[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"adolescent-hiv-infection\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:adolescent-hiv-infection":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,45],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":25,"briefSummary":27,"conditions":28,"keywords":30,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100583738","intensive-combination-approach-to-rollback-the-hiv-epidemic-in-nigerian-youth-icare-plus-effectivenessimplementation-hybrid-study-100583738",false,"NCT06880224","Intensive Combination Approach to Rollback the HIV Epidemic in Nigerian Youth (iCARE) Plus Effectiveness\u002FImplementation Hybrid Study","Intensive Combination Approach to Rollback the HIV Epidemic in Nigerian Youth (iCARE) Plus Effectiveness\u002FImplementation Hybrid Study: Aim 2","iCARE Plus","Inclusion Criteria:\n\nHIV Case Finding Intervention:\n\n* Aged 15 to 24\n* Male birth sex of any current gender identity\n* Understand basic English, Yoruba, Hausa, Igbo or Pidgin English For the PrEP component, must also be HIV-negative\n\nHIV Treatment Intervention:\n\n* Aged 15 to 24\n* HIV seropositive\n* Initiating ART for the first time at a Clinical Research Performance Site (CRPS) clinic or satellite clinic\n* Understand basic English, Yoruba, Hausa, Igbo or Pidgin English\n* Intention to remain a CRPS patient during follow-up\n\nExclusion Criteria:\n\n* Unable to provide consent\n* No parental permission if aged 15 and not emancipated",true,"ALL","15 Years","24 Years",{"count":22,"type":23},500,"ESTIMATED","INTERVENTIONAL",[26],"NA","Two combination interventions (HIV Case Finding Intervention and HIV Treatment Intervention), each with mHealth and Peer Navigation components, will be evaluated in two 48-week parallel hybrid effectiveness\u002Fimplementation trials among youth aged 15-24 in Nigeria.",[29],"Adolescent HIV Infection",[31],"Adolescents, HIV Testing, HIV Treatment","RECRUITING","2026-04-06",{"date":35,"type":36},"2026-04-08","ACTUAL",{"date":38,"type":36},"2025-02-01",{"date":40,"type":23},"2028-08-31",{"name":42,"class":43},"Northwestern University","OTHER",6,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":49,"acronym":50,"eligibilityCriteria":51,"healthyVolunteers":17,"sex":18,"minAge":52,"maxAge":4,"enrollmentInfo":53,"targetDuration":4,"studyType":24,"phases":55,"briefSummary":56,"conditions":57,"keywords":61,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":75},"100587106","scale-up-of-an-evidence-based-adolescent-transition-package-to-support-transitional-care-among-youth-living-with-hiv-100587106","NCT06924073","Scale-up of an Evidence-based Adolescent Transition Package to Support Transitional Care Among Youth Living With HIV","ATTACH-Scale","Inclusion Criteria:\n\nHealthcare providers\n\n* ≥18 years of age\n* Employed at one of the 32 facilities in the RCT\n* Provides HIV services to adolescents affiliated within their clinic Adolescents and youth living with HIV\n* Between 15-24 years of age (focus group discussions, surveys) or between 10-24 years of age (offered the intervention)\n* Receives HIV clinical care at one of the clinics included in the study\n* Attended clinic ≥1 time following intervention implementation\n\nExclusion Criteria:\n\nAny individual who meets the following criteria will be excluded from participation in this study:\n\n\\- Conditions that would place the individual at increased risk or preclude the individual's full compliance with or completion of the study","10 Years",{"count":54,"type":23},1920,[26],"Ending the HIV epidemic for youth living with HIV will require implementation and optimization of evidence-based interventions that address barriers to treatment. The proposed implementation study will test a youth-led data-driven implementation strategy to scale-up an evidence-based Adolescent Transition Package (ATP) aimed at improving transition processes and post-transition clinical outcomes for youth living with HIV in Kenya. Clinics will be randomized to receive standard of care implementation through trainer of trainers or the youth-led data-driven implementation strategy alongside trainer of trainers. We will study whether the enhanced implementation strategy improves the number of youth who receive the ATP, the number of providers that initially chose to use the ATP, and the consistency with which the ATP is used over time. We will also evaluate the cost of the ATP and whether the ATP improves health outcomes among youth living with HIV, including viral suppression and retention in care. Healthcare workers at study sites will complete surveys, focus group discussions, interviews, and participate in continuous quality improvement processes. Youth will participate in surveys and focus groups, and have their routine medical records abstracted.",[29,58,59,60],"Transition to Adult Care","Implementation Science","Implementation Strategies",[62,58,63,64,65],"Adolescent HIV","Scale-up","Implementation science","implementation strategy","2025-11-12",{"date":68,"type":36},"2025-11-14",{"date":70,"type":36},"2025-10-16",{"date":72,"type":23},"2029-01-30",{"name":74,"class":43},"University of Washington",25]