[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"advanced-solid-tumour\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:advanced-solid-tumour":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,41,62,80],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":40},"100601519","phase-2-a-clinical-trial-of-lbl-024-combination-drug-in-patients-with-advanced-solid-tumourssubstudy-02btchcc-100601519",false,"NCT07111546","A Clinical Trial of LBL-024 Combination Drug in Patients With Advanced Solid Tumours[Substudy 02(BTC&HCC)]","An Open-label, Multicenter, Phase II Clinical Study to Evaluate the Efficacy and Safety of LBL-024 in Combination With Other Drugs for the Treatment of Patients With Advanced Solid Tumour[Substudy Number 02(BTC&HCC)]","Inclusion Criteria:\n\n1. Agree to follow the trial treatment regimen, visit schedule, laboratory test, and other requirements of the protocol, and voluntarily enroll in the study and sign the written informed consent.\n2. Age 18-75 years (inclusive of boundaries) at the time of signing informed consent form.\n3. The Eastern Cooperative Oncology Group's physical status scoring standard (ECOG) is 0\\~1.\n4. The expected survival time is at least 12 weeks.\n5. According to the evaluation of RECIST 1.1 standard, the subjects enrolled have at least one measurable lesion.\n6. There is adequate organ and bone marrow function,Conforms to laboratory test results.\n7. Males with fertility and females of childbearing age are willing to take effective contraceptive measures From the signing of the informed consent form to within 6 months after the last administration of the trial drug.\n\nExclusion Criteria:\n\n1. Participation in clinical studies of antineoplastic agents within 4 weeks before the first use of study drug,or Subject is expected to receive any other form of systemic or local anti-tumor therapy outside the protocol during the study.\n2. Use of immunomodulatory drugs within 2 weeks before the first use of study drug,Including but not limited to thymopeptide, interleukins, interferon, etc.\n3. Patients with active infection and requiring intravenous anti-infective therapy within 2 weeks before the first dose.\n4. Patients with clinically uncontrollable pleural effusion, pericardial effusion, ascites, and those requiring repeated drainage or medical intervention.\n5. The patient has a Medical history of immunodeficiency, including HIV antibody positive.\n6. Women during pregnancy or lactation.\n7. History of mental illness (interfering with understanding or giving informed consent), drug abuse, alcoholism or drug addiction.\n8. The investigator believes that the subject has other conditions that may affect compliance or are not suitable for participating in this study.","ALL","18 Years","75 Years",{"count":20,"type":21},140,"ESTIMATED","INTERVENTIONAL",[24],"PHASE2","An open-label, multicenter, phase II clinical study to evaluate the efficacy and safety of LBL-024 in combination with other drugs for the treatment of patients with advanced solid tumour.",[27],"Advanced Solid Tumour","RECRUITING","2026-05-22",{"date":31,"type":32},"2026-05-26","ACTUAL",{"date":34,"type":32},"2025-10-20",{"date":36,"type":21},"2027-12-26",{"name":38,"class":39},"Nanjing Leads Biolabs Co.,Ltd","INDUSTRY",8,{"id":42,"slug":43,"hasResults":11,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":4,"eligibilityCriteria":47,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":48,"targetDuration":4,"studyType":22,"phases":50,"briefSummary":51,"conditions":52,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":53,"lastUpdatePostDateStruct":54,"startDateStruct":56,"completionDateStruct":58,"leadSponsor":60,"locationsCount":61},"100618402","phase-2-a-phase-ii-clinical-study-of-lbl-024-combination-therapy-in-patients-with-advanced-solid-tumoursubstudy-03escc-100618402","NCT07331155","A Phase II Clinical Study of LBL-024 Combination Therapy in Patients With Advanced Solid Tumour[Substudy 03(ESCC)]","An Open-label, Multicenter, Phase II Clinical Study to Evaluate the Efficacy and Safety of LBL-024 in Combination With Other Drugs for the Treatment of Patients With Advanced Solid Tumour[Substudy Number 03(ESCC)]","Inclusion Criteria:\n\n1. Agree to follow the trial treatment regimen, visit schedule, laboratory test, and other requirements of the protocol, and voluntarily enroll in the study and sign the written informed consent.