[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"advance-care-planning\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:advance-care-planning":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,12,0,[8,41,66,111,135,155,177,209,240,274,311,341],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":40},"100557467","jumpstarting-advance-care-planning-with-anai-people-100557467",false,"NCT06538493","Jumpstarting Advance Care Planning With ANAI People","Jumpstarting Culturally-informed Advance Care Planning With ANAI People in Primary Care","JUMP","Inclusion Criteria:\n\nAge 40 or older with a qualifying serious illness condition (e.g., COPD) OR Age 65 or older (regardless of diagnosis) AND Alaska Native and\u002For American Indian AND Empaneled to a primary care provider AND 2 or more to primary care in last 12 months AND No advance directives documented in electronic health record\n\nExclusion Criteria:\n\nUnable to provide informed consent AND\u002FOR Not able to complete 30-minute study visit by phone, video call, or in person","ALL","40 Years",{"count":20,"type":21},400,"ESTIMATED","INTERVENTIONAL",[24],"NA","The older Alaska Native\u002FAmerican Indian (ANAI) population is increasing at twice the rate of the general population with a higher burden of serious illness. Older ANAI adults with serious illness are half as likely to have advance directives (AD), indicating a need for improved access to and utilization of advance care planning (ACP) to ensure that medical care aligns with the values, goals, and preferences of ANAI patients and their families throughout the illness trajectory. The major goals of this cluster randomized trial (CRT) are to (1) evaluate the comparative effectiveness of usual care and JUMPSTART- ANAI, a culturally tailored ACP communication intervention, for prompting patient-driven ACP conversations between ANAI adults and primary care providers and to (1) identify key factors to successfully implement the intervention in health systems serving ANAI adults with serious illness.",[27],"Advance Care Planning","RECRUITING","2026-06-11",{"date":31,"type":32},"2026-06-15","ACTUAL",{"date":34,"type":32},"2025-04-01",{"date":36,"type":21},"2027-05-31",{"name":38,"class":39},"Southcentral Foundation","OTHER",1,{"id":42,"slug":43,"hasResults":11,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":4,"eligibilityCriteria":47,"healthyVolunteers":48,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":49,"targetDuration":4,"studyType":22,"phases":51,"briefSummary":52,"conditions":53,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":57,"lastUpdatePostDateStruct":58,"startDateStruct":60,"completionDateStruct":62,"leadSponsor":64,"locationsCount":40},"100523024","motivational-interviewing-to-enhance-advance-care-planning-for-older-adults-and-caregivers-after-emergency-visits-100523024","NCT06090240","Motivational Interviewing to Enhance Advance Care Planning for Older Adults and Caregivers After Emergency Visits","Maximizing Teachable Moments: Motivational Interviewing (MI) to Enhance Advance Care Planning (ACP) for Older Adults and Caregivers After Emergency Visits - A Mixed-Method Randomized Controlled Trial","The target group will be dyads comprising older adults who have had ER visits within the previous six months and their family caregivers. A dyad is defined as one older adult and one primary family caregiver of the older adult.\n\nFor older adults:\n\nInclusion Criteria:\n\n* Aged 65 or older\n* At least one episode of ER visit in the last six months\n* Has a family caregiver to be present during the intervention\n* Able to communicate in Chinese\n\nExclusion Criteria:\n\n* Has completion of an AD\n* Moderate to severe cognitive impairment or diagnosis of dementia, as identified in health records\n* Communication problems (e.g., deafness or aphasia)\n\nFor family caregivers:\n\nInclusion Criteria:\n\n* Aged 18 or above\n* Immediate or extended family member or friend nominated by an eligible older adult participant as primary caregiver\n* Able to communicate in Chinese\n\nExclusion Criteria:\n\n* Moderate to severe cognitive impairment\n* Communication problems (e.g., deafness or aphasia)",true,{"count":50,"type":21},300,[24],"This study aims to evaluate the effectiveness of a motivational interviewing (MI) intervention in enhancing advance care planning (ACP) among older adults who have visited the Emergency Room (ER) in the past six months and their family caregivers. The main question it aims to answer is: The effectiveness of the MI-based ACP intervention implemented within six months of an ER visit on improving older adults' advance directives (AD) completion rate.