[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"adolescent-alcohol-use\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:adolescent-alcohol-use":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,40,77],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":4},"100644268","hybrid-type-1-trial-of-a-parent-based-intervention-addressing-social-media-and-adolescent-alcohol-use-100644268",false,"NCT07664644","Hybrid Type 1 Trial of a Parent-Based Intervention Addressing Social Media and Adolescent Alcohol Use","A Hybrid Type 1 Effectiveness Implementation Trial of a Parent-Based Intervention to Address Social Media Influences on Adolescent Alcohol Outcomes","Parents\u002Flegal guardian inclusion criteria:\n\n* Have a child between the ages of 12-17 who lives with them\n* Believe that their child is active on at least one social media platform\n* Live in Texas\n* Provide a valid email and phone number\n* Own a cell phone with text messaging capabilities and be okay with receiving messages\n* Provide valid contact information for their adolescent\n* Willing to participate in respective phase.\n\nAdolescent inclusion criteria:\n\n* Have an eligible parent with whom they live\n* Age 12-17\n* Live in Texas\n* Active at least weekly on at least one social media platform\n* Provide a valid phone number and email address\n* Own a cell phone with text messaging capabilities and be okay with receiving text messages,\n* Willing to participate in respective phase",true,"ALL","12 Years",{"count":20,"type":21},900,"ESTIMATED","INTERVENTIONAL",[24],"NA","The central goal of this application is to conduct a Hybrid Type 1 effectiveness-implementation randomized controlled trial to test the comparative effectiveness of an alcohol and social media parent-based intervention (PBI), compared to both a combined approach whereby parents receive the alcohol and social media PBI and adolescents receive an alcohol and social media personalized feedback intervention (PFI) and to an efficacious alcohol PBI handbook. Additionally, we will determine key implementation determinants that are crucial to optimizing effectiveness when delivered in community settings. The proposed study will address each of these goals in turn by enrolling parent and adolescent (age 12-17) dyads and collaborating with key community members.",[27],"Adolescent Alcohol Use","NOT_YET_RECRUITING","2026-06-18",{"date":31,"type":32},"2026-06-24","ACTUAL",{"date":34,"type":21},"2027-07",{"date":36,"type":21},"2030-08",{"name":38,"class":39},"The University of Texas at Arlington","OTHER",{"id":41,"slug":42,"hasResults":11,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":46,"eligibilityCriteria":47,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":48,"enrollmentInfo":49,"targetDuration":4,"studyType":22,"phases":51,"briefSummary":52,"conditions":53,"keywords":54,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":76},"100597483","brief-motivational-interviewing---mindfulness-training-for-adolescent-alcohol-use-in-pediatric-primary-care-100597483","NCT07059078","Brief Motivational Interviewing +\u002F- Mindfulness Training for Adolescent Alcohol Use in Pediatric Primary Care","PCORI Comparative Effectiveness Study: Comparative Effectiveness of Brief Motivational Interviewing +\u002F- Adjunctive Smartphone App-delivered Mindfulness Training for Reducing Alcohol Use in Adolescents in Pediatric Primary Care Settings","PCORIMINDSET","Inclusion Criteria:\n\n* 12-17 years old\n* Receiving pediatric primary care (PPC) services through the Johns Hopkins Medical Institute healthcare network\n* Screening positive for moderate or high alcohol use risk as indicated by a S2BI score (i.e., showing any monthly alcohol use in the past 12 months)\n* Able to speak, understand, and read in English or Spanish\n* Able to provide assent, and receiving parental consent\u002Fpermission to participate.