[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"airway-management\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:airway-management":28},{"pageToken":4,"total":5,"offset":6,"count":7,"results":8},null,37,0,25,[9,50,81,94,127,155,184,209,233,262,291,313,341,370,395,421,447,479,501,531,555,580,604,625,652],{"id":10,"slug":11,"hasResults":12,"nctId":13,"briefTitle":14,"officialTitle":15,"acronym":4,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":29,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100053415","blind-intubation-through-the-tulip-airway-versus-direct-laryngoscopy-100053415",false,"NCT07681453","Blind Intubation Through the Tulip Airway Versus Direct Laryngoscopy","Comparison of Blind Endotracheal Intubation Through the Tulip Oropharyngeal Airway and Direct Laryngoscopy by Novice Operators: A Randomized Crossover Manikin Study","Inclusion Criteria:\n\n* Voluntary participation in the study\n* Anesthesia technician students with no prior airway management experience\n* Age ≥ 18 years\n* Willingness to participate in simulation-based intubation procedures\n\nExclusion Criteria:\n\n* Prior advanced airway management experience (e.g., regular intubation practice in clinical settings)\n* Refusal to participate or withdraw consent\n* Inability to complete simulation procedures for any reason",true,"ALL","18 Years",{"count":21,"type":22},60,"ESTIMATED","INTERVENTIONAL",[25],"NA","This is a randomized crossover mannequin study comparing two airway management techniques in novice operators: blind endotracheal intubation via the Tulip oropharyngeal airway versus direct laryngoscopy. The study aims to evaluate and compare the success rate and performance characteristics of both methods under simulated conditions in order to assess their effectiveness in airway management training and practice.",[28],"Airway Management",[30,31,32,33,34,35,36],"Airway management","endotracheal intubation","Tulip airway","direct laryngoscopy","simulation study","crossover trial","anesthesia education","RECRUITING","2026-07-10",{"date":40,"type":41},"2026-07-13","ACTUAL",{"date":43,"type":41},"2026-07-06",{"date":45,"type":22},"2026-08-10",{"name":47,"class":48},"Ankara Etlik City Hospital","OTHER_GOV",1,{"id":51,"slug":52,"hasResults":12,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":4,"eligibilityCriteria":56,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":57,"enrollmentInfo":58,"targetDuration":4,"studyType":23,"phases":60,"briefSummary":61,"conditions":62,"keywords":65,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":49},"100053988","comparison-of-three-airway-intubation-devices-for-first-attempt-success-in-general-anesthesia-patients-100053988","NCT07699653","Comparison of Three Airway Intubation Devices for First-Attempt Success in General Anesthesia Patients","Application of SPHJ-II, Visual Lighted Stylet, and Visual Intubation Fiberscope in Endotracheal Intubation in Patients Under General Anesthesia","Inclusion Criteria:\n\n* Age 18 to 65 years, inclusive. American Society of Anesthesiologists (ASA) physical status I to III. Scheduled for surgery under general anesthesia requiring endotracheal intubation.\n\nThe participant or legally authorized representative is fully informed of the purpose, methods, potential risks, and possible benefits of the study and provides written informed consent.\n\nExclusion Criteria:\n\n* Anticipated severe difficulty with mask ventilation, such as severe obesity (BMI \\> 35 kg\u002Fm²) with obstructive sleep apnea syndrome, history of neck radiotherapy, craniofacial malformation, or other conditions judged by the attending anesthesiologist to confer high risk for mask ventilation, and patients requiring awake tracheal intubation.\n\nCervical spine instability, cervical trauma, rheumatoid arthritis involving the cervical spine, ankylosing spondylitis, or any condition requiring absolute cervical immobilization during the procedure.\n\nSignificant airway involvement identified preoperatively, including imaging evidence of tracheal narrowing with minimal diameter \\\u003C 5 mm, severe tracheal compression, displacement or collapse, stridor at rest or after activity, vocal cord paralysis with dyspnea, giant thyroid mass with orthopnea, or other oral, pharyngeal, or laryngeal tumor, edema, stenosis, abscess, or severe upper airway anatomical abnormality affecting glottic exposure or endotracheal tube passage.\n\nHigh risk of reflux and aspiration. Severe cardiovascular disease, severe respiratory disease, severe hepatic or renal dysfunction, severe coagulation disorder, frailty, pregnancy or breastfeeding, or known allergy.\n\nAny other condition making the patient unsuitable for participation in the study, such as psychiatric illness, communication disorder, or poor compliance.","65 Years",{"count":59,"type":22},549,[25],"The goal of this clinical trial is to compare three airway intubation devices in adult patients undergoing general anesthesia who require tracheal intubation. The main questions it aims to answer are:\n\n* Does the SPHJ-II video-assisted adjustable red-light fluoroscopic tracheal intubation scope improve first-attempt intubation success compared with a visual lighted stylet and a visual intubation fiberscope?\n* How do the three devices compare in intubation efficiency, intubation-related complications, and peri-intubation physiological responses?\n\nResearchers will compare the SPHJ-II, the visual lighted stylet, and the visual intubation fiberscope to evaluate their performance during tracheal intubation.\n\nParticipants will be randomly assigned to one of the three device groups and undergo tracheal intubation during general anesthesia using the assigned device.",[28,63,64],"General Anesthesia","Tracheal Intubation",[66,67,68,69,70],"SPHI-II","Visual lighted stylet","Visual intubation fiberscope","First-attempt intubation success","Randomized controlled trial","NOT_YET_RECRUITING","2026-07-08",{"date":40,"type":41},{"date":75,"type":22},"2026-07",{"date":77,"type":22},"2026-12-31",{"name":79,"class":80},"Guangzhou University of Chinese Medicine","OTHER",{"id":82,"slug":4,"hasResults":12,"nctId":13,"briefTitle":14,"officialTitle":15,"acronym":4,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":83,"targetDuration":4,"studyType":23,"phases":84,"briefSummary":26,"conditions":85,"keywords":86,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":90,"completionDateStruct":91,"leadSponsor":92,"locationsCount":4},"100645407",{"count":21,"type":22},[25],[28],[30,31,32,33,34,35,36],"2026-06-26",{"date":89,"type":41},"2026-07-02",{"date":38,"type":22},{"date":45,"type":22},{"name":93,"class":80},"Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization",{"id":95,"slug":96,"hasResults":12,"nctId":97,"briefTitle":98,"officialTitle":99,"acronym":100,"eligibilityCriteria":101,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":102,"targetDuration":4,"studyType":23,"phases":104,"briefSummary":105,"conditions":106,"keywords":107,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":118,"lastUpdatePostDateStruct":119,"startDateStruct":121,"completionDateStruct":123,"leadSponsor":125,"locationsCount":49},"100639500","i-scoop-vs-c-mac-d-blade-videolaryngoscope-for-airway-management-under-spontaneous-breathing-and-analgosedation-100639500","NCT07624162","I-scoop vs. C-Mac D-Blade Videolaryngoscope for Airway Management Under Spontaneous Breathing and Analgosedation","Practicability of Airway Management With the Videolaryngoscopes I-scoop and C-Mac D-Blade Under Spontaneous Breathing and Analgosedation - A Prospective, Randomized, Monocentric Trial","OWN BREATH 2","Inclusion Criteria:\n\n* Age ≥ 18 years\n* Scheduled surgical procedure or intervention under general anesthesia\n* Capacity to give informed consent (free and independent decision-making capacity)\n* Willingness to provide written informed consent after comprehensive verbal and written information about study aims, procedures, and risks\n\nExclusion Criteria:\n\n* Lack of, or withdrawal