\n\nCompared to participants in the control group who will only receive a self-education booklet, participants in the intervention group will receive a motivational interview educational intervention to see the effectiveness of an MI-based ACP intervention implemented within six months following an emergency room visit regarding the completion of AD for older adults.",[54,27,55,56],"Older Adults","Advance Directives","Family Members","2026-05-28",{"date":59,"type":32},"2026-06-02",{"date":61,"type":32},"2023-12-14",{"date":63,"type":21},"2027-07-31",{"name":65,"class":39},"The University of Hong Kong",{"id":67,"slug":68,"hasResults":11,"nctId":69,"briefTitle":70,"officialTitle":71,"acronym":72,"eligibilityCriteria":73,"healthyVolunteers":48,"sex":17,"minAge":74,"maxAge":4,"enrollmentInfo":75,"targetDuration":4,"studyType":22,"phases":77,"briefSummary":78,"conditions":79,"keywords":95,"overallStatus":101,"whyStopped":4,"lastUpdateSubmitDate":102,"lastUpdatePostDateStruct":103,"startDateStruct":105,"completionDateStruct":107,"leadSponsor":109,"locationsCount":4},"100619558","communityrx-dementia--peer-navigation-crxdpeer-100619558","NCT07346183","CommunityRx-Dementia + Peer Navigation (CRxDpeer)","CommunityRx-Dementia + Peer Navigation (CRxDpeer): A Real-World Implementation and Effectiveness Study of an IT-Based Social Care Intervention","CRxDpeer","Inclusion Criteria:\n\n* Self-identifies as a caregiver of a home-dwelling person with Alzheimer's disease or related dementias (ADRD)\n* Resides in the target geographic region of the study\n* Has access to a cell phone and agrees to receive text messages from the study\n* Has an email address that they can receive emails from\n* Individuals under the age of 18 who are emancipated minors in the state of Illinois and a caregiver of a person with dementia\n\nExclusion Criteria:\n\n* Minors who are not emancipated in the state of Illinois.\n* Previously participated in the intervention arm of the CommunityRx-Dementia clinical trial","18 Years",{"count":76,"type":21},330,[24],"The CRxDpeer intervention, delivered by a trained peer navigator, in practice called a \"peer mentor\", includes three evidence-based components: (a) focused education about common social (e.g., food and housing insecurity) and caregiving (e.g., respite and end of life care) needs, (b) activation of personalized community resource information for social and caregiving needs through delivery of a resource list (HealtheRx) at the baseline encounter and coaching on how to communicate with service providers, coordinate services and manage social support (e.g., connect with their peer navigator, reach out to friends or relatives for support, identify support groups, etc.) and (c) ongoing navigation-focused support meant to boost the baseline intervention, including a series of proactive text messages over 12 months. During this time, the subject can respond to and communicate with the peer navigator for ongoing support.",[80,81,82,83,84,85,86,87,88,89,90,91,92,93,94,27],"Alzheimer s Disease","Dementia","Caregiver","Loneliness","Health-Related Social Needs","Social Care","Healthcare Utilization","End of Life Care","Caregiver Burden","Anxiety","Stress","Depression","Self-Efficacy","Peer Support","Implementation Science",[96,97,98,99,100],"resource navigation","peer navigator","peer mentor","social care","dementia caregiver","NOT_YET_RECRUITING","2026-04-06",{"date":104,"type":32},"2026-04-07",{"date":106,"type":21},"2026-06-01",{"date":108,"type":21},"2029-02-28",{"name":110,"class":39},"University of Chicago",{"id":112,"slug":113,"hasResults":11,"nctId":114,"briefTitle":115,"officialTitle":115,"acronym":4,"eligibilityCriteria":116,"healthyVolunteers":48,"sex":17,"minAge":74,"maxAge":4,"enrollmentInfo":117,"targetDuration":4,"studyType":22,"phases":119,"briefSummary":120,"conditions":121,"keywords":124,"overallStatus":101,"whyStopped":4,"lastUpdateSubmitDate":126,"lastUpdatePostDateStruct":127,"startDateStruct":129,"completionDateStruct":131,"leadSponsor":133,"locationsCount":4},"100626727","using-a-conversation-game-to-engage-native-american-washoe-tribe-members-in-advance-care-planning-preparation-for-a-clinical-trial-100626727","NCT07439393","Using a Conversation Game to Engage Native American Washoe Tribe Members in Advance Care Planning: Preparation for a Clinical Trial","Inclusion Criteria:\n\n* Age 18 years