\n\nExclusion Criteria:\n\n* Severe medical or psychiatric condition (e.g., behavioral dysregulation, psychopathology, or cognitive impairment that in the judgement of study or PPC provider may make participation hazardous \\[e.g., psychosis, homicidality, active suicidality, mania\\])\n* Intellectual Disability (self-, caregiver-, or PPC-reported, or PPC-documented)\n* Current or recent specialty substance use disorder treatment in the past 6 months\n* Demonstrated current physiological alcohol withdrawal requiring urgent inpatient referral in the judgement of study or PPC physician\n* Reported regular opioid, benzodiazepine, or cocaine use (\\> weekly) or history of opioid, benzodiazepine, or cocaine overdose in the past 6 months\n* Previous experience with a mindfulness-based intervention in the past 12 months\n* Current regular meditation practice (\\> 30 min\u002Fday for \\> 5 days avg. over 30 days prior to screening).","17 Years",{"count":50,"type":21},1500,[24],"Alcohol use is prevalent in U.S. adolescents and contributes to adverse health outcomes in this population. Care for adolescent alcohol use is lacking in most pediatric primary care settings (PPC). This project is a pragmatic comparative effectiveness and implementation study that employs a superiority, two-arm, randomized, prospective, observer-blinded, controlled trial design to compare the effectiveness of a patient-centered brief motivational interviewing-based alcohol intervention (BMAI) alone to the same BMAI augmented with adjunctive smartphone app-delivered mindfulness training (MT) for alcohol use in adolescents receiving primary care in PPC clinics across a regional health network. Main effectiveness outcomes will be alcohol use and alcohol related problems assessed over a one-year follow-up period. Implementation outcomes and mediators and moderators of intervention response will also be examined as part of the study.",[27],[55,56,57,58,59,60,61,62,63,64,65],"Alcohol use","Alcohol-related problems","Drug use","Adolescent","Motivational interviewing","Mindfulness","Mindfulness training","brief alcohol intervention","digital therapeutic intervention","SBIRT","PCORI","RECRUITING","2025-09-15",{"date":69,"type":32},"2025-09-16",{"date":71,"type":32},"2025-09-03",{"date":73,"type":21},"2030-09-30",{"name":75,"class":39},"Johns Hopkins University",13,{"id":78,"slug":79,"hasResults":11,"nctId":80,"briefTitle":81,"officialTitle":82,"acronym":4,"eligibilityCriteria":83,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":48,"enrollmentInfo":84,"targetDuration":4,"studyType":22,"phases":86,"briefSummary":87,"conditions":88,"keywords":92,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":103,"locationsCount":105},"100553484","centralized-virtual-sbirt-for-pediatric-primary-care-100553484","NCT06486688","Centralized Virtual SBIRT for Pediatric Primary Care","Virtual SBIRT for Pediatric Primary Care: Increasing Access to Screening, Brief Intervention and Referral to Treatment for Alcohol and Other Drug Use Via Telehealth","Inclusion Criteria:\n\n• The sample will include all adolescents aged 12 through 17 years seen for a Well Visit, who are at risk of AOD use disorder defined as endorsing monthly or more frequent AOD use OR any AOD use and past-two-week depressive symptoms or suicidality.\n\nExclusion Criteria:\n\n• N\u002FA - all adolescents with a Well Visit are eligible",{"count":85,"type":21},22320,[24],"Adolescent alcohol and other drug (AOD) use is a significant public health problem which contributes to high levels of mortality, morbidity and healthcare costs in young people, and identification and early intervention for these problems is critical to improving outcomes. Screening, Brief Intervention and Referral to Treatment (SBIRT) in pediatric primary care is an evidence-based strategy for addressing these problems, but has not been widely and systematically implemented, for a variety of reasons, including lack of training and staffing resources to support its implementation. This pragmatic, Type 1 Hybrid Comparative Effectiveness Implementation study will examine whether a centralized, virtually-delivered modality of SBIRT, rapidly accessible by multiple pediatric primary care clinics, can be cost-effectively implemented to improve early identification and treatment for AOD use and comorbid mental health problems among adolescents identified as being at high or severe risk of AOD use disorder during adolescent Well Visits.",[27,89,90,91],"Mental Health Issue","Alcohol Related Disorders","Adolescents",[91,93,64,94,95],"Alcohol","Screening","Drug","2024-07-04",{"date":98,"type":32},"2024-07-08",{"date":100,"type":32},"2024-02-13",{"date":102,"type":21},"2027-08-31",{"name":104,"class":39},"Kaiser Permanente",1]