALE","18 Years","45 Years",{"count":20,"type":21},62,"ESTIMATED","INTERVENTIONAL",[24],"NA","This prospective randomized study aims to evaluate whether the application of an intrauterine anti-adhesion gel reduces the incidence of intrauterine adhesions (IUAs) following robotic-assisted laparoscopic myomectomy. Intrauterine adhesions may develop after endometrial trauma during surgery and can negatively affect menstrual function, fertility, and future pregnancy outcomes. Robotic myomectomy offers a minimally invasive approach, but postoperative adhesion formation remains a concern.\n\nSixty-two women undergoing myomectomy will be randomized to receive either intrauterine anti-adhesion gel (intervention group) or no adhesion-prevention method (control group). Adhesions will be assessed by ultrasound and hysteroscopy during follow-up. Secondary outcomes include reproductive results over a 24-month period, such as implantation rate, clinical pregnancy, miscarriage, live birth, pregnancy complications, and neonatal outcomes.\n\nThe study seeks to determine whether combining a minimally invasive surgical approach with an intrauterine gel provides additional protection against adhesion formation and improves fertility-related outcomes.",[27,28],"Myoma;Uterus","Adhesion; Uterus, Internal",[30,31],"intrauterine adhesions","myomectomy","NOT_YET_RECRUITING","2025-12-03",{"date":35,"type":36},"2025-12-12","ACTUAL",{"date":38,"type":21},"2025-12-09",{"date":40,"type":21},"2028-11-20",{"name":42,"class":43},"Federico II University","OTHER"]