[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"aki-acute-kidney-injury-due-to-trauma\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:aki-acute-kidney-injury-due-to-trauma":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,45,71],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":29,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":4},"100632878","acute-kidney-injury-and-ultra-endurance-running-100632878",false,"NCT07519408","Acute Kidney Injury and Ultra-endurance Running","The Incidence and Severity of Acute Kidney Injury in Ultrarunners Competing in the Western States Endurance Run","Inclusion Criteria:\n\n* Running in the Western States Endurance Run in either 2026, 2027 or 2028\n* No contraindications to exercise as indicated by the Physical Activity Readiness Questionnaire (PAR-Q+) as prepared by the American College of Sports Medicine (ACSM)\n* Not currently taking medicine or experiencing illness that may influence the cardiovascular or neuromuscular system\n* Age ≥18 and ≤ 50 years old and injury free (skeletal muscle) for \\> 3 months\n\nExclusion Criteria:\n\n* Minors (under 18)\n* Adults who are unable to consent (impaired decision-making capacity)\n* Prisoners\n* Pregnant Women\n* Individuals with known kidney disease, or are on any medication that specifically effects kidney function (e.g., diuretics)",true,"ALL","18 Years","50 Years",{"count":21,"type":22},30,"ESTIMATED","INTERVENTIONAL",[25],"NA","This study aims to understand how participating in the Western States Endurance Run (WSER), a 100-mile ultramarathon, affects kidney health. Long, strenuous exercise in hot conditions can temporarily strain the kidneys, especially when combined with dehydration, muscle breakdown, and the use of common pain-relief medications such as ibuprofen. Although kidney stress has been reported in endurance sports, no study has examined it directly in runners during the WSER using newer, more sensitive urine markers of kidney injury. Runners who volunteer will complete brief assessments before and after the race. These include providing a urine sample, a small finger-prick blood sample, a body-weight measurement, and answering a short questionnaire about pain-medication use. During the race, participants will wear a global positioning system (GPS) watch and heart-rate strap to monitor effort. Each assessment takes about 15 minutes, and no follow-up is required. Findings from this study will help determine how often kidney stress occurs in this event and what factors may contribute to it, ultimately supporting safer training and medical practices for ultramarathon athletes.",[28],"AKI (Acute Kidney Injury) Due to Trauma",[30,31,32],"ultra-endurance","bicarbonate","AKI","NOT_YET_RECRUITING","2026-04-07",{"date":36,"type":37},"2026-04-09","ACTUAL",{"date":39,"type":22},"2026-06-27",{"date":41,"type":22},"2028-12-01",{"name":43,"class":44},"Arizona State University","OTHER",{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":51,"eligibilityCriteria":52,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":53,"targetDuration":4,"studyType":55,"phases":4,"briefSummary":56,"conditions":57,"keywords":4,"overallStatus":60,"whyStopped":4,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":70},"100586567","renal-perfusion-and-the-development-of-aki-following-traumatic-injury-100586567","NCT06917053","Renal Perfusion and the Development of AKI Following Traumatic Injury","Renal Perfusion and the Development of AKI Following Traumatic Injury - A Longitudinal Observational Cohort Study","PERTAKI","Inclusion Criteria:\n\n* Age \\> 18 years\n* Within 24 hours of ICU admission following traumatic injury\n* Received any blood products during initial resuscitation\n* Lactate \\> 2 mmol\u002Fl at any stage prior to study enrolment\n\nExclusion Criteria:\n\n* Known intolerance to Sonovue or any other ultrasound contrast agent\n* Patients with un-survivable injuries \u002F not expected to survive 24 hours in whom the intent of treatment is palliative\n* Known CKD 4 or end stage renal failure\n* Pregnancy",{"count":54,"type":22},20,"OBSERVATIONAL","Acute kidney injury (AKI) is a complication of traumatic haemorrhagic shock (THS) and together these conditions increase mortality risk. Although septic shock patients who develop severe AKI are known to develop hypoperfusion of the renal cortex, little is known regarding intra-renal perfusion changes in THS. The aim of the current study is to investigate the effects of THS on renal microcirculatory perfusion.",[58,28,59],"Traumatic Haemorrhagic Shock","AKI - Acute Kidney Injury","RECRUITING","2025-04-01",{"date":63,"type":37},"2025-04-08",{"date":65,"type":37},"2024-04-13",{"date":67,"type":22},"2026-07",{"name":69,"class":44},"King's College Hospital NHS Trust",1,{"id":72,"slug":73,"hasResults":11,"nctId":74,"briefTitle":75,"officialTitle":75,"acronym":76,"eligibilityCriteria":77,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":78,"enrollmentInfo":79,"targetDuration":4,"studyType":23,"phases":81,"briefSummary":83,"conditions":84,"keywords":4,"overallStatus":60,"whyStopped":4,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":70},"100383959","phase-4-single-center-prospective-study-to-investigate-the-difference-in-the-incidence-of-contrast-induced-nephropathy-in-high-risk-patients-with-the-use-of-the-dye-vert-plus-system-100383959","NCT04279457","Single-Center Prospective Study to Investigate the Difference in the Incidence of Contrast-Induced Nephropathy in High-Risk Patients With the Use of the Dye-Vert Plus System","Dye-Vert Plus","Inclusion Criteria:\n\n* Inclusion criteria:\n\n  1. 18 years of age or older\n  2. Scheduled to undergo CAG and\u002For PCI\n  3. Baseline estimated glomerular filtration rate (eGFR) of ≥20 and ≤60 mL\u002F min\u002F1.73 m2\n  4. Serum creatinine \\> 1.5mg\u002Fdl\n  5. Obtaining a Cardiac catheterization.\n  6. HTN\u002FDiabetes\n  7. Inpatient and outpatient\n\nExclusion Criteria:\n\n* Exclusion criteria:\n\n  1. 91 years of age or older\n  2. Serum creatinine \\\u003C 1.5mg\u002Fdl\n  3. eGFR \\> 60ml\u002Fmin\n  4. Pregnancy\n  5. Dialysis\n  6. Dye Allergy","90 Years",{"count":80,"type":22},1802,[82],"PHASE4","Coronary angiography (CAG) for diagnostic or therapeutic purposes such as percutaneous coronary intervention (PCI) is one of the common procedures which require the use of intravenous contrast media. The reported incidence of contrast induced nephropathy (CIN) in high-risk patients following CAG varies from 10% to 30%. The high rate of CIN in post-PCI patients could be related either to the patient (advanced age, previous CKD, diabetes, dehydration, and concomitant use of other nephrotoxic drugs) or procedure related (intra-arterial route of administration, use of high osmolar contrast media, repeated exposure to contrast within 48 hours, volume of contrast used). Several strategies to prevent or treat CIN have been developed, including hydration, N-acetyl-cysteine, statins, ascorbic acid, bicarbonate, aminophylline, forced diuresis, renal replacement therapy, and choice of low-osmolarity or alternative agents, but one of the most obvious means is to minimize contrast volume. The DyeVert plus Contrast Reduction System, is designed to lower the amount of contrast dye the kidneys are exposed to during a procedure. Because the amount of contrast dye is precisely controlled. The purpose of this prospective study is to understand how the monitoring system of Dye-Vert Plus will impact Acute Kidney Injuries rates in high-risk patients undergoing cardiac catheterization when used in conjunction with a standardized hydration policy.",[28],"2020-02-20",{"date":87,"type":37},"2020-02-24",{"date":89,"type":37},"2020-02-03",{"date":91,"type":22},"2022-02-03",{"name":93,"class":44},"CAMC Health System"]