[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"adolescent-mental-health\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:adolescent-mental-health":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,43,75,110,138],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":42},"100622454","task-shifting-adapted-ipt-a-for-youth-suicide-prevention-100622454",false,"NCT07383831","Task-Shifting Adapted IPT-A for Youth Suicide Prevention","Youth Mentor-Led Brief Interpersonal Psychotherapy for Youth Suicide Prevention","Inclusion Criteria:\n\n1. Parent consent\n2. Adolescent consent\n3. Enrolled in youth community centers\n4. Self-identified as Hispanic or Latine\n5. Between 12 and 17 years old.\n6. Scoring threshold for depression (4-9) as indicated in the PHQ-A.\n7. No current report of suicide ideation with plan or self-harming behaviors\n\nExclusion Criteria:\n\n1. Not consented to participate in the study\n2. Scoring 10 or higher in the PHQ-A, indicating depressive disorder\n3. Active suicide ideation (i.e., having thoughts of killing oneself, thinking about how in the past month).","ALL","12 Years","17 Years",{"count":20,"type":21},46,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this randomized pragmatic clinical trial is to examine the feasibility, acceptability, and mechanisms of change of a brief adaptation of Interpersonal Psychotherapy for Adolescents (BIPT-A), adapted and task-shifted to lay providers (mentors, youth trusted adults) in youth community centers (YCCs) as an upstream approach to suicide.\n\nIt focuses on Hispanic adolescents ages 12-17 enrolled in these YCCs. The pragmatic clinical trial will evaluate the acceptability and feasibility of adapted IPT-A delivered by mentors in YCCs and whether adapted BIPT-A impacts mechanisms of change (depressive symptoms, belongingness, and burdensomeness or feeling like a burden to others).\n\nThe main questions to answer are:\n\n* Is adapted BIPT-A, when delivered by trained lay providers (youth mentors), feasible and acceptable in youth community centers?\n* Does adapted BIPT-A, delivered by lay providers, change key risk factors (i.e., key mechanisms: depressive symptoms, low belongingness, and perceived burdensomeness) associated with suicide ideation? The investigators will compare adolescents randomized to adapted BIPT-A (6 sessions) delivered by a trained youth mentor with those receiving usual services at the community center (one individual session focused on active listening).\n\nParticipants will:\n\n1. Be screened for subthreshold depression using the Patient Health Questionnaire Adolescent version (PHQ-A). Adolescent participants will be included if they score between 4 and 9 (mild depression). Participants with a PHQ-A score of 10 or higher (severe depression) will not be eligible and will be referred to a licensed mental health provider for appropriate care.\n2. Be randomized to adapted BIPT-A or usual care. Adolescent participants in the intervention arm will participate in 6 weekly, adapted BIPT-A sessions with a trained youth mentor. Intervention focuses on education, affect identification, and interpersonal skills.",[27,28,29],"Suicidal Ideation","Depressive Symptoms","Adolescent Mental Health","NOT_YET_RECRUITING","2026-05-08",{"date":33,"type":34},"2026-05-12","ACTUAL",{"date":36,"type":21},"2026-08-01",{"date":38,"type":21},"2028-07-31",{"name":40,"class":41},"Boston College","OTHER",1,{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":49,"eligibilityCriteria":50,"healthyVolunteers":11,"sex":16,"minAge":51,"maxAge":52,"enrollmentInfo":53,"targetDuration":4,"studyType":22,"phases":55,"briefSummary":56,"conditions":57,"keywords":60,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":4},"100629834","a-text-based-expressive-writing-program-for-adolescents-at-risk-of-suicide-100629834","NCT07479823","A Text-Based Expressive Writing Program for Adolescents at Risk of Suicide","Effectiveness of a Text-Based Expressive Writing Intervention for Suicidal Adolescents and Young Adults: A Randomized Controlled Trial","WRITE-SAFE","Inclusion Criteria:\n\n* Adolescents or young adults aged 13 to 24 years.\n* Individuals with a history of suicidal ideation, suicide attempts, or non-suicidal self-injury.\n* Individuals currently receiving mental health services or who have been evaluated as having suicide risk within the past 6 months.\n* Ability to read and write in Korean.\n* For participants under 19 years of age, both participant assent and parental consent are required.\n\nExclusion Criteria:\n\n* Individuals requiring immediate psychiatric hospitalization.