[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"ambulatory-difficulty\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:ambulatory-difficulty":31},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":32,"overallStatus":43,"whyStopped":4,"lastUpdateSubmitDate":44,"lastUpdatePostDateStruct":45,"startDateStruct":48,"completionDateStruct":50,"leadSponsor":52,"locationsCount":5},"100598572","effects-of-intermittent-theta-burst-stimulation-itbs-on-motor-recovery-of-lower-extremity-in-chronic-stroke-patients-100598572",false,"NCT07073235","Effects of Intermittent Theta Burst Stimulation (iTBS) on Motor Recovery of Lower Extremity in Chronic Stroke Patients","Neuroplastic Changes and Effects of Intermittent Theta Burst Stimulation (iTBS) on Motor Recovery of Upper and Lower Extremity in Chronic Stroke Patients","NIMBLE","Inclusion Criteria:\n\n* Age over 18\n* Chronic stroke (\\>6 months)\n* Residual hemiparesis FAC ≥3\n\nExclusion Criteria:\n\n* Metal implants\n* Epilepsy\u002Fseizures\n* Pregnancy\n* Claustrophobia (related to MRIs exams)\n* Severe cognitive impairment\n* Untreated or unstable depression\u002Fanxiety\n* Other disabilities prohibiting intensive physical training","ALL","18 Years",{"count":20,"type":21},56,"ESTIMATED","INTERVENTIONAL",[24],"NA","This study aims to evaluate the effects and clinical feasibility of non-invasive brain stimulation protocols, specifically intermittent Theta Burst Stimulation, as part of rehabilitation interventions for motor recovery of lower extremity in the chronic phase after stroke.\n\nIt also seeks to explore the underlying mechanisms by investigating changes of functional and structural brain networks.",[27,28,29,30,31],"Stroke","Hemiparesis After Stroke","Chronic Stroke Patients","Hemiplegia","Ambulatory Difficulty",[33,34,35,36,37,38,39,40,41,42],"stroke","iTBS","TMS","Trancranial Magnetic Stimulation","Cerebellum","Chronic stroke patients","Balance","Walking","Hemiparesis","intermittent Theta Burst Stimulation","RECRUITING","2025-11-20",{"date":46,"type":47},"2025-11-25","ACTUAL",{"date":49,"type":21},"2025-11",{"date":51,"type":21},"2030-12",{"name":53,"class":54},"Danderyd Hospital","OTHER"]