or older\n* Member of the Washoe American Indian Tribe\n* Able to attend in-person events\n* Speaks, reads, and writes in English\n* Able to provide informed consent\n\nExclusion Criteria:\n\n* Under 18 years of age\n* Non-Tribal member\n* Non-English speaking\n* Unable to provide informed consent",{"count":118,"type":21},108,[24],"The goal of this study is to learn if a culturally adapted version of the Hello game, an advance care planning (ACP) conversation tool, is feasible and acceptable for use with members of the Washoe Tribe. The main questions it aims to answer are:\n\nCan the Hello game be successfully adapted to reflect the cultural values, beliefs, and storytelling traditions of the Washoe Tribe?\n\nDoes playing the adapted Hello game increase ACP engagement and advance directive (AD) completion among Washoe Tribe members within 3 months?\n\nParticipants will:\n\n* Take part in talking circles at one of four Washoe reservations to share their beliefs, motivations, and experiences related to end-of-life care and advance care planning\n* Complete brief questionnaires about their ACP attitudes and behaviors\n* Play the culturally adapted Hello game in a group setting\n* Complete follow-up measures of ACP engagement and advance directive completion 3 months after playing the game",[27,122,123],"American Indian or Alaska Native","Gamification",[125,122,123],"Advance care planning","2026-02-26",{"date":128,"type":32},"2026-03-02",{"date":130,"type":21},"2026-06",{"date":132,"type":21},"2028-09",{"name":134,"class":39},"Milton S. Hershey Medical Center",{"id":136,"slug":137,"hasResults":11,"nctId":138,"briefTitle":139,"officialTitle":140,"acronym":141,"eligibilityCriteria":142,"healthyVolunteers":11,"sex":17,"minAge":74,"maxAge":4,"enrollmentInfo":143,"targetDuration":4,"studyType":22,"phases":145,"briefSummary":146,"conditions":147,"keywords":4,"overallStatus":101,"whyStopped":4,"lastUpdateSubmitDate":126,"lastUpdatePostDateStruct":148,"startDateStruct":150,"completionDateStruct":152,"leadSponsor":154,"locationsCount":4},"100627439","chatbot-assisted-advance-care-planning-education-for-family-members-100627439","NCT07448649","Chatbot-Assisted Advance Care Planning Education for Family Members","Messaging-and-chatbot-assisted Nursing Consultation to Empower Family Members of Residents Living in Nursing Homes on Advance Care Planning (ChatACP)","ChatACP","Inclusion Criteria:\n\n* aged 18 years or older\n* providing care for an older adult (age 65 or above) living in a care home as a family member (including the family members in the traditional sense and the guardian and persons close to or significant to the older adult)\n* able to read, write and communicate in Cantonese or Mandarin\n* the resident, care recipient, having a prefrail or frail status as defined by a score of 3 or above on the Clinical Frailty Scale (CFS)\n* having a mobile device to receive instant messages and access to cellular network\n* engaged in minimal or no prior EOL care discussions with the care home resident as defined by a self-reported status of pre contemplation\u002Fcontemplation stage on ACP discussions with the resident using the ACP staging algorithm\n\nExclusion Criteria:\n\n* suffering from moderate to severe cognitive impairment defined by an Abbreviated Mental Test score of 5 or less and unable to give consent\n* suffering from communication problems (e.g., deafness or aphasia)",{"count":144,"type":21},60,[24],"The goal of this clinical trial is to learn if a messaging and chatbot program, called ChatACP, helps family members of people living in nursing homes take part in advance care planning.\n\nThe main questions this study aims to answer are:\n\n* Does ChatACP help family members feel more ready to talk about future medical and personal care with their loved one?\n* Does ChatACP help family members take part in advance care planning activities, such as having care discussions or completing planning documents?\n* Is ChatACP easy to use and acceptable for family members?\n\nResearchers will compare ChatACP to standard self-learning materials about advance care planning to see which approach works better.