[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"adolescent-idiopathic-scoliosis-ais\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:adolescent-idiopathic-scoliosis-ais":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,16,0,[8,50,71,95,120,147,169,199,222,246,270,291,321,344,367,396],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":28,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100643611","understanding-the-causes-of-idiopathic-scoliosis-through-the-longitudinal-analysis-of-proteomic-markers-the-uncoil-study-100643611",false,"NCT07634627","UNderstanding the Causes Of Idiopathic Scoliosis Through the Longitudinal Analysis of Proteomic Markers: the UNCOIL Study","UNCOIL","Inclusion Criteria:\n\n* Patients 10-17 years old with idiopathic or neuromuscular scoliosis with a cobb angle of 10-50° that are currently being seen for their scoliosis at a Children's Hospital Colorado location\n\nExclusion Criteria:\n\n* Children diagnosed with certain genetic conditions that affect the bones or muscles (Turner syndrome, down syndrome, Marfan syndrome, osteogenesis imperfecta, muscular dystrophy, Ehlers-Danlos syndrome, VATER\u002FVACTERL syndrome, Rett syndrome, Prader Willi syndrome, or Angelman syndrome)\n* Patients with congenital scoliosis, early onset scoliosis (diagnosed before 9 years old), or those who have spine surgery scheduled prior to the first study visit\n* Patients whose spinal curve is \\>50 degrees\n* Those taking medications that may influence protein expression (baclofen, prednisone\u002Fcorticosteroids, antiepileptic medications, diazepam, tizanidine, and\u002For dantrolene)\n* Patients who are pregnant\n* Patients with neurocognitive disorders who are non-verbal and\u002For non-ambulatory\n* Patients who are not receiving care for scoliosis at a Children's Hospital Colorado location",true,"ALL","10 Years","17 Years",{"count":21,"type":22},500,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to find clinical, demographic, and protein biomarkers that scoliosis progression (scoliosis curve increases) and\u002For differ between participants with scoliosis versus those without scoliosis. The investigators aim to answer the following questions:\n\n1. Are age, sex, skeletal maturity, and family history associated with scoliosis curve progression?\n2. Do protein levels differ between progressive and non-progressive cases?\n3. Do protein levels change between baseline and follow-up visits in progressive and non-progressive scoliosis cases?\n4. Do proteins differ between participants with AIS vs those without AIS?\n5. Do proteins or change in proteins differ between participants with AIS vs those with scoliosis secondary to neuromuscular conditions.\n\nParticipants will:\n\n* Participate in two research visits 6-12 months apart at a Children's Hospital Colorado location.\n* Participate in a blood draw at each study visit to collect about 3 tablespoons of blood.\n* Fill out surveys yearly regarding new medical visits, pain, physical function, anxiety and depression, medical and family history, and current medications.",[26,27],"Adolescent Idiopathic Scoliosis (AIS)","Neuromuscular Scoliosis",[29,30,31,32,33,34,35,36],"Adolescent Idiopathic Scoliosis","Proteomics","AIS","Idiopathic Scoliosis","protein biomarkers","biomarkers","plasma proteomics","Neuromuscular scoliosis","RECRUITING","2026-06-18",{"date":40,"type":41},"2026-06-23","ACTUAL",{"date":43,"type":41},"2024-12-05",{"date":45,"type":22},"2031-12",{"name":47,"class":48},"University of Colorado, Denver","OTHER",1,{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":4,"eligibilityCriteria":56,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":57,"enrollmentInfo":58,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":59,"conditions":60,"keywords":4,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":4},"100637956","detection-of-scoliosis-100637956","NCT07581015","Detection of Scoliosis","Early Detection of Adolescent Idiopathic Scoliosis Using Machine Learning on Plantar Pressure Data","Inclusion Criteria:\n\n* Healthy Controls: Adolescents without any spinal condition or significant musculoskeletal issues, and with no prior history of scoliosis, to provide normal plantar pressure data for comparison.\n* Scoliosis Diagnosis: Adolescents diagnosed with adolescent idiopathic scoliosis (AIS) by a healthcare professional (through clinical evaluation and\u002For radiographic assessment) are eligible.\n* Age: Participants must be between the ages of 10 and 18 years at the time of recruitment.\n* Willingness to Participate: Participants and their parent(s)\u002Fguardian(s) must provide informed consent\u002Fassent prior to participation.\n* Ability to Complete Study Procedures: Participants must be able to complete the plantar pressure measurement test, which requires standing on a pressure mat for a few minutes.\n\nExclusion Criteria\n\n* Severe Pain or Discomfort: Participants unable to stand or walk comfortably due to pain or musculoskeletal issues.\n* Non-cooperation: Participants who are unable or unwilling to follow instructions or consent\u002Fassent procedures.\n* Uncontrolled Medical Conditions: Adolescents with uncontrolled conditions (e.g., cardiovascular or endocrine disorders) compromising participation.\n* Recent Foot Injuries or Conditions: Participants with foot injuries or conditions (e.g., wounds, infections) that may interfere with plantar pressure measurement.","18 Years",{"count":21,"type":22},"This study aims to evaluate whether plantar pressure data collected during standing and walking can be used with machine learning to support early detection of scoliosis in young people. Patients with scoliosis and healthy volunteers aged 10-18 will undergo a short assessment using a pressure mat.",[26],"NOT_YET_RECRUITING","2026-05-05",{"date":64,"type":41},"2026-05-12",{"date":66,"type":22},"2026-06",{"date":68,"type":22},"2028-07",{"name":70,"class":48},"University College, London",{"id":72,"slug":73,"hasResults":11,"nctId":74,"briefTitle":75,"officialTitle":76,"acronym":4,"eligibilityCriteria":77,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":57,"enrollmentInfo":78,"targetDuration":4,"studyType":80,"phases":81,"briefSummary":83,"conditions":84,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":49},"100638218","support-system-design-for-adolescent-scoliosis-orthosis-wear-100638218","NCT07574229","Support System Design for Adolescent Scoliosis Orthosis Wear","A Product System Intervention Study on Improving Wear Compliance and Psychological Motivation for Adolescent Idiopathic Scoliosis Patients Based on Sensory Monitoring and Interactive Feedback","Eligibility Criteria\n\nInclusion Criteria:\n\nClinical diagnosis of Adolescent Idiopathic Scoliosis (AIS).