\n2. Age ≥ 18 years at the time of signing the informed consent.\n3. Eastern Cooperative Oncology Group (ECOG) performance status score of 0-1.\n4. The expected survival time is at least 12 weeks.\n5. According to the evaluation of RECIST 1.1 standard, the subjects enrolled have at least one measurable lesion.\n6. There is adequate organ and bone marrow function,Conforms to laboratory test results.\n7. Males with fertility and females of childbearing age are willing to take effective contraceptive measures From the signing of the informed consent form to within 6 months after the last administration of the trial drug (including abstinence, intrauterine device, various hormonal contraception, correct use of contraception Sets，etc）; Women of childbearing age include pre-menopausal women and women within 2 years after menopause. Women of childbearing age must have a negative pregnancy test within 7 days before the first trial drug is administered.\n\nExclusion Criteria:\n\n1. Participation in clinical studies of antineoplastic agents within 4 weeks before the first use of study drug,or is expected to receive any other form of systemic or local anti-tumor therapy outside the protocol during the study.\n2. Use of immunomodulatory drugs within 2 weeks before the first use of study drug,Including but not limited to thymopeptide, interleukins, interferon, etc.\n3. Patients with active, or who have had and have the possibility of recurrence of autoimmune diseases.\n4. Patients with clinically uncontrollable pleural effusion, pericardial effusion, ascites, and those requiring repeated drainage or medical intervention.\n5. The patient has a Medical history of immunodeficiency, including HIV antibody positive.\n6. Active hepatitis B or active hepatitis C.\n7. Women during pregnancy or lactation.\n8. The investigator believes that the subject has other conditions that may affect compliance or are not suitable for participating in this study.",{"count":49,"type":21},110,[24],"An Open-label, Multicenter, Phase II Clinical Study to Evaluate the Efficacy and Safety of LBL-024 in Combination With Other Drugs for the Treatment of Patients With Advanced Solid Tumour.",[27],"2026-05-15",{"date":55,"type":32},"2026-05-18",{"date":57,"type":32},"2026-02-26",{"date":59,"type":21},"2028-12-26",{"name":38,"class":39},7,{"id":63,"slug":64,"hasResults":11,"nctId":65,"briefTitle":66,"officialTitle":67,"acronym":4,"eligibilityCriteria":68,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":69,"targetDuration":4,"studyType":22,"phases":71,"briefSummary":25,"conditions":72,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":53,"lastUpdatePostDateStruct":73,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":79},"100576311","phase-2-a-clinical-trial-of-lbl-024-combination-drug-in-patients-with-advanced-solid-tumourssubstudy-01nsclc-100576311","NCT06783647","A Clinical Trial of LBL-024 Combination Drug in Patients With Advanced Solid Tumours[Substudy 01(NSCLC)]","An Open-label, Multicenter, Phase II Clinical Study to Evaluate the Efficacy and Safety of LBL-024 in Combination With Other Drugs for the Treatment of Patients With Advanced Solid Tumour[Substudy Number 01(NSCLC)]","Inclusion Criteria:\n\n1. Agree to follow the trial treatment regimen, visit schedule, laboratory test, and other requirements of the protocol, and voluntarily enroll in the study and sign the written informed consent.\n2. Age 18-75 years (inclusive of boundaries) at the time of signing informed consent form.\n3. The Eastern Cooperative Oncology Group's physical status scoring standard (ECOG) is 0\\~1.\n4. The expected survival time is at least 12 weeks.\n5. According to the evaluation of RECIST 1.1 standard, the subjects enrolled have at least one measurable lesion.\n6. There is adequate organ and bone marrow function,Conforms to laboratory test results.\n7. Males with fertility and females of childbearing age are willing to take effective contraceptive measures From the signing of the informed consent form to within 6 months after the last administration of the trial drug (including abstinence, intrauterine device, various hormonal contraception, correct use of contraception Sets，etc）; Women of childbearing age include pre-menopausal women and women within 2 years after menopause. Women of childbearing age must have a negative pregnancy test within 7 days before the first trial drug is administered.