of, written informed consent\n* Lack of capacity to consent or legal guardianship for health-related decisions\n* Insufficient German language skills for qualified verbal and written informed consent (exclusion to protect patients, since legally valid and substantively meaningful consent is not possible without secured language comprehension)\n* Pregnancy or breastfeeding\n* Current opioid therapy or chronic opioid therapy discontinued less than 1 month before the procedure\n* Known drug or alcohol dependence\n* Known hypersensitivity or allergy to lidocaine or its excipients (glycerol, propyl-4-hydroxybenzoate, methyl-4-hydroxybenzoate)\n* Severe psychiatric disorder impairing capacity to consent or to cooperate\n* Indication for nasal intubation\n* Non-pain-related limitation of mouth opening to less than 16 mm\n* Severe comorbidities with particular risk in the context of the study intervention (e.g., unstable cardiac or pulmonary disease, uncontrolled epilepsy)\n* Participation in another clinical study within the previous 30 days that could influence the present study question",{"count":103,"type":22},200,[25],"The purpose of this clinical trial is to investigate whether the videolaryngoscope i-scoop makes airway management under spontaneous breathing and analgosedation more clinically practicable than the established standard device, the C-Mac D-Blade videolaryngoscope, in adults undergoing surgery under general anesthesia.\n\nThe main questions it aims to answer are:\n\n• Is good clinical practicability - defined as a successful, easy, and complication-free intubation under spontaneous breathing - more frequently achieved with the i-scoop than with the C-Mac D-Blade?\n\nResearchers will compare the standardized airway management procedure under spontaneous breathing using either the i-scoop or the C-Mac D-Blade.\n\nParticipants will:\n\n* continue breathing on their own during the procedure\n* be randomly assigned (1:1) to one of the two videolaryngoscopes\n* receive standardized analgosedation and topical lidocaine anesthesia of the upper airway before the breathing tube is placed\n* be asked about discomfort and recall of the procedure after surgery (in the recovery room, on postoperative day 1, and at 7 days post-intubation) by a blinded interviewer",[28],[108,109,110,111,112,113,114,115,116,117],"Videolaryngoscope","i-scoop","C-Mac D-Blade","Spontaneous breathing","Conscious sedation","Analgosedation","Topical airway anesthesia","Bladeless laryngoscope","Anatomy-guided intubation","Clinical practicability","2026-06-20",{"date":120,"type":41},"2026-06-25",{"date":122,"type":41},"2026-06-18",{"date":124,"type":22},"2028-04-30",{"name":126,"class":80},"Hannover Medical School",{"id":128,"slug":129,"hasResults":12,"nctId":130,"briefTitle":131,"officialTitle":132,"acronym":4,"eligibilityCriteria":133,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":134,"enrollmentInfo":135,"targetDuration":4,"studyType":137,"phases":4,"briefSummary":138,"conditions":139,"keywords":143,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":148,"lastUpdatePostDateStruct":149,"startDateStruct":151,"completionDateStruct":152,"leadSponsor":153,"locationsCount":4},"100619603","evaluation-of-anterior-neck-ultrasound-in-predicting-difficult-airway-in-obese-patients-100619603","NCT07346768","Evaluation of Anterior Neck Ultrasound in Predicting Difficult Airway in Obese Patients","Ultrasound Assessment of Anterior Neck Soft Tissue Thickness to Predict Difficult Airway Risk in Obese Patients Undergoing for Surgery Under General Anesthesia: an Observational Study","Inclusion Criteria:\n\n* Age 18-70 years\n* ASA physical status I-III\n\n  \\* BMI \\>25 kg\u002Fm²\n* Scheduled for elective surgery under general anesthesia\n\nExclusion Criteria:\n\n* Emergency surgery\n* Pregnancy\n* Maxillofacial anomalies or neck masses\n* Rapid sequence induction\n* Previous history of difficult intubation\n* BMI \\>60 kg\u002Fm²","70 Years",{"count":136,"type":22},52,"OBSERVATIONAL","Obese patients are at increased risk of difficult airway management due to anatomical changes in the anterior neck soft tissues. Accurate preoperative prediction of difficult airway remains challenging using conventional clinical airway assessment tests alone.\n\nThis prospective observational study aims to evaluate the role of ultrasound assessment of anterior neck soft tissue thickness in predicting difficult airway risk in overweight and obese adult patients undergoing elective surgery under general anesthesia. Ultrasound-based anterior neck measurements will be compared with standard clinical airway assessment parameters to determine their diagnostic accuracy for difficult laryngoscopy and intubation.\n\nThe results of this study may contribute to improved preoperative airway risk stratification and safer airway management in obese patients.",[140,28,141,142],"Ultrasonography","Intubation, Intratracheal","Obesity and Overweight",[144,145,146,147],"Obesity","difficult airway","anterior neck ultrasound","ultrasonography","2026-06-12",{"date":150,"type":41},"2026-06-16",{"date":118,"type":22},{"date":118,"type":22},{"name":154,"class":80},"Gaziantep City Hospital",{"id":156,"slug":157,"hasResults":12,"nctId":158,"briefTitle":159,"officialTitle":160,"acronym":161,"eligibilityCriteria":162,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":163,"targetDuration":4,"studyType":23,"phases":164,"briefSummary":165,"conditions":166,"keywords":170,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":175,"lastUpdatePostDateStruct":176,"startDateStruct":178,"completionDateStruct":180,"leadSponsor":182,"locationsCount":49},"100639898","mental-rehearsal-in-emergency-cricothyroidotomy-training-100639898","NCT07625072","Mental Rehearsal in Emergency Cricothyroidotomy Training","Effect of Mental Rehearsal Training on the Effectiveness of Emergency Cricothyroidotomy Training Among Medical Personnel.","MERIT","Inclusion Criteria:\n\n* Medical personnel, including anesthesiology and intensive care specialists, residents, and nursing staff employed within Anesthesiology and Intensive Care Departments of the Medical University of Warsaw network.\n* No prior experience with the use of Mental Rehearsal techniques in performing emergency cricothyroidotomy.\n* Informed consent.\n\nExclusion Criteria:\n\n* Medical personnel involved in the training process of study participants in emergency cricothyroidotomy, including instructors, assisting staff, and examiners.\n* Previous experience with the use of Mental Rehearsal techniques for acquiring competencies in performing emergency cricothyroidotomy.\n* Lack of informed consent.",{"count":21,"type":22},[25],"Medical staff at the clinic will participate in standard cricothyroidotomy training supplemented with structured mental rehearsal exercises in order to evaluate the usefulness and effectiveness of this approach as a training tool.",[167,168,28,169],"Difficult Airway","Medical Training","Cricothyroidotomy",[171,172,173,169,28,174],"Mental Rehearsal","Mental Training","eFONA (Emergency Front of Neck Airway)","Critical care","2026-06-01",{"date":177,"type":41},"2026-06-04",{"date":179,"type":22},"2026-06-08",{"date":181,"type":22},"2028-05-01",{"name":183,"class":80},"Medical University of Warsaw",{"id":185,"slug":186,"hasResults":12,"nctId":187,"briefTitle":188,"officialTitle":189,"acronym":4,"eligibilityCriteria":190,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":191,"enrollmentInfo":192,"targetDuration":4,"studyType":23,"phases":194,"briefSummary":195,"conditions":196,"keywords":198,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":201,"lastUpdatePostDateStruct":202,"startDateStruct":204,"completionDateStruct":205,"leadSponsor":207,"locationsCount":4},"100639566","multifunctional-oropharyngeal-airway-and-hypoxemia-in-sedated-gi-endoscopy-a-multicenter-rct-100639566","NCT07623863","Multifunctional Oropharyngeal Airway and Hypoxemia in Sedated GI Endoscopy: A Multicenter RCT","Effect of a Novel Multifunctional Oropharyngeal Airway on Hypoxemia in Patients Undergoing Sedated Gastrointestinal Endoscopy: A Multicenter, Prospective, Randomized Controlled Trial","Inclusion Criteria:\n\n* Age 18-80 years;\n* BMI: 18-30 kg\u002Fm²;\n* ASA class I-II;\n* Scheduled to undergo elective sedated gastrointestinal endoscopy;\n* Willing to participate in this study and able to provide written informed consent.