[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"airway-obstruction\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:airway-obstruction":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,52,86,121],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":32,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":41,"lastUpdatePostDateStruct":42,"startDateStruct":45,"completionDateStruct":47,"leadSponsor":49,"locationsCount":4},"100642485","perioperative-respiratory-adverse-events-in-cleft-lip-and-palate-surgery-incidence-risk-factors-and-clinical-scoring-100642485",false,"NCT07651904","Perioperative Respiratory Adverse Events in Cleft Lip and Palate Surgery: Incidence, Risk Factors, and Clinical Scoring","Prospective Assessment of Perioperative Respiratory Adverse Events in Pediatric Patients Undergoing Cleft Lip and Palate Surgery: Predictive Risk Factors and the Role of Clinical Airway Scores","Inclusion Criteria:\n\n* Age 0-3 years (infants and toddlers)\n* Scheduled for elective cleft lip and\u002For palate repair surgery\n* General anesthesia planned\n* Written parental\u002Fguardian informed consent obtained\n\nExclusion Criteria:\n\n* Pre-existing respiratory failure or active tracheostomy\n* Emergency surgical procedures\n* Inability to obtain parental\u002Fguardian consent","ALL","0 Years","3 Years",{"count":20,"type":21},150,"ESTIMATED","OBSERVATIONAL","Cleft lip and palate surgeries present unique anesthetic challenges due to shared airway access with the surgical field, frequent anatomical abnormalities, and a predominantly infant and toddler population. These factors substantially increase the risk of perioperative respiratory adverse events (PRAEs), including laryngospasm, bronchospasm, desaturation, post-extubation stridor, and unanticipated re-intubation.\n\nThis prospective single-center observational cohort study aims to determine the true incidence of PRAEs in pediatric patients undergoing elective cleft lip and\u002For palate repair under general anesthesia, and to identify independent predictive risk factors using standardized airway assessment tools including the Han Mask Ventilation Score and the Intubation Difficulty Score (IDS). No interventions beyond routine clinical practice will be applied. All airway management decisions will remain at the discretion of the attending anesthesiologist.",[25,26,27,28,29,30,31],"Cleft Palate","Cleft Lip","Laryngospasm","Bronchospasm","Airway Obstruction","Postoperative Complications","Difficult Intubation",[33,34,35,36,37,38,39],"cleft lip","cleft palate","pediatric anesthesia","perioperative respiratory adverse events","Han mask ventilation score","micrognathia","intubation difficulty score","NOT_YET_RECRUITING","2026-06-13",{"date":43,"type":44},"2026-06-16","ACTUAL",{"date":46,"type":21},"2026-06-27",{"date":48,"type":21},"2027-12-30",{"name":50,"class":51},"Marmara University Pendik Training and Research Hospital","OTHER",{"id":53,"slug":54,"hasResults":11,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":4,"eligibilityCriteria":58,"healthyVolunteers":59,"sex":16,"minAge":60,"maxAge":4,"enrollmentInfo":61,"targetDuration":4,"studyType":63,"phases":64,"briefSummary":66,"conditions":67,"keywords":70,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":85},"100632597","supplemental-oxygen-and-oxygen-desaturations-in-colonoscopies-100632597","NCT07515755","Supplemental Oxygen and Oxygen Desaturations in Colonoscopies","Evaluation of Oxygen Desaturation and Apnea Events With Supplemental Oxygen During Procedural Sedation in Colonoscopies","Inclusion Criteria:\n\n* Adult patient\n* No life threatening conditions\n* Undergoing colonoscopy procedures and receiving procedural sedation at the University of Utah Health clinic in South Jordan, Utah.\n\nExclusion Criteria:\n\n* Inability\u002Frefusal of subject to provide informed consent.\n* Less than 18 years of age.\n* Standard colonoscopy exclusion criteria used at the GI lab at the University of Utah.\n* Patients known or suspected to be pregnant.\n* Patients with an ASA physical status of IV (A patient with severe systemic disease that is a constant threat to life) or V (A moribund patient who is not expected to survive without the operation).\n* Patients known to have acute respiratory distress syndrome, severe COPD, or cardiovascular disease.\n* If their oxygen saturation measured by pulse oximetry (SpO2) is below 93% while breathing room air prior to the procedure.\n* Patients with severe medical condition(s) that in the view of the acting physician prohibits participation in the study.",true,"18 Years",{"count":62,"type":21},280,"INTERVENTIONAL",[65],"NA","This study will compare apnea and oxygen desaturation events among various methods of supplemental oxygen delivery during procedural sedation in colonoscopy patients. The goals of the study are to track apnea (10 or more seconds without respiration) and oxygen desaturation (hemoglobin oxygen saturation less than 90%) events in colonoscopy patients receiving one of three different methods of supplemental oxygen administration. The first method is standard-of-care continuous flow oxygen therapy, where a constant flow of oxygen is administered through a nasal cannula or oxygen mask. The second method is synchronized flow oxygen therapy. This is a delivery method implemented in an FDA-cleared medical device (Sovant, Dynasthetics LLC) which delivers variable-volume oxygen pulses only as the patient inhales. The delivered oxygen pulses are commensurate to the set flow rate and the patient's respiratory rate. The third method is continuous positive airway pressure therapy (CPAP), where non-invasive pressure support is given to the patient's airway to help keep their airway open. The hypothesis being tested is that synchronized flow delivery and CPAP therapy will demonstrate