\n\nParticipants will:\n\n* Receive short daily messages with pictures or videos about advance care planning and access to a chatbot specialized in ACP for 10 days\n* Complete surveys at the start of the study, after the program ends, and again 3 months later\n* Take part in an interview to share their experience with the program",[27],{"date":149,"type":32},"2026-03-04",{"date":151,"type":21},"2026-06-30",{"date":153,"type":21},"2028-06-30",{"name":65,"class":39},{"id":156,"slug":157,"hasResults":11,"nctId":158,"briefTitle":159,"officialTitle":160,"acronym":4,"eligibilityCriteria":161,"healthyVolunteers":11,"sex":17,"minAge":74,"maxAge":162,"enrollmentInfo":163,"targetDuration":4,"studyType":165,"phases":4,"briefSummary":166,"conditions":167,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":169,"lastUpdatePostDateStruct":170,"startDateStruct":172,"completionDateStruct":174,"leadSponsor":175,"locationsCount":40},"100518823","resilience-in-east-asian-immigrants-for-advance-care-planning-discussions-100518823","NCT06035549","Resilience in East Asian Immigrants for Advance Care Planning Discussions","Development of a Culturally Tailored Digital Resilience-Building Intervention for East Asian Immigrants With Cancer to Facilitate Advance Care Planning Discussions","Inclusion Criteria for Religious Leaders:\n\n* Age ≥ 18 years\n* Serving as a chaplain or religious leader at a healthcare setting or religious organization\n* Having experience providing pastoral or spiritual care to Chinese, Japanese, and Korean Americans in the US\n* Being able to read and respond to questions in English, Mandarin, Cantonese, Japanese, or Korean.\n\nExclusion criteria: Not willing to provide consent.\n\nInclusion Criteria for Patients:\n\n* Age ≥ 18 years\n* Having a cancer diagnosis\n* Likely self-identifying as a Chinese, Japanese, or Korean American\u002Fimmigrant\n* Being able to read and respond to questions in either English, Mandarin, Japanese, Korean, or Chinese dialects, such as Cantonese, Shanghai, Taishanese, or Taiwanese.\n\nExclusion Criteria for Patients:\n\n* Having cognitive impairment per the Short Portable Mental Status Questionnaire with more than three errors\n\nInclusion Criteria for Family Caregivers:\n\n* Age ≥ 18 years\n* Being able to read and respond to questions in either English, Mandarin, Japanese, Korean, or Chinese dialects, such as Cantonese, Shanghai, Taishanese, or Taiwanese\n* Having a family member who is likely to self-identify as a Chinese, Japanese, or Korean American\u002Fimmigrant and has been diagnosed with cancer","80 Years",{"count":164,"type":21},84,"OBSERVATIONAL","The purpose of the study is to develop a culturally tailored digital resilience-building intervention to help East Asian immigrants engage in advance care planning discussions with their family caregivers.",[168,27],"Neoplasms","2026-02-16",{"date":171,"type":32},"2026-02-18",{"date":173,"type":32},"2023-10-27",{"date":151,"type":21},{"name":176,"class":39},"University of Illinois at Chicago",{"id":178,"slug":179,"hasResults":11,"nctId":180,"briefTitle":181,"officialTitle":182,"acronym":183,"eligibilityCriteria":184,"healthyVolunteers":48,"sex":17,"minAge":185,"maxAge":4,"enrollmentInfo":186,"targetDuration":4,"studyType":22,"phases":188,"briefSummary":189,"conditions":190,"keywords":191,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":199,"lastUpdatePostDateStruct":200,"startDateStruct":202,"completionDateStruct":204,"leadSponsor":206,"locationsCount":208},"100534520","advance-care-planning-with-formerly-homeless-older-adults-residing-in-permanent-supportive-housing-100534520","NCT06239896","Advance Care Planning With Formerly Homeless Older Adults Residing in Permanent Supportive Housing","Empowering Formerly Homeless Older Adults to Engage in Advance Care Planning in Permanent Supportive Housing (ACP-PSH): An RCT","ACP-PSH","Inclusion Criteria:\n\n* Formerly chronically homeless adults living in permanent supportive housing\n* English speaking\n\nExclusion Criteria:\n\n* Non-English Speaking\n* Screen positive for moderate-to-severe cognitive impairment\n* Self-report being deaf or blind\n* Cannot provide informed consent based on the teach back method","50 Years",{"count":187,"type":21},650,[24],"The homeless population is aging, with an increasing proportion of individuals over age 50 who experience accelerated aging, high rates of mortality, and a high risk of not having their wishes honored at the end of life. The goal of this randomized control trial (RCT) is to test the effectiveness of adapted evidence-based advance care planning (ACP) interventions for formerly chronically homeless older adults living in permanent supportive housing (PSH).",[27],[27,192,193,194,195,196,197,87,198],"Formerly Chronically Homeless","Older Adult","Permanent Supportive Housing","Homelessness","Aging Population","Decision Making","Medical