[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"alcohol-use-problem\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:alcohol-use-problem":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,40],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":29,"startDateStruct":32,"completionDateStruct":34,"leadSponsor":36,"locationsCount":39},"100537522","evaluating-signs-of-safety-a-deaf-accessible-therapy-toolkit-for-aud-and-trauma-100537522",false,"NCT06278922","Evaluating Signs of Safety: A Deaf-Accessible Therapy Toolkit for AUD and Trauma","Inclusion Criteria:\n\n* Self-identification as Deaf or hard-of-hearing\n* Proficiency in American Sign Language (ASL)\n* Age 18 years or older\n* Access to videoconferencing technology for informed consent and, if applicable, study therapy sessions\n* Access to online survey technology for study assessments\n* \"Problematic alcohol consumption, drinking behaviors, and alcohol-related problems\" on the AUD Identification Test (AUDIT), a 10-item screening measure developed by the World Health Organization that demonstrates good sensitivity and specificity in many populations (past-month referent time period; score ≥ 8 for men or ≥ 6 for women)\n* \"Subthreshold or full PTSD,\" on the PTSD Checklist for DSM-5 (PCL-5), a 20-item measure of PTSD symptoms reliably used to monitor symptom change (past-month referent time period; \"subthreshold\" = meets at least two DSM-5 diagnostic categories (B, C, D, and\u002For E) at moderate or high severity)\n\nExclusion Criteria:\n\n* Participation in concurrent formal psychotherapy (Note: Participants in all study conditions will be asked to refrain from concurrent formal psychotherapy. Participants who engage in formal psychotherapy outside of the research will be removed from the study at the point of treatment initiation. Outside treatment engagement will be queried at each assessment timepoint. If endorsed, the participant will be removed from the study at that timepoint, but data collected prior to treatment initiation will remain in the dataset. Aligning with the Seeking Safety model, Alcoholics Anonymous\u002FNarcotics Anonymous\u002FDual Recovery Anonymous attendance will be encouraged; attendance will be tracked as a potential outcome mediator.)\n* Members of the following special populations: Adults unable to consent; Individuals younger than 18 years; Prisoners; Pregnant women (Note: The investigators will not knowingly include pregnant women as participants; however, the investigators will not assess participants' pregnancy status.)","ALL","18 Years",{"count":18,"type":19},144,"ESTIMATED","INTERVENTIONAL",[22],"NA","The U.S. Deaf community - a group of more than one million Americans who communicate using American Sign Language (ASL) - experiences nearly triple the rate of lifetime problem drinking and twice the rate of trauma exposure compared to the general population. Although there are several treatments for alcohol use disorder (AUD) and posttraumatic stress disorder (PTSD) in hearing populations, none have been developed for or tested with Deaf clients. To address these barriers, the study team developed Signs of Safety, a Deaf-accessible therapy toolkit for treating AUD and PTSD. Their aims are to conduct a nationwide, virtual clinical trial to compare (1) Signs of Safety with (2) treatment as usual and (3) a no treatment control, to collect data on clinical outcomes, and to explore potential mediators and moderators of outcome.",[25,26],"PTSD","Alcohol; Use, Problem","RECRUITING","2026-06-12",{"date":30,"type":31},"2026-06-15","ACTUAL",{"date":33,"type":31},"2024-12-23",{"date":35,"type":19},"2028-11-30",{"name":37,"class":38},"University of Massachusetts, Worcester","OTHER",1,{"id":41,"slug":42,"hasResults":11,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":4,"eligibilityCriteria":46,"healthyVolunteers":47,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":48,"targetDuration":4,"studyType":20,"phases":50,"briefSummary":51,"conditions":52,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":53,"lastUpdatePostDateStruct":54,"startDateStruct":56,"completionDateStruct":58,"leadSponsor":60,"locationsCount":39},"100554637","using-ema-data-to-inform-a-web-intervention-for-couples-concerned-about-drinking-100554637","NCT06501677","Using EMA Data to Inform a Web-intervention for Couples Concerned About Drinking","Using Ecological Momentary Data to Inform a Web-intervention for Romantic Partners Concerned About Their Loved Ones Drinking","Concerned Partners:\n\nInclusion Criteria:\n\n* be at least 18 years of age\n* be in a romantic relationship\n* live with their partner\n* have a computer, tablet, or phone with internet access\n* have no plans to separate from partner in next 60 days\n* feel safe from partner violence\n\nExclusion Criteria:\n\n* report 4\u002F5+ on the AUDIT-C\n\nDrinking Partners:\n\nInclusion Criteria:\n\n* be at least 18 years of age\n* report 4\u002F5+ on the AUDIT-C\n* have a computer, tablet, or phone with internet access\n* feel safe from partner violence\n\nExclusion Criteria:\n\n* in current treatment for alcohol\n* concern about their CPs drinking",true,{"count":49,"type":19},275,[22],"Alcohol misuse is a prevalent and serious problem with significant harms to society, individuals, and their relationships. Romantic partners have a strong influence on their partner's behavior, uniquely positioning them as a motivator and supportive factor in changing their partner's alcohol use, but little evidence exists on the specific ways they can influence their partner. The impact this has on the quality of their relationship, communication, and overall well-being has yet to be explored. Thus, this study utilizes qualitative, quantitative, and ecological momentary assessment (EMA) data from both partners to develop a web-based intervention that applies communication-based personalized feedback to support the concerned partner (CP) in motivating their drinking partner (DP) to reduce drinking and other adverse relationship outcomes.",[26],"2026-04-22",{"date":55,"type":31},"2026-04-27",{"date":57,"type":31},"2025-04-22",{"date":59,"type":19},"2027-08",{"name":61,"class":38},"Stanford University"]