\n\nExclusion Criteria:\n\n* Diagnosed respiratory diseases, including asthma, bronchitis, chronic obstructive pulmonary disease (COPD), emphysema, moderate or severe obstructive sleep apnea (OSA), pulmonary embolism, pulmonary edema, lung cancer, or upper respiratory tract infection, etc.;\n* Coagulation disorders, tendency for oral\u002Fnasal bleeding, mucosal injury, or space-occupying lesions;\n* Severe cardiac insufficiency (≤4 MetS);\n* Severe renal insufficiency (acute kidney injury \\[AKI\\] or chronic kidney disease \\[CKD\\] stage 4 or higher);\n* Severe hepatic insufficiency (Child-Pugh class C or worse);\n* Planned therapeutic endoscopy (e.g., polypectomy, endoscopic mucosal resection \\[EMR\\], or other therapeutic procedures);\n* Pregnancy or breastfeeding;\n* Allergy to the study drugs;\n* Emergency surgery;\n* Daily alcohol intake ≥60 grams;\n* History of psychiatric disorders: e.g., depression, severe central nervous system depression, Parkinson's disease, basal ganglia lesions, schizophrenia, epilepsy, Alzheimer's disease;\n* Myasthenia gravis;\n* Participation in other related clinical trials within the past 3 months;\n* Refusal to participate.","80 Years",{"count":193,"type":22},1518,[25],"This multicenter, prospective, randomized controlled trial aims to evaluate whether a novel multifunctional oropharyngeal airway (MOPA) reduces the incidence of hypoxemia in 1,518 adult patients (ASA I-II, aged 18-80 years) undergoing elective sedated gastrointestinal endoscopy. Patients are randomized 1:1 to receive either the MOPA (which integrates oxygen delivery, PETCO₂ monitoring, and airway support) or conventional nasal cannula with standard mouthpiece. The primary endpoint is the incidence of hypoxemia (75% ≤ SpO₂ \\\u003C 90% for \\\u003C60 seconds) during the procedure. Secondary outcomes include severe hypoxemia, hypercapnia, PETCO₂ monitoring success, airway interventions, adverse events, and satisfaction scores. The study is conducted across 29 centers in China, with centralized randomization via an EDC system, blinded outcome assessment, and statistical analysis using a two-sided alpha of 0.05 (power 90%). Results are expected to provide high-level evidence for optimizing airway management during sedated endoscopy.",[197,28],"Hypoxemia",[199,200,30,70],"Novel multifunctional oropharyngeal airway","Capnography \u002F PETCO₂ monitoring","2026-05-28",{"date":203,"type":41},"2026-06-03",{"date":175,"type":22},{"date":206,"type":22},"2028-06-01",{"name":208,"class":80},"Qianfoshan Hospital",{"id":210,"slug":211,"hasResults":12,"nctId":212,"briefTitle":213,"officialTitle":214,"acronym":215,"eligibilityCriteria":216,"healthyVolunteers":12,"sex":18,"minAge":4,"maxAge":217,"enrollmentInfo":218,"targetDuration":4,"studyType":23,"phases":220,"briefSummary":221,"conditions":222,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":223,"lastUpdatePostDateStruct":224,"startDateStruct":226,"completionDateStruct":228,"leadSponsor":230,"locationsCount":232},"100513594","laryngoscopy-for-neonatal-and-infant-airway-management-with-supplemental-oxygen-at-different-flow-rates-optimise-2-100513594","NCT05967507","Laryngoscopy for Neonatal and Infant Airway Management wIth Supplemental Oxygen at Different Flow Rates (OPTIMISE-2)","Laryngoscopy for Neonatal and Infant Airway Management wIth Supplemental Oxygen at Different Flow Rates (OPTIMISE-2): a Multi-center, Non-inferiority, Prospective Randomized Controlled Trial","OPTIMISE-2","Inclusion Criteria:\n\n* Pediatric patients requiring oral or nasal tracheal intubation for elective, semi-elective, or urgent surgical and non-surgical indications.\n* Neonates and infants up to 52 weeks postconceptual age, with legal guardians providing written informed consent before the intervention\n\nExclusion Criteria:\n\n* Prediction of difficult intubation upon physical examination or previous history of difficult intubation, mandating a technique different than direct laryngoscopy to secure the airway;\n* Congenital heart disease demanding FiO2 \\\u003C 1.0\n* Cardiopulmonary collapse requiring advanced life support\n* Intubation for emergency surgical and non-surgical indications.","52 Weeks",{"count":219,"type":22},1192,[25],"This study aims to investigate the optimal oxygen flow rate needed during tracheal intubation with the C-MAC video laryngoscope (Karl Storz, Tuttlingen, Germany) using Miller-blade or Macintosh-blade size No. 0 or No. 1 in the operating room or intensive care unit. The investigators hypothesize that the difference between low-flow and high-flow supplemental oxygen is negligible.",[28],"2026-05-09",{"date":225,"type":41},"2026-05-12",{"date":227,"type":41},"2023-12-01",{"date":229,"type":22},"2027-09",{"name":231,"class":80},"Thomas Riva",11,{"id":234,"slug":235,"hasResults":12,"nctId":236,"briefTitle":237,"officialTitle":238,"acronym":4,"eligibilityCriteria":239,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":240,"targetDuration":242,"studyType":137,"phases":4,"briefSummary":243,"conditions":244,"keywords":247,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":253,"lastUpdatePostDateStruct":254,"startDateStruct":256,"completionDateStruct":258,"leadSponsor":260,"locationsCount":49},"100639089","taiwan-ed-airway-quality-surveillance-registry-tear-100639089","NCT07574450","Taiwan ED Airway Quality Surveillance Registry (TEAR)","The Taiwan ED Airway Quality Surveillance Registry (TEAR): A Prospective Multicenter Observational Study","Inclusion Criteria:\n\n* Undergoing tracheal intubation in the emergency department during the study period\n\nExclusion Criteria:\n\n* Prehospital intubation; intubation performed solely for elective anesthesia\u002Fprocedural sedation outside emergency indications",{"count":241,"type":22},1200,"1 Month","This prospective, multicenter observational registry systematically captures all emergency department tracheal intubations across participating hospitals in Taiwan. The registry focuses on process quality indicators, including first-pass success, and patient-safety outcomes, including hypoxemia, hypotension, and peri-intubation cardiac arrest within 30 minutes of intubation. Routinely generated laboratory and physiologic variables are also collected to improve risk stratification and identify predictors of major adverse events. The study is non-interventional and does not alter clinical care.",[28,64,245,246],"Emergency Department","Peri-intubation Adverse Events",[248,249,250,251,252],"first-pass success","hypoxemia","hypotension","cardiac arrest","registry","2026-05-05",{"date":255,"type":41},"2026-05-08",{"date":257,"type":22},"2026-08",{"date":259,"type":22},"2029-12",{"name":261,"class":80},"Chang Gung Memorial Hospital",{"id":263,"slug":264,"hasResults":12,"nctId":265,"briefTitle":266,"officialTitle":267,"acronym":4,"eligibilityCriteria":268,"healthyVolunteers":12,"sex":18,"minAge":269,"maxAge":270,"enrollmentInfo":271,"targetDuration":4,"studyType":23,"phases":273,"briefSummary":275,"conditions":276,"keywords":279,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":253,"lastUpdatePostDateStruct":284,"startDateStruct":285,"completionDateStruct":287,"leadSponsor":289,"locationsCount":49},"100639649","phase-4-effective-dose-of-alfentanil-combined-with-propofol-for-laryngeal-mask-airway-insertion-in-children-100639649","NCT07581665","Effective Dose of Alfentanil Combined With Propofol for Laryngeal Mask Airway Insertion in Children","Effective Dose of Alfentanil Combined With Propofol for Laryngeal Mask Airway Insertion in Children: A Prospective, Up-and-Down Sequential Allocation Study","Inclusion Criteria:\n\n* Aged 7 to 12 years\n* Undergoing