Decisions","2025-11-17",{"date":201,"type":32},"2025-11-20",{"date":203,"type":32},"2024-03-06",{"date":205,"type":21},"2027-03",{"name":207,"class":39},"University of California, San Francisco",6,{"id":210,"slug":211,"hasResults":11,"nctId":212,"briefTitle":213,"officialTitle":214,"acronym":4,"eligibilityCriteria":215,"healthyVolunteers":11,"sex":17,"minAge":216,"maxAge":4,"enrollmentInfo":217,"targetDuration":4,"studyType":22,"phases":219,"briefSummary":220,"conditions":221,"keywords":226,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":232,"lastUpdatePostDateStruct":233,"startDateStruct":235,"completionDateStruct":237,"leadSponsor":238,"locationsCount":40},"100603312","navigating-advanced-illness-goals-and-treatment-with-digital-engagement-navigate-100603312","NCT07134881","Navigating Advanced Illness Goals And Treatment With Digital Engagement (NAVIGATE)","Navigating Advanced Illness Goals And Treatment With Digital Engagement (NAVIGATE): A Randomised Control Trial","1\\. Patient Participants Inclusion Criteria:\n\n1. Singapore resident aged 21years and above,\n2. patient able to identify one main caregiver in the care and medical decision-making for the patient;\n3. patient able to communicate in either English, Chinese, Malay or Tamil;\n4. patient meeting one of the following illness criteria: 4a. Patients with brain tumours: histological and\u002For radiological diagnosis of glioma or brain metastases.\n\n4b. Patients with spontaneous intracerebral haemorrhage (SICH) based on radiological diagnosis of SICH on baseline computed-tomographic scans.\n\n4c. Patients with CKD Stage 4 and 5, identified at G4 or G5 of CKD, glomerular filtration rate (GFR) 30 ml\u002Fmin or less, inclusive of kidney failure on kidney replacement therapy; and (5) Physicians assessment that ACP is appropriate for the patient by physicians.\\* (\\*) The attending clinicians may base the assessment of ACP appropriateness on several factors in addition to high mortality risk. As a baseline, clinicians are asked to base their assessment of high mortality risk using the validated \"Surprise\" question.\n\n2\\. Patient participants Exclusion Criteria:\n\n1. Patients unable to identify a caregiver who is a medical decision-maker,\n2. Patients are currently or was previously healthcare workers; or\n3. Patients are diagnosed with dementia or deemed cognitively impaired as determined by the Abbreviated Mental Test.\n\n3\\. Caregiver Participants Inclusion Criteria:\n\n1. caregivers are identified as a medical decision-maker for the patient\n2. Singapore resident aged 21 years and above; and\n3. able to communicate in English\n\n4\\. Caregiver Participants Exclusion Criteria:\n\n1. caregivers are currently or were previously healthcare workers;\n2. caregivers not involved in primary care of the patient (including providing care to the patient, supervision of care, or involved in making decisions regarding treatment the patient receives); or\n3. caregivers diagnosed with dementia.","21 Years",{"count":218,"type":21},200,[24],"The goal of this two-armed, parallel-design, pre-\u002Fpost-intervention assessment clinical trial is to learn if a digital and interactive website helps to improve advance care planning (ACP) engagement among caregivers of patients with serious illness. The main questions it aims to answer are:\n\nDoes the website increase ACP engagement of caregivers of patients with serious illness? Researchers will compare the digital and interactive website to the usual care (a digital booklet) to see if the digital intervention works to improve ACP engagement among caregivers.\n\nParticipants who are caregivers will:\n\n* Be introduced to a digital website and asked to explore the site over the course of the study.\n* Complete four self-administered questionnaires (baseline, one-week, six-week, and six-month).\n\nParticipants who are patients will not have any intervention assigned and will only have their observational data collected through four interviewer-administered questionnaires (baseline, one-week, six-week, and six-month)",[222,27,223,224,225],"Paliative Care","Digital Education Interventions","Values, Social","Goals of Care",[227,228,229,230,231],"randomised control trial","digital intervention","advance care planning","goals of care","palliative care","2025-09-12",{"date":234,"type":32},"2025-09-15",{"date":236,"type":32},"2025-08-27",{"date":63,"type":21},{"name":239,"class":39},"National University of