\n\nCurrent orthotic treatment with a prescription for a spinal brace (e.g., Boston, Milwaukee, or similar corrective braces).\n\nBetween 10 and 18 years of age at the time of enrollment.\n\nAbility to read, understand, and complete the Intrinsic Motivation Inventory (IMI) and other study-related questionnaires.\n\nAccess to a stable home environment with Wi-Fi or local network connectivity for the interactive desktop terminal.\n\nWillingness of the participant to provide assent and the legal guardian to provide written informed consent.\n\nExclusion Criteria:\n\nSecondary scoliosis caused by neuromuscular, congenital, or syndromic conditions (e.g., cerebral palsy or Marfan syndrome).\n\nScheduled spinal surgery within the planned study period.\n\nSevere skin allergies or chronic dermatological conditions at the brace contact sites that might be aggravated by sensor integration.\n\nPrevious participation in similar digital intervention studies for scoliosis management.\n\nDiagnosed cognitive impairments or severe psychological disorders that may interfere with accurate reporting or regular use of the product system.",{"count":79,"type":22},18,"INTERVENTIONAL",[82],"NA","This study focuses on improving the daily lives and treatment outcomes of teenagers diagnosed with Adolescent Idiopathic Scoliosis (AIS). For many young patients, wearing a corrective brace for 20+ hours a day is physically uncomfortable and psychologically challenging, leading to low compliance and emotional distress.The investigators have developed an integrated \"Product System\" designed to transform the bracing experience from a burdensome task into a guided, supportive journey. This system consists of three main components:Smart Sensing: Discrete, thin-film pressure sensors are integrated into the existing brace to monitor real-time wear time and fit quality without compromising comfort.Interactive Desktop Terminal: A dedicated device for the home that uses \"narrative-driven\" feedback (themed around a journey called \"The Spine's Path\"). Instead of cold medical data, it provides intuitive progress visualizations and rewards to keep participants engaged.Mobile Support App: A tool for both participants and parents to track long-term trends, access educational resources, and facilitate communication with healthcare providers.The Goal of the Study The primary objective is to evaluate how this digital intervention affects a participant's \"Intrinsic Motivation\"-the internal drive to adhere to treatment. By focusing on three psychological dimensions-Interest\u002FEnjoyment, Perceived Competence, and Pressure\u002FTension-the investigators aim to determine if interactive feedback can reduce the \"medical feel\" of the brace and help teenagers feel more in control of the recovery.What Participation Involves Participants will use the product system during the daily routine in home and school environments. The investigators will collect objective data (brace usage hours) and subjective data (through the Intrinsic Motivation Inventory\u002FIMI scale) to measure changes in behavior and mental well-being.Benefits for Families and ProvidersFor Participants: A more engaging, less stressful way to manage the condition and see real-time progress.For Families: Reduced friction regarding brace-wearing and better visibility into the participant's treatment status.For Healthcare Providers: Access to accurate, objective data on participant compliance, allowing for more personalized and effective clinical adjustments.",[26,85],"Adherence","2026-05-03",{"date":88,"type":41},"2026-05-07",{"date":90,"type":41},"2026-02-01",{"date":92,"type":22},"2026-10-01",{"name":94,"class":48},"Shanghai Jiao Tong University School of Medicine",{"id":96,"slug":97,"hasResults":11,"nctId":98,"briefTitle":99,"officialTitle":99,"acronym":100,"eligibilityCriteria":101,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":57,"enrollmentInfo":102,"targetDuration":4,"studyType":80,"phases":104,"briefSummary":106,"conditions":107,"keywords":108,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":111,"lastUpdatePostDateStruct":112,"startDateStruct":114,"completionDateStruct":116,"leadSponsor":118,"locationsCount":49},"100636141","phase-3-the-effect-of-erector-spinae-plane-block-espb-on-pediatric-pain-management-following-posterior-spinal-fusion-psf-surgery-100636141","NCT07561827","The Effect of Erector Spinae Plane Block (ESPB) on Pediatric Pain Management Following Posterior Spinal Fusion (PSF) Surgery","ESPB","Inclusion Criteria:\n\n* Diagnosis of Adolescent Idiopathic Scoliosis (AIS) or neuromuscular scoliosis\n* Undergoing Posterior Spinal Fusion (PSF) Surgery\n\nExclusion Criteria:\n\n* Patients with forms of scoliosis other than AIS or NM Scoliosis.\n* Patients undergoing a spinal deformity correction surgery other than Posterior Spinal Fusion Surgery\n* Allergy or other contraindication to erector spinae plane block (ESPB) with Ropivacaine patients who are taking pre-operative opioids",{"count":103,"type":22},42,[105],"PHASE3","This study is being done to better understand the efficacy of an erector spinae plane block (ESPB) in pain management for children with Adolescent Idiopathic Scoliosis or Neuromuscular Scoliosis undergoing Posterior Spinal Fusion surgery. The study team is trying to find out if receiving the ESPB leads to less pain and less need for pain medication after surgery.\n\nThe ESPB involves an injection of a local anesthetic, ropivacaine, into your child's back muscles to help block pain signals.",[26,27,29],[109,110],"posterior spinal fusion","pain management","2026-04-24",{"date":113,"type":41},"2026-05-01",{"date":115,"type":41},"2025-06-06",{"date":117,"type":22},"2027-01-26",{"name":119,"class":48},"University of California, San Francisco",{"id":121,"slug":122,"hasResults":11,"nctId":123,"briefTitle":124,"officialTitle":125,"acronym":4,"eligibilityCriteria":126,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":127,"targetDuration":4,"studyType":80,"phases":129,"briefSummary":130,"conditions":131,"keywords":132,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":138,"lastUpdatePostDateStruct":139,"startDateStruct":141,"completionDateStruct":143,"leadSponsor":145,"locationsCount":49},"100631454","basic-body-awareness-therapy-added-to-scoliosis-specific-exercise-in-adolescents-with-scoliosis-100631454","NCT07500883","Basic Body Awareness Therapy Added to Scoliosis-Specific Exercise in Adolescents With Scoliosis","Effects of Integrating Basic Body Awareness Therapy Into Scoliosis-Specific Exercises on Body Awareness, Quality of Life, and Scoliosis-Related Outcomes in Adolescents With Idiopathic Scoliosis: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Diagnosed of adolescent idiopathic scoliosis\n* Age between 10 and 17 years\n* Cobb angle ≥15°\n* No previous or concurrent scoliosis treatment\n* Risser sign between 0 and 4\n\nExclusion Criteria:\n\n* Evidence of congenital scoliosis or other spinal deformities (e.g., hyperkyphosis, pectus deformities)\n* Diagnosis of neuromuscular, rheumatologic, neurological, cardiovascular, pulmonary disorders\n* Regular participation in sports\n* History of spinal orthosis use or scoliosis surgery.",{"count":128,"type":22},40,[82],"The goal of this randomised clinical trial is to evaluate whether adding Basic Body Awareness Therapy (BBAT) to scoliosis-specific exercises can improve body awareness, quality of life and scoliosis-speficic outcomes in adolescents aged 10-17 years with adolescent idiopathic scoliosis (AIS). The main questions it aims to answer are:\n\nDoes the addition of BBAT to scoliosis-specific exercises lead to greater improvements in body awareness compared to scoliosis-specific exercises alone? Does adding BBAT improve trunk proprioception, scoliosis-related parameters, and health-related quality of life in adolescents with AIS?\n\nH1: Adolescents with idiopathic scoliosis who receive Basic Body Awareness Therapy in addition to scoliosis-specific exercises will demonstrate greater improvements in body awareness compared to those receiving scoliosis-specific exercises alone.\n\nH2: Adolescents receiving Basic Body Awareness Therapy in addition to scoliosis-specific exercises will demonstrate greater improvements in scoliosis-related clinical parameters compared to those receiving scoliosis-specific exercises alone.\n\nH3: Adolescents receiving Basic Body Awareness Therapy in addition to scoliosis-specific exercises will demonstrate greater improvements in both general and scoliosis-specific quality of life compared to those receiving scoliosis-specific exercises alone.",[26],[133,134,135,136,137],"scoliosis","awareness","quality of life","rehabilitation","adolescent","2026-03-24",{"date":140,"type":41},"2026-03-30",{"date":142,"type":41},"2025-11-12",{"date":144,"type":22},"2026-04",{"name":146,"class":48},"Gözde Yagci (Gür)",{"id":148,"slug":149,"hasResults":11,"nctId":150,"briefTitle":151,"officialTitle":152,"acronym":4,"eligibilityCriteria":153,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":57,"enrollmentInfo":154,"targetDuration":4,"studyType":80,"phases":156,"briefSummary":157,"conditions":158,"keywords":159,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":161,"lastUpdatePostDateStruct":162,"startDateStruct":164,"completionDateStruct":166,"leadSponsor":168,"locationsCount":49},"100544208","open-label-placebo-colp-for-pain-in-adolescent-idiopathic-scoliosis-ais-surgerysurgical-treatment-of-idiopathic-scoliosis-100544208","NCT06365892","Open-label Placebo (COLP) for Pain in Adolescent Idiopathic Scoliosis (AIS) Surgery+Surgical Treatment of Idiopathic Scoliosis","Effectiveness of Conditioning + Open-label Placebo for the Management of Pain in Children Who Undergo Surgical Treatment of Idiopathic Scoliosis","Inclusion Criteria:\n\nTo be eligible for enrollment, patients must meet all of the following inclusion criteria:\n\n1. Diagnosis of idiopathic spine deformity.\n2. Age \\>10 and \\\u003C18 years.\n3. Primary procedure.\n4. Guardian provides signed and dated informed consent and understand the nature of the study sufficiently to allow completion of all study assessments.\n5. Patient provides assent.\n6. Fusion and fusionless instrumented spine surgery.\n\nExclusion Criteria:\n\nIf any of the following exclusion criteria are met, the patient is not eligible for the study:\n\n1. Non-idiopathic scoliosis, such as neuromuscular or syndrome.\n2. Revision procedure.\n3. Self-reported pregnancy or planned pregnancy within the next two months.\n4. Have a history of drug, excluding nicotine or caffeine, or alcohol abuse within 2 years of entry into the study\n5. Already taking opioids.\n6. Abnormal physical examination.\n7. Inability to speak or read English\n8. Patient declines participation.",{"count":155,"type":22},64,[82],"This study aims to investigate the effects of conditioning with open-label placebos on standard postoperative treatment for patients undergoing surgery for idiopathic scoliosis in a randomized controlled, 6-week trial with 64 AIS patients randomly assigned to one of two arms: Open-label Placebo (COLP) + treatment as usual TAU \u002F TAU control. The study involves collecting data from your child's medical record. At each regular clinic visit, the patient clinical data will be collected by the research coordinator. Surveys will be collected including:• PROMIS for the age group 10 to 18 years.",[26],[160],"Conditioning with Open-Label Placebo (COLP)","2026-03-10",{"date":163,"type":41},"2026-03-13",{"date":165,"type":41},"2024-07-01",{"date":167,"type":22},"2026-12",{"name":119,"class":48},{"id":170,"slug":171,"hasResults":11,"nctId":172,"briefTitle":173,"officialTitle":174,"acronym":175,"eligibilityCriteria":176,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":177,"targetDuration":4,"studyType":80,"phases":179,"briefSummary":180,"conditions":181,"keywords":182,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":190,"lastUpdatePostDateStruct":191,"startDateStruct":193,"completionDateStruct":195,"leadSponsor":197,"locationsCount":49},"100627751","small-study-comparing-two-pain-medicines-in-teenagers-for-pain-control-after-scoliosis-corrective-surgery-100627751","NCT07452705","Small Study Comparing Two Pain Medicines in Teenagers for Pain Control After Scoliosis Corrective Surgery.","Patient-Controlled Analgesia (PCA) With Ketamine-Morphine (PCA KetaMorph) vs PCA Morphine for Postoperative Analgesia in Idiopathic Scoliosis Surgery - A Randomized Controlled Trial","KetaMorph","Inclusion criteria:\n\n1. Aged \\> 10 years old\n2. Idiopathic scoliosis scheduled for single-stage posterior spinal fusion (PSF).\n3. American Society of Anaesthesiologists (ASA) physical status I-II.\n\nExclusion criteria:\n\n1. Known hypersensitivity to morphine, ketamine or formulation excipients.\n2. Hepatic dysfunction (ALT or AST \\> 2 × upper limit of normal).\n3. Renal impairment (eGFR ≤ 60 mL min-¹ 1·73 m-²).\n4. Uncontrolled asthma or severe restrictive lung disease.\n5. Cardiac disease or clinically significant arrhythmia.\n6. Epilepsy.\n7. Intellectual disability precluding PCA use.\n8. Chronic opioid therapy or pre-operative pain \\> 3 months.\n9. Concomitant monoamine-oxidase inhibitor or tricyclic antidepressant therapy.\n10. History of severe postoperative delirium.",{"count":178,"type":22},114,[82],"The goal of this clinical trial is to evaluate whether adding low-dose ketamine to PCA morphine reduces opioid requirements after posterior spinal fusion surgery in adolescent idiopathic scoliosis patients. Selected patients aged 10-18 years undergoing elective AIS surgery at University Malaya Medical Centre will be randomised to ketamine-morphine or morphine-only PCA. The primary outcome is cumulative morphine consumption at 48 hours, with secondary outcomes including pain scores, opioid-related adverse effects, time to ambulation, and patient satisfaction. This study aligns with national priorities for safe opioid stewardship and enhanced peri-operative care in Malaysia.",[26],[183,184,185,186,187,188,189],"Adolescent","Analgesia","Ketamine","Morphine","Pain management","Pain-controlled","Spinal fusion","2026-03-01",{"date":192,"type":41},"2026-03-05",{"date":194,"type":22},"2026-02-02",{"date":196,"type":22},"2028-01-30",{"name":198,"class":48},"University of Malaya",{"id":200,"slug":201,"hasResults":11,"nctId":202,"briefTitle":203,"officialTitle":204,"acronym":4,"eligibilityCriteria":205,"healthyVolunteers":11,"sex":17,"minAge":206,"maxAge":57,"enrollmentInfo":207,"targetDuration":4,"studyType":80,"phases":208,"briefSummary":209,"conditions":210,"keywords":212,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":214,"lastUpdatePostDateStruct":215,"startDateStruct":217,"completionDateStruct":218,"leadSponsor":220,"locationsCount":49},"100627442","effects-of-lumbar-traction-combined-with-3d-exercise-therapy-on-adolescent-idiopathic-scoliosis-100627442","NCT07448688","Effects of Lumbar Traction Combined With 3D Exercise Therapy on Adolescent Idiopathic Scoliosis","Impact of Combined Lumbar Spinal Traction and Three-Dimensional Exercise Therapy on Spinal Curve Parameters and Clinical Outcomes in Patients With Adolescent Idiopathic Scoliosis","Inclusion Criteria:\n\n* Diagnosed with AIS\n* Having a Cobb angle between 10° and 25°\n* With a Risser stage \\\u003C 4\n* Willing to participate in the study\n* Patients whose informed consent forms are signed by both the parents and the child\n\nExclusion Criteria:\n\n* History of previous exercise therapy, manual therapy, or other physical therapy interventions\n* Current use of brace treatment\n* Presence of contraindications for exercise or lumbar spinal traction (e.g., diagnoses such as rickets, osteomalacia)\n* Non-idiopathic scoliosis caused by neuromuscular disorders, vertebral malformations, trauma, tumors, or other diseases\n* History of previous surgery involving the spine or lower extremities\n* Comorbid psychiatric problems, or neuromuscular, cardiovascular, pulmonary, or rheumatic diseases","12 Years",{"count":128,"type":22},[82],"Adolescent Idiopathic Scoliosis (AIS) is a three-dimensional spinal deformity that appears during adolescence without an identifiable underlying cause.\n\nA variety of low-risk physical therapy modalities, such as TENS, acupuncture, kinesio taping, spinal manipulation, and mobilization, have been explored in the management of scoliosis. Among these approaches, lumbar mechanical spinal traction is a commonly used non-invasive and painless intervention in physical medicine and rehabilitation settings. However, existing research on traction in AIS remains limited and generally of low methodological quality. Preliminary and observational studies have reported mixed outcomes, and the clinical effectiveness of traction appears to depend on factors such as curve characteristics, treatment dose, and integration with active rehabilitation. To date, high-quality randomized controlled evidence evaluating lumbar mechanical spinal traction as an adjunct to scoliosis-specific exercises in AIS is lacking.\n\nThis study aims to investigate the combined effects of lumbar mechanical spinal traction and scoliosis-specific exercises in adolescents diagnosed with AIS. A prospective randomized controlled design will be used to assess changes in Cobb angle, posture, pain, and functional status. The findings may help clarify whether adding mechanical traction provides additional benefit beyond exercise alone in the conservative treatment of AIS.",[26,211],"Exercise (EX)",[213],"mechanical traction","2026-02-28",{"date":216,"type":41},"2026-03-04",{"date":192,"type":22},{"date":219,"type":22},"2026-12-05",{"name":221,"class":48},"Şahide Eda ARTUÇ",{"id":223,"slug":224,"hasResults":11,"nctId":225,"briefTitle":226,"officialTitle":227,"acronym":228,"eligibilityCriteria":229,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":230,"enrollmentInfo":231,"targetDuration":4,"studyType":80,"phases":233,"briefSummary":234,"conditions":235,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":237,"lastUpdatePostDateStruct":238,"startDateStruct":240,"completionDateStruct":242,"leadSponsor":244,"locationsCount":49},"100498726","psychological-assessment-of-scoliosis-patients-undergoing-surgical-management-100498726","NCT05774002","Psychological Assessment of Scoliosis Patients Undergoing Surgical Management","Psychological Assessment of Scoliosis Patients Undergoing Surgical Management (PASS)","PASS","Inclusion Criteria:\n\n* Diagnosis of scoliosis prior to age 20\n* Healthy, non-obese aged 10-19 years, with a diagnosis of idiopathic scoliosis, undergoing elective posterior spinal fusion\n\nExclusion Criteria:\n\n* Diagnosis of scoliosis after age 20\n* Permanent cognitive impairment\n* Pregnant or breastfeeding women\n* Use of opioids in the last 6 months\n* Liver or renal diseases and developmental delays","19 Years",{"count":232,"type":22},120,[82],"Working in partnership with Montefiore-Einstein's Department of Translational Psychiatry, the investigators have designed a prospective randomized clinical trial (2:1) study for 45 Adolescent Idiopathic Scoliosis (AIS) patients, 10-19 years of age. This protocol includes a baseline assessment of mental health, pain, and function in AIS patients utilizing validated patient reported outcome (PRO) measures. The investigators will implement and test a structured perioperative psychological intervention program, based on the Aim to Decrease Anxiety and Pain Treatment (ADAPT), which was developed based on evidence-based cognitive behavioral therapy (CBT) protocols for the management of pediatric pain and childhood anxiety disorders",[26,236],"Mental Health","2026-02-26",{"date":239,"type":41},"2026-03-02",{"date":241,"type":41},"2023-10-06",{"date":243,"type":22},"2028-10",{"name":245,"class":48},"Montefiore Medical Center",{"id":247,"slug":248,"hasResults":11,"nctId":249,"briefTitle":250,"officialTitle":251,"acronym":4,"eligibilityCriteria":252,"healthyVolunteers":16,"sex":17,"minAge":253,"maxAge":57,"enrollmentInfo":254,"targetDuration":4,"studyType":80,"phases":256,"briefSummary":257,"conditions":258,"keywords":259,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":261,"lastUpdatePostDateStruct":262,"startDateStruct":264,"completionDateStruct":266,"leadSponsor":268,"locationsCount":49},"100540265","personalized-prevention-and-treatment-strategies-for-adolescent-idiopathic-scoliosis-via-a-comprehensive-health-management-platform-100540265","NCT06314594","Personalized Prevention and Treatment Strategies for Adolescent Idiopathic Scoliosis Via a Comprehensive Health Management Platform","The Individualized Stepwise Treatment Mode of Adolescent Idiopathic Scoliosis","Inclusion Criteria:\n\n1. The diagnosis of moderate and mild AIS, with a Cobb angle measuring less than 45°;\n2. The age range of 12 to 16 years old;\n3. Participants are required to have no history of mental illness, possess normal communication skills, and be proficient in reading and writing;\n4. Signed informed consent by the patient or their family.\n\nExclusion Criteria:\n\nPatients who fulfill any of the following conditions will be excluded a clear history of inducement, such as diseases caused by trauma, surgery, cognitive impairment, severe dysfunction of heart, liver, kidney and other organs, and malignant tumors, immune diseases and other malignant diseases.","3 Years",{"count":255,"type":22},76,[82],"Spinal cord injury (SCI), leads to functional deficits and complications like neurogenic bladder and deep vein thrombosis, imposing a global annual financial burden. This trial aims to compares Jiaji electroacupuncture (JEA) and scalp electroacupuncture (SEA) in SCI rehabilitation. This randomized controlled trial (RCT) compared JEA and SEA in SCI rehabilitation.",[26],[260],"spinal cord injury; electroacupuncture; Jiaji acupoint; scalp acupuncture; clinical efficacy","2026-02-19",{"date":263,"type":41},"2026-02-23",{"date":265,"type":41},"2025-08-01",{"date":267,"type":22},"2026-12-01",{"name":269,"class":48},"Hangzhou Medical College",{"id":271,"slug":272,"hasResults":11,"nctId":273,"briefTitle":274,"officialTitle":275,"acronym":4,"eligibilityCriteria":276,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":57,"enrollmentInfo":277,"targetDuration":4,"studyType":80,"phases":279,"briefSummary":280,"conditions":281,"keywords":4,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":283,"lastUpdatePostDateStruct":284,"startDateStruct":286,"completionDateStruct":288,"leadSponsor":289,"locationsCount":4},"100569800","evaluation-of-a-chatbot-delivered-structured-psychological-intervention-for-teenagers-with-adolescent-idiopathic-scoliosis-100569800","NCT06698952","Evaluation of a Chatbot-Delivered Structured Psychological Intervention for Teenagers With Adolescent Idiopathic Scoliosis","Evaluation of a Chatbot-Delivered Structured Psychological Intervention (SPI-Bot) for Teenagers With Adolescent Idiopathic Scoliosis: A Pilot Randomized Controlled Trial","Inclusion Criteria:\n\n* Have a Cobb angle (a standard method for measuring spinal curvature) greater than 10 degrees;\n* Exhibit mild to moderate levels of depression, anxiety, or stress (scoring between 7-13 on the depression subscale, 6-12 on the anxiety subscale, or 12-16 on the stress subscale of the Depression Anxiety Stress Scales for Youth);\n* Be aged between 10 and 18;\n* Be proficient in Cantonese and traditional Chinese character reading;\n* Own a smartphone and being adept at using it.\n\nExclusion Criteria:\n\n* Have a diagnosis of psychiatric disorders or serious physical diseases;\n* Are currently undergoing other psychological interventions;\n* Are on a surgery waiting list or in the perioperative period (from seven days before to seven days after surgery);\n* Are unable to provide consent for study participation;\n* Exhibit self-harm or suicidal tendencies (scoring \\> 0 on the ninth item of the Patient Health Questionnaire-9: \"Thoughts that you would be better off dead, or of hurting yourself in some way\").",{"count":278,"type":22},52,[82],"Adolescent idiopathic scoliosis is the most common spinal deformity in children and can significantly impact the psychological health of affected teenagers. Despite this, there are few effective psychological treatments available for this population. Cognitive and behavioral strategies show promise in addressing the challenges associated with the condition and its treatment. Chatbots could serve as an accessible and effective tool to support the psychological health of these teenagers.\n\nUsing the Centre for eHealth Research and Disease Management Roadmap as a guide, a chatbot-based structured psychological intervention has been developed. This intervention incorporates cognitive and behavioral strategies and aims to improve the psychological health of teenagers with adolescent idiopathic scoliosis. The current phase involves implementing the intervention and conducting a pilot test to assess its feasibility, acceptability, and preliminary effectiveness.\n\nThe study will employ a pilot randomized controlled trial design, nested with qualitative interviews. Participants will be recruited from community health organizations in Hong Kong and will be randomly assigned to either a control group or an intervention group using block randomization. The intervention group will engage with the chatbot-based structured psychological intervention for eight consecutive weeks. The control group will interact with a different generative chatbot, participating in casual conversations at a similar frequency. Quantitative assessments will be conducted at three points: baseline, immediately after the intervention, and one month after the intervention. Additionally, qualitative interviews will be held with selected participants from the intervention group at post-intervention to explore their experiences and perceptions of the intervention process.",[26,282],"Psychological Health","2025-06-05",{"date":285,"type":41},"2025-06-10",{"date":287,"type":22},"2025-08-15",{"date":90,"type":22},{"name":290,"class":48},"The Hong Kong Polytechnic University",{"id":292,"slug":293,"hasResults":11,"nctId":294,"briefTitle":295,"officialTitle":296,"acronym":297,"eligibilityCriteria":298,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":299,"enrollmentInfo":300,"targetDuration":4,"studyType":80,"phases":302,"briefSummary":303,"conditions":304,"keywords":305,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":311,"lastUpdatePostDateStruct":312,"startDateStruct":314,"completionDateStruct":315,"leadSponsor":317,"locationsCount":320},"100587891","phase-3-pooled-human-plasma-vs-crystalloid-in-the-management-of-children-undergoing-instrumented-spinal-fusion-for-scoliosis-100587891","NCT06934278","Pooled Human Plasma vs Crystalloid in The Management of Children Undergoing Instrumented Spinal Fusion for Scoliosis","Pooled Human Plasma vs Crystalloid in The Management of Children Undergoing Instrumented Spinal Fusion for Scoliosis: A Double-Blind, Randomized Clinical Trial","OCTAGON","Inclusion Criteria:\n\n* Written informed consent.\n* Aged between 10 and 21 years of age\n* Scoliosis requiring posterior scoliosis surgery using all pedicle screw technique for AIS (\\>45-degree major curve) or NMS (\\>50-degree major curve)\n* Normal whole spine MRI except for the spinal deformity (only for patients with adolescent idiopathic scoliosis as patients with neuromuscular scoliosis do not typically undergo MR images as they would need general anaesthesia)\n\nExclusion Criteria:\n\n* Immunoglobulin A-deficiency\n* Need for anteroposterior surgery\n* Need for three column vertebral resection\n* Smoking\n* Diabetes mellitus\n* Abnormalities in blood coagulation (thromboplastin time below above or below of normal values, 70-130%)\n* Blood trombosytes less than 150 x E9\u002Fl\n* Body mass index over 40\n* Allergy or hypersensitivity to study medications or their ingredients\n* Pregnancy or breast-feeding, aim of becoming pregnant during the study.\n* Participation in another study and receipt of any other investigational agent during 2 year period of current investigation\n* Inability to provide written informed consent\n* Any significant disease or disorder which, in the opinion of the investigator, may either put the subject at risk by participation in the study, or may influence the result of the study.\n* A history of drug or alcohol use that, in the opinion of the investigator, would interfere with adherence to study requirements.\n* Known history of, or documented positive hepatitis B or C or HIV infection Prior or concurrent malignancy\n* Aspartate transaminase (AST) or alanine transaminase (ALT) ≥ 3 x upper-limit of normal\n* Creatinine clearance (CrCl) \\\u003C 60 ml\u002Fmin measured by 24-hour urine collection or estimated from the Cockcroft and Gault formula\n* Clinically significant ECG findings as judged by the investigator\n* Amiodarone medication\n* Hyperkalemia\n* Renal insufficiency\n* AV-block\n* Metabolic or respiratory alkalosis\n* Hypochlorhydria\n* Hypersensitivity for active component or additives.","21 Years",{"count":301,"type":22},194,[105],"OCTAGON trial is a randomized, double-blinded, parallel-group non-inferiority multicenter (Helsinki and Turku University Hospitals, Finland) clinical trial according to CONSORT criteria.\n\n194 adolescents with idiopathic (major curve \\> 45 degrees) or neuromuscular scoliosis (major curve \\> 50 degrees) are enrolled for the OCTAGON trial comparing pooled human plasma (Octaplas, 10mL\u002Fkg, active management) vs. Plasmalyte (10 mL\u002Fkg, placebo) before incision as part of the normal intraoperative fluid therapy. Data is collected at baseline and at each follow-up until a minimum of 2-year follow-up.\n\nOutcomes Outcomes for the OCTAGON trial include 1) intraoperative blood loss (in mL, primary outcome) and the need for allogenic red blood cell infusion (percentage of patients). Secondary outcomes include health-related quality of life (Scoliosis Research Society 24 outcome questionnaire), postoperative pain (48-hour opioid consumption), operative time (hours), drain output (mL), hidden blood loss (mL), hospital stay, and complications (skin reactions, TRALI, deep surgical site infection, neurologic deficit).\n\nResearch questions and hypothesis Does prophylactic use of pooled human plasma decrease intraoperative blood loss in adolescents undergoing instrumented spinal fusion for scoliosis? We hypothesize that pooled human plasma will reduce intraoperative and total blood loss by 25% resulting in lower need for blood transfusion and fewer surgical site infections.\n\nObjectives To compare the effect of pooled human plasma vs. crystalloid fluids on intraoperative bleeding and total blood loss (drain output and hidden blood loss) in children undergoing posterior spinal fusion for AIS and NMS. Adverse events will be recorded and reported as minor (skin reaction) or major (severe allergic reaction, transfusion related acute lung injury, TRALI, deep surgical site infection, neurologic injury).\n\nEthical aspects The PHP trial has been evaluated via European regulatory authority (EU CT: 2024-514857-31-00) and by Fimea (FIMEA\u002F2024\u002F006588). Informed consent is obtained from the parent(s). Results will be disseminated in high-quality peer-reviewed publications.