[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"affect-mental-function\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:affect-mental-function":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,60],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":25,"briefSummary":27,"conditions":28,"keywords":35,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":48,"lastUpdatePostDateStruct":49,"startDateStruct":52,"completionDateStruct":54,"leadSponsor":56,"locationsCount":59},"100635242","etascan-project-etas-project-2-100635242",false,"NCT07550140","ETASCAN Project: ETAS Project 2","The Impact of Chronic Consumption of ETAS® for 12 Weeks on Cognitive, Affective, and Neural Outcomes: A Randomised Parallel Group Placebo-controlled Study","ETASCAN","Inclusion Criteria:\n\n* Aging between 60-80 years old\n* Having normal vision and hearing\n* Having a body mass index between 18.5 and 30\n* Having mild to moderate subjective cognitive complaints\n\nExclusion Criteria:\n\n* Smoking\n* Having food allergies\n* Following restrictive and\u002For unbalanced diets (Appendix 6: Are you vegetarian or vegan? Yes \u002F No; Are you currently on a weight-reducing or other special diet? Yes\u002FNo If 'Yes', please give details.)\n* Being diagnosed with any psychiatric or neurologic conditions (e.g. schizophrenia, depression, dementia) including eating disorders\n* Being diagnosed with any cardiometabolic diseases (including type II diabetes and cardiovascular disease), or hypertension or thrombosis related disorders or suffer from thyroid disease\n* Currently taking anticoagulants, antiplatelet medication, antidepressants, proton-pump inhibitors\n* Currently consuming prebiotic or probiotic supplements\n* Continuous antibiotic use for \\> 3 days within 1 month prior to enrolment\n* Continuous use of weight-loss drug for \\> 1 month before screening\n* Having a significant gastrointestinal (GI) condition affecting absorption including (but not limited to) inflammatory bowel disease; total colectomy or bariatric surgery; irritable bowel disease; end stage renal disease; active cancer, or treatment for any cancer, in last 3 years\n* History of claustrophobia\n* Fitted with a pacemaker or artificial heart valve\n* Have active implants, such as cochlear, ocular, or penile implant\n* Experience of metal fragments e.g. shrapnel in your eyes or any other part of your body\n* Drug infusion pump installed\n* Have any surgically implanted metal in any part of your body, other than dental fillings and crowns (e.g. joint replacement or bone re-construction)\n* Have had any surgery that might have involved metal implants\n* Current or historical experience of epilepsy\n* Have stimulators for nerves, brain or bone installed\n* Have an intrauterine contraceptive device installed (IUD)\n* Wear transdermal patches containing metal\n* Wear a filling, crown, dental post (entirely within the tooth) associated with root canal treatment, retainer, bridge or braces\n* For scanning, would need to remove coloured contact lenses, nail polish and makeup.\n* Hearing aid wearer\n* Body piercings that you cannot or will not remove for the scanning session\n* Have tattoos or permanent makeup",true,"ALL","60 Years","80 Years",{"count":22,"type":23},60,"ESTIMATED","INTERVENTIONAL",[26],"NA","This study aims to investigate the chronic effects of ETAS® on cognitive, affective and neural outcomes in healthy adults aged 60-80 years with mild to moderate subjective cognitive complaints.",[29,30,31,32,33,34],"Cognition","Affect (Mental Function)","Sleep","MRI","fMRI","Magnetic Resonance Spectroscopy",[36,37,38,39,40,41,42,43,44,45,46],"grey matter","brain structure","brain function","neurochemistry","executive function","language","ETAS®","depression","anxiety","sleep","gut microbiome","RECRUITING","2026-04-17",{"date":50,"type":51},"2026-04-24","ACTUAL",{"date":53,"type":23},"2026-05-05",{"date":55,"type":23},"2027-12-31",{"name":57,"class":58},"University of Reading","OTHER",1,{"id":61,"slug":62,"hasResults":11,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":4,"eligibilityCriteria":66,"healthyVolunteers":17,"sex":18,"minAge":67,"maxAge":4,"enrollmentInfo":68,"targetDuration":4,"studyType":24,"phases":70,"briefSummary":71,"conditions":72,"keywords":76,"overallStatus":84,"whyStopped":4,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":59},"100591388","testing-the-efficacy-of-the-syd-app-on-improving-quality-of-life-and-mental-health-among-university-students-in-the-kingdom-of-saudi-arabia-100591388","NCT06979778","Testing the Efficacy of the \"Syd\" App on Improving Quality of Life and Mental Health Among University Students in the Kingdom of Saudi Arabia","A Randomized Controlled Trial to Assess the Efficacy of the \"Syd\" App on Improving Quality of Life and Mental Health Among University Students in the Kingdom of Saudi Arabia","Inclusion Criteria:\n\n* Age ≥ 18 years.\n* Enrolled as a full-time medical student at the Alfaisal university.\n* Owning a smartphone (iOS or Android) compatible with the \"syd\" app.\n* Willing to provide informed consent and comply with study procedures\n\nExclusion Criteria:\n\n* Known severe psychiatric or cognitive conditions that impede app usage\n* Inability to provide informed consent","18 Years",{"count":69,"type":23},600,[26],"The goal of this clinical trial is to learn if using the \"See Yourself Differently\" (syd) app can help improve quality of life and mental health for university students in Saudi Arabia. The study also aims to see if the app can help lower anxiety and stress, and increase positive feelings while decreasing negative feelings.\n\nThe main questions it aims to answer are:\n\n1. Does the \"syd\" app improve the quality of life for university students?\n2. Does the \"syd\" app help lower anxiety and stress in university students\n3. Does the \"syd\" app help increase positive feelings and decrease negative feelings in university students?\n\nResearchers will compare students who use the \"syd\" app to see if it works.\n\nParticipants will:\n\n1. Use the \"syd\" app for 3 months.\n2. Complete surveys about their quality of life, anxiety, stress, and feelings.",[73,74,75,30],"Quality of Life (QOL)","Anxiety","Stress",[77,78,79,80,81,82,83],"syd","QoL","See Yourself Differently","Quality of Life","mHealth","App","RCT","NOT_YET_RECRUITING","2025-05-20",{"date":87,"type":51},"2025-05-23",{"date":89,"type":23},"2025-05",{"date":91,"type":23},"2025-08",{"name":93,"class":94},"iamYiam Limited","INDUSTRY"]