Singapore",{"id":241,"slug":242,"hasResults":11,"nctId":243,"briefTitle":244,"officialTitle":245,"acronym":4,"eligibilityCriteria":246,"healthyVolunteers":11,"sex":17,"minAge":247,"maxAge":4,"enrollmentInfo":248,"targetDuration":4,"studyType":22,"phases":250,"briefSummary":251,"conditions":252,"keywords":253,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":265,"lastUpdatePostDateStruct":266,"startDateStruct":268,"completionDateStruct":270,"leadSponsor":272,"locationsCount":5},"100491627","advanced-care-planning-for-the-severely-ill-home-dwelling-elderly-100491627","NCT05681585","Advanced Care Planning for the Severely Ill Home-dwelling Elderly","Implementing Advanced Care Planning in the Routine Care for Acutely Admitted Patients in Geriatric Units: a Cluster Randomised Controlled Trial","Inclusion and exclusion criteria for patients and relatives the quantitative and triadic sub-study:\n\nInclusion criteria for patients:\n\n* Home-dwelling\n* 70 years or older\n* Acutely admitted to the participating unit\n* Sufficient language proficiency in Norwegian to answer the questionnaire\n* Clinical frailty score of 4 or more\n* The physician responsible for the patient's medical care answers \"no\" to \"Surprise question\" from Gold Standards Framework proactive identification guidance\n* Both patient and a close relative (preferably the closest relative) would participate in ACP together if offered\n* Both patient and the close relative consent to participate in the research project\n\nExclusion criteria for patients:\n\n* The patient is not competent to consent to research participation\n* The patient is expected to die within 24 hours\n* The patient has participated in ACP prior to the current hospital admission\n* In the intervention arm\n\n  * ACP is not conducted with patient, next of kin and physician before hospital discharge\n  * The clinician that participated in the ACP conversation has not consented to research participation\n* In the control arm\n\n  * The patient would not have been able to participate in ACP during hospitalization\n  * An attending clinician has not consented to research participation\n\nInclusion criteria for relatives:\n\n* A close relative of a patient who fulfill all inclusion criteria and no exclusion criteria; and who would be willing to participate in ACP together with the patient if offered\n* 18 years or older\n* Sufficient language proficiency in Norwegian to answer the questionnaire\n* Both patient and the close relative consent to participate in the research project\n\nExclusion criteria for relatives:\n\n* The relative is not competent to consent to research participation\n* In the intervention arm\n\n  * ACP is not carried out with the patient, next of kin and attending clinician before hospital discharge\n* In the control arm\n\n  * The relative would not have been able to participate in ACP during hospitalization","70 Years",{"count":249,"type":21},2000,[24],"This study will develop and evaluate a complex intervention to implement advance care planning for severely ill home-dwelling elderly acutely admitted to hospital, by using a cluster randomized design.\n\nTwelve Norwegian acute geriatric hospital units will participate in the main study, each as one cluster. Of the twelve clusters, half will receive implementation support and training immediately, and the other half will receive similar support after the intervention period. The study includes 1) assessment of implementation outcomes (fidelity) in the participating units,2) health service and clinical outcomes including a) questionnaires to all staff in the units before and after the implementation period, questionnaires to attending clinicians and qualitative interviews with health personnel and local unit leaders b) questionnaires to patients and their relatives, patients records and data from central health registers and qualitative interviews with patients and relatives. Furthermore we will assess barriers and facilitators for advance care planning in 1) a wider health service context, and 2) at the national, regional and municipal level, and do economic analyses.",[27],[254,255,256,257,258,259,260,261,262,263,264],"Implementation science","Decision-making processes","Hospital","Geriatric","Next of kin","Clinical ethics","Qualitative methods","Cluster randomized clinical trial","Complex intervention","Health services for the aged","End of life","2025-04-02",{"date":267,"type":32},"2025-04-06",{"date":269,"type":32},"2023-10-18",{"date":271,"type":21},"2026-12",{"name":273,"class":39},"University of