\n\nThe individual patient safety and high-quality management of fractures and scoliosis is a priority in this trial. The randomization can be opened at any stage of the treatment process. Based on the clinical decision the randomized treatment can be terminated and treatment provided accord-ing to clinical decision making even if results will be evaluated using the intention to treat princi-ple. Pain management will be prioritized in every clinical scenario and parental presence is always possible.",[26,27],[306,307,308,309,310],"adolescent idiopathic scoliosis","neuromuscular scoliosis","pooled human plasma","randomized clinical trial","double-blind placebo controlled","2025-05-02",{"date":313,"type":41},"2025-05-07",{"date":311,"type":41},{"date":316,"type":22},"2030-12-31",{"name":318,"class":319},"Turku University Hospital","OTHER_GOV",2,{"id":322,"slug":323,"hasResults":11,"nctId":324,"briefTitle":325,"officialTitle":326,"acronym":4,"eligibilityCriteria":327,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":328,"targetDuration":4,"studyType":80,"phases":330,"briefSummary":331,"conditions":332,"keywords":333,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":336,"lastUpdatePostDateStruct":337,"startDateStruct":339,"completionDateStruct":341,"leadSponsor":343,"locationsCount":320},"100581801","effects-of-body-awareness-therapy-on-posture-trunk-movement-scoliosis--body-awareness-in-adolescents-with-scoliosis-100581801","NCT06855030","Effects of Body Awareness Therapy on Posture, Trunk Movement, Scoliosis & Body Awareness in Adolescents With Scoliosis","The Effect of Basic Body Awareness Therapy on Posture, Trunk Proprioception, Clinical Parameters of Scoliosis and Body Awareness in Adolescents With Idiopathic Scoliosis","Inclusion Criteria:\n\n* Being diagnosed with adolescent idiopathic scoliosis\n* Being between the ages of 10 and 17\n* Having scoliosis of 15° or greater\n* Not having received previous treatment for scoliosis and not receiving any other treatment during this study\n* Risser stage 0-4\n* Willing to participate in the study\n\nExclusion Criteria:\n\n* Having any spinal\u002Fbone deformity in addition to scoliosis (such as hyperkyphosis, pectus, etc.)\n* Wearing a brace\n* Having congenital scoliosis\n* Having any rheumatological, neuromuscular, neurological, cardiovascular, or pulmonary pathology\n* Having a regular history or habit of physical activity\n* Having undergone scoliosis surgery",{"count":329,"type":22},30,[82],"Adolescent idiopathic scoliosis (AIS) is a complex deformity of the spine, and its cause remains unknown. AIS can have negative physical, psychological, and social effects on an individual's health. There are two main treatment options for AIS: surgical and conservative approaches, including observation, exercise, and bracing. Scoliosis-specific exercises (SSE) refer to globally recognized, evidence-based exercise approaches.\n\nIn this study, the Scientific Exercise Approach to Scoliosis (SEAS), one of the SSE methods, will be used. SEAS consists of individualized active self-correction exercises combined with functional movements. Additionally, the Basic Body Awareness Therapy (BBAT) method will also be applied. BBAT is a body-focused, comprehensive approach that incorporates slow, rhythmic movements and breath control.\n\nBoth groups will attend supervised sessions in the clinic once a week, and home exercises will be assigned for the remaining days. Participants in the SEAS group will receive only SEAS treatment, while those in the BBAT group will receive both SEAS and additional BBAT exercises.\n\nThe goal of this clinical study is to investigate the effects of BBAT in addition to a rehabilitation program including SSE, on posture, spatial orientation, trunk proprioception, scoliosis-specific parameters, quality of life, and body in adolescents with IS aged between 10 and 17 years.\n\nThe research hypotheses for this study are as follows:\n\nH1: Basic Body Awareness Therapy has an effect on posture in adolescents with idiopathic scoliosis.\n\nH2: Basic Body Awareness Therapy has an effect on spatial orientation in adolescents with idiopathic scoliosis.\n\nH3: Basic Body Awareness Therapy has an effect on trunk proprioception in adolescents with idiopathic scoliosis.\n\nH4: Basic Body Awareness Therapy has an effect on scoliosis-specific clinical parameters in adolescents with idiopathic scoliosis.\n\nH5: Basic Body Awareness Therapy has an effect on both general and scoliosis-specific quality of life in adolescents with idiopathic scoliosis.\n\nH6: Basic Body Awareness Therapy has an effect on body awareness in adolescents with idiopathic scoliosis.",[26],[133,134,334,335],"proprioception","Physiotherapy","2025-04-14",{"date":338,"type":41},"2025-04-15",{"date":340,"type":22},"2025-04",{"date":342,"type":22},"2025-07",{"name":146,"class":48},{"id":345,"slug":346,"hasResults":11,"nctId":347,"briefTitle":348,"officialTitle":349,"acronym":4,"eligibilityCriteria":350,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":57,"enrollmentInfo":351,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":352,"conditions":353,"keywords":354,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":360,"lastUpdatePostDateStruct":361,"startDateStruct":363,"completionDateStruct":364,"leadSponsor":366,"locationsCount":49},"100585576","investigation-of-shoulder-position-upper-extremity-proprioception-and-function-in-adolescents-with-idiopathic-scoliosis-using-braces-100585576","NCT06904157","Investigation of Shoulder Position, Upper Extremity Proprioception, and Function in Adolescents With Idiopathic Scoliosis Using Braces","Investigation of Shoulder Head Position, Upper Extremity Proprioception, and Upper Extremity Function in Adolescents With Idiopathic Scoliosis Using Braces","Inclusion Criteria:\n\n\\- Inclusion criteria for the patient group;\n\n* To have a diagnosis of adolescent idiopathic scoliosis (AIS),\n* Be using Cheneau Type corset for at least one month,\n* Having a primary thoracic or thoracolumbar curve,\n* Cobb angle of 20 degrees or more,\n* The dominant hand is the right hand,\n* Volunteering to participate in the study,\n* Parental consent was required. Inclusion criteria for the control group;\n* Individuals between the ages of 10-18\n* Dominant Hand is the Right Hand\n* Volunteering to Participate in the Study\n\nExclusion Criteria:\n\nExclusion Criteria for Patient Group;\n\n* Having a diagnosis of Congenital Scoliosis,\n* Becoming a Professional Athlete,\n* Neuromuscular, Rheumatologic, Renal Except Scoliosis, Any History of Vestibular, Pulmonary or Cardiovascular Disease Finding\n* History of Surgical Intervention on the Spine. Exclusion Criteria for Control Group;\n* Neuromuscular, Rheumatologic, Renal, Vestibular, Pulmonary Or History of any Cardiovascular Disease\n* History of Spine Surgery,\n* Being a Professional Athlete.",{"count":329,"type":22},"This study aims to investigate the effects of brace use on shoulder position, upper extremity proprioception, and upper extremity function in adolescents with idiopathic scoliosis. Participants will be assessed under both in-brace and out-brace conditions. The control group's upper extremity