[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"amelogenesis-imperfecta\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:amelogenesis-imperfecta":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,43],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":42},"100612232","oral-health-related-quality-of-life-of-children-with-amelogenesis-imperfecta-100612232",false,"NCT07250906","Oral Health Related Quality of Life of Children With Amelogenesis Imperfecta","Evaluation of the Impact of Anterior Veneers on the Quality of Life of Children With Amelogenesis Imperfecta","Inclusion Criteria:\n\n* Systemically healthy,\n* Aged between 11 and 14,\n* Diagnosed with Amelogenesis Imperfecta,\n* Need for anterior veneers,\n* Both female and male volunteers\n\nExclