[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"all-adult-patients-undergoing-an-otolaryngology-procedure-with-inhaled-methoxyflurane-as-an-adjunct-to-topical-or-local-anesthesia\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:all-adult-patients-undergoing-an-otolaryngology-procedure-with-inhaled-methoxyflurane-as-an-adjunct-to-topical-or-local-anesthesia":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":26,"whyStopped":4,"lastUpdateSubmitDate":27,"lastUpdatePostDateStruct":28,"startDateStruct":31,"completionDateStruct":33,"leadSponsor":35,"locationsCount":4},"100593241","penthrox-in-otolaryngology-100593241",false,"NCT07003880","Penthrox in Otolaryngology","Inhaled Methoxyflurane for In-Office Procedures in Otolaryngology","PenthroxOTL","Inclusion Criteria:\n\n* All adult patients undergoing any of the following procedures with inhaled methoxyflurane as an adjunct to topical or local anesthesia:\n\n  * Skin lesion excision or reconstruction\n  * Fine or core needle aspiration biopsy\n  * Mucosal biopsy\n  * Laryngeal injection or biopsy\n  * Myringotomy with or without tympanostomy tube insertion\n  * Inferior turbinate reduction\n  * Septal button insertion\n\nExclusion Criteria:\n\n* Patient unable to complete the post-procedure questionnaire (either due to time constraints, neurocognitive impairment, etc.)\n* Presence of any contraindications to inhaled methoxyfluorane per product monograph:\n\n  * Patients less than 18 years of age\n  * Pregnancy, intended pregnancy, or current breast-feeding\n  * Inadequate patient understanding or lack of cooperation\n  * Decreased level of consciousness or head injury\n  * History of clinically significant renal impairment, e.g., reduced renal output\n  * History of liver dysfunction following previous exposure to halogenated anesthetics\n  * Current use of tetracycline antibiotics\n  * Personal or genetic history of malignant hyperthermia\n  * Muscular dystrophy","ALL","18 Years",{"count":20,"type":21},50,"ESTIMATED","OBSERVATIONAL","Our objective is to explore the use of methoxyflurane anesthesia as an adjunct analgesic to local anesthesia during in-office otolaryngology procedures in a prospective pilot study. The main outcome of this study will be patient satisfaction with the medication and analgesia. Secondary outcomes will include level of sedation and analgesia, patient-reported post-procedural pain levels, and any reported adverse events.",[25],"All Adult Patients Undergoing an Otolaryngology Procedure With Inhaled Methoxyflurane as an Adjunct to Topical or Local Anesthesia","NOT_YET_RECRUITING","2025-05-26",{"date":29,"type":30},"2025-06-04","ACTUAL",{"date":32,"type":21},"2025-06-01",{"date":34,"type":21},"2027-06-01",{"name":36,"class":37},"Sir Mortimer B. Davis - Jewish General Hospital","OTHER"]