[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"adults-with-repaired-tetralogy-of-fallot\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:adults-with-repaired-tetralogy-of-fallot":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":4},"100618023","effect-of-exercises-on-ventilatory-function-in-adult-with-tof-100618023",false,"NCT07326228","Effect of Exercises on Ventilatory Function in Adult With TOF","Effect of Combined Inspiratory Muscle Training and Aerobic Exercises on Ventilatory Function in Adults With Repaired Tetralogy of Fallot","Inclusion Criteria:\n\n* Diagnosed with TOF.\n* Have surgical correction of the abnormality.\n* Class II-III according to New York Heart Association (NYHA)\n* Ejection fracture \\> 40\n* Vitally stable during the study period\n\nExclusion Criteria:\n\n* Resent cardiopulmonary surgery or intervention \"less than 6 months\"\n* Presence of pulmonary disease which is not a complication of TOF (eg:\n\nbronchial asthma, lung fibrosis…..)\n\n* Neuromuscular or musculoskeletal disease and severe scoliosis affecting pulmonary function or physical exercise.\n* Mental or physical limitations\n* active infection or systemic illness.\n* Hemodynamic instability\n* Mouth burn, injury, or deformities\n* Implanted pacemaker","ALL","18 Years","30 Years",{"count":20,"type":21},60,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this clinical trial is to learn if combined inspiratory muscle training and aerobic exercise can improve ventilatory function in adults with repaired Tetralogy of Fallot (TOF). It will also learn if exercises work to raise functional capacity and Quality of life (QoL) . The main questions it aims to answer is:\n\n* Dose combined inspiratory muscle training and aerobic exercise (study group) improve ventilatory function in adults with repaired (TOF) more than aerobic exercise only (control group)?\n* Can combine inspiratory muscle training and aerobic exercise (study group) raise functional capacity and (QoL) in adults with repaired (TOF) more than aerobic exercise only (control group)?\n\nResearchers will compare between combination of inspiratory muscle training and aerobic exercise on one group and the aerobic exercise only on other group, on ventilatory function, functional capacity and (QoL) on adults with repaired TOF.\n\nParticipants will:\n\nOn study group , participants will perform respiratory muscle training in addition to moderate intensity aerobic exercise for 6 weeks. 3 times\u002Fweek\n\nOn controlled group , participants will perform moderate intensity aerobic exercise for 6 weeks. 3 times\u002Fweek.\n\nall participants will test ventilatory function , functional capacity and will answer a survey questions about their quality of life before and after training",[27,28],"Tetralogy of Fallot (TOF)","Adults With Repaired Tetralogy of Fallot",[30,31,32,33,34,35,36],"congenital heart disease","tetralogy of Fallot","inspiratory muscle training","aerobic exercise","ventilatory functions","functional capacity","Quality of life","NOT_YET_RECRUITING","2025-12-24",{"date":40,"type":41},"2026-01-08","ACTUAL",{"date":43,"type":21},"2026-01-01",{"date":45,"type":21},"2027-01-31",{"name":47,"class":48},"Cairo University","OTHER"]