[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"after-cardiac-surgery\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:after-cardiac-surgery":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":5},"100599576","evaluation-of-the-efficacy-of-rhbnp-in-patients-with-diuretic-resistance-after-cardiac-surgery-100599576",false,"NCT07086287","Evaluation of the Efficacy of rhBNP in Patients With Diuretic Resistance After Cardiac Surgery","Evaluation of the Efficacy of Recombinant Human Brain Natriuretic Peptide in Patients With Diuretic Resistance After Cardiac Surgery: a Prospective Single-center Single-blind Randomized Controlled Study","rhBNP","Inclusion Criteria:\n\n* (1) Adult patients after cardiac surgery (age ≥ 18 years) (2) Fluid overload (3) Diuretic resistance Definition: Daily intravenous use of furosemide at a dose ≥ 80mg or equivalent doses of other diuretics, yet still unable to achieve an adequate urine output of 0.5\\~1.0mL\u002Fkg\u002Fh. Conversion formula for different loop diuretics: Oral furosemide 80mg = Intravenous furosemide 40mg = Oral\u002FIntravenous torsemide 20mg = Oral\u002FIntravenous bumetanide 1mg (4) Willing to participate in the trial and sign the informed consent form.\n\nExclusion Criteria:\n\n* (1) Preoperative CKD patients undergo regular dialysis treatment; (2) Postoperative use of CRRT; (3) Drug allergies involved in this study; (4) Those with corrected systolic blood pressure still \\\u003C 90 mmHg after vasopressor use.","ALL","18 Years",{"count":20,"type":21},120,"ESTIMATED","INTERVENTIONAL",[24],"NA","evaluation of the efficacy of recombinant human brain natriuretic peptide in patients with diuretic resistance after cardiac surgery: a prospective single-center single-blind randomized controlled study",[27,28],"After Cardiac Surgery","Diuretic Resistance",[30,31,32,33],"recombinant human brain natriuretic peptide","diuretic resistance","after cardiac surgery","the incidence of renal replacement therapy","NOT_YET_RECRUITING","2025-07-18",{"date":37,"type":38},"2025-07-25","ACTUAL",{"date":40,"type":21},"2025-08-01",{"date":42,"type":21},"2028-06-30",{"name":44,"class":45},"The First Affiliated Hospital of Anhui Medical University","OTHER"]