[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"alveolar-mucosa\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:alveolar-mucosa":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,45],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":30,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100632327","assessment-of-two-soft-tissue-augmentation-using-acellular-dermis-around-dental-implants-100632327",false,"NCT07512245","Assessment of Two Soft Tissue Augmentation Using Acellular Dermis Around Dental Implants","Assessment of Two Soft Tissue Augmentation Protocols Using Acellular Dermis for Augmentation of Soft Tissue Quantity and Quality Around Dental Implants","Inclusion Criteria:\n\n* English speaking\n* At least 18 years old\n* Must be a patient of the UAB Dental School\n* Able to read and understand informed consent document\n* Patients presenting with a single edentulous site planned for dental implant placement deemed deficient in soft tissue peri-implant phenotype (\\> 2mm width of keratinized tissue, \\\u003C 1mm marginal soft tissue thickness, and\u002For \\> 2mm vertical soft tissue height)\n* Presence of periodontally healthy, non-carious neighboring teeth and\u002For healthy restored dental implants on either side of edentulous site planned for dental implant placement.\n* No anticipated need for surgical and\u002For endodontic care at teeth adjacent to the proposed surgical site during the study period.\n\nExclusion Criteria:\n\n* Non-English speaking\n* Less than 18 years old\n* Smokers\u002Ftobacco users (\\>10 cigarettes\u002Fday)\n* Patients with systemic pathologies or conditions contraindicating oral surgical procedures or adversely affecting wound healing\n* Edentulous sites treatment planned for dental implant placement with adequate implant site soft tissue quality\u002Fquantity (\\> 2mm width of keratinized tissue, \\> 1mm marginal soft tissue thickness, and\u002For \\> 2mm vertical soft tissue height).\n* Absence of adjacent teeth\u002Fimplants on either side of the tooth to be extracted and\u002For edentulous sites where 2 or more adjacent implants are planned.",true,"ALL","18 Years","85 Years",{"count":21,"type":22},40,"ESTIMATED","INTERVENTIONAL",[25],"NA","This study aims to compare soft tissue grafting with acellular dermis at Phase I or Phase II dental implant surgery.",[28,29],"Acellular Dermal Matrix","Alveolar Mucosa",[31],"soft tissue graft","NOT_YET_RECRUITING","2026-06-22",{"date":35,"type":36},"2026-06-25","ACTUAL",{"date":38,"type":22},"2026-08",{"date":40,"type":22},"2028-12",{"name":42,"class":43},"University of Alabama at Birmingham","OTHER",1,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":4,"eligibilityCriteria":51,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":52,"targetDuration":4,"studyType":23,"phases":54,"briefSummary":55,"conditions":56,"keywords":58,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":44},"100538726","evaluation-of-free-gingival-graft-timing-100538726","NCT06294587","Evaluation of Free Gingival Graft Timing","Evaluation of Free Gingival Graft Timing in Staged Guided Bone Regeneration: A Randomized Controlled Trial","Inclusion Criteria:\n\n* • At least 18 years old\n\n  * No uncontrolled medical conditions or medications that will affect their bone healing.\n  * Good oral hygiene is defined as a full-mouth plaque score ≤25%11.\n  * Must be able to read and understand the informed consent document.\n  * Has a need for implants to replace missing tooth\u002Fteeth in at least 1 quadrant of the mouth.\n  * Insufficient alveolar ridge width for endosseous implant placement, defined as 5 mm or less, as determined by bone sounding and CBCT scan.\n  * The patient and\u002For guardian is willing and able to comply with pre-operative and post-operative diagnostic and clinical evaluations required.\n  * The patient is not pregnant or breastfeeding.\n\nExclusion Criteria:\n\n* Active infectious diseases.\n\n  * Liver or kidney dysfunction\u002Ffailure.\n  * Uncontrolled diabetes (HbA1c ≥ 8.5).\n  * Active cancer treatment - such as active chemotherapy radiation therapy, or radiotherapy performed within ≤12 months from the procedure.\n  * Taking medications that will affect their bone healing (for example, bisphosphonates and long-term anti-inflammatory medications).\n  * Metabolic bone diseases that affect bone healing such as osteoporosis.\n  * Pregnant or lactating women (self-reported).\n  * Current tobacco and Marijuana smokers have 10 or more cigarettes per day, and former smokers (\\&gt; 10 cigarettes) who quit \\&lt; 10 ago (self-reported).\n  * Poor oral hygiene.\n  * Vertical loss of bone at the edentulous ridge.\n  * History of periodontal disease.\n  * The patient is pregnant or breastfeeding",{"count":53,"type":22},30,[25],"This clinical trial aims to compare and evaluate the clinical outcomes between two distinct treatment sequences: free gingival graft surgery preceding guided bone regeneration and guided bone regeneration followed by free gingival graft.",[57,29],"Ridge Augmentation",[57,59,60],"Attached mucosa","Dental implants","RECRUITING","2025-08-04",{"date":64,"type":36},"2025-08-06",{"date":66,"type":36},"2024-08-12",{"date":68,"type":22},"2027-08-30",{"name":42,"class":43}]