\n\nExclusion Criteria:\n\n1. Participation in clinical studies of antineoplastic agents within 4 weeks before the first use of study drug,or Subject is expected to receive any other form of systemic or local anti-tumor therapy outside the protocol during the study.\n2. Use of immunomodulatory drugs within 2 weeks before the first use of study drug,Including but not limited to thymopeptide, interleukins, interferon, etc.\n3. Patients with active infection.\n4. Patients with clinically uncontrollable pleural effusion, pericardial effusion, ascites, and those requiring repeated drainage or medical intervention.\n5. The patient has a Medical history of immunodeficiency, including HIV antibody positive.\n6. Active hepatitis B or active hepatitis C.\n7. Women during pregnancy or lactation.\n8. History of mental illness (interfering with understanding or giving informed consent), drug abuse, alcoholism or drug addiction.\n9. The investigator believes that the subject has other conditions that may affect compliance or are not suitable for participating in this study.",{"count":70,"type":21},230,[24],[27],{"date":55,"type":32},{"date":75,"type":32},"2025-06-11",{"date":77,"type":21},"2026-12-24",{"name":38,"class":39},24,{"id":81,"slug":82,"hasResults":11,"nctId":83,"briefTitle":84,"officialTitle":85,"acronym":4,"eligibilityCriteria":86,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":87,"targetDuration":4,"studyType":22,"phases":88,"briefSummary":51,"conditions":89,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":61},"100622958","phase-2-a-phase-ii-clinical-trial-of-lbl-024-combination-drug-in-patients-with-advanced-solid-tumoursubstudy-04-100622958","NCT07390383","A Phase II Clinical Trial of LBL-024 Combination Drug in Patients With Advanced Solid Tumour[Substudy 04]","An Open-label, Multicenter, Phase II Clinical Study to Evaluate the Efficacy and Safety of LBL-024 in Combination With Other Drugs for the Treatment of Patients With Advanced Solid Tumour[Substudy Number 04]","Inclusion Criteria:\n\n1. Agree to follow the trial treatment regimen, visit schedule, laboratory test, and other requirements of the protocol, and voluntarily enroll in the study and sign the written informed consent.\n2. Age ≥ 18 years at the time of signing the informed consent.\n3. Eastern Cooperative Oncology Group (ECOG) performance status score of 0-1.\n4. The expected survival time is at least 12 weeks.\n5. According to the evaluation of RECIST 1.1 standard, the subjects enrolled have at least one measurable lesion.\n6. Patients with histologically confirmed unresectable locally advanced or metastatic gastric\u002Fgastroesophageal junction (G\u002FGEJ) adenocarcinoma.\n7. There is adequate organ and bone marrow function,Conforms to laboratory test results.\n8. Males with fertility and females of childbearing age are willing to take effective contraceptive measures From the signing of the informed consent form to within 6 months after the last administration of the trial drug (including abstinence, intrauterine device, various hormonal contraception, correct use of contraception Sets，etc）; Women of childbearing age include pre-menopausal women and women within 2 years after menopause. Women of childbearing age must have a negative pregnancy test within 7 days before the first trial drug is administered.\n\nExclusion Criteria:\n\n1. Participation in clinical studies of antineoplastic agents within 4 weeks before the first use of study drug,or is expected to receive any other form of systemic anti-tumor therapy outside the protocol during the study.\n2. Use of immunomodulatory drugs within 2 weeks before the first use of study drug,Including but not limited to thymopeptide, interleukins, interferon, etc.\n3. Patients with active, or who have had and have the possibility of recurrence of autoimmune diseases.\n4. Patients with clinically uncontrollable pleural effusion, pericardial effusion, ascites, and those requiring repeated drainage or medical intervention.\n5. The patient has a Medical history of immunodeficiency, including HIV antibody positive.\n6. Active hepatitis B or active hepatitis C.\n7. Women during pregnancy or lactation.\n8. The investigator believes that the subject has other conditions that may affect compliance or are not suitable for participating in this study.",{"count":49,"type":21},[24],[27],"2026-05-12",{"date":92,"type":32},"2026-05-13",{"date":94,"type":32},"2026-04-13",{"date":96,"type":21},"2028-05-30",{"name":38,"class":39}]