[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"airway-stenosis\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:airway-stenosis":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,45],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100626014","flow-controlled-versus-volume-controlled-ventilation-during-balloon-dilatation-under-direct-laryngoscopy-100626014",false,"NCT07430124","Flow-Controlled Versus Volume-Controlled Ventilation During Balloon Dilatation Under Direct Laryngoscopy","Comparison of Flow-Controlled and Volume-Controlled Ventilation During Balloon Dilatation Under Direct Laryngoscopy: A Prospective Randomized Trial","Inclusion Criteria:\n\n* Age between 18 and 65 years\n* ASA physical status I-III\n\nExclusion Criteria:\n\n* Age \\\u003C 18 years or \\> 65 years\n* Known or previously diagnosed pulmonary disease\n* Patients with severe preoperative pulmonary function impairment (e.g., FEV₁ \\\u003C 50% predicted, severe restrictive or obstructive pathology)\n* Patients with markedly altered lung anatomy or function due to prior major thoracic surgery\n* Patients who were dependent on supplemental oxygen therapy in the preoperative period\n* ASA physical status IV or higher\n* Refusal or inability to provide informed consent","ALL","18 Years","65 Years",{"count":20,"type":21},40,"ESTIMATED","INTERVENTIONAL",[24],"NA","This prospective trial aims to compare the effects of flow-controlled ventilation (FCV) and volume-controlled ventilation (VCV) on airway pressures and oxygenation in adult patients undergoing balloon dilatation under direct laryngoscopy. Airway procedures performed under general anesthesia are associated with unique respiratory mechanics and limited ventilation conditions, making the choice of an optimal ventilation strategy particularly important.\n\nAdult patients aged 18-65 years with American Society of Anesthesiologists (ASA) physical status I-III will be allocated to receive either FCV or VCV during surgery. Ventilatory parameters, airway pressures, pulmonary compliance, and arterial blood gas values will be recorded at predefined intraoperative time points. The primary outcome is the PaO₂ measured 20 minutes under an FiO₂ of 0.8-1.0 after starting the ventilation under general anesthesia, reflecting early intraoperative oxygenation under stable conditions.\n\nBy providing comparative data on respiratory mechanics and oxygenation, this study aims to contribute to the identification of lung-protective ventilation strategies in patients undergoing balloon dilatation under direct laryngoscopy.",[27,28],"Airway Stenosis","Upper Airway Obstruction",[30,31,32],"Direct Laryngoscopy","Flow-Controlled Ventilation","Volume-Controlled Ventilation","RECRUITING","2026-02-24",{"date":36,"type":37},"2026-02-25","ACTUAL",{"date":34,"type":37},{"date":40,"type":21},"2026-08-20",{"name":42,"class":43},"Ankara Etlik City Hospital","OTHER_GOV",1,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":4,"eligibilityCriteria":51,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":52,"targetDuration":4,"studyType":22,"phases":54,"briefSummary":55,"conditions":56,"keywords":4,"overallStatus":57,"whyStopped":4,"lastUpdateSubmitDate":58,"lastUpdatePostDateStruct":59,"startDateStruct":61,"completionDateStruct":63,"leadSponsor":65,"locationsCount":4},"100580103","the-efficacy-and-safety-of-robotic-bronchoscopy-system-assisted-stent-placement-in-patients-with-malignant-central-airway-stenosis-100580103","NCT06832943","The Efficacy and Safety of Robotic Bronchoscopy System-Assisted Stent Placement in Patients with Malignant Central Airway Stenosis","A Prospective Multicenter Single-Arm Trial Evaluating the Efficacy and Safety of Robotic Bronchoscopy System-Assisted Stent Placement in Patients with Malignant Central Airway Stenosis","Inclusion Criteria:\n\n* Patients are eligible only if they fulfill all of the following criteria:\n\n  1. Age ≥ 18 years, regardless of gender;\n  2. Patients voluntarily consent to airway stent implantation and meet the requirements for airway stent implantation under general anesthesia;\n  3. Confirmed as having malignant central airway stenosis through bronchoscopy and being ineligible for surgery or refusing surgery, and in need of airway stent implantation.\n\nPatients should be able to understand the purpose of the trial, demonstrate good compliance with the examinations and follow-ups, and voluntarily participate in the clinical trial and sign the informed consent form.\n\nExclusion Criteria:\n\n* Patients fulfilling any of the following criteria will be excluded from this study:\n\n  1. Severe dysfunction of the heart, lungs, liver, or kidneys, intolerant of bronchoscopic treatment;\n  2. Apparent coagulation dysfunctions;\n  3. Pregnant or lactating women, or participants with a pregnancy plan during the study period;\n  4. Patients with implanted cardiac pacemakers, implanted defibrillators, or other active implants;\n  5. Participants allergic to photosensitizers or anesthetics, or with a history of multiple severe allergies or hereditary allergies;\n  6. Participants who have participated in or are currently participating in drug clinical trials within the past 3 months, or in other medical device clinical trials within the past 30 days; Other circumstances that the investigator considers inappropriate for participation in this clinical trial.",{"count":53,"type":21},30,[24],"The primary aim of this research is to assess the efficacy and safety of the bronchial navigation positioning equipment in assisting stent implantation for malignant central airway stenosis while guaranteeing the safety of the participants and the scientificity of the clinical trial.",[27],"NOT_YET_RECRUITING","2025-02-12",{"date":60,"type":37},"2025-02-18",{"date":62,"type":21},"2025-02-15",{"date":64,"type":21},"2025-12-31",{"name":66,"class":67},"Guangzhou Medical University","OTHER"]