[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"airway-obstruction-postoperative\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:airway-obstruction-postoperative":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,49],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":30,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":48},"100615030","endotracheal-tube-suctioning-versus-no-suctioning-during-emergence-from-general-anesthesia-100615030",false,"NCT07287293","Endotracheal Tube Suctioning Versus No Suctioning During Emergence From General Anesthesia","Comparison of Endotracheal Tube Suctioning Versus No Suctioning During Emergence From General Anesthesia With Endotracheal Intubation: A Randomized, Single-Blind Study","Inclusion Criteria:\n\n* Adults aged 18-90 years with American Society of Anesthesiologists (ASA) physical status I-III.\n* Scheduled for elective surgery under general anesthesia requiring endotracheal intubation.\n* Planned tracheal extubation in the operating room at the end of surgery.\n\nExclusion Criteria:\n\n* Inability to provide informed consent or the presence of a significant language barrier that prevents effective communication with the clinical team.\n* Known diagnosis of obstructive sleep apnea (OSA), active pneumonia, or chronic pulmonary disease (e.g., chronic obstructive pulmonary disease, restrictive lung disease).\n* Body mass index (BMI) \\>35 kg\u002Fm².\n* Pregnancy or increased aspiration risk (e.g., full stomach).\n* Scheduled for maxillofacial, head and neck, or airway surgery.\n* Anticipated surgical duration \\>3.5 hours.\n* Anticipated difficult airway, defined as the presence of ≥2 predictors of difficult mask ventilation (DMV) based on Langeron et al., or a documented history of difficult intubation.","ALL","18 Years",{"count":19,"type":20},408,"ESTIMATED","INTERVENTIONAL",[23],"NA","The goal of this study is to determine whether omitting tracheal suctioning immediately prior to extubation is non-inferior to routine tracheal suctioning with respect to early postoperative oxygenation among adult surgical patients (aged 18-90 years, American Society of Anesthesiologists \\[ASA\\] physical status I-III) undergoing elective surgery under general anesthesia with endotracheal intubation.\n\nThe study addresses the following questions:\n\n* Primary outcome (non-inferiority):\n* Is the risk of postoperative desaturation (oxygen saturation \\[SpO₂\\] \\\u003C92% within 60 minutes after extubation) in the no-suction group not worse than in the routine-suction group by more than 10 percentage points?\n* Secondary outcomes (superiority):\n* Does omitting tracheal suctioning reduce postoperative cough severity and sore throat?\n* Does omitting tracheal suctioning avoid increasing extubation-related adverse events?\n\nParticipants will be randomly assigned (1:1) to one of two groups:\n\n* Routine suctioning (SUC): Endotracheal suctioning plus oropharyngeal suctioning immediately before extubation\n* No suctioning (NON-SUC): Oropharyngeal suctioning only, without endotracheal suctioning\n\nAll participants will receive standard anesthetic care and postoperative monitoring in the post-anesthesia care unit (PACU) for 60 minutes. Follow-up for airway symptoms and patient satisfaction will be conducted at 24 hours after surgery.",[26,27,28,29],"Hypoxia","Airway Obstruction, Postoperative","Sore Throat","Cough, Postoperative",[31,32,33,26,34,35],"Airway Management","Suctioning","Emergence from Anesthesia","Endotracheal Intubation","Postoperative Complications","RECRUITING","2026-01-09",{"date":39,"type":40},"2026-01-12","ACTUAL",{"date":42,"type":40},"2026-01-05",{"date":44,"type":20},"2027-03-31",{"name":46,"class":47},"Mahidol