\n* Severe intellectual disability or neurodevelopmental disorder that prevents participation in writing activities.\n* Acute psychosis or manic episode that would interfere with participation in the study.\n* Participation in another suicide prevention clinical trial during the study period.","13 Years","24 Years",{"count":54,"type":21},160,[24],"The goal of this clinical trial is to learn if a structured expressive writing program can help reduce suicidal thoughts in adolescents and young adults who have experienced suicidal thoughts, suicide attempts, or self-harm. The study will include participants aged 13 to 24 years who are receiving mental health care or have recently been identified as being at risk for suicide.\n\nThe main questions the study aims to answer are:\n\n* Does a structured expressive writing program lower suicidal thoughts compared with usual care alone?\n* Does the program improve depression, impulsivity, and self-esteem?\n\nResearchers will compare participants who receive the expressive writing program together with treatment as usual to participants who receive treatment as usual alone.\n\nParticipants will:\n\n* Be randomly assigned to one of two groups: a writing program group or a usual care group\n* Complete questionnaires about mood, suicidal thoughts, and well-being at the start of the study, after 4 weeks, and after 8 weeks\n* If assigned to the writing program group, complete guided writing activities several times per week for 4 weeks. Each writing session will take about 15 to 20 minutes and will focus on understanding emotions, personal experiences, relationships, and meaning in difficult experiences.\n\nResearchers will study whether this writing program is a helpful and practical way to support young people who are experiencing suicidal thoughts or emotional distress.",[27,58,59,29],"Suicide Risk","Self-Injurious Behavior",[61,62,63,64,65],"Expressive Writing","Suicide Prevention","Adolescent Suicide","Self-Harm","Youth Mental Health","2026-03-13",{"date":68,"type":34},"2026-03-18",{"date":70,"type":21},"2026-04-01",{"date":72,"type":21},"2028-03",{"name":74,"class":41},"Hallym University Medical Center",{"id":76,"slug":77,"hasResults":11,"nctId":78,"briefTitle":79,"officialTitle":80,"acronym":4,"eligibilityCriteria":81,"healthyVolunteers":82,"sex":16,"minAge":83,"maxAge":84,"enrollmentInfo":85,"targetDuration":4,"studyType":22,"phases":87,"briefSummary":88,"conditions":89,"keywords":92,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":101,"lastUpdatePostDateStruct":102,"startDateStruct":104,"completionDateStruct":106,"leadSponsor":108,"locationsCount":42},"100628360","a-virtual-reality-e-cigarette-prevention-and-emotion-regulation-intervention-for-adolescents-100628360","NCT07460622","A Virtual Reality E-cigarette Prevention and Emotion Regulation Intervention for Adolescents","E-cigarette Prevention and Emotion Regulation: Virtual Reality Intervention for Adolescents","Inclusion Criteria\n\n* Enrolled in the 8th grade in one of the 20 partner middle schools (8 in Connecticut, 12 in Massachusetts).\n* Willing to participate in a VR videogame for approximately 45 minutes per session, accumulating 2-2.5 hours of total gameplay across multiple class periods.\n* Able to provide assent and obtain parental\u002Fguardian consent before participating in the study.\n\nExclusion Criteria\n\n* Students not enrolled in 8th grade at one of the participating schools.\n* Students who are unwilling or unable to participate in VR gameplay for the required duration.\n* Students who cannot provide assent or do not have parental\u002Fguardian consent to participate .",true,"11 Years","15 Years",{"count":86,"type":21},1251,[24],"This study will examine E-Invite Only VR, a novel school-based universal e-cigarette prevention intervention that uses virtual reality (VR) to deliver prevention and emotion regulation skills-building content to middle school students in real-world classrooms. If successful, E-invite Only VR has the potential to prevent adolescents from experiencing a multitude of poor health outcomes related to nicotine vaping, including cancer.",[90,91,29],"E-cigarette Use\u002FVaping Prevention","Nicotine Dependence Prevention",[93,94,95,96,97,98,99,100],"E-cigarette prevention","Vaping prevention","Nicotine addiction prevention","Virtual reality intervention","School-based prevention program","Mental health and substance use","Digital health intervention","emotion regulation skills","2026-03-03",{"date":103,"type":34},"2026-03-10",{"date":105,"type":21},"2026-10-01",{"date":107,"type":21},"2028-06",{"name":109,"class":41},"Yale