[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"aids-acquired-immune-deficiency-syndrome\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:aids-acquired-immune-deficiency-syndrome":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,44],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":5},"100619020","hiv-suicide-prevention-with-ai-dbt-100619020",false,"NCT07339189","HIV Suicide Prevention With AI-DBT","Piloting AI-Delivered Dialectical Behavioral Therapy for Suicide Prevention in Older Patients Living With HIV","Inclusion Criteria:\n\n* Aged 50+\n* evidence of suicide risk as defined by at least one of the following: PHQ-9 suicide item \\> 0, Ask Suicide Questions (ASQ, an NIMH-supported suicide risk screener with a version tailored for primary care) \\> 0, expression of suicidal thoughts to the provider during appointment, a suicide attempt in the past year, or PHQ-9 total score ≥ 8,\n* ability to read and communicate fluently in English or Spanish\n* not at imminent risk for suicide (does not have significant intent to die within 48 hours)\n* has a smartphone capable of texting and accessing the internet.\n\nExclusion Criteria:\n\n* deemed clinically inappropriate to participate because of severe psychosis, severe substance use, or severe cognitive deficits that would interfere with their comprehending study and intervention material.","ALL","50 Years",{"count":19,"type":20},50,"ESTIMATED","INTERVENTIONAL",[23],"NA","One in four older persons living with HIV\u002FAIDS (PLWHA) report at least one suicide attempt in their lifetime, and the risk for death by suicide is 100 times higher in PLWHA than in the general population. Currently, there are no behavioral interventions that specifically address suicide prevention for older PLWHA, despite their unique biopsychosocial and structural risk factors. Through this work, investigators will adapt Dialectical Behavior Therapy, an evidence-based intervention for suicide prevention, for patients with PLWHA to be delivered by an AI-powered conversational Agent developed by our industry partner, Empower Health. Investigators will then pilot test the feasibility, usability, acceptability and preliminary efficacy to improve self-efficacy to manage negative emotions in n=50 older adults living with HIV\u002FAIDS.",[26,27,28],"Suicidal Ideation and Behavior","HIV","AIDS (Acquired Immune Deficiency Syndrome)",[30,27,31],"suicide","mHealth","RECRUITING","2026-01-14",{"date":35,"type":36},"2026-01-15","ACTUAL",{"date":38,"type":36},"2026-01-07",{"date":40,"type":20},"2028-06",{"name":42,"class":43},"Rutgers, The State University of New Jersey","OTHER",{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":48,"acronym":4,"eligibilityCriteria":49,"healthyVolunteers":50,"sex":16,"minAge":51,"maxAge":4,"enrollmentInfo":52,"targetDuration":4,"studyType":21,"phases":54,"briefSummary":55,"conditions":56,"keywords":63,"overallStatus":70,"whyStopped":4,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":80},"100609844","evaluating-a-clinical-decision-support-tool-for-antiretroviral-therapy-optimization-100609844","NCT07219862","Evaluating a Clinical Decision Support Tool for Antiretroviral Therapy Optimization","Inclusion Criteria:\n\nHIV patients\n\n1. Documented HIV-1 infection\n2. Greater than 18 years of age\n3. Genotype resistance testing previously conducted or scheduled through clinical care\n\nProviders:\n\nHIV care providers who will determine treatment selections, with or without utilizing our clinical decision support tool\n\nExclusion Criteria:\n\nHIV patients:\n\n1\\. Refusal or inability to give informed consent\n\nProviders:\n\n1\\. Refusal to give informed consent",true,"18 Years",{"count":53,"type":20},250,[23],"This study is testing software designed to help healthcare providers choose the best HIV treatment combinations for their patients. HIV medicines, known as antiretroviral therapy (ART), can be complex to manage because the right regimen depends on many factors-such as drug resistance, other health conditions, and medication schedules. Many people with HIV are cared for by general clinicians who may not have access to HIV specialists, which can make treatment decisions more challenging.\n\nIn this study, healthcare providers will use patient cases to compare standard HIV treatment resources with a new clinical decision support tool that gives evidence-based ART recommendations at the point of care.\n\nThe investigators hypothesize that using the tool will help providers select treatment plans that better match clinical guidelines, make decisions faster, reduce mental effort, and increase overall satisfaction with the prescribing process.",[57,58,59,60,28,61,62],"HIV (Human Immunodeficiency Virus)","Clinical Decision Support System (CDSS)","Antiretroviral Therapy, Highly Active","INDIVIDUALIZED THERAPY","Personalized Medicine","Precision Medicine",[64,65,66,67,68,69],"hiv","clinical decision support system","antiretroviral therapy","aids","personalized medicine","precision medicine","NOT_YET_RECRUITING","2025-10-20",{"date":73,"type":36},"2025-10-22",{"date":75,"type":20},"2028-09-01",{"date":77,"type":20},"2031-09-01",{"name":79,"class":43},"Keck School of Medicine of USC",1]