[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"adhesive-capsulitis-of-shoulder\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:adhesive-capsulitis-of-shoulder":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,44,77,106,127],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":26,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100632412","investigation-of-the-effectiveness-of-exercise-and-anti-fibrotic-approaches-in-frozen-shoulder-100632412",false,"NCT07513350","Investigation of the Effectiveness of Exercise and Anti-Fibrotic Approaches in Frozen Shoulder","Inclusion Criteria:\n\n* Adults aged 18 years or older diagnosed with frozen shoulder (adhesive capsulitis)\n* Having less than 50% of range of motion (ROM) in at least one of the following shoulder movements compared to the unaffected side: external rotation, abduction, flexion, or internal rotation\n* Having more than 25% loss of ROM in at least two movement planes compared to the unaffected shoulder\n* Patients in stage II or III of frozen shoulder\n\nExclusion Criteria:\n\n* Women who are pregnant, breastfeeding, or planning pregnancy during the study\n* Patients in stage I of frozen shoulder\n* Patients diagnosed with inflammatory or other types of arthritis due to autoimmune diseases affecting the shoulder\n* Patients with rotator cuff pathology and\u002For glenohumeral arthritis\n* Patients with a history of prior shoulder infection\n* Patients with hypotension\n* Patients who have undergone previous upper extremity surgery or plan to undergo upper extremity surgery during the study period\n* Patients with allergy to losartan or its active\u002Finactive components\n* Patients taking medications known to have adverse interactions with losartan\n* Patients who, in the investigator's opinion, have any medical condition, laboratory abnormality, or history that could pose risk, contraindicate participation, affect the conduct, objectives, or evaluation of the study, or prevent full participation in the study","ALL","18 Years",{"count":18,"type":19},33,"ESTIMATED","INTERVENTIONAL",[22],"NA","The purpose of this clinical study is to investigate the efficacy of losartan as an antifibrotic approach in addition to a physiotherapy program in patients diagnosed with frozen shoulder. The effects of losartan use on pain intensity, shoulder joint range of motion, functional status, and pain catastrophizing level will be evaluated and compared with the outcomes of patients participating in a physiotherapy program alone.\n\nThe key questions this study aims to answer are:\n\n* Is there a difference in shoulder functionality between frozen shoulder patients using losartan in addition to a physiotherapy program and those participating in a physiotherapy program alone?\n* Is there a difference in pain intensity, shoulder joint range of motion, and pain catastrophizing level between frozen shoulder patients using losartan in addition to a physiotherapy program and those participating in a physiotherapy program alone? A total of 33 patients will be enrolled in the study. Participants will be randomly assigned to one of two groups: the physiotherapy group (PT) and the physiotherapy + losartan group (PT+L). Both groups will receive the same physiotherapy program comprising range of motion exercises, stretching exercises, strengthening exercises, and mobilization techniques. Patients in the PT+L group will additionally receive 12.5 mg of oral losartan once daily for four weeks. Clinical assessments will be conducted at baseline, at week 4, and at week 8.",[25],"Adhesive Capsulitis of Shoulder",[27,28,29,30],"Frozen shoulder","Exercise therapy","Losartan","Shoulder pain","RECRUITING","2026-04-01",{"date":34,"type":35},"2026-04-07","ACTUAL",{"date":37,"type":35},"2026-01-07",{"date":39,"type":19},"2027-01",{"name":41,"class":42},"Istanbul University","OTHER",1,{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":48,"acronym":4,"eligibilityCriteria":49,"healthyVolunteers":11,"sex":15,"minAge":50,"maxAge":51,"enrollmentInfo":52,"targetDuration":4,"studyType":20,"phases":54,"briefSummary":55,"conditions":56,"keywords":59,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":43},"100620386","the-combined-effect-of-mulligan-technique-and-scapular-mobilization-in-shoulder-adhesive-capsulitis-100620386","NCT07356947","The Combined Effect of Mulligan Technique and Scapular Mobilization in Shoulder Adhesive Capsulitis","Inclusion Criteria:\n\n* Medically stable and willing to provide informed consent to participate in the study.