reductions in apnea and oxygen desaturation events compared to traditional continuous flow oxygen therapy.",[68,69,29],"Oxygen Desaturation","Apnea (Central and Obstructive)",[71,72,73,74,75],"CPAP","apnea","desaturation","sedation","colonoscopy","2026-03-31",{"date":78,"type":44},"2026-04-07",{"date":80,"type":21},"2026-05-18",{"date":82,"type":21},"2026-12-31",{"name":84,"class":51},"University of Utah",1,{"id":87,"slug":88,"hasResults":11,"nctId":89,"briefTitle":90,"officialTitle":91,"acronym":4,"eligibilityCriteria":92,"healthyVolunteers":11,"sex":16,"minAge":60,"maxAge":4,"enrollmentInfo":93,"targetDuration":4,"studyType":63,"phases":95,"briefSummary":96,"conditions":97,"keywords":4,"overallStatus":111,"whyStopped":4,"lastUpdateSubmitDate":112,"lastUpdatePostDateStruct":113,"startDateStruct":115,"completionDateStruct":117,"leadSponsor":119,"locationsCount":85},"100557458","clinical-utility-of-portable-dynamic-chest-x-ray-ddr-in-the-icu-100557458","NCT06538376","Clinical Utility of Portable Dynamic Chest X Ray (DDR) in the ICU","Clinical Utility of Portable Dynamic Chest X-Ray (DDR) in the ICU: Clinical Trial to Demonstrate the Feasibility of Deploying DDR Technology in the ICU - A Study to Prove Its Increased Diagnostic Value","Inclusion Criteria: Participants must meet all the following inclusion criteria to participate in this study:\n\n* Adults (at least 18 years of age) including both intubated\u002Fventilated and non-intubated patients\n* Likely to have pathology related to either, abnormal diaphragmatic excursion and lung aeration, pulmonary perfusion, increased lung water content or all the above, as well as for cricopharyngeal dysfunction\u002Fswallowing difficulties at risk for aspiration.\n* The subject or a legally authorized representative has provided written informed consent.\n\nExclusion Criteria: Candidates meeting any of the exclusion criteria at baseline will be excluded from study participation. These criteria are:\n\n* Special populations, including women with known pregnancy, prisoners, or institutionalized individuals\n* Patients where additional radiation is clinically contraindicated\n* Care team does not provide assent for approaching patient\u002Fsurrogate\n* For women of child-bearing potential, defined as premenopausal women, a pregnancy test will be administered to determine pregnancy status and confirm eligibility for the study. A pregnancy test will NOT be administered to women who are post-menopausal or have documentation of surgical sterilization.",{"count":94,"type":21},230,[65],"Dynamic digital radiography (DDR) is a new advanced version of chest radiography that captures dynamic images at a rate of 15 frames per second. It is coupled with an analytical software that allows it to provide more advanced measures of lung motion, ventilation, and perfusion compared to traditional chest radiography. While implementation of DDR fixed machines are beginning elsewhere in the US, this trial involves the first applications of an FDA-approved portable DDR machine, for use at the bedside in the ICU.\n\nThe goal of this clinical trial is to determine the feasibility and safety of portable DDR technology in the ICU, as well as to evaluate the improved clinical diagnostic value of the portable DDR system over current standards of care.\n\nParticipants will receive one to three sets of DDR images, which will then be compared to their clinical gold standard exams (such as chest x-rays, CTs, or VQ scans) to assess and improve the precision and accuracy of measurements such as diaphragmatic motion, lung movement, and perfusion.",[98,99,100,101,102,29,103,104,105,106,107,108,109,110],"Pulmonary Edema","Pneumonia","Atelectasis","Pleural Effusion","Acute Rejection of Lung Transplant (Disorder)","Rib Fractures","Acute Copd Exacerbation","Asthma COPD","Pulmonary Embolism","Hemothorax","Pneumothorax","Mesothelioma","Diaphragmatic Paralysis","RECRUITING","2025-10-28",{"date":114,"type":44},"2025-10-29",{"date":116,"type":44},"2023-12-12",{"date":118,"type":21},"2027-11",{"name":120,"class":51},"Brigham and Women's Hospital",{"id":122,"slug":123,"hasResults":11,"nctId":124,"briefTitle":125,"officialTitle":126,"acronym":4,"eligibilityCriteria":127,"healthyVolunteers":11,"sex":16,"minAge":60,"maxAge":4,"enrollmentInfo":128,"targetDuration":4,"studyType":63,"phases":130,"briefSummary":131,"conditions":132,"keywords":4,"overallStatus":111,"whyStopped":4,"lastUpdateSubmitDate":133,"lastUpdatePostDateStruct":134,"startDateStruct":136,"completionDateStruct":138,"leadSponsor":140,"locationsCount":85},"100514130","the-efficacy-of-distal-pharyngeal-airway-for-oxygenation-during-tee-100514130","NCT05974488","The Efficacy of Distal Pharyngeal Airway for Oxygenation During TEE","The Efficacy of Distal Pharyngeal Airway in Enhancing Oxygenation During Transesophageal Echocardiography (TEE) in Patients Sedated With Propofol","Inclusion Criteria:\n\n* Age \\> or = 18 years old\n* Patients willing to participate and provide an informed consent\n* Patients scheduled to undergo an elective TEE procedure.\n\nExclusion Criteria:\n\n* Patients with history of uncontrolled gastroesophageal reflux disease\n* Patients with anatomical airway obstruction\n* Have any condition that, in the opinion of the investigator, would compromise the well-being of the patient or the study or prevent the patient from meeting or performing study requirements",{"count":129,"type":21},50,[65],"The purpose of this study is to investigate the effect of using the McMurray Enhanced Airway (MEA) which is a flexible extended-length distal pharyngeal airway on improving oxygen delivery compared to standard nasal cannula.",[29],"2025-09-30",{"date":135,"type":44},"2025-10-06",{"date":137,"type":44},"2023-11-30",{"date":139,"type":21},"2026-10-01",{"name":141,"class":51},"University of Miami"]