elective day surgery\n* ASA physical status I-II\n* Body Mass Index (BMI) between 14 and 24 kg\u002Fm²\n* Accompanied by a fully capable guardian within 24 hours after discharge\n\nExclusion Criteria:\n\n* Allergy to opioids\n* Unresolved upper respiratory tract infection within the past 1 week\n* Abnormal heart, lung, liver, or kidney function, or metabolic diseases\n* Airway anatomical abnormalities (e.g., micrognathia, laryngomalacia, macroglossia) or OSAHS (Obstructive Sleep Apnea-Hypopnea Syndrome)\n* Use of analgesics, sedatives, or other psychotropic drugs within the past 2 weeks\n* Refusal to sign the informed consent form","7 Years","12 Years",{"count":272,"type":22},40,[274],"PHASE4","This study uses a prospective, up-and-down sequential allocation method to determine the median effective dose (ED50) and 95% effective dose (ED95) of alfentanil combined with propofol for successful laryngeal mask airway (LMA) insertion in children aged 7-12 undergoing elective day surgery.",[277,28,63,278],"Pediatric Anesthesia","LMA",[280,281,277,278,282,283],"Alfentanil","Propofol","Dixon Method","Effective dose",{"date":225,"type":41},{"date":286,"type":22},"2026-05-01",{"date":288,"type":22},"2027-03-30",{"name":290,"class":80},"Zhongshan Ophthalmic Center, Sun Yat-sen University",{"id":292,"slug":293,"hasResults":12,"nctId":294,"briefTitle":295,"officialTitle":296,"acronym":4,"eligibilityCriteria":297,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":298,"enrollmentInfo":299,"targetDuration":4,"studyType":137,"phases":4,"briefSummary":301,"conditions":302,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":286,"lastUpdatePostDateStruct":305,"startDateStruct":307,"completionDateStruct":309,"leadSponsor":311,"locationsCount":49},"100569977","upper-airway-ultrasound-evaluation-100569977","NCT06701253","Upper Airway Ultrasound Evaluation","Ultrasound of the Anterior Neck Tissues, as a New Tool in the Evaluation of Difficult Airway.","Inclusion Criteria: age\\>18, elective surgery under general anesthesia with endotracheal intubation\n\nExclusion Criteria:\n\n* obstetric surgeries,\n* pregnancy,\n* non elective surgeries,\n* patients with previous surgeries involving the anterior surface of the neck (i.e., thyroid surgery),\n* patients with history of cervical radiation.","99 Years",{"count":300,"type":22},500,"Current guidelines support the use of predictive clinical tests in the evaluation of difficult airway, meaning either difficult bag and mask ventilation, conventional laryngoscopy and\u002For endotracheal intubation. However, despite the clinical use of these predictive tests, unpredictive difficult laryngoscopy complicates 1.5-13% of cases. Life threatening scenarios may be encountered in patients with difficult or impossible bag and mask ventilation.\n\nAnaesthesiologists are familiar with the use of ultrasound, with peripheral nerve blockade and central vascular access representing the most popular applications during the last decades. The ultrasound provides real time and accurate images. According to the current literature, there are only a handful of studies relevant to the application of point of care ultrasound (POCUS), as a new tool in the upper airway evaluation. It is a new field of research with high interest.\n\nThis is a prospective observational study to investigate if specific ultrasound measurements of the anterior neck can serve as predictors of difficult airway. The ultrasound parameters will be measured preoperatively, during the preanaesthetic evaluation, along with standard clinical prognostic tools, like the mallampati score. The ultrasound parameters to be investigated are:\n\n1. the distance from thyroid isthmus to skin surface,\n2. the distance from the hyoid bone to the skin surface,\n3. the distance from the anterior commissure of vocal cords to the skin surface,\n4. the distance from skin to the trachea at the level of jugular notch,\n5. the distance from skin to epiglottis corresponding to half of the distance between thyroid cartilage and hyoid bone,\n6. and the angle between glottis and epiglottis. After the induction in anaesthesia, the Cormack Lehane score (grading of the laryngoscopy view) and the Han scale (grading of the degree of difficulty of bag and mask ventilation) will also be recorded.\n\nThe goal of this study is the investigation of the role of POCUS in the evaluation of difficult bag and mask ventilation and difficult intubation. The primary endpoint is the incidence of difficult bag and mask ventilation and the incidence of difficult laryngoscopy and intubation. Secondary endpoints are the correlations between clinical prognostic tools of difficult airway and the POCUS parameters under investigation.",[28,303,304],"Point of Care","Ultrasound",{"date":306,"type":41},"2026-05-04",{"date":308,"type":41},"2021-11-08",{"date":310,"type":22},"2028-06-09",{"name":312,"class":80},"University of Ioannina",{"id":314,"slug":315,"hasResults":12,"nctId":316,"briefTitle":317,"officialTitle":318,"acronym":4,"eligibilityCriteria":319,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":320,"enrollmentInfo":321,"targetDuration":4,"studyType":23,"phases":323,"briefSummary":324,"conditions":325,"keywords":326,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":331,"lastUpdatePostDateStruct":332,"startDateStruct":334,"completionDateStruct":336,"leadSponsor":338,"locationsCount":340},"100579562","lma-i-gel-versus-lma-protector-during-minor-urological-procedures-under-general-anesthesia-in-adult-patients-100579562","NCT06825910","LMA I-Gel Versus LMA Protector During Minor Urological Procedures Under General Anesthesia in Adult Patients","Laryngeal Mask Airway I-Gel and Laryngeal Mask Airway Protector for Minor Urological Procedures Under General Anesthesia in Adult Patients: A Randomized Comparative Study","Inclusion Criteria:\n\n* ASA I-II\n* Patients older than 18 years\n* Procedures in supine and lithotomy position\n\nExclusion Criteria:\n\n* Tumors or anatomical anomalies of the upper airway\n* Known history of difficult intubation\n* Limited mouth opening less than 2cm\n* Decreased compliance of the lungs or the thoracic cage\n* Need of mechanical ventilation after the surgery","90 Years",{"count":322,"type":22},100,[25],"This will be a randomized comparative study comparing the two supraglottic devices i-gel and Protector, intraoperatively, during minor urological procedures under general anesthesia in adult patient.",[28,63],[278,327,328,329,330],"Protector","Airway Device Evaluation","iGel","Airway Device Comparison","2026-04-24",{"date":333,"type":41},"2026-04-27",{"date":335,"type":41},"2025-02-01",{"date":337,"type":22},"2026-12-30",{"name":339,"class":80},"Nikolopoulou Maria Zozefin",2,{"id":342,"slug":343,"hasResults":12,"nctId":344,"briefTitle":345,"officialTitle":346,"acronym":4,"eligibilityCriteria":347,"healthyVolunteers":17,"sex":18,"minAge":348,"maxAge":349,"enrollmentInfo":350,"targetDuration":351,"studyType":137,"phases":4,"briefSummary":352,"conditions":353,"keywords":357,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":362,"lastUpdatePostDateStruct":363,"startDateStruct":365,"completionDateStruct":367,"leadSponsor":369,"locationsCount":49},"100633151","comparison-of-two-airway-devices-i-gel-and-air-q-in-children-aged-1-10-years-during-general-anesthesia-100633151","NCT07522957","Comparison of Two Airway Devices (I-Gel and Air-Q) in Children Aged 1-10 Years During General Anesthesia","Effect of I-gel and Air-Q SP LMAs on Oropharyngeal Leak Pressure and Gastric Insufflation in Children: An Ultrasonography-Guided Randomized Study","Inclusion Criteria:\n\n* Children aged 1-10 years\n* American Society of Anesthesiologists (ASA) physical status I-II\n* Scheduled for elective (non-emergency) surgery under general anesthesia\n* Planned use of a supraglottic airway device for airway management\n* Written informed consent obtained from a parent or legal guardian\n\nExclusion Criteria:\n\n* History of conditions associated with increased risk of aspiration (e.g., gastroesophageal reflux)\n* Known or predicted difficult airway (e.g., Mallampati score ≥ 3)\n* Congenital or acquired abnormalities of the face, neck, or upper airway\n* Active upper respiratory tract infection\n* Presence of significant pulmonary disease (e.g., asthma, bronchopulmonary dysplasia, cystic fibrosis)\n* Body mass index above the 95th percentile for age (morbid obesity)\n* Emergency surgery\n* Previous complications related to supraglottic airway device use\n* Failure of device placement or need to switch to an alternative airway management technique\n* Refusal of participation by parent or legal guardian","1 Year","10 Years",{"count":21,"type":22},"1 Day","This study aims to compare two commonly used airway devices (I-gel and Air-Q) in children aged 1-10 years undergoing general anesthesia for surgery. These devices help doctors keep the airway open and support breathing during the operation. The study will evaluate how well each device works, how easy they are to place, and whether they cause air to enter the stomach. Ultrasound will be used to safely check the position of the device and detect any air in the stomach. The results of this study may help improve the safety and effectiveness of airway management in children during anesthesia.",[354,140,355,28,356],"Anesthesia General","Laryngeal Mask Airways","Child",[30,358,359,140,360,361],"Laryngeal mask airway","Pediatric patients","Gastric insufflation","Supraglottic airway devices","2026-04-21",{"date":364,"type":41},"2026-04-23",{"date":366,"type":22},"2026-04",{"date":368,"type":22},"2026-05",{"name":47,"class":48},{"id":371,"slug":372,"hasResults":12,"nctId":373,"briefTitle":374,"officialTitle":375,"acronym":376,"eligibilityCriteria":377,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":378,"targetDuration":4,"studyType":137,"phases":4,"briefSummary":380,"conditions":381,"keywords":382,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":387,"lastUpdatePostDateStruct":388,"startDateStruct":389,"completionDateStruct":391,"leadSponsor":393,"locationsCount":49},"100635073","tmh-and-ultrasound-for-difficult-airway-prediction-100635073","NCT07547943","TMH And Ultrasound For Difficult Airway Prediction","Comparative Evaluation Of Thyromental Height And Ultrasonographic Airway Measurements In Predicting Difficult Airway: A Prospective Observational Study","TMH-USG","Inclusion Criteria:\n\nAdult patients aged 18 years and older Patients scheduled for elective surgery under general anesthesia Patients requiring endotracheal intubation Patients who provide written informed consent\n\nExclusion Criteria:\n\n* Patients with known upper airway pathology (e.g., tumor, trauma, infection) Patients with previous head and neck surgery or anatomical deformity affecting airway evaluation Patients with limited mouth opening (\\\u003C3 cm) or severe cervical spine restriction Patients with contraindications to ultrasonographic examination Patients requiring rapid sequence induction or emergency surgery Patients who refuse to participate",{"count":379,"type":22},240,"This prospective observational study aims to evaluate the predictive value of thyromental height (TMH) and ultrasonographic airway measurements in predicting difficult airway in adult patients undergoing elective surgery under general anesthesia.\n\nPreoperative airway assessment will include standard clinical evaluation, TMH measurement, and ultrasonographic measurements of anterior neck soft tissue. Perioperative airway management data, including intubation difficulty, number of attempts, and Cormack-Lehane classification, will be recorded.\n\nThe relationship between preoperative measurements and difficult airway will be analyzed to determine their predictive accuracy and clinical usefulness.",[167,28],[383,384,385,386],"Thyromental Height","Airway Ultrasound","Difficult Intubation","Cormack-Lehane","2026-04-17",{"date":364,"type":41},{"date":390,"type":22},"2026-05-15",{"date":392,"type":22},"2027-05-15",{"name":394,"class":48},"Bursa City Hospital",{"id":396,"slug":397,"hasResults":12,"nctId":398,"briefTitle":399,"officialTitle":400,"acronym":401,"eligibilityCriteria":402,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":57,"enrollmentInfo":403,"targetDuration":4,"studyType":23,"phases":405,"briefSummary":406,"conditions":407,"keywords":409,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":387,"lastUpdatePostDateStruct":414,"startDateStruct":415,"completionDateStruct":417,"leadSponsor":419,"locationsCount":49},"100612161","evaluation-of-sacovlm-video-laryngeal-mask-for-airway-management-in-military-medics-100612161","NCT07249983","Evaluation of SaCoVLM™ Video Laryngeal Mask for Airway Management in Military Medics","Evaluation of SaCoVLM™ Video Laryngeal Mask Airway for Airway Management by Inexperienced Military Medics: A Two-Phase Feasibility Study","SAVER","Inclusion Criteria:\n\n* Elective surgery\n* ASA I-II\n* need for airway management\n\nExclusion Criteria:\n\n* Pregnancy\n* known airway abnormalities\n* allergy to anesthetics",{"count":404,"type":22},50,[25],"A prospective, two-phase interventional study evaluating the performance, safety, and usability of the SaCoVLM™ video laryngeal mask airway for airway management by military medics with limited intubation experience. The study includes simulation-based training and clinical application in sedated patients undergoing elective surgery.",[28,64,408],"Anesthesia",[410,411,412,413],"SaCoVLM™","Video Laryngeal Mask","Military Medic Training","Emergency Airway",{"date":362,"type":41},{"date":416,"type":41},"2026-03-01",{"date":418,"type":22},"2027-01",{"name":420,"class":80},"Charles University, Czech Republic",{"id":422,"slug":423,"hasResults":12,"nctId":424,"briefTitle":425,"officialTitle":426,"acronym":4,"eligibilityCriteria":427,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":428,"targetDuration":4,"studyType":137,"phases":4,"briefSummary":430,"conditions":431,"keywords":436,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":438,"lastUpdatePostDateStruct":439,"startDateStruct":441,"completionDateStruct":443,"leadSponsor":445,"locationsCount":49},"100610009","induction-agent-choice-with-early-mortality-and-prognostic-outcomes-in-critically-ill-patients-100610009","NCT07222007","Induction Agent Choice With Early Mortality and Prognostic Outcomes in Critically Ill Patients","Association of Induction Agent Choice With Early Mortality and Prognostic Outcomes in Critically Ill Patients: A Large-Scale Retrospective Cohort Analysis","Inclusion Criteria:\n\n* Age ≥ 18 years\n* Admission to the surgical ICU for critical care\n* Administration of one of the studied induction agents\n* Availability of complete clinical data\n\nExclusion Criteria:\n\n* Age \\\u003C 18 years\n* Absence of documented induction agent administration\n* Incomplete or missing medical records",{"count":429,"type":22},4,"The aim of this retrospective cohort study is to compare the safety and efficacy of induction agents for tracheal intubation in critically ill adult patients.",[432,433,434,28,281,435],"Critically Ill","Intubation Complication","Oxygenation","Ketamine",[437],"intubation, critically ill patients, airway management","2026-04-11",{"date":440,"type":41},"2026-04-14",{"date":442,"type":22},"2026-04-18",{"date":444,"type":22},"2026-07-01",{"name":446,"class":48},"Zeliha Alicikus",{"id":448,"slug":449,"hasResults":12,"nctId":450,"briefTitle":451,"officialTitle":452,"acronym":453,"eligibilityCriteria":454,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":191,"enrollmentInfo":455,"targetDuration":4,"studyType":23,"phases":457,"briefSummary":458,"conditions":459,"keywords":463,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":470,"lastUpdatePostDateStruct":471,"startDateStruct":473,"completionDateStruct":475,"leadSponsor":477,"locationsCount":49},"100631498","ventilation-safety-in-beach-chair-shoulder-surgery-safelm-versus-i-gel-100631498","NCT07501468","Ventilation Safety in Beach Chair Shoulder Surgery: SafeLM Versus I-gel","Comparison