\n* Age between 30 and 60 years.\n* Both male and female participants.\n* Unilateral shoulder involvement with pain and limited active and passive range of motion in lateral rotation, abduction, and internal rotation for more than three months compared with the unaffected side.\n* Clinically diagnosed with adhesive capsulitis (frozen shoulder).\n\nExclusion Criteria:\n\n* History of shoulder surgery.\n* History of radiotherapy or chemotherapy.\n* Presence of acute infection in the area to be treated.\n* History of skin disease.\n* History of cervical radiculopathy within the past six months.\n* Secondary adhesive capsulitis, rotator cuff tears, shoulder fractures, or dislocations.","30 Years","60 Years",{"count":53,"type":19},38,[22],"The shoulder joint capsule is a fibrous sheath that encloses and stabilizes the structures of the shoulder joint, extending from the anatomical neck of the humerus to the rim of the glenoid fossa. It is normally lax, allowing a wide range of motion. Shoulder adhesive capsulitis, or frozen shoulder, is a common musculoskeletal condition characterized by pain and restricted movement due to thickening and contraction of this capsule. Proper coordination between the scapula and humerus-known as the scapulohumeral rhythm-is essential for normal shoulder motion. Disruption of this rhythm contributes to movement limitation and pain in adhesive capsulitis.\n\nThis randomized, single-blind clinical trial aims to investigate the combined effect of the Mulligan technique and scapular mobilization on improving shoulder range of motion, pain, disability, and scapulohumeral rhythm in patients with adhesive capsulitis. Thirty-eight participants aged 30 to 60 years, diagnosed with unilateral adhesive capsulitis, will be randomly assigned to two groups. Group A will receive Mulligan mobilization techniques for shoulder elevation, internal and external rotation, along with scapular mobilization. Group B will receive conventional physical therapy consisting of hot packs, ultrasound, stretching, and range-of-motion exercises. Both groups will undergo treatment three times per week for four weeks.\n\nPrimary outcomes include changes in shoulder range of motion (measured using a digital goniometer), pain and disability (measured by the Shoulder Pain and Disability Index \\[SPADI\\]), and scapulohumeral rhythm (assessed using tape measurement). The study is expected to provide clinical evidence on whether combining Mulligan and scapular mobilization techniques yields superior functional recovery compared with conventional physiotherapy alone in patients with shoulder adhesive capsulitis.",[25,57,58],"Frozen Shoulder","Shoulder Pain and Stiffness",[60,57,61,62,63,64,65,66],"Adhesive Capsulitis","Shoulder Joint","Shoulder Pain","Scapulohumeral Rhythm","Mulligan Technique","Mobilization with Movement","Scapular Mobilization","NOT_YET_RECRUITING","2026-01-27",{"date":70,"type":35},"2026-01-28",{"date":72,"type":19},"2026-02",{"date":74,"type":19},"2027-08",{"name":76,"class":42},"Deraya University",{"id":78,"slug":79,"hasResults":11,"nctId":80,"briefTitle":81,"officialTitle":82,"acronym":4,"eligibilityCriteria":83,"healthyVolunteers":84,"sex":15,"minAge":16,"maxAge":85,"enrollmentInfo":86,"targetDuration":4,"studyType":20,"phases":88,"briefSummary":89,"conditions":90,"keywords":91,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":100,"completionDateStruct":102,"leadSponsor":104,"locationsCount":4},"100553752","shock-wave-therapy-as-a-treatment-intervention-for-frozen-shoulder-100553752","NCT06490172","Shock Wave Therapy as a Treatment Intervention for Frozen Shoulder","The Effects of Extracorporeal Shock Wave Therapy as a Treatment Intervention for Chronic Adhesive Capsulitis: a Mixed Methods Pilot Study","Inclusion Criteria:\n\n1. Participants aged 18 years and older.\n2. Diagnosis of primary or secondary shoulder AC of a greater than three-month duration.\n3. Diagnosis of AC by an orthopaedic consultant or upper limb Advanced Practice Physiotherapist.\n4. Participants can attend an outpatient rural physiotherapy department to receive shockwave therapy intervention.\n5. They understand English.\n\nExclusion Criteria:\n\n1. Participants who have bilateral shoulder pain, capsular tightness, calcific rotator cuff tendinitis, rotator cuff tear (atraumatic or traumatic), previous surgery on the affected shoulder, shoulder fracture, dislocation or subluxation, glenohumeral or acromioclavicular arthritis, malignancy, inflammatory disorders, neuromuscular disorders, presence of severe osteoporosis, pulmonary diseases, implanted pacemaker and pregnancy.