[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"akut-kidney-injury\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:akut-kidney-injury":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,44],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100574880","the-role-of-furosemide-stress-test-in-the-intensive-care-clinic-100574880",false,"NCT06765031","The Role of Furosemide Stress Test in the Intensive Care Clinic","The Role of Furosemide Stress Test in Predicting Acute Kidney Injury Progression and Need for Renal Replacement Therapy in Patients Followed in the Intensive Care Clinic","Inclusion Criteria:\n\n1. Those who meet KDIGO AKI stage 1 and stage 2 criteria in the first 24 hours\n2. Those with sufficient fluid volume (CVP≥6 cmH20)\n3. Female and male patients over the age of 18 will be included in the study\n\nExclusion Criteria:\n\n1. Pregnant patients\n2. Hospitalization due to intoxication\n3. Liver or kidney transplant\n4. Glomerular filtration rate below 30 ml\u002Fmin\u002F1.73m2\n5. Active bleeding\n6. Patients with obstructive uropathy\n7. Patients in need of urgent RRT (K≥6.6 meq\u002FL, pH\\\u003C7.15, pulmonary edema due to fluid overload, uremic complications)\n8. Patients evaluated as KDIGO AKI stage 3\n9. Patients who have received RRT in the last 30 days\n10. Patients with CKD diagnosis\n11. Patients with pulmonary embolism\n12. Hypoalbuminemia≥2.5 g\u002Fdl,\n13. Patients receiving cephalosporin treatment will be excluded from the sample.","ALL","18 Years",{"count":19,"type":20},140,"ESTIMATED","INTERVENTIONAL",[23],"NA","AKI causes high mortality and morbidity, especially in critically ill patients, and prolongs the patient's stay in the intensive care unit. Due to the high morbidity and mortality associated with AKI, many researchers are studying several new biomarkers for earlier detection of AKI, determination of etiologies, and prediction of outcomes. However, the use of these new biomarkers may be limited due to reimbursement issues. In addition to the therapeutic role of furosemide in fluid balance, blood pressure control, and hypercalcemia management, Chawla et al. recommend the furosemide stress test (FST) as a tool to predict AKI progression. Designing a test that predicts the probability of AKI progression will help us make better decisions regarding the optimal timing of RRT initiation. In this study, we aimed to evaluate the feasibility of using the FST test in determining the progression of AKI in patients hospitalized in the intensive care unit and the need for RRT using the noninvasive procedure furosemide stress test.",[26],"Akut Kidney Injury",[28,29,30],"akut kidney injury","furosemide stres test","continuous renal replasman terapy","RECRUITING","2026-01-08",{"date":34,"type":35},"2026-01-12","ACTUAL",{"date":37,"type":35},"2024-11-01",{"date":39,"type":20},"2026-03-31",{"name":41,"class":42},"Gulhane Training and Research Hospital","OTHER_GOV",1,{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":4,"eligibilityCriteria":50,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":51,"targetDuration":53,"studyType":54,"phases":4,"briefSummary":55,"conditions":56,"keywords":58,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":43},"100592576","the-role-of-renal-resistive-index-ri-in-predicting-acute-kidney-injury-progression-in-intensive-care-clinic-100592576","NCT06995222","The Role of Renal Resistive Index (RI) in Predicting Acute Kidney Injury Progression in Intensive Care Clinic","The Role of Renal Resistive Index (RI) in Predicting Acute Kidney Injury Progression and Need for Renal Replacement Therapy in Patients Followed in the Intensive Care Clinic","Inclusion Criteria:\n\n1. Being over 18 years of age\n2. Having KDIGO stage 1 or stage 2 acute kidney injury within the first 24 hours of admission\n\nExclusion Criteria:\n\n* 1\\. Patients who did not provide a consent form for participation in the study 2. Patients under 18 years of age 3. Pregnant women 4. Patients with postrenal acute kidney injury 5. Patients 24 hours after the diagnosis of acute kidney injury 6. Patients with acute kidney injury in the recovery period 7. Patients who were evaluated as KDIGO ABH stage 3 during hospitalization 8. Patients with a known history of renal artery stenosis 9. Patients with a diagnosis of cardiac arrhythmia 10. Patients with a diagnosis of chronic kidney disease and a glomerular filtration rate below 30 ml\u002Fmin\u002F1.73m2 11. Patients with intra-abdominal pressure above 20 mmHg 12. Patients with a hospitalization period of less than 24 hours",{"count":52,"type":20},120,"28 Days","OBSERVATIONAL","Acute kidney injury(AKI) is defined in the KDIGO guidelines as a ≥0.3 mg\u002FdL (≥26.5 micromol\u002FL) increase in serum creatinine in the previous 48 hours or a ≥1.5-fold increase in serum creatinine from baseline, known or presumed to have occurred in the previous seven days, or a urine volume \\\u003C0.5 mL\u002Fkg\u002Fhour for six hours.\n\nGiven the high morbidity and mortality associated with AKI, many investigators are studying several novel biomarkers to detect AKI progression earlier, identify etiologies and predict outcomes. However, the utilisation of these novel biomarkers may be constrained by reimbursement considerations.\n\nThe renal resistive index (RRI) is a well-established metric for evaluating renal perfusion; however, its application in the context of AKI has been a subject of recent debate. While RRI has been utilised to demonstrate perfusion in acute and chronic renal diseases, particularly in conjunction with ultrasonography, its efficacy remains a subject of scientific discourse. In addition, Boddi reported that RRI is a strong indicator of mortality and a diagnostic marker, especially in patients with persistent AKI.\n\nThe present study aims to evaluate the appropriateness of using the RRI, a non-invasive procedure, to determine the progression of AKI stages and the need for renal replacement therapy in patients hospitalised in intensive care units.",[26,57],"Renal Replacement Therapy for Acute Kidney Injury in ICU",[28,59,60,61],"renal resistive index","renal replacement therapy","intensive care","2025-05-27",{"date":64,"type":35},"2025-05-29",{"date":66,"type":35},"2025-01-01",{"date":68,"type":20},"2026-07-01",{"name":41,"class":42}]