[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"aesthetic-outcomes\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:aesthetic-outcomes":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,49],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":31,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":48},"100617386","lateral-crural-steal-with-columellar-strut-graft-in-primary-open-rhinoplasty-100617386",false,"NCT07317947","Lateral Crural Steal With Columellar Strut Graft in Primary Open Rhinoplasty","The Effect of Lateral Crural Steal With Columellar Strut Graft on Nasal Tip Projection and Rotation in Primary Open Rhinoplasty","LCS\u002FCS","Inclusion Criteria:\n\n* Patients seeking primary rhinoplasty for aesthetic and\u002For functional indications.\n* Presence of inadequate nasal tip projection and\u002For rotation suitable for correction using lateral crural steal with columellar strut graft.\n* Ability to provide written informed consent and comply with follow-up visits.\n\nExclusion Criteria:\n\n* History of prior nasal surgery.\n* History of severe nasal trauma, altering cartilage architecture.\n* Significant functional nasal obstruction requiring complex external nasal valve reconstruction.\n* Patients with excessively wide alar base requiring alar base reduction involving vestibular sill excision (to prevent confounding on projection\u002Frotation).\n* Patients with facial skeletal or developmental abnormalities e.g. maxillary hypoplasia, maxillary prognathism, dentofacial deformities.\n* Patients with psychiatric illness or Body Dysmorphic Disorder.\n* Significant medical comorbidities contraindicating elective surgery or general anesthesia.\n* Inability to provide informed consent or comply with follow-up.","ALL","18 Years","60 Years",{"count":21,"type":22},22,"ESTIMATED","INTERVENTIONAL",[25],"NA","The goal of this clinical trial is to assess the effect of Lateral crural steal with Columellar strut graft done in Primary Open Rhinoplasty and its long-term sustainability on nasal tip projection and nasal tip rotation.",[28,29,30],"Rhinoplasty","Nasal Surgery","Aesthetic Outcomes",[28,32,33,34,35],"Lateral crural steal","Columellar strut","Rhinobase","Rhinoplasty Outcome Evaluation","RECRUITING","2026-01-08",{"date":39,"type":40},"2026-01-09","ACTUAL",{"date":42,"type":40},"2026-01-05",{"date":44,"type":22},"2027-02",{"name":46,"class":47},"Kafrelsheikh University","OTHER",1,{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":55,"eligibilityCriteria":56,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":57,"targetDuration":4,"studyType":23,"phases":59,"briefSummary":60,"conditions":61,"keywords":65,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":72,"completionDateStruct":73,"leadSponsor":75,"locationsCount":4},"100585032","efficacy-of-a-gel-containing-polynucleotides-and-hyaluronic-acid-in-supraosseous-periodontal-defects-treated-with-the-single-flap-approach-100585032","NCT06897085","Efficacy of a Gel Containing Polynucleotides and Hyaluronic Acid in Supraosseous Periodontal Defects Treated with the Single Flap Approach","Efficacy of a Gel Containing Polynucleotides and Hyaluronic Acid in the Treatment of Periodontal Supraosseous Defects with the Single Flap Approach: a Randomized Controlled Trial","SFA-SD","INCLUSION CRITERIA Patient-specific\n\n* age≥ 18 years;\n* diagnosis of Stage III or IV periodontitis22;\n* good physical status (ASA1 and ASA2 according to Physical Status Classification System);\n* systemic and local conditions compatible with periodontal surgical procedures;\n* patient willing and fully capable to comply with the study protocol.\n\nSite-specific\n\n* defect located in an incisor, canine or premolar region which becomes exposed during spontaneous smiling;\n* defect with an intrabony component (as assessed on periapical radiograph and confirmed intra-surgically) ≤ 2 mm;\n* defect with a radiographic CEJ-BC≥ 4 mm; d) residual (following step I-II of treatment) PD≥6 mm at both interproximal aspects facing the SD.\n\nEXCLUSION CRITERIA Patient-specific\n\n* poorly controlled diabetes (HbA1C ≥ 7%);\n* history of radiation therapy in the head and neck area;\n* history of chemotherapy;\n* systemic disease or conditions with a documented effect on bone metabolism and\u002For periodontal status\u002Fhealing;\n* past (within 6 months prior to enrollment in the study) or current treatment with any medication with a documented effect on bone metabolism and\u002For periodontal status\u002Fhealing;\n* physical or mental handicap that can interfere with adherence to the study procedures and adequate hygienic compliance;\n* documented allergy to dental materials involved in the experimental protocol;\n* pregnancy or lactation;\n* history of drug or alcohol abuse.\n\nMoreover, participants will be immediately excluded from the study:\n\n* upon request to withdraw from further participation;\n* development of acute dental\u002Fperiodontal or oral conditions requiring treatment;\n* development of conditions conflicting with the exclusion criteria listed above\n* failure to comply with study instructions\u002Frequirements.\n\nSite-specific\n\n* presence of untreated endodontic lesions or inadequate endodontic treatment of teeth facing the SD;\n* presence of orthodontic appliances;\n* local conditions preventing proper plaque control at experimental sites;\n* grade III mobility.",{"count":58,"type":22},70,[25],"Treatment of supraosseous defects (SD) may be challenging due to their limited regenerative potential. When located in aesthetic areas, treatment may result in a gingival recession increase with consequent patients' concerns in terms of aesthetic or tooth sensibility. In the present study, a minimally-invasive surgical procedure (namely, the Single Flap Approach, SFA) will be combined with the application of a viscoelastic gel containing polynucleotides and hyaluronic acid that was reported to positively modulate periodontal wound healing. The outcomes, evaluated 6 months after treatment, will be compared to those obtained with SFA alone. The evaluated outcomes will be either clinical (evaluation of clinical parameters such as gingival recession, residual probing depth, clinical attachment gain) or related to patient's perception (such as evaluation of the aesthetic or tooth sensibility).",[62,63,64,30],"Periodontitis","Gingival Recession, Localized","Aesthetic Perception",[66,67],"minimally invasive","single flap approach","NOT_YET_RECRUITING","2025-03-26",{"date":71,"type":40},"2025-04-01",{"date":71,"type":22},{"date":74,"type":22},"2026-12-30",{"name":76,"class":47},"Azienda Unità Sanitaria Locale (A.U.S.L.) Ferrara, Italy"]