[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"age-related-cataracts\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:age-related-cataracts":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,42,70,92],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100502425","intraindividual-comparison-of-emo-iols-100502425",false,"NCT05822089","Intraindividual Comparison of EMO IOLs","Comparison of Visual Outcomes of Enhanced Monofocal Intraocular Lenses","EMO","Inclusion Criteria:\n\n* Bilateral age-related cataract planned for phacoemulsification extraction and posterior IOL implantation\n* Age 50 to 100\n* Visual potential in both eyes of 20\u002F25 or better as determined by investigators estimation\n* Normal findings in medical history and physical examination unless the investigator considers an abnormality to be clinically irrelevant\n* Irregular Astigmatism (Acrysof IQ Vivity IOL, IC-8 Apthera IOL)\n* postoperativ binocular best corrected distance visual acuity (BCVA) ≥ 1.0 decimal (Arm ten (X))\n* Standard cataract surgery with bilateral implantation of a monofocal IOL (Vivinex XC1 or Vivinex XY1) (Arm ten (X))\n\nExclusion Criteria:\n\n* Preceding intraocular surgery or ocular trauma\n* Relevant other ophthalmic diseases that particularly effects the zonular apparatus (such as severe pseudoexfoliation syndrome, preceding cryocoagulation, trauma)\n* Pupil diameter \\\u003C 2.0 mm (photopic)\n* Laser treatment\n* Uncontrolled systemic or ocular disease\n* Pregnancy\u002FNursing\n* childbearing ability","ALL","50 Years","100 Years",{"count":21,"type":22},461,"ESTIMATED","INTERVENTIONAL",[25],"NA","The investigational devices are approved intraocular lenses (IOLs) intended to be implanted after phacoemulsification in individuals suffering from age-related cataract with the need of cataract surgery. Cataract surgery with precedent bilateral randomized IOL implantation will be performed in subjects who have signed an informed consent form. Postoperative examinations will be implemented in accordance with the approved investigational plan.",[28],"Age Related Cataracts","RECRUITING","2025-11-27",{"date":32,"type":33},"2025-12-05","ACTUAL",{"date":35,"type":33},"2021-12-13",{"date":37,"type":22},"2026-12-31",{"name":39,"class":40},"Medical University of Vienna","OTHER",1,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":4,"eligibilityCriteria":48,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":49,"targetDuration":4,"studyType":23,"phases":51,"briefSummary":52,"conditions":53,"keywords":54,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":63,"completionDateStruct":65,"leadSponsor":67,"locationsCount":69},"100593437","visual-performance-of-clareon-panoptix-vs-a-comparable-multifocal-intraocular-lens-100593437","NCT07006428","Visual Performance of Clareon PanOptix vs. a Comparable Multifocal Intraocular Lens","Visual Performance Differences Between Clareon PanOptix and a Comparable Multifocal Intraocular Lens","Inclusion Criteria:\n\nStage 1: IIT Pilot\n\n* Willing and able to understand and sign informed consent.\n* Adult patients previously diagnosed with age-related cataracts bilaterally.\n* Previous bilateral age-related cataract removal and with bilateral implantation of the Clareon PanOptix\u002F Clareon PanOptix Toric (T3-T4) or Comparable Multifocal Intraocular Lens (equivalent to T3-T4) closest to 2.5-5-months after implantation and \\>2 weeks post YAG (if done) that were targeted for emmetropia.\n* Best monocular corrected distance visual acuity was expected to be 0.1 logMAR (Snellen 20\u002F25) or better in both eyes pre-operatively as determined by surgeon.\n* Normal ocular findings aside from cataract.\n\nStage 2: Comparison\n\n* Willing and able to understand and sign informed consent.\n* Adult patient diagnosed with age-related cataracts bilaterally.