of SafeLM™ Video Laryngeal Mask and I-gel® for Ventilation Safety After Transition to Beach Chair Position in Patients Undergoing Shoulder Surgery: A Prospective Randomized Controlled Study","SAFE-BCP","Inclusion Criteria:\n\n* Patients aged 18-80 years\n* American Society of Anesthesiologists (ASA) physical status I-III\n* Scheduled for elective shoulder surgery\n* Body mass index (BMI) between 18-40 kg\u002Fm\\^2\n* Adequate preoperative fasting (approximately 8 hours)\n* Ability and willingness to provide written informed consent\n\nExclusion Criteria:\n\n* Age \\\u003C18 or \\>80 years\n* Refusal to participate\n* ASA physical status \\>= IV\n* BMI \\>40 kg\u002Fm\\^2\n* Failure of supraglottic airway device placement after three attempts\n* Revision surgery\n* Multiple trauma\n* Maxillofacial fracture\n* Active malignancy receiving radiotherapy or chemotherapy\n* Active infection or ongoing antibiotic therapy (except prophylaxis)\n* Chronic steroid or immunosuppressive therapy\n* Full stomach\n* Gastroesophageal reflux disease\n* History of gastric surgery\n* Gastroparesis\n* Known egg allergy",{"count":456,"type":22},70,[25],"This study aims to compare the performance of SafeLM™ video laryngeal mask airway and i-gel® supraglottic airway device in patients undergoing shoulder surgery in the beach chair position under general anesthesia. The primary objective is to evaluate oropharyngeal leak pressure (OLP) within the first 10 minutes after transition to the beach chair position. Secondary objectives include assessment of ventilation safety, need for airway interventions, and postoperative airway-related complications. This prospective randomized study will provide data on the effectiveness and safety of a video-guided supraglottic airway device compared to a conventional device in a clinically challenging position.",[28,460,461,462],"Shoulder Surgery","General Anesthetic","Supraglottic Airway",[464,465,466,467,468,469],"Oropharyngeal Leak Pressure","SafeLM","i-gel","Ventilation Safety","Beach Chair Position","Video Laryngeal Mask Airway","2026-03-26",{"date":472,"type":41},"2026-03-30",{"date":474,"type":22},"2026-04-15",{"date":476,"type":22},"2026-09-15",{"name":478,"class":80},"Ankara City Hospital Bilkent",{"id":480,"slug":481,"hasResults":12,"nctId":482,"briefTitle":483,"officialTitle":483,"acronym":4,"eligibilityCriteria":484,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":485,"targetDuration":4,"studyType":23,"phases":487,"briefSummary":488,"conditions":489,"keywords":4,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":492,"lastUpdatePostDateStruct":493,"startDateStruct":495,"completionDateStruct":497,"leadSponsor":499,"locationsCount":4},"100631108","clinical-study-on-the-efficacy-of-subglottic-suction-in-mechanically-ventilated-patients-guided-by-bedside-ultrasound-100631108","NCT07496385","Clinical Study on the Efficacy of Subglottic Suction in Mechanically Ventilated Patients Guided by Bedside Ultrasound","Inclusion Criteria:\n\n* 1\\. Patients admitted to the ICU with the patient or their legal representative having signed an informed consent form; 2. Patients expected to have an oral artificial airway in place for ≥72 hours; 3. Patients using tracheostomy tubes with subglottic suctioning\n\nExclusion Criteria:\n\n* 1\\) Severe cervical deformity, extensive subcutaneous emphysema, thick dressing coverage, or severe obesity that prevents clear visualization of the subglottic region by ultrasound.\n\n  2\\) Coagulopathy (platelets \\\u003C50×10⁹\u002FL) or active bleeding tendency, which may induce airway bleeding due to suctioning procedures.\n\n  3\\) Presence of organic airway disease or previous cervical surgery history, affecting assessment of the subglottic region.\n\n  4\\) Tracheostomy patients. 5) Patients allergic to ultrasound coupling agents, or those unable to cooperate with cervical ultrasound examination due to severe agitation.\n\n  6\\) Patients with existing pulmonary infection upon admission. 7) Patients intubated for treatment of known aspiration. 8) History of lung cancer or head and neck cancer that may produce alpha-amylase in the lungs.\n\n  9\\) History of conditions affecting salivary secretion (e.g., Sjögren's syndrome).",{"count":486,"type":22},321,[25],"Subglottic suctioning, as an important airway management technique, has its operational accuracy and safety directly impacting patient prognosis. Therefore, improving the effectiveness and safety of subglottic suctioning has become a focus of clinical attention. Point-of-care ultrasound, which can provide imaging, can be used to guide subglottic suctioning, enhancing the intuitiveness of the procedure. This study aims to evaluate the safety and effectiveness of subglottic suctioning guided by point-of-care ultrasound in mechanically ventilated patients, in order to help standardize clinical practice and improve medical quality.",[490,491,28],"Ultrasound Guidance","Subglottic Airway Injury","2026-03-22",{"date":494,"type":41},"2026-03-27",{"date":496,"type":22},"2026-04-01",{"date":498,"type":22},"2027-08-01",{"name":500,"class":80},"Ruijin Hospital",{"id":502,"slug":503,"hasResults":12,"nctId":504,"briefTitle":505,"officialTitle":506,"acronym":507,"eligibilityCriteria":508,"healthyVolunteers":17,"sex":18,"minAge":509,"maxAge":510,"enrollmentInfo":511,"targetDuration":4,"studyType":23,"phases":513,"briefSummary":514,"conditions":515,"keywords":518,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":523,"lastUpdatePostDateStruct":524,"startDateStruct":526,"completionDateStruct":527,"leadSponsor":529,"locationsCount":49},"100619946","pediatric-airway-noninferiority-trial-of-devices-for-intubation-assessment-100619946","NCT07351227","Pediatric Airway: Noninferiority Trial of Devices for Intubation Assessment","Comparison of the Effectiveness and Cost-Effectiveness of McGRATH™ MAC and Besdata Videolaryngoscopes in the Orotracheal Intubation of Children: A Non-Inferiority Randomized Clinical Trial","PANDA","Inclusion Criteria:\n\n* The study will include children aged between 6 months and 3 years who are scheduled for elective surgery under general anesthesia at the Children's Institute (Instituto da Criança - ICr) of the Hospital das Clínicas Complex, University of São Paulo Medical School (HC-FMUSP), provided that informed consent is obtained from their parents or legal guardians.\n\nExclusion Criteria:\n\n* Patients under one year of age will be excluded if informed consent is not obtained from their legal guardians, if they are classified as ASA physical status IV or higher, present with hemodynamic instability, or have craniofacial abnormalities or oral deformities suggestive of a potentially difficult airway.","6 Months","3 Years",{"count":512,"type":22},226,[25],"The goal of this clinical trial is to find out whether the BESDATA BD-DF videolaryngoscope works as well as the McGRATH™ MAC videolaryngoscope for placing a breathing tube in infants during surgery. The study will also compare the costs associated with using each device.\n\nThe main questions this study aims to answer are:\n\nIs the BESDATA BD-DF videolaryngoscope as effective as the McGRATH™ MAC videolaryngoscope for successful placement of a breathing tube on the first attempt in infants?\n\nAre there differences between the two devices in terms of procedure time, number of attempts, airway-related complications, and overall costs?\n\nResearchers will compare infants who are intubated using the BESDATA BD-DF videolaryngoscope with infants who are intubated using the McGRATH™ MAC videolaryngoscope to see whether the two devices perform similarly and whether one is more cost-effective than the other.