[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"ambulatory-surgical-procedures\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:ambulatory-surgical-procedures":31},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,57,83],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":26,"conditions":27,"keywords":33,"overallStatus":44,"whyStopped":4,"lastUpdateSubmitDate":45,"lastUpdatePostDateStruct":46,"startDateStruct":49,"completionDateStruct":51,"leadSponsor":53,"locationsCount":56},"100597746","phase-2-clonidine-in-ultrasound-guided-rectus-sheath-block-for-outpatient-umbilical-hernioplasty-100597746",false,"NCT07062497","Clonidine in Ultrasound-guided Rectus Sheath Block for Outpatient Umbilical Hernioplasty","Ultrasound-guided Rectus Abdominis Muscle Sheath Block in Outpatient Umbilical Hernioplasties: a Comparative Analysis of the Use of Clonidine as an Adjuvant - Prospective Randomized Clinical Trial","Inclusion Criteria:\n\n* Adults aged 18 to 65 years;\n* Both male and female participants;\n* ASA physical status I or II (American Society of Anesthesiologists classification);\n* Scheduled for elective ambulatory umbilical hernia repair;\n* Hernial defect size ≤ 4 cm (small to medium).\n\nExclusion Criteria:\n\n* Refusal or inability to provide written informed consent;\n* Cognitive or psychiatric disorders that impair comprehension or adherence to the study protocol;\n* Known allergy or hypersensitivity to local anesthetics, clonidine, opioids, nonsteroidal anti-inflammatory drugs (NSAIDs), or other analgesics;\n* Participation in another clinical trial within the previous 30 days;\n* Missing data or loss to follow-up during postoperative assessments;\n* Contraindications to regional anesthesia or known coagulopathy.","ALL","18 Years","65 Years",{"count":20,"type":21},62,"ESTIMATED","INTERVENTIONAL",[24,25],"PHASE2","PHASE3","This clinical trial aims to evaluate the effectiveness of an ultrasound-guided nerve block technique as the sole anesthetic method for patients undergoing outpatient umbilical hernia surgery. The procedure, called rectus sheath block (RSB), involves injecting local anesthetic near the abdominal muscles to reduce pain during and after surgery. The study will compare two groups of adult patients: one receiving the nerve block with a medication called clonidine added to the anesthetic solution, and the other receiving the same block without clonidine. Clonidine may help improve pain control and reduce the need for additional pain medications. By analyzing pain scores, recovery quality, and potential side effects, the study seeks to determine whether the use of clonidine in this context is safe, cost-effective, and beneficial for patient recovery. Participants will answer questionnaires about their pain and recovery during the first 48 hours after surgery.",[28,29,30,31,32],"Hernia, Umbilical","Clonidine","Pain, Postoperative","Ambulatory Surgical Procedures","Regional Anesthesia Block",[34,35,36,29,37,38,39,40,41,42,43],"Rectus Sheath Block","Ultrasound-Guided Regional Anesthesia","Umbilical Hernia Repair","Local Anesthetics","Postoperative Pain Management","Ambulatory Surgery","Quality of Recovery","Alpha-2 Adrenergic Agonists","Pain Measurement","Analgesic Adjuvants","RECRUITING","2025-07-10",{"date":47,"type":48},"2025-07-14","ACTUAL",{"date":50,"type":48},"2025-01-07",{"date":52,"type":21},"2026-04-30",{"name":54,"class":55},"Universidade Federal do Rio de Janeiro","OTHER",1,{"id":58,"slug":59,"hasResults":11,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":4,"eligibilityCriteria":63,"healthyVolunteers":64,"sex":16,"minAge":17,"maxAge":65,"enrollmentInfo":66,"targetDuration":4,"studyType":22,"phases":68,"briefSummary":70,"conditions":71,"keywords":4,"overallStatus":44,"whyStopped":4,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":56},"100579088","efficacy-and-safety-of-cocktail-of-ropivacaine-for-local-infiltration-analgesia-in-patients-undergoing-laparoscopic-cholecystectomy-100579088","NCT06819748","Efficacy and Safety of Cocktail of Ropivacaine for Local Infiltration Analgesia in Patients Undergoing Laparoscopic Cholecystectomy","Efficacy and Safety of Cocktail of Ropivacaine,sodium Bicarbonate and Dexamethasone for Incision Local Infiltration Analgesia in Patients Undergoing Ambulatory Laparoscopic Cholecystectomy:A Prospective Randomized Control Trial","Inclusion Criteria:\n\n* Patients undergoing daytime laparoscopic cholecystectomy in Sichuan Provincial People's hospital ② Age: 18-70 years\n\n  * American society of Anesthesiologists physical status classification system I-II ④ 18 kg\u002F㎡≤ BMI ≤ 30 kg\u002F㎡ ⑤ No communication barriers, able to understand the research process and the use of pain scale.