University",{"id":111,"slug":112,"hasResults":11,"nctId":113,"briefTitle":114,"officialTitle":115,"acronym":4,"eligibilityCriteria":116,"healthyVolunteers":82,"sex":16,"minAge":51,"maxAge":117,"enrollmentInfo":118,"targetDuration":4,"studyType":22,"phases":120,"briefSummary":121,"conditions":122,"keywords":127,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":129,"lastUpdatePostDateStruct":130,"startDateStruct":132,"completionDateStruct":134,"leadSponsor":136,"locationsCount":4},"100623331","mental-health-literacy-and-help-seeking-behavior-among-adolescents-100623331","NCT07395245","Mental Health Literacy and Help-Seeking Behavior Among Adolescents","Mental Health Literacy and Help-Seeking Behavior Among Adolescents in Assiut City: An Interventional Study","Inclusion Criteria:\n\n* Adolescents aged 13-18 years.\n* Enrolled in selected schools in Assiut city\n\nExclusion Criteria:\n\n* Documented severe intellectual disability or learning difficulty that, in the judgement of school staff, would prevent understanding of the intervention content or valid questionnaire completion.\n* Current acute medical or psychiatric emergency at the time of data collection as identified by school or health-center staff.\n* Refusal of participation by the student, or absence of parental consent.","18 Years",{"count":119,"type":21},150,[24],"This study examines mental health awareness and help-seeking behaviors among adolescents aged 13-18 years in Assiut City, Egypt. Mental health problems are common among young people, but many adolescents do not seek professional help when they need it. This is often due to low mental health literacy (not understanding mental health problems or knowing where to get help), stigma (negative attitudes toward mental illness), and fears about confidentiality or being judged.\n\nThe study has two parts:\n\nPart 1 - Assessment Phase: Researchers will survey approximately 270 students from preparatory and secondary schools in Assiut to understand their current levels of mental health literacy, stigma, and willingness to seek help for mental health problems. Students will complete validated questionnaires that measure their knowledge about mental health, their attitudes toward peers with mental health problems, and their intentions to seek help from various sources.\n\nPart 2 - Intervention Phase: In a randomized controlled trial involving 150 students (75 in an intervention group and 75 in a control group), researchers will test whether a brief educational program can improve mental health literacy, reduce stigma, and increase help-seeking intentions. The intervention consists of three weekly classroom sessions covering: (1) mental health literacy - basic concepts, common problems in adolescents like stress and anxiety, recognizing symptoms; (2) stigma reduction - understanding how negative labels hurt people, recognizing public and self-stigma, using respectful language; and (3) help-seeking behavior - knowing when to seek help, understanding formal and informal help sources, overcoming barriers, and learning about local resources in Assiut.\n\nStudents in both groups will complete questionnaires before the intervention and one month after completion. The control group will not receive the educational sessions during the study period. Researchers will compare changes in mental health knowledge, stigma levels, and help-seeking attitudes between the two groups to determine whether the program is effective.\n\nThe study aims to address a critical gap in mental health services for adolescents in Upper Egypt by improving young people's understanding of mental health and encouraging them to seek appropriate help when needed.",[123,124,125,126,29],"Mental Health","Mental Health Literacy","Stigma of Mental Illness","Help-Seeking Behavior",[124,126,29,128],"Stigma","2026-02-02",{"date":131,"type":34},"2026-02-09",{"date":133,"type":21},"2026-05",{"date":135,"type":21},"2027-06",{"name":137,"class":41},"Assiut University",{"id":139,"slug":140,"hasResults":11,"nctId":141,"briefTitle":142,"officialTitle":143,"acronym":4,"eligibilityCriteria":144,"healthyVolunteers":82,"sex":16,"minAge":17,"maxAge":145,"enrollmentInfo":146,"targetDuration":4,"studyType":22,"phases":148,"briefSummary":149,"conditions":150,"keywords":154,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":171,"lastUpdatePostDateStruct":172,"startDateStruct":174,"completionDateStruct":176,"leadSponsor":177,"locationsCount":4},"100592640","effects-of-a-multifaceted-school-based-intervention-to-protect-mental-health-and-prevent-suicidal-behaviour-in-adolescents-in-spain-100592640","NCT06996054","Effects of a Multifaceted School-Based Intervention to Protect Mental Health and Prevent Suicidal Behaviour in Adolescents in Spain","DEVELOPMENT AND EVALUATION OF A MULTIFACETED SCHOOL-BASED INTERVENTION TO PROTECT MENTAL HEALTH AND PREVENT SUICIDAL BEHAVIOR AMONG ADOLESCENTS IN SPAIN","Inclusion Criteria:\n\n* Students enrolled in the 2nd or 3rd year of compulsory secondary education during the 2026-2027 academic year in the Balearic Islands, Spain.