\n\nParticipants will:\n\nBe randomly assigned to have a breathing tube placed using one of the two videolaryngoscopes;\n\nReceive standard general anesthesia for an elective surgical procedure;\n\nHave information collected during and after the procedure to assess safety, effectiveness, and costs.",[141,28,516,517],"Video Laryngoscope","Cost Effectiveness",[108,519,520,521,522],"Pediatric orotracheal intubation","Cost effectiveness","McGrath MAC","BESDATA","2026-03-18",{"date":525,"type":41},"2026-03-20",{"date":416,"type":41},{"date":528,"type":22},"2027-12-31",{"name":530,"class":80},"University of Sao Paulo General Hospital",{"id":532,"slug":533,"hasResults":12,"nctId":534,"briefTitle":535,"officialTitle":536,"acronym":537,"eligibilityCriteria":538,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":539,"enrollmentInfo":540,"targetDuration":4,"studyType":137,"phases":4,"briefSummary":542,"conditions":543,"keywords":544,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":546,"lastUpdatePostDateStruct":547,"startDateStruct":549,"completionDateStruct":551,"leadSponsor":553,"locationsCount":340},"100620283","videolaryngoscopic-difficult-ntubation-and-glottic-view-score-a-multicentre-prospective-study-100620283","NCT07355608","Videolaryngoscopic Difficult ıntubation and Glottic View Score: A Multicentre Prospective Study","Prediction of Difficult Videolaryngoscopic Intubation and Development of a Dedicated Glottic View Score: A Multicentre Prospective Study","VIDIGLOV","Inclusion Criteria:\n\n* Adults\n* Both with normal or predicted difficult airways\n* Undergoing orotracheal intubation with a videolarygoscope\n\nExclusion Criteria:\n\n* Rapid sequence intubation\n* Double lumen tube intubation","100 Years",{"count":541,"type":22},4977,"Background:\n\nVideolaryngoscopy has improved glottic visualization and facilitated tracheal intubation. However, difficulties-including failed intubation-still occur. At present, no prospectively derived classification system exists to assess the difficulty of videolaryngoscopic (VL) intubation across both normal and anticipated difficult airways. Additionally, current glottic view grading systems, designed for direct laryngoscopy, may not adequately capture the specific challenges of VL intubation.\n\nObjectives:\n\nThis study aims to:\n\n1. Develop a predictive model for difficult VL intubation in surgical patients with both normal and anticipated difficult airways.\n2. Create a glottic view scoring system specifically tailored to videolaryngoscopy.\n3. Compare the predictive accuracy of the new scoring system with existing laryngeal view grades in forecasting difficult VL intubation.",[28],[30,108,545],"Difficult airway","2026-02-03",{"date":548,"type":41},"2026-02-05",{"date":550,"type":22},"2026-02-01",{"date":552,"type":22},"2027-02-01",{"name":554,"class":80},"Diskapi Teaching and Research Hospital",{"id":556,"slug":557,"hasResults":12,"nctId":558,"briefTitle":559,"officialTitle":560,"acronym":4,"eligibilityCriteria":561,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":57,"enrollmentInfo":562,"targetDuration":4,"studyType":23,"phases":563,"briefSummary":564,"conditions":565,"keywords":567,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":571,"lastUpdatePostDateStruct":572,"startDateStruct":574,"completionDateStruct":576,"leadSponsor":578,"locationsCount":49},"100619102","the-90-effective-ventilation-pressure-ep90-for-esophageal-insufflation-avoidance-during-anesthesia-induction-100619102","NCT07340255","The 90% Effective Ventilation Pressure (EP90) for Esophageal Insufflation Avoidance During Anesthesia Induction","The 90% Effective Ventilation Pressure (EP90) for Esophageal Insufflation Avoidance During Anesthesia Induction: A Bias-Coin Design With Up-and-Down Sequential Allocation Trial","Inclusion Criteria:\n\n1. Age: 18-65 years, regardless of gender;\n2. ASA classification: I-III;\n3. Scheduled for elective general anesthesia surgery;\n4. BMI: 18.0-28.0 kg\u002Fm²;\n5. Preoperative fasting: Solid food \\>6 hours, liquid \\>2 hours;\n6. Less than two from five criteria predicting difficult mask ventilation as described by Langeron et al.(Prediction of difficult mask ventilation. Anesthesiology 2000; 92:1229-36);\n7. No severe underlying conditions such as heart, lung, liver, or kidney disease;\n8. Signed informed consent and ability to cooperate with the study protocol.\n\nExclusion Criteria:\n\n1. Pregnant or breastfeeding women;\n2. History of upper gastrointestinal diseases such as gastroesophageal reflux disease, peptic ulcers, or hiatal hernia;\n3. Recent (within 2 weeks) respiratory infections, chronic cough, similar symptoms, and other known or predictable respiratory system diseases;\n4. Need for emergency surgery or airway obstruction after anesthesia induction requiring urgent intubation;\n5. Inability to achieve adequate oxygenation during mask ventilation (e.g., SpO₂ \\\u003C 92% for 30 seconds, unresponsive to treatment);\n6. History of contraindications or allergies to study medications;\n7. Inability to understand the study content or refusal to cooperate;\n8. Oropharyngeal or facial pathology;\n9. with an indwelling gastric tube, and who had previously undergone gastric surgery.",{"count":21,"type":22},[25],"Exploring the 90% Effective Ventilation Pressure (EP90) for Esophageal Insufflation Avoidance During Anesthesia Induction: The aim is to determine the optimal ventilation pressure for esophageal insufflation avoidance during anesthesia induction and to explore its guiding significance for anesthesia management. The goal is to provide a more precise and personalized ventilation pressure setting standard for clinical anesthesia, thereby enhancing the safety of the anesthesia induction phase.",[28,566],"Induction of Anesthesia",[568,28,569,570],"Esophageal Insufflation","Ventilation","Bias-coin Design","2026-01-13",{"date":573,"type":41},"2026-01-14",{"date":575,"type":41},"2025-09-29",{"date":577,"type":22},"2026-02",{"name":579,"class":80},"Affiliated Hospital of Jiaxing University",{"id":581,"slug":582,"hasResults":12,"nctId":583,"briefTitle":584,"officialTitle":585,"acronym":586,"eligibilityCriteria":587,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":588,"targetDuration":4,"studyType":23,"phases":590,"briefSummary":591,"conditions":592,"keywords":594,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":596,"lastUpdatePostDateStruct":597,"startDateStruct":599,"completionDateStruct":601,"leadSponsor":602,"locationsCount":49},"100611327","two-video-laryngoscopes-laringocel-and-c-mac-for-first-attempt-intubation-in-adults-undergoing-elective-surgery-100611327","NCT07239141","Two Video Laryngoscopes (Laringocel® and C-MAC®) for First-Attempt Intubation in Adults Undergoing Elective Surgery","Estimation of the Non-Inferiority of the Laringocel® Videolaryngoscope Compared With the C-MAC D-BLADE (Karl Storz®) for First-Attempt Intubation in Adult Patients Undergoing Elective Surgery","LARINGOCOL","Inclusion Criteria:\n\n* Patients 18 years of age or older\n* Patients scheduled for elective surgery under general anesthesia\n* Patients requiring single-lumen orotracheal intubation\n* Patients compliant with the anesthetic indication and standard preoperative fasting requirements\n\nExclusion Criteria:\n\n* Patients with an anticipated difficult airway (more than two anatomical risk factors for difficult airway)\n* Patient refusal to participate in the study via informed consent",{"count":589,"type":22},252,[25],"This study will test two video laryngoscopes that help doctors place a breathing tube during surgery. A breathing tube is needed for people who receive general anesthesia so they can breathe safely. Video laryngoscopes use a small camera to give a better view of the throat and vocal cords, which may help the tube go in on the first try.\n\nThe purpose of this research is to find out if a Colombian device called Laringocel® works as well as the widely used international device C-MAC D-Blade® (Karl Storz). If Laringocel® performs similarly, it could be a more affordable option for hospitals with limited resources.\n\n252 adults (126 in each group) who need elective surgery at Alma Máter Hospital de Antioquia (Medellín, Colombia) will take part. Each participant will be randomly assigned, like flipping a coin, to have their breathing tube placed with either Laringocel® or C-MAC D-Blade®. Only trained anesthesiologists will perform the procedure.