\n2. They have conditions related to ESWT contraindications (e.g., pregnancy, pacemaker, metal work or joint replacement near the treatment site, blood clotting disorder, use of anti-coagulants, less than six weeks of receiving a steroid injection over treatment site, malignancy, local infection or open wounds, skeletal growth places, under 18 years old).\n3. Symptom duration less than 12 weeks.\n4. Absent or altered skin sensation.\n5. They are unable to give full informed consent.",true,"70 Years",{"count":87,"type":19},18,[22],"Adhesive capsulitis (AC) is a debilitating condition that causes global restriction and pain at the glenohumeral joint. Physiotherapy treatment is often first line treatment management. Patients with failed conservative management are commonly referred to a specialist consultant for further treatment. Over the last 20 years, extracorporeal shock wave therapy (ESWT) has gained popularity as a treatment for various orthopaedic presentations, including chronic soft tissue conditions, being non-invasive, resulting in good outcomes with minimal side effects. There is a lack of evidence on the clinical effectiveness of ESWT for chronic AC following failed conservative treatments, with the available literature reporting positive outcomes, however, with heterogeneity in treatment protocols. This proposed study aims to explore the feasibility of a full trial of ESWT as a treatment for AC using a standardised treatment protocol, and clinical effects on outcomes of pain, function and shoulder joint range of movement in persons with chronic adhesive capsulitis.\n\nA Delphi study will first explore expert opinion for the optimum treatment protocol of ESWT as a treatment for chronic AC, followed by a mixed methods explanatory sequential study that includes a pilot trial with nested qualitative interviews. The Shoulder Pain and Disability Index, numerical pain rating scale, EuroQol-5D, and digital goniometer will be used to measure self-reported pain and function, pain, health-related quality of life, and shoulder joint range of movement, respectively. Quantitative data will be analysed by descriptive statistics. Qualitative data will be collected through semi-structured interviews. Interview data will be analysed using Braun and Clarke's inductive thematic analysis approach. The study will be conducted in an out-patient clinical setting in a community health hub facility, with patients recruited from an NHS Orthopaedics waitlist. Data collection is planned over a nine month period. This study is not affiliated with funding streams.",[62,25],[92,93,94,95,96,97],"shock wave therapy","frozen shoulder","adhesive capsulitis","shoulder pain","physiotherapy","lithotripsy","2026-01-23",{"date":68,"type":35},{"date":101,"type":19},"2026-05",{"date":103,"type":19},"2027-04",{"name":105,"class":42},"University of Stirling",{"id":107,"slug":108,"hasResults":11,"nctId":109,"briefTitle":110,"officialTitle":111,"acronym":4,"eligibilityCriteria":112,"healthyVolunteers":84,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":113,"targetDuration":4,"studyType":20,"phases":115,"briefSummary":116,"conditions":117,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":118,"lastUpdatePostDateStruct":119,"startDateStruct":121,"completionDateStruct":123,"leadSponsor":125,"locationsCount":43},"100468769","outcomes-of-treatment-using-the-ermi-shoulder-flexionater--100468769","NCT05384093","Outcomes of Treatment Using the ERMI Shoulder Flexionater ®","Outcomes of Treatment Using the ERMI Shoulder Flexionater®","For Study Group 1- Adhesive Capsulitis (AC)\n\nInclusion Criteria:\n\n* Exhibits symptoms of adhesive capsulitis i. Shoulder pain with limited motion for more than one month ii. AND ≤ 30 degrees external rotation with arm at side iii. AND ≤ 130 degrees forward flexion d. Cortisone shot for all patients\n\nExclusion Criteria:\n\n* a. No prior shoulder surgery b. Infection c. Rheumatoid arthritis d. Any structural or systemic disorder that could result in pain or ROM limitation i. Such as inflammatory joint disease, osteoarthritis evidenced on radiographs ii. full thickness rotator cuff tear as shown by ultrasound imaging iii. history of major trauma or surgery involving the shoulder\n\nFor Study Group 2 - Postoperative Shoulder Stiffness Study (POS)\n\nInclusion Criteria:\n\nc. Is not recovering normally based on objective criteria set for screening process i. Step 1 - Follow patients -all post-op patients with indicated procedures (see # 7 for list.) ii. Step 2 - Screen Patients -does patient meets inclusion criteria at 6 weeks or 3 months of follow-up?