University","OTHER",1,{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":55,"eligibilityCriteria":56,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":57,"enrollmentInfo":58,"targetDuration":4,"studyType":21,"phases":60,"briefSummary":61,"conditions":62,"keywords":66,"overallStatus":77,"whyStopped":4,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":48},"100596247","peri-operative-bipap-to-prevent-tracheostomy-in-high-risk-bilateral-vocal-cord-paralysis-bvcp-100596247","NCT07042971","Peri-operative BiPAP to Prevent Tracheostomy in High-Risk Bilateral Vocal-Cord Paralysis (BVCP)","A Multicenter, Randomized Controlled Trial of Pre-operative BiPAP Training and Post-extubation BiPAP Support to Reduce Peri-operative Tracheostomy or Re-intubation in Patients at High Risk for Bilateral Vocal-Cord Paralysis","BVCP-BiPAP","Inclusion Criteria:\n\n* Age 18 - 80 years.\n* Scheduled for thyroidectomy or other neck surgery under general anesthesia.\n* High risk of bilateral vocal-cord paralysis (BVCP) defined by at least ONE of:\n\n  * Pre-operative flexible laryngoscopy showing fixed vocal cords at midline or paramedian position, or glottic gap ≤ 3 mm; OR\n  * Presence of ≥ 2 high-risk factors:\n\n    * Planned bilateral central plus lateral neck dissection\n    * Re-operative bilateral neck surgery or dense scarring\n    * Tumor involving both recurrent laryngeal nerves or crico-arytenoid joints\n    * Severe obstructive sleep apnea (AHI ≥ 30 events\u002Fhour)\n    * Body-mass index (BMI) ≥ 30 kg\u002Fm²\n* Able to tolerate and give informed consent for BiPAP mask use.\n\nExclusion Criteria:\n\n* Emergency surgery or need for immediate tracheostomy.\n* Existing tracheostomy or home ventilator dependence.\n* Inability to protect airway (e.g., Glasgow Coma Scale \\\u003C 13).\n* Craniofacial anomaly or skin condition precluding mask seal.\n* Pregnancy or breastfeeding.\n* Participation in another interventional trial that could interfere with study endpoints.","80 Years",{"count":59,"type":20},204,[23],"Why: After thyroid or neck surgery, some patients can lose movement of both vocal cords (bilateral vocal-cord paralysis, BVCP). This can make breathing difficult and often leads to an emergency or preventive tracheostomy (\"wind-pipe\") surgery.\n\nWhat: This study will test two simple ways to avoid a tracheostomy:\n\nPre-operative BiPAP sleep training - patients practice sleeping with a non-invasive BiPAP breathing machine for seven nights before surgery so they become comfortable with the mask and pressures.\n\nImmediate post-extubation BiPAP support - the same BiPAP machine is started as soon as the breathing tube is removed in the operating room or recovery area.\n\nHow: Adults (18-80 years) who already have, or are at high risk of getting, BVCP will be randomly assigned to one of four groups in a 2 × 2 design:\n\n• Group 1: training + post-op BiPAP • Group 2: training only • Group 3: post-op BiPAP only • Group 4: standard care (no planned BiPAP).\n\nMain goal: To find out whether either or both BiPAP strategies reduce the need for tracheostomy or re-intubation during the first 7 days after surgery.\n\nWhat participants do: Eligible patients will undergo routine surgery plus the assigned BiPAP plan. Breathing events, comfort, hospital stay, and voice quality will be recorded up to 6 months.\n\nPotential benefit\u002Frisk: BiPAP is non-invasive and already FDA-cleared for home and hospital use, but some people may feel mask discomfort or air leaks. Trained staff will adjust settings and stop BiPAP if serious problems occur.",[63,27,64,65],"Vocal Cord Paralysis, Bilateral","Thyroid Neoplasms","Sleep Apnea, Obstructive",[67,68,69,70,71,72,73,74,75,76],"BiPAP","Non-invasive Ventilation","Continuous Positive Airway Pressure","Peri-operative Airway Management","Tracheostomy Avoidance","Thyroidectomy","Neck Surgery","Glottic Stenosis","Pre-operative Sleep Training","Voice Handicap Index","NOT_YET_RECRUITING","2025-06-27",{"date":80,"type":40},"2025-06-29",{"date":82,"type":20},"2025-07-01",{"date":84,"type":20},"2029-12-31",{"name":86,"class":47},"Fujian Medical University"]