\n\nThe study will look at:\n\nMain goal: how often the tube goes in correctly on the first attempt.\n\nOther goals: overall success within 3 attempts, how well the airway is seen, how long the intubation takes, how satisfied the doctor is with the device, and possible side effects such as sore throat, dental injury, or oral injury.\n\nParticipation will not change the usual care people receive during anesthesia. Both devices are already approved for clinical use. Risks are the same as with any standard intubation, and participants will be checked after surgery for any problems.\n\nBy comparing these two devices, researchers hope to learn if Laringocel® can provide safe and effective intubation at lower cost, improving access to advanced airway tools.",[28,593],"Intubation, Endotracheal",[595],"Videolaryngoscopy","2025-12-09",{"date":598,"type":41},"2025-12-11",{"date":600,"type":41},"2025-12-04",{"date":366,"type":22},{"name":603,"class":80},"Mario Zamudio",{"id":605,"slug":606,"hasResults":12,"nctId":607,"briefTitle":608,"officialTitle":609,"acronym":610,"eligibilityCriteria":611,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":612,"targetDuration":4,"studyType":23,"phases":613,"briefSummary":614,"conditions":615,"keywords":4,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":616,"lastUpdatePostDateStruct":617,"startDateStruct":619,"completionDateStruct":621,"leadSponsor":623,"locationsCount":49},"100593327","paratracheal-vs-cricoid-pressure-on-glittic-deformation-paraglide-100593327","NCT07004998","PARAtracheal vs CRIcoid Pressure on GLIttic DEformation (PARAGLIDE)","Comparison of Left Paratracheal Versus Cricoid Pressure on Glottic Visualization During Videolaryngoscopy: A Randomized Crossover Study","PARAGLIDE","Inclusion Criteria:\n\n* Age ≥ 18 years\n* Scheduled for elective surgery under general anesthesia requiring endotracheal intubation\n* ASA physical status I or II\n* Normal airway anatomy as assessed by the anesthesiologist (Mallampati I-II, no known or anticipated difficult airway)\n* Written informed consent obtained prior to inclusion\n\nExclusion Criteria:\n\n* History of difficult intubation or anticipated difficult airway\n* Known upper airway anatomical abnormalities (e.g., tumors, tracheal deviation, cervical spine instability)\n* BMI \\> 35 kg\u002Fm²\n* Gastroesophageal reflux disease or increased aspiration risk\n* Pregnancy\n* Emergency surgery\n* Allergy or contraindication to any anesthetic drugs used\n* Inability to provide informed consent",{"count":404,"type":22},[25],"This randomized crossover study evaluates the effects of left paratracheal pressure, cricoid pressure, and no pressure on glottic visualization during videolaryngoscopy in adult surgical patients. The primary endpoint is the Percentage of Glottic Opening (POGO) score assessed by blinded video review. Secondary endpoints include anatomical measures (glottic surface area, vertical and horizontal displacement of the glottic plane) and clinical outcomes (first-pass success, first-pass success without desaturation \\\u003C90%, intubation time, Intubation Difficulty Scale, hypoxemia, hemodynamic events, airway trauma, and postoperative sore throat or dysphonia). All outcomes are collected from routine anesthetic practice and video analysis, with no additional procedures.",[28],"2025-09-15",{"date":618,"type":41},"2025-09-19",{"date":620,"type":22},"2025-09",{"date":622,"type":22},"2025-12",{"name":624,"class":80},"University of Liege",{"id":626,"slug":627,"hasResults":12,"nctId":628,"briefTitle":629,"officialTitle":630,"acronym":4,"eligibilityCriteria":631,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":632,"targetDuration":4,"studyType":137,"phases":4,"briefSummary":634,"conditions":635,"keywords":638,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":643,"lastUpdatePostDateStruct":644,"startDateStruct":646,"completionDateStruct":648,"leadSponsor":650,"locationsCount":49},"100597393","comparison-of-intubation-using-video-laryngeal-mask-and-video-laryngoscope-in-elective-surgical-patients-100597393","NCT07057908","Comparison of Intubation Using Video Laryngeal Mask and Video Laryngoscope in Elective Surgical Patients","A Prospective Observational Study Comparing Tracheal Intubation Via Video Laryngeal Mask Airway and Video Laryngoscope in Adult Patients Undergoing Elective Surgery","Inclusion Criteria:\n\n* Adult patients aged 18 years and older\n* Patients scheduled for elective surgical procedures\n* Patients classified as ASA Physical Status I-III\n* Patients undergoing general anesthesia\n\nExclusion Criteria:\n\n* Patients younger than 18 years\n* Patients undergoing emergency surgery\n* Patients with difficult airway predictors, such as:\n\nMallampati score ≥ 3\n\nThyromental distance \\\u003C 6 cm\n\nMouth opening \\\u003C 3 cm\n\n* Patients with anatomical abnormalities or surgical history involving the oropharynx, larynx, or airway\n* Patients with conditions contraindicating head or neck manipulation (e.g., cervical instability, upper airway tumors)\n\nPregnant patients",{"count":633,"type":22},176,"This study compares two airway devices that are commonly used during elective surgery: the video laryngeal mask airway (VLM) and the video laryngoscope (VLS). Both are part of routine anesthesia practice. Our main focus is to measure how long intubation takes with each device and to see how successful the intubation is. The study does not involve any extra procedures or risks; everything will be carried out as part of normal patient care.",[28,64,636,595,637],"Elective Surgeries","Anaesthesia",[516,469,639,640,641,642],"SaCoVLM","Intubation Success Rate","Observational Study","Elective Surgical Patients","2025-08-28",{"date":645,"type":41},"2025-09-05",{"date":647,"type":22},"2025-09-01",{"date":649,"type":22},"2026-03-02",{"name":651,"class":80},"Samsun University",{"id":653,"slug":654,"hasResults":12,"nctId":655,"briefTitle":656,"officialTitle":656,"acronym":4,"eligibilityCriteria":657,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":658,"targetDuration":4,"studyType":137,"phases":4,"briefSummary":660,"conditions":661,"keywords":663,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":665,"lastUpdatePostDateStruct":666,"startDateStruct":668,"completionDateStruct":670,"leadSponsor":672,"locationsCount":49},"100601750","external-validation-of-the-mascan-score-for-the-classification-of-difficult-mask-ventilation-100601750","NCT07114549","External Validation of the MASCAN Score for the Classification of Difficult Mask Ventilation","Inclusion Criteria:\n\n* Patients who are scheduled for surgery with general anesthesia and require facemask ventilation and tracheal intubation after induction of anesthesia\n* Patients aged 18 years or older\n* Provided informed consent\n\nExclusion Criteria:\n\n* Pregnant or breastfeeding woman\n* Required rapid sequence induction or other contraindications for facemask ventilation\n* Planned awake tracheal intubation\n* No consent given",{"count":659,"type":22},926,"The MASCAN Score is a prospectively developed objective classification for difficult facemask ventilation. This prospective observational study aims to externally validate the MASCAN score in patients undergoing general anaesthesia for surgical procedures and to determine the influence of different approaches and techniques, such as the timing of neuromuscular blocking agents and manual versus controlled facemask ventilation. A secondary aim is to determine the diagnostic value of visual assessments of the capnography curve. Another secondary aim of the study is to compare the assessment of the first attempt success during tracheal intubation between the airway operator and an independent observer.",[28,63,662],"Mask Ventilation",[30,664],"Mask ventilation","2025-08-17",{"date":667,"type":41},"2025-08-21",{"date":669,"type":41},"2025-08-08",{"date":671,"type":22},"2026-01",{"name":673,"class":80},"Universitätsklinikum Hamburg-Eppendorf"]