[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"aedes-borne-diseases\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:aedes-borne-diseases":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":5},"100591516","implementation-and-evaluation-of-vector-control-methods-in-kinshasa-the-case-of-aedes-100591516",false,"NCT06981442","Implementation and Evaluation of Vector Control Methods in Kinshasa: The Case of Aedes","Implementation and Evaluation of Vector Control Methods in Kinshasa: The Case of Aedes, Vectors of Arboviruses.","At household level:\n\nInclusion Criteria:\n\n* Belong to a household in one of the 4 health areas selected as study arms\n* From 18 years of age to consent for household enrollment and participation in the serosurvey\n* Consenting\n\nExclusion Criteria:\n\n* Not belong to a household in one of the 4 health areas selected as study arms\n* Under 18 years of age\n* Non-consenting\n\nAt health facility level:\n\nInclusion Criteria:\n\n* From 18 years of age\n* Resident of the health zone of Mont Ngafula 1\n* Consenting\n\nExclusion Criteria:\n\n* Under 18 years of age\n* Not resident in the health zone of Mont Ngafula 1\n* Seriously ill and hospitalized, requiring transfusion, presence of blood clotting disorders, allergies resulting from injections, adverse events associated with previous blood sampling, pregnancy\n* Non-consenting",true,"ALL","18 Years",{"count":20,"type":21},2050,"ESTIMATED","INTERVENTIONAL",[24],"NA","Arboviral diseases are viral diseases transmitted by mosquitoes of the Aedes genus and are constantly spreading throughout the world, constituting a significant threat to public health.\n\nIn Africa, there is very little data on the epidemiological situation of Aedes-borne diseases and programs for monitoring these diseases are very limited. In the Democratic Republic of the Congo (DRC), several epidemics of yellow fever, dengue fever, chikungunya and Zika cases have been reported. In particular, in Kinshasa, the dengue and chikungunya viruses have previously been detected in patients with undifferentiated fevers and several studies have shown entomological transmission indices above the criteria and standards of the World Health Organization (WHO).\n\nThe aim of our study is to implement and evaluate different strategies to control Aedes mosquitoes at different stages of their life cycle in the city of Kinshasa.\n\nIn particular, a before-and-after interventional study will be piloted and tested in the health zone of Kinshasa, with the aim of providing preliminary evidence of the impact of vector control tools.\n\nInterventions will be implemented in 400 households for each arm for 12 months. Before, after and during the interventions, entomological surveys will be conducted in 160 households in each arm to define the density of the vectors. Mosquitoes will be tested for the possible presence of arbovirus RNA (dengue, chikungunya, Zika, yellow fever). During the pre-intervention period, a serological survey for the same diseases transmitted by the Aedes mosquito will be conducted on a sample of 450 people included in two health centers of reference for the health zone of Mont Ngafula 1. A questionnaire will also be administered before and after the intervention implementation to assess the community's knowledge, attitudes and practices towards Aedes mosquito vector control and Aedes-borne diseases.\n\nThe integration of the data collected within the scope of this study will provide an assessment of the feasibility and impact of the tested methods on entomological indicators, as well as determining the exposure and knowledge of Aedes-borne diseases in the Mont Ngafula 1 area.",[27],"Aedes-borne Diseases",[29,30,31],"Vector control","Aedes mosquitoes","Democratic Republic of the Congo","RECRUITING","2025-05-12",{"date":35,"type":36},"2025-05-20","ACTUAL",{"date":38,"type":36},"2025-03-26",{"date":40,"type":21},"2026-12-31",{"name":42,"class":43},"Institute of Tropical Medicine, Belgium","OTHER"]