[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"countryName\":\"Tajikistan\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":68},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,45],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100483779","expanding-medication-assisted-therapies-in-central-asia-100483779",false,"NCT05579470","Expanding Medication-Assisted Therapies in Central Asia","ExMAT CA","Inclusion Criteria:\n\ni. Aim 1: The inclusion criteria for Aim 1 Consists of:\n\n1. Quantitative surveys for PWID\n\n   1. 18 years or older\n   2. Meeting DSM-V criteria for opioid dependence\n   3. Be either treatment naïve and seeking OAT or be on OAT for \\\u003C 90 days\n2. Organizational Assessments for OAT Delivery Staff\n\n   1. 18 years or older\n   2. Currently working as an OAT delivery professional at an OAT delivery site\n3. Focus Groups (PWID on OAT)\n\n   1. 18 years or older\n   2. Meeting DSM-V criteria for opioid dependence\n   3. Be either treatment naïve and seeking OAT or be on OAT for \\\u003C 90 days\n4. Focus Groups (PWID not on OAT)\n\n   1. 18 years or older\n   2. Meeting Diagnostic and Statistical Manual of Mental Disorders(DSM)-V criteria for opioid dependence\n   3. Be OAT naïve (defined as never having been on OAT or having not received treatment for \\> 1 year)\n5. Focus Groups (OAT delivery staff)\n\n   1. 18 years or older\n   2. Currently working as an OAT delivery professional at an OAT delivery site\n\nii. Aim 2: The inclusion criteria for Aim 2 consists of:\n\n1. 18 years or older\n2. Currently assigned as a Chief Narcologist for an Oblast\n\niii. Aim 3: The inclusion criteria for Aim 3 consists of:\n\n1. 18 years or older\n2. Authorized as a professional to work at an OAT delivery site\n\nExclusion Criteria:\n\n* Not willing to provide consent","ALL","18 Years",{"count":19,"type":20},900,"ESTIMATED","INTERVENTIONAL",[23],"NA","Central Asia (CA) represents the most rapidly growing HIV epidemic region worldwide, concentrated in people who inject drugs (PWID) and their sexual partners, and scaling up opioid agonist therapies (OAT) in this region is the most cost-effective strategy to prevent new HIV infections, and more effective when combined with antiretroviral therapy (ART). The investigators propose to use the Network for the Improvement of Addiction Treatment (NIATx) implementation strategy to scale-up OAT in three diverse Central Asian countries (Kazakhstan, Kyrgyzstan, Tajikistan) and guided by the Exploration-Planning-Implementation-Sustainment (EPIS) framework. Understanding the trajectories of implementation and scale-up in this context may emerge through creating communities of practice, especially when cohesion and competence evolves, and may guide other healthcare delivery challenges in the region (e.g., HIV, TB); as well as build important regional expertise and understanding implementation trajectories should help support OAT program sustainability.",[26],"Opioid Use Disorder",[28,29,30,31],"HIV","OUD","OAT","Central Asia","RECRUITING","2025-09-16",{"date":35,"type":36},"2025-09-22","ACTUAL",{"date":38,"type":36},"2023-08-07",{"date":40,"type":20},"2026-12-31",{"name":42,"class":43},"Yale University","OTHER",4,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":49,"acronym":50,"eligibilityCriteria":51,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":52,"targetDuration":4,"studyType":21,"phases":54,"briefSummary":55,"conditions":56,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":59,"lastUpdatePostDateStruct":60,"startDateStruct":62,"completionDateStruct":64,"leadSponsor":66,"locationsCount":67},"100590024","pride-iii-prison-interventions-and-hiv-prevention-collaboration-100590024","NCT06962033","PRIDE III Prison Interventions and HIV Prevention Collaboration","PRIDE III","Inclusion Criteria:\n\nAim 1:\n\n1. Quantitative surveys for prison OAT providers\n\n   * Being 18 years or older\n   * Being currently assigned and working as a probation OAT provider for a probation site\n2. ECHO procedures\n\nAim 2:\n\n1. Quantitative surveys for people in probation\n\n   * Being 18 years or older\n   * Screen yes to opioid injection on the online screener questionnaire\n   * Currently in probation\n2. Quantitative surveys for probation and prison officers\n\n   * Being 18 years or older\n   * Being currently assigned and working as a probation or prison officer at a probation site\n3. Focus Groups (People in probation)\n\n   * Being 18 years or older\n   * Screen yes to opioid injection criteria on the online screener\n   * Currently in probation\n4. Focus Groups (Probation and prison officers)\n\n   * Being 18 years or older\n   * Being currently assigned and working as a probation or prison officer at a probation\n   * Has more than 3 months of field experience\n   * Works at a probation site within 25 kilometers of an OAT site\n\nExclusion Criteria:\n\n\\-",{"count":53,"type":20},300,[23],"The primary objective of this research project is to identify barriers to scale-up of Opioid Agonist Therapy (OAT) in the justice systems (prisons and probation) in Tajikistan, Kyrgyzstan, Moldova, and Georgia, and establish a NIATx learning collaborative to scale-up OAT, and analyze scale-up utilizing latent class growth analyses in people who inject drugs (PWID).",[57,58],"Hiv","Opioid Use","2025-05-08",{"date":61,"type":36},"2025-05-11",{"date":63,"type":36},"2024-11-05",{"date":65,"type":20},"2028-12",{"name":42,"class":43},5,""]