proprioception and upper extremity function will be assessed under out-brace condition. Shoulder position will be evaluated using a photographic method, while upper extremity proprioception (angular deviation) will be measured with the Laser Pointer-Assisted Angle Reproduction Test. Upper extremity function will be assessed through muscle strength tests, the Closed Kinetic Chain Upper Extremity Stability Test, the Medicine Ball Throw Test, the Finger-to-Nose Test, the Nellson Hand Reaction Test, and the Minnesota Manual Dexterity Test. Adolescents diagnosed with idiopathic scoliosis who have been prescribed brace treatment and have no history of spinal surgery or neurological\u002Fmusculoskeletal conditions affecting upper extremity function will be included. Individuals with congenital or neuromuscular scoliosis, previous spinal surgery, neurological disorders affecting proprioception, or those unable to comply with study assessments will be excluded. This study aims to provide insights into the impact of bracing on proprioception and upper extremity function, contributing to the development of rehabilitation strategies for scoliosis management.",[26],[355,356,357,358,359],"Scoliosis","Brace","Upper Extremity","Proprioception","Function","2025-03-24",{"date":362,"type":41},"2025-04-01",{"date":362,"type":22},{"date":365,"type":22},"2025-06-30",{"name":146,"class":48},{"id":368,"slug":369,"hasResults":11,"nctId":370,"briefTitle":371,"officialTitle":372,"acronym":4,"eligibilityCriteria":373,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":230,"enrollmentInfo":374,"targetDuration":4,"studyType":80,"phases":376,"briefSummary":377,"conditions":378,"keywords":380,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":387,"lastUpdatePostDateStruct":388,"startDateStruct":390,"completionDateStruct":392,"leadSponsor":394,"locationsCount":49},"100573954","effects-of-expiratory-muscle-strength-training-in-adolescent-idiopathic-scoliosis-100573954","NCT06752993","Effects of Expiratory Muscle Strength Training in Adolescent Idiopathic Scoliosis","Effects of Expiratory Muscle Strength Training on Cobb Angle, Respiratory Muscle Strength, Core Stabilization, Functional Exercise Capacity and Quality of Life in Adolescent Idiopathic Scoliosis","Inclusion Criteria:\n\n* Individuals diagnosed with idiopathic scoliosis,\n* aged between 10 and 19 years,\n* with a Cobb angle ranging from 10 to 45 degrees.\n\nExclusion Criteria:\n\n* Individuals who have undergone spinal surgery,\n* who have received conservative or surgical treatment for scoliosis,\n* individuals with neurological, neuromuscular, systemic, rheumatological, or musculoskeletal disorders, or conditions affecting balance and walking,\n* individuals with a history of cardiac or pulmonary diseases that could affect respiratory function and exercise capacity.",{"count":375,"type":22},24,[82],"Adolescent idiopathic scoliosis result in deterioration of core muscles and respiratory system. Core muscles provide trunk stabilization as well as responsible for respiratory system. Especially tr. abdominis, rectus abdominis, external oblic and internal oblic muscle, which are core muscles, highly active during forced expiration while diaphragm muscle also active during inspiration. Thus, expiratory muscle strength training has effect not only respiratory muscle strength but also trunk stabilization. While, effects of expiratory muscle strength training in adolesecent idiopathic scoliosis is a topic that needs to be investigated, this topic has not been investigated until today. Hence, this current study aimed to investigate the effects of expiratory muscle strength training on cobb angle, respiratory muscle strength, core stabilization, functional exercise capacity and quality of life.",[26,379],"Scoliosis; Adolescence",[381,382,383,384,385,386],"Adolescent idiopathic scoliosis","Expiratory muscle strength training","Cobb angle","Core stability","Functional exercise capacity","Respiratory muscle stregth","2024-12-20",{"date":389,"type":41},"2024-12-31",{"date":391,"type":22},"2025-01-04",{"date":393,"type":22},"2025-07-02",{"name":395,"class":48},"Gazi University",{"id":397,"slug":398,"hasResults":11,"nctId":399,"briefTitle":400,"officialTitle":400,"acronym":4,"eligibilityCriteria":401,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":57,"enrollmentInfo":402,"targetDuration":404,"studyType":23,"phases":4,"briefSummary":405,"conditions":406,"keywords":408,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":411,"lastUpdatePostDateStruct":412,"startDateStruct":414,"completionDateStruct":416,"leadSponsor":417,"locationsCount":49},"100564497","correlation-between-the-cobbs-angle-and-the-forward-head-posture-in-patients-with-adolescent-idiopathic-scoliosis-100564497","NCT06629948","Correlation Between the Cobb's Angle and the Forward Head Posture in Patients With Adolescent Idiopathic Scoliosis","Inclusion Criteria:\n\n* 1- Patients with AIS. 2- Patient with forward head posture CVA less than 48 degress. (Fard et al .,2021) 3- Patients aged between 10 and 18 years, (Upasani et al., 2007). 4- Patients who underwent Posterioanterior (PA) and lateral X-ray radiography, and Cobb angle \\>10°.(Nasser et al.,2023) 5- Patients with Lenke types (1 to 6). 6- No previous spine surgery ((Wang, et al., 2017).\n\nExclusion Criteria:\n\n* 1- Patients with congenital scoliosis (including hemivertebrae, butterfly vertebrae, and failure of segmentation), (Shu-Man Han et al., 2022 and Nasser et al., 2023).\n\n  2- Other developmental thoracic deformity (funnel chest etc.). 3- Scoliosis with definitive reasons (secondary to neurofibromatosis, Marfan syndrome, and syringomyelia).\n\n  4- Patients with neurologic deficit or spondylolisthesis (Upasani et al., 2007).\n\n  5- History of spinal trauma and infection, and metabolic bone disease.",{"count":403,"type":22},34,"6 Months","Purpose of This study to detect if there is correlation between the Cobb's angle and the forward head posture in patients with Adolescent Idiopathic Scoliosis.\n\nAnd if there is correlation between the Cobb's angle and the cervical sagittal curve angle in AIS. And also if there is correlation between the Cobb's angle and deep flexors muscles endurance in AIS",[26,407],"Forward Head Posture",[409,133,410],"Forward head","craniovertebral angle","2024-10-04",{"date":413,"type":41},"2024-10-08",{"date":415,"type":22},"2024-10",{"date":340,"type":22},{"name":418,"class":48},"Cairo University"]