[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"adolescent-and-young-adult-cancer\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:adolescent-and-young-adult-cancer":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,48],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100629208","family-building-decision-support-for-female-adolescent-and-young-adult-cancer-survivors-100629208",false,"NCT07471685","Family Building Decision Support for Female Adolescent and Young Adult Cancer Survivors","Development and Pilot Testing of a Family Building Decision Support Intervention for Female Adolescent and Young Adult Cancer Survivors","Inclusion Criteria:\n\n* Female (biological sex) AYA cancer survivor age 15-39 at original diagnosis and 18-39 at enrollment.\n* Completed cancer treatment with curative intent.\n* Prior exposure to treatments posing gonadotoxic risk (e.g., alkylating agents, total body irradiation) and\u002For treatments increasing obstetric risk (e.g., chest radiation, radiation to uterus, anthracycline exposure).\n* Has not completed family building.\n* Able to speak\u002Fread English.\n* Willing and able to complete videoconference sessions and REDCap surveys.\n\nExclusion Criteria:\n\n* Visual, hearing, or cognitive impairment or severe mental illness that would interfere with participation as determined by study staff.","FEMALE","18 Years","39 Years",{"count":20,"type":21},48,"ESTIMATED","INTERVENTIONAL",[24],"NA","This study aims to develop and pilot-test a nurse navigator-delivered behavioral program to support female adolescent and young adult (AYA) cancer survivors in making informed, values-driven family-building decisions after completion of cancer treatment. Female AYA survivors often face fertility impairments, uncertainty about reproductive potential, elevated obstetric risks during pregnancy, and significant emotional distress related to parenthood planning. Currently, few interventions address these post-treatment decision-making needs.\n\nThe intervention consists of four videoconference sessions that combine personalized, risk-based reproductive health education with coping strategies derived from Acceptance and Commitment Therapy and Patient Activation Theory. A pilot randomized controlled trial will evaluate feasibility, acceptability, and preliminary changes in knowledge, decisional conflict, self-efficacy, and reproductive-health-related distress among 48 participants randomized to the intervention or a survivorship-education control condition. Findings will inform future testing of the intervention's efficacy in a larger clinical trial.",[27,28,29],"Cancer Survivorship","Family Planning","Adolescent and Young Adult Cancer",[31,32,33,34],"AYA","oncofertility","fertility after cancer","survivorship","RECRUITING","2026-05-12",{"date":38,"type":39},"2026-05-14","ACTUAL",{"date":41,"type":39},"2026-05-11",{"date":43,"type":21},"2026-12",{"name":45,"class":46},"Duke University","OTHER",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":4,"eligibilityCriteria":54,"healthyVolunteers":11,"sex":55,"minAge":56,"maxAge":57,"enrollmentInfo":58,"targetDuration":4,"studyType":22,"phases":60,"briefSummary":61,"conditions":62,"keywords":64,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":47},"100591564","improving-communication-between-aya-oncology-patients-and-clinicians-a-patient-centered-intervention-100591564","NCT06982066","Improving Communication Between AYA Oncology Patients and Clinicians: A Patient-Centered Intervention","Improving Health-Related Quality of Life Communication Between AYA Oncology Patients and Clinicians: A Patient-Centered Intervention","Inclusion Criteria\n\nAdolescent and Young Adult Oncology Patients\n\nIn order to be eligible to participate in this study, an individual must meet all of the following criteria:\n\n1. Be aged 15-25 years old at time of enrollment.\n2. Have a cancer diagnosis and currently be on cancer-directed therapy with at least one of the following:\n\n   1. Chemotherapy: any anticancer drug to treat the cancer diagnosis, including immunotherapy.\n   2. Radiotherapy: any radiotherapy to treat the cancer diagnosis.\n   3. Surgery: any surgery to remove cancer including partial of total resections. Biopsies are not considered surgery.\n3. Be greater than or equal to 2 months from diagnosis\u002Finitiation of therapy, whichever occurred later.\n4. Be able to speak and read English\n5. Have permission to participate from a member of the patient's primary oncology team.\n6. Provision to sign and date the consent\u002Fassent form.\n7. Active study participation of primary oncology clinician\n8. Patient must have primary oncology care at Connecticut Children's Center for Cancer \\& Blood Disorders of Children's Hospital Los Angeles Cancer \\& Blood Disease Institute\n\nExclusion Criteria\n\nAn individual who meets and of the following criteria will be excluded from participation in this study:\n\n1. Not currently on cancer-directed therapy.\n2. Unable to speak and read English.\n3. Insufficient cognitive functioning to complete study measures (as determined by a member of the patient's primary oncology team)\n\nPediatric Oncology Clinicians\n\n1\\. Be a pediatric oncology physician, clinical fellow, or advanced practice provider (including nurse practitioners and physician assistants) that provides clinical care for AYA patients with cancer","ALL","15 Years","25 Years",{"count":59,"type":21},60,[24],"The overarching goal is to develop and demonstrate proof-of-concept of ReSPECT (Reproductive and Sexual Health Patient Education and Communication Tool), a multi-modal communication intervention to improve adolescent and young adult (AYA)- clinician sexual and reproductive health (SRH) communication in the outpatient oncology clinic setting.",[63,29],"Pediatric Cancer",[65,66,67,68,69],"adolescent young adult","sexual health communication","cancer","patient provider communication","sexual and reproductive health","2025-08-11",{"date":72,"type":39},"2025-08-14",{"date":74,"type":39},"2025-02-10",{"date":76,"type":21},"2029-06-29",{"name":78,"class":46},"Connecticut Children's Medical Center"]