\n* Aged between 12 and 16 years at the time of recruitment.\n* Provision of written informed consent from both the student and at least one parent\u002Flegal guardian.\n* Attending school centres with a student population composed of no more than 75% of a single gender.\n* Enrollment in a participating classroom randomly selected for the study.\n\nExclusion Criteria:\n\n* Presence of cognitive, developmental, or language impairments that, in the judgment of school staff or study personnel, would prevent the student from understanding the intervention content or completing the study assessments reliably.\n* Students currently receiving intensive psychological or psychiatric treatment for acute suicidality or severe mental health conditions that require individualized clinical management beyond the scope of a school-based programme.\n* Students or parents who explicitly decline participation in specific intervention components, such as group discussions on suicide or mental health.\n* Participation in a concurrent school-based mental health programme that could confound the effects of the intervention.","16 Years",{"count":147,"type":21},2280,[24],"What is this study about? This study aims to find out if a school-based program can help improve mental health and prevent suicidal thoughts and behaviors in teenagers in Spain. Suicide is one of the leading causes of death among young people. Many teens who think about or attempt suicide are also struggling with mental health problems like depression. Schools offer a unique opportunity to help because almost all adolescents attend school regularly.\n\nWhat will happen in the study?\n\nThe study will include about 2,280 students aged 12 to 16 years from 38 secondary schools in the Balearic Islands, Spain. Schools will be randomly assigned to one of two groups:\n\nIntervention group: Students will participate in four weekly classroom sessions led by trained psychologists. These sessions will help students learn about mental health, manage their emotions, recognize signs of distress in themselves or others, and ask for help when needed. At the same time, parents and teachers will follow a digital training program with videos and resources to help them support students' mental health and recognize warning signs.\n\nControl group: Students will receive a minimal intervention, which includes educational posters displayed in classrooms.\n\nWhat is the purpose of this program? The main goal is to reduce suicidal thoughts and behaviors. The program also aims to improve students' overall mental well-being, reduce depression symptoms, and encourage help-seeking behaviors. It also helps parents and teachers feel more confident in supporting teens who may be at risk.\n\nHow will the study be evaluated? Students will complete questionnaires at the start of the study and again after six months. These surveys will ask about mental health, suicidal thoughts, emotional well-being, self-harm, substance use, and experiences with bullying. Parents and teachers will also complete surveys about their knowledge and confidence in supporting students.\n\nWhy is this study important? There is an urgent need to find effective ways to prevent suicide and support young people's mental health. This program involves students, families, and schools in working together to create a safe and supportive environment. If the program works, it could be used in schools throughout Spain and possibly in other countries too.\n\nWho is funding this study? The study is funded by Fundación Mutua Madrileña.",[151,152,29,64,153],"Suicide Attempt","Depression","Suicidal Ideation and Behavior",[155,156,157,158,152,159,160,161,162,163,164,165,166,167,168,169,170],"School-based intervention","Suicide prevention","Suicidal ideation","Suicidal behavior","Adolescents","Mental health promotion","Psychoeducation","Gatekeeper training","Teachers","Parents","Digital health","Cluster randomized controlled trial","Spain","Secondary education","Emotional regulation","Self-harm","2025-05-21",{"date":173,"type":34},"2025-05-30",{"date":175,"type":21},"2025-10",{"date":135,"type":21},{"name":178,"class":179},"Fundació d'investigació Sanitària de les Illes Balears","OTHER_GOV"]