\n\n    * Signed informed consent\n\nExclusion Criteria:\n\n* Drug allergy related to this study\n\n  * History of chronic pain, long-term use of analgesic drugs (equivalent to ≥ 10mg oxycodone per day), alcohol abuse, gastrointestinal bleeding or perforation after application of non steroidal anti-inflammatory drugs\n\n    * Patients with ischemic heart disease, peripheral arterial vascular or cerebrovascular disease, or patients with pulmonary heart disease, active peptic ulcer or gastrointestinal bleeding, or patients with inflammatory bowel disease\n\n      * Patients taking monoamine oxidase inhibitors or within 2 weeks after discontinuation ⑤ Preoperative pain score (NRS ) was greater than or equal to 4 points ⑥ Participated in other clinical studies within three months",true,"70 Years",{"count":67,"type":21},210,[69],"NA","The goal of this clinical trial is to learn if the use of cocktail of ropivacaine,sodium bicarbonate and dexamethasone for incision local infiltration analgesia in patients undergoing ambulatory laparoscopic cholecystectomy is safe and effective. The main questions it aims to answer are:\n\nDoes the cocktail lower the The incidence of moderate to severe pain during movement stages within six hours after surgery.\n\nResearchers will compare the cocktail to ropivacaine for incision local infiltration analgesia to see if the cocktail works to moderate the postoperative pain of ambulatory laparoscopic cholecystectomy patients.\n\nParticipants will:\n\nReceive the cocktail or ropivacaine for incision local infiltration analgesia at the end of the surgery.\n\nAnswer the questions about postsurgical pain at rest or during motion(using a Numeric Rating Scale (NRS) of 0 to 10. Pain measurements were performed at 2, 6, 12, 24 hours,3,7,30 days and 3 months postoperatively.",[72,31,73],"Cholecystectomy, Laparoscopic","Multimodal Analgesia","2025-02-16",{"date":76,"type":48},"2025-02-19",{"date":78,"type":48},"2025-02-14",{"date":80,"type":21},"2025-09-01",{"name":82,"class":55},"Sichuan Provincial People's Hospital",{"id":84,"slug":85,"hasResults":11,"nctId":86,"briefTitle":87,"officialTitle":88,"acronym":89,"eligibilityCriteria":90,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":91,"targetDuration":93,"studyType":94,"phases":4,"briefSummary":95,"conditions":96,"keywords":104,"overallStatus":44,"whyStopped":4,"lastUpdateSubmitDate":107,"lastUpdatePostDateStruct":108,"startDateStruct":110,"completionDateStruct":112,"leadSponsor":114,"locationsCount":116},"100486389","the-fast-track-centre-for-hip-and-knee-replacement-database-100486389","NCT05613439","The Fast-track Centre for Hip and Knee Replacement Database","The Fast-track Centre for Hip and Knee Replacement Prospective Database on Preoperative Patientcharacteristics and Postoperative Complications","FCD","Inclusion Criteria:\n\n* age \\>18 years\n* non-malignant surgery\n* danish social security number\n* elective procedure\n\nExclusion Criteria:\n\n* unwilling to provide informed consent",{"count":92,"type":21},80000,"3 Months","OBSERVATIONAL","This is a prospective study-registry on preoperative patient characteristics and postoperative complications in patients having fast-track hip and knee replacement surgery in 8 Danish dedicated arthroplasty departments from all five health regions in Denmark. The registry consists of detailed patient and physician reported preoperative characteristics and including prescribed medication and lab results. Follow-up is based on electronical medical records by dedicated nurses with physician backup and includes Clavien-Dindo and Comprehensive Complication Index scoring. All patients having day-surgery also completes a patient reported questionaire on health-care utilization and return to work by day 30. Finally, a machine-learning algorithm for identification of \"high-risk\" patients based on he preoperative data is included.",[97,98,99,100,101,31,102,103],"Hip","Knee","Fast-track Surgery","Enhanced Recovery After Surgery","Perioperative Medicine","Perioperative\u002FPostoperative Complications","Patient Satisfaction",[105,106,101,100,102,31],"Hip Replacement","Knee Replacement","2024-08-06",{"date":109,"type":48},"2024-08-09",{"date":111,"type":48},"2022-09-01",{"date":113,"type":21},"2027-12-31",{"name":115,"class":55},"Rigshospitalet, Denmark",8]