Oslo",{"id":275,"slug":276,"hasResults":11,"nctId":277,"briefTitle":278,"officialTitle":279,"acronym":280,"eligibilityCriteria":281,"healthyVolunteers":11,"sex":17,"minAge":282,"maxAge":4,"enrollmentInfo":283,"targetDuration":4,"studyType":22,"phases":285,"briefSummary":286,"conditions":287,"keywords":293,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":301,"lastUpdatePostDateStruct":302,"startDateStruct":304,"completionDateStruct":306,"leadSponsor":308,"locationsCount":310},"100572291","improved-prescribing-for-older-nursing-home-patients-100572291","NCT06731361","Improved Prescribing for Older Nursing Home Patients","Improving Medication Prescription in the contExt of Advance Care Planning for paTients Receiving Long Term nUrSing Home Care","IMPETUS","Inclusion Criteria:\n\nNursing home patients:\n\n* Age 65years and above\n* Living at long term care wards in nursing homes\n* Living at a long term care ward for at least 4 weeks before start of the study\n\nExclusion Criteria:\n\n* Temporary nursing home patients (i.e. geriatric rehabilitation or end-of-life\u002Fhospice care)\n* Life expectancy \\\u003C 4 weeks\n* Life expectancy clearly \\> 1.5 - 2 years (i.e. patients with Huntingtons disease)","65 Years",{"count":284,"type":21},450,[24],"Research aim:\n\nTo investigate the effect of training health care professionals in medication assessments on the medication use of nursing home residents with a limited life expectancy (\\\u003C 1.5-2 years).\n\nThe core of the training is to tailor medication use to (palliative) treatment goals of nursing home residents.\n\nDesign:\n\nA cluster randomized controlled trial on long term care wards in nursing homes, with the nursing home care organisations as unit of randomisation. The investigators intent to include 6 organisations and 450 nursing home patients. The research starts in september and lasts 1 year and 3 months. Eligible patients are nursing home patients of 65 years and older with a limited life expectancy (\\\u003C 1.5-2 year) of long term care wards.\n\nIntervention:\n\nThe intervention includes a method in which healthcare professionals (medical practitioner, pharmacist and care worker) are trained to tailor medication to the (palliative) treatment goals of nursing home patients with a limited life expectancy. The training consists of 2 components: 1) medication assessment, and 2) advance care planning (ACP). In the intervention group, healthcare professionals receive the training in combination with supporting tools and educational materials, in the control group care continues as normal. The allocation ratio for control and intervention groups is 1:1. A process evaluation will take place simultaneously with the intervention study. Data collection takes place before the start of the intervention (T0), after 6 months (T1) and after 12 months (T2).\n\nOutcome measures:\n\nThe primary outcome measure is potential under- and over-treatment with medication. The secondary outcome measure is experienced involvement in decision-making (measured with a short questionnaire based on the revised PATD (patients' attitude towards deprescribing)). Tertiary outcome measures are: quality of life, deaths, falls, hospital admissions\u002Facute first aid referrals and pain.\n\nDiscussion:\n\nThe intervention is expected to result in a decrease in chronic and preventive medication prescriptions, an increase in medication for symptom treatment and more involvement (and satisfaction) of the nursing home resident in decision-making, without adverse effects.",[288,289,290,27,291,197,292],"Nursing Home Residents","Older People","Prescribing","Medication Reviews","Prescribing Practices",[294,295,296,297,298,299,300],"limited life expectancy","ReNeWAL criteria (adjusted STOPP\u002FSTART criteria)","decision making involvement","appropriate prescribing","Cluster randomised trial","Educational intervention","Prescribing practices","2024-12-09",{"date":303,"type":32},"2024-12-12",{"date":305,"type":32},"2024-09-10",{"date":307,"type":21},"2025-12-01",{"name":309,"class":39},"Amsterdam UMC, location VUmc",7,{"id":312,"slug":313,"hasResults":11,"nctId":314,"briefTitle":315,"officialTitle":316,"acronym":317,"eligibilityCriteria":318,"healthyVolunteers":11,"sex":17,"minAge":319,"maxAge":4,"enrollmentInfo":320,"targetDuration":4,"studyType":22,"phases":322,"briefSummary":323,"conditions":324,"keywords":326,"overallStatus":101,"whyStopped":4,"lastUpdateSubmitDate":332,"lastUpdatePostDateStruct":333,"startDateStruct":335,"completionDateStruct":337,"leadSponsor":339,"locationsCount":208},"100553117","home-based-nurse-intervention-in-the-care-of-high-risk-of-death-patients-after-discharge-from-geriatric-department-100553117","NCT06481917","Home-based Nurse Intervention in the Care of High Risk of Death Patients After Discharge From Geriatric Department","Feasibility and Effectiveness of a Specialized Home-based Nurse Intervention on the Completion of Advance Care Plans of Patients at High Risk of Death After Discharge From Acute Care Geriatric Departement","SAPHARI","Inclusion Criteria:\n\n* Patients aged 75 or over.