\n* Planned bilateral cataract removal by femtosecond laser-assisted phacoemulsification with bilateral implantation of the Clareon PanOptix\u002FClareon PanOptix Toric (T3-T4) or Comparable Multifocal Intraocular Lens (equivalent to T3-T4).\n* Best monocular corrected distance visual acuity expected to be 0.1 logMAR (Snellen 20\u002F25) or better in both eyes postoperatively as determined by surgeon.\n* Residual astigmatism expected to be ≤ 0.50 diopters in both eyes postoperatively as determined by surgeon (after using either toric IOL or arcuate incision with laser).\n* Normal ocular findings aside from cataract.\n\nExclusion Criteria:\n\nStage 1: IIT Pilot\n\n* Corneal pathology, irregular astigmatism, preexisting macular disease and other retinal degenerative diseases, diabetic retinopathy that is expected to cause future vision loss, glaucoma, severe dry eye disease, nystagmus, strabismus, zonular laxity or dehiscence, pseudoexfoliation.\n* Previous history of any ocular surgery including corneal refractive surgery.\n* Participation in another clinical study that could interfere with the results.\n* Patients with monovision correction.\n* Any active ocular infection or inflammation.\n\nStage 2: Comparison\n\n* Corneal pathology, irregular astigmatism, preexisting macular disease and other retinal degenerative\n* diseases that is expected to cause future vision loss, glaucoma, severe dry eye disease, nystagmus, strabismus, zonular laxity or dehiscence, pseudoexfoliation.\n* Previous history of any ocular surgery including corneal refractive surgery.\n* Participants desiring monovision.\n* History of amblyopia or monofixation syndrome with poor stereoscopic vision.\n* Total corneal HOA greater than 0.6um, coma less than 0.3um at 4mm-5mm scan depending on pre- op photopic topography.\n* Any planned simultaneous\u002Fcombined procedures at time of cataract surgery (e.g. MIGs).\n* Participation in another clinical study that could interfere with the results.\n* Any active ocular infection or inflammation.",{"count":50,"type":22},290,[25],"This is a two-part, multi-center, investigator-initiated clinical study comparing visual outcomes and patient satisfaction in subjects receiving bilateral implantation of either the Clareon PanOptix intraocular lens (IOL) or a comparable multifocal IOL. The study includes a retrospective\u002Fprospective pilot phase and a prospective, randomized comparison phase.",[28],[55,56,57,58,59],"Clareon PanOptix","Multifocal IOL","Cataract Surgery","Visual Acuity","Intraocular Lens","2025-05-28",{"date":62,"type":33},"2025-06-05",{"date":64,"type":33},"2025-05-07",{"date":66,"type":22},"2025-11",{"name":68,"class":40},"Argus Research Center, Inc.",3,{"id":71,"slug":72,"hasResults":11,"nctId":73,"briefTitle":74,"officialTitle":74,"acronym":4,"eligibilityCriteria":75,"healthyVolunteers":11,"sex":17,"minAge":76,"maxAge":77,"enrollmentInfo":78,"targetDuration":4,"studyType":23,"phases":80,"briefSummary":81,"conditions":82,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":41},"100347446","rotation-of-hydrophobic-acrylic-lenses---rayner-ra0800c--alcon-clareon--hoya-nanex--hoya-vivinex-xy1-em--rayone-emv-toric--podeye-toric-100347446","NCT03803852","Rotation of Hydrophobic Acrylic Lenses - Rayner RA0800C & Alcon Clareon & Hoya Nanex & Hoya Vivinex XY1-EM & RayOne EMV Toric & PODEYE Toric","Inclusion Criteria:\n\n* Uni- or bilateral age-related cataract necessitating phacoemulsification extraction and posterior IOL implantation\n* Age: 45 to 95\n* Need for spherical IOL correction between 10.00 and 30.00 D\n* Need for spherical IOL correction between +6.00 and +30.00 D (Alcon Clareon toric group)\n* Need for spherical IOL correction between +10.00 and +25.00 D (Rayner RayOne EMV toric group)\n* Preoperative pupil dilation in mydriasis ≥ 7.0 mm (Hoya, Rayner groups)\n* Astigmatism of at least 1.0 Diopters (Alcon Clareon toric and Rayner RayOne EMV toric groups and PODEYE Toric)\n* Pupil dilation \\>5.5mm (Alcon Clareon toric Rayner RayOne EMV toric group)\n\nExclusion Criteria:\n\n* Preceding ocular surgery or trauma\n\n  * Recurrent intraocular inflammation of unknown etiology\n  * Uncontrolled glaucoma\n  * Uncontrolled systemic or ocular disease\n  * Blind fellow eye\n  * Microphthalmus\n  * Corneal abnormality (Corneal scaring)\n  * History of uveitis\u002Firitis\n  * Iris neovascularization\n  * Proliferative diabetic retinopathy\n  * Pregnancy\n  * Lactation\n  * Females of childbearing age will be asked if pregnancy is possible","45 Years","95 Years",{"count":79,"type":22},750,[25],"The investigational devices are approved intraocular lenses (IOL) intended to be implanted after phacoemulsification in individuals suffering from age-related cataract with the need of cataract surgery. Within the study, three different IOLs will be investigated and separately evaluated. Cataract surgery with IOL implantation will be performed in subjects who have signed an informed consent form. Postoperative examinations will be postoperative refraction, visual acuity, slitlamp examination, and rotation of the IOL within 1 hour, 1 week, 1 month and 4-7 months.\n\nIn the Alcon Clareon toric, RayOne EMV toric and PODEYE Toric group, patients receive a toric IOL according to their preoperative astigmatism",[28,83],"Astigmatism","2025-05-08",{"date":86,"type":33},"2025-05-14",{"date":88,"type":33},"2019-01-21",{"date":90,"type":22},"2028-01",{"name":39,"class":40},{"id":93,"slug":94,"hasResults":11,"nctId":95,"briefTitle":96,"officialTitle":97,"acronym":4,"eligibilityCriteria":98,"healthyVolunteers":11,"sex":17,"minAge":99,"maxAge":19,"enrollmentInfo":100,"targetDuration":4,"studyType":23,"phases":102,"briefSummary":103,"conditions":104,"keywords":106,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":112,"lastUpdatePostDateStruct":113,"startDateStruct":115,"completionDateStruct":117,"leadSponsor":119,"locationsCount":41},"100520206","outcome-of-two-surgical-methods-for-iolimplantation-in-eyes-with-pseudoexfoliation-syndrome-100520206","NCT06053554","Outcome of Two Surgical Methods for IOLImplantation in Eyes With Pseudoexfoliation Syndrome","Outcome of Two Surgical Methods for IOLImplantation in Eyes With Pseudoexfoliation Syndrome: Lens in the Bag-technique Versus Lens in the Ciliary Sulcus With Optic Capture Technique","Inclusion Criteria:\n\n* Age 60 - 100\n* Necessity for bilateral cataract surgery with pseudoexfoliation syndrome\n* willing to give informed consent and follow-up the duration of study\n\nExclusion Criteria:\n\n* Endstage glaucoma\n* Christalline lens sub\u002F luxation\n* active inflammatory diseases of the eye","60 Years",{"count":101,"type":22},120,[25],"The aim of this study is to compare the surgical outcomes of the two IOL implantation methods for eyes with cataract and PEX in a single-center and with highly experienced surgeons. The goal is to acquire relevant information regarding these two IOL implantation techniques, which will help surgeons to decide which approach to choose, ultimately resulting in a benefit for patients with PEX syndrome who require cataract surgery.\n\nThe main questions are:\n\nIs there a difference in lens tilt and decentration between the both methods. Is there a difference in the frequency and amount of capsular phimosis between the both methods.",[28,105],"Pseudoexfoliation Syndrome",[107,108,109,110,111],"Femtolaser","Sulcus-IOL","Anterior segment","Lens tilt and decentration","Capsular phimoses","2023-10-20",{"date":114,"type":33},"2023-10-24",{"date":116,"type":33},"2023-09-18",{"date":118,"type":22},"2030-08",{"name":39,"class":40}]