[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"allogeneic-hematopoietic-stem-cell-transplant-allo-hsct\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:allogeneic-hematopoietic-stem-cell-transplant-allo-hsct":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,42],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":26,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":4},"100640813","the-react-study-rehabilitation-and-activity-in-allogenic-transplant-100640813",false,"NCT07581093","The REACT Study: REhabilitation and ACTivity in Allogenic Transplant","A Longitudinal Study of Physical Function in Patients Undergoing Allogenic Stem Cell Transplant.","REACT","Inclusion Criteria:\n\n* Patients who are listed for allogeneic stem cell transplant.\n* Ability to provide written informed consent\n* Over 18 years old\n\nExclusion Criteria:\n\n* Nil","ALL","18 Years",{"count":20,"type":21},140,"ESTIMATED","OBSERVATIONAL","A prospective, longitudinal cohort study will be conducted to evaluate the effects of treatment on the physical function of patients undergoing Allogeneic Hematopoeitic Stem Cell Transplant.",[25],"Allogeneic Hematopoietic Stem Cell Transplant (Allo-HSCT)",[27,28,29],"Stem Cell Transplantation","Physical Functional Performance","Physical Activity","NOT_YET_RECRUITING","2026-05-06",{"date":33,"type":34},"2026-05-12","ACTUAL",{"date":36,"type":21},"2026-05-01",{"date":38,"type":21},"2029-12-28",{"name":40,"class":41},"University of Dublin, Trinity College","OTHER",{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":4,"eligibilityCriteria":48,"healthyVolunteers":11,"sex":17,"minAge":49,"maxAge":4,"enrollmentInfo":50,"targetDuration":4,"studyType":52,"phases":53,"briefSummary":55,"conditions":56,"keywords":57,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":59,"lastUpdatePostDateStruct":60,"startDateStruct":62,"completionDateStruct":64,"leadSponsor":66,"locationsCount":68},"100617172","phase-2-enteral-nutrition-versus-standard-of-care-in-allogeneic-hematopoietic-stem-cell-transplantation-100617172","NCT07315165","Enteral Nutrition Versus Standard of Care in Allogeneic Hematopoietic Stem Cell Transplantation","A Phase II Randomized Trial of Enteral Nutrition Versus Standard of Care in Allogeneic Hematopoietic Stem Cell Transplantation","Inclusion Criteria:\n\n* Diagnosis of a hematological condition or serious blood disorder\n* Patient planned for an allogeneic hematopoietic stem cell transplant\n* Any conditioning regimen or graft source\n\nExclusion Criteria:\n\n* Uncorrected anatomical deformity of the nose, nasopharynx, esophagus, or stomach that could prevent proper placement of a nasogastric tube.\n* Chronic gastrointestinal conditions causing malabsorption or need for nutritional supplementation, e.g., celiac disease, short gut syndrome, chronic use of total parental nutrition or enteral nutrition for 3 or more months. Uncorrected anatomical deformity may include any known significant deviated nasal septum, large nasal polyps or other masses, or nasal or oropharyngeal trauma.","19 Years",{"count":51,"type":21},112,"INTERVENTIONAL",[54],"PHASE2","This is a randomized controlled phase II trial which will enroll 112 patients with a diagnosis of a blood cancer or a serious blood disorder who plan to undergo an allogenic hematopoietic stem cell transplant using any conditioning regimen or graft source. Eligible patients will be randomized to receive standard of care (e.g., initiation of supplemental nutrition when oral intake declines) versus enteral nutrition via enteral feeding tube starting on day +1 post-transplant for at least 7 days, usually until engraftment. The primary endpoint will be cumulative incidence of stage 3-4 acute GVHD of the lower gut by day +100 post-transplant, whereas secondary endpoints will be stage 2-4 acute GVHD of the lower gut by day +100, grade 2-4 acute GVHD, weight loss and changes in lean muscle mass, changes in physical function, health-related quality of life, length of transplant hospital stay, and time to platelet and neutrophil engraftment. Assessments will include acute GVHD assessments and grading, Activities of Daily Living (ADL), Instrumental Activities of Daily Living (IADL), Fried Frailty Index, and Functional Assessment of Cancer Therapy-Bone Marrow Transplant (FACT-BMT).",[25],[58],"Enteral Nutrition; Acute GVHD; Stage 3-4; Stage 2-4 Gut GVHD; Nutritional Support; allo-HSCT.","2026-01-06",{"date":61,"type":34},"2026-01-08",{"date":63,"type":21},"2026-04",{"date":65,"type":21},"2031-04",{"name":67,"class":41},"University of Nebraska",1]