\n\n1. \\\u003C 15 degrees external rotation with arm at side at 6 weeks post-op\n2. OR \\\u003C 90 degrees forward flexion at 3 months post-op iii. Step 3 - Enroll patients that meet inclusion criteria and assign group\n\nExclusion Criteria:\n\na. Revision surgery b. Infection c. Rheumatoid arthritis\n\n7\\. Procedures included\n\n1. Shoulder arthroscopic procedures (29827, 29828, 29823,29824, 29826)\n2. ORIF Humerus fracture (23615)\n\n   For Study Group 3, Secondary Surgery Study (SAM)\n\n   Inclusion Criteria:\n3. Underwent a manipulation under anesthesia or a lysis of adhesions procedure\n\nExclusion Criteria:\n\na. Infection b. Rheumatoid arthritis c. Any structural or systemic disorder that could result in pain or ROM limitation i. Such as inflammatory joint disease, osteoarthritis evidenced on radiographs ii. full thickness rotator cuff tear as shown by ultrasound imaging iii. history of major trauma or surgery involving the shoulder\n\n7\\. Procedures included\n\n1. Manipulation under anesthesia (23700)\n2. Lysis of adhesions (29825)",{"count":114,"type":19},210,[22],"Study 1 - Adhesive Capsulitis Study - 110 patients The purpose of this study is to compare treatment of patients with symptoms of adhesive capsulitis, primary and secondary, between three groups: I) Physical Therapy alone; II) ERMI Shoulder Flexionater® alone; III) PT + Device.\n\nStudy 2 - Postoperative Shoulder Stiffness Study - 90 patients The purpose of this study is to compare treatment of patients with post-operative stiffness indicative of secondary adhesive capsulitis between three groups: I) Physical Therapy alone; II) ERMI Shoulder Flexionater® alone; III) PT + Device.\n\nStudy 3 - Stiffness after MUA Study - enroll all eligible patients (goal of at least 15) The purpose of this study is to compare treatment of patients who have undergone manipulation under anesthesia or lysis of adhesions between three groups: I) Physical Therapy alone; II) ERMI Shoulder Flexionater® alone; III) PT + Device.",[25],"2025-08-04",{"date":120,"type":35},"2025-08-07",{"date":122,"type":35},"2019-06-25",{"date":124,"type":19},"2026-06-25",{"name":126,"class":42},"Foundation for Orthopaedic Research and Education",{"id":128,"slug":129,"hasResults":11,"nctId":130,"briefTitle":131,"officialTitle":132,"acronym":4,"eligibilityCriteria":133,"healthyVolunteers":11,"sex":15,"minAge":134,"maxAge":135,"enrollmentInfo":136,"targetDuration":4,"studyType":20,"phases":138,"briefSummary":139,"conditions":140,"keywords":141,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":145,"lastUpdatePostDateStruct":146,"startDateStruct":148,"completionDateStruct":150,"leadSponsor":152,"locationsCount":43},"100568826","effects-of-gongs-versus-mulligan-mobilization-in-patients-with-adhesive-capsulitis-100568826","NCT06686277","Effects Of Gong's Versus Mulligan Mobilization In Patients With Adhesive Capsulitis","Effects Of Gong's Versus Mulligan Mobilization On Pain, Range Of Motion, Functional Disability and Quality Of Life In Patients With Adhesive Capsulitis","Inclusion Criteria:\n\n* Age 40 to 50 years\n* Both male and female\n* Pre-diagnosed Unilateral Primary Frozen shoulder patients\n* Prediagnosed Stage 3(Frozen phase) patients(27)\n\nExclusion Criteria:\n\n* Patients with previous surgery in the shoulder joint\n* History of recent fracture or severe trauma to the shoulder\n* Diagnosed instability or previous history of dislocation\n* Systemic inflammatory conditions(e.g.rheumatoid arthritis)","40 Years","50 Years",{"count":137,"type":19},60,[22],"A Randomized Clinical Trial will be conducted at DHQ hospital kasur,BIT hospital kasur,Arif memorial hospital Lahore.Pre-diagnosed patients will be reassessed by applying (Shoulder Shrug Sign, Hand to neck, Hand to scapula, Hand to opposite scapula,Hand to back,Capsular pattern movement restriction)Plus all other special tests will be applied to confirm that symptoms are not due to other shoulder pathologies but are due to just adhesive capsulitis then through consecutive sampling technique on 60 patients they will be allocated using computer generated sampling(random number table) into Group A and Group B.",[25],[142,143,144],"Adhesive capsulitis","Functional Disability","Range of Motion","2024-11-12",{"date":147,"type":35},"2024-11-13",{"date":149,"type":35},"2024-04-24",{"date":151,"type":19},"2025-02-24",{"name":153,"class":42},"Riphah International University"]