\n* Affiliated to a social security scheme.\n* Hospitalized in an acute care geriatric department\n* Discharged from hospital to home or residential facilities for dependent elderly people\n* Targeted pathology or at least one incurable disease.\n* At high risk of death in the twelve months following discharge according to the DAMAGE prognostic score (high-risk score group). A high risk of death is defined by a DAMAGE score \\> 50%.\n* Rockwood Clinical frailty scale score greater than or equal to 7 at one month.\n\nExclusion Criteria:\n\n* Refusal to participate in the study expressed by the patient or his\u002Fher legal representative, if applicable.\n* Patients transferred to another Medicine-Surgery-Obstetrics department (only \"medicine or surgery\" in the elderly).\n* Patients transferred to follow-up care and rehabilitation, palliative care, or returning home in palliative care.\n* Patients who have already drawn up advance directives, chosen a trusted support person or discussed their end-of-life wishes with their doctor.\n* Patients with proven severe neuro-cognitive disorders (in the medical record with a Mini-Mental State Examination (MMSE) score below 10 or in the absence of knowledge of the degree of severity and\u002For a recent previous MMSE score taken in a stable period, the referring practitioner, a geriatrician with expertise in this field, will assess whether the patient is unfit to state his or her advance directives at the time of inclusion.","75 Years",{"count":321,"type":21},104,[24],"This study consists to evaluate the feasibility of a case-management intervention of Advance Care Plan (ACP) placement for elderly patients at high risk of death at twelve months discharged alive from acute geriatric medicine.\n\nFeasibility will include the following indicators: rate of patients included and randomized, rate of patients remaining in the study, ACP rates achieved at one month.",[325,27],"Health Services for the Aged",[327,328,329,330,331],"Elderly","Advance care plan","DAMAGE score","High risk of mortality","Discharge from acute care geriatric department","2024-07-01",{"date":334,"type":32},"2024-07-03",{"date":336,"type":21},"2024-10",{"date":338,"type":21},"2027-10",{"name":340,"class":39},"Lille Catholic University",{"id":342,"slug":343,"hasResults":11,"nctId":344,"briefTitle":345,"officialTitle":345,"acronym":346,"eligibilityCriteria":347,"healthyVolunteers":11,"sex":17,"minAge":74,"maxAge":4,"enrollmentInfo":348,"targetDuration":350,"studyType":165,"phases":4,"briefSummary":351,"conditions":352,"keywords":355,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":356,"lastUpdatePostDateStruct":357,"startDateStruct":359,"completionDateStruct":361,"leadSponsor":363,"locationsCount":40},"100543061","implementation-of-online-advance-care-planning-tool-for-hemato-oncological-patients-within-the-cancer-network-concord-100543061","NCT06350968","Implementation of Online Advance Care Planning Tool for (Hemato-)Oncological Patients Within the Cancer Network Concord","INDEED","Inclusion Criteria:\n\n* Cancer\n* Treated by hospital from the CONCORD-network\n\nExclusion Criteria:\n\n\\-",{"count":349,"type":21},30,"3 Years","The aim of this mixed-methods study is to describe both the implementation process and outcomes of the online module Advance Care Plan for (hemato-)oncology patients within the oncology-network CONCORD.\n\nThe main question is: How is implementation and assurance of the advance care plan in daily care for (hemato-)oncological patients within CONCORD achieved, so that early integration of advance care planning in oncological care takes place and patient preferences are discussed?\n\nHealthcare providers and patients are asked to use the module and share their experiences with it.",[353,27,354],"Oncology","Implementation",[27,353],"2024-04-03",{"date":358,"type":32},"2024-04-08",{"date":360,"type":32},"2023-10-01",{"date":362,"type":21},"2026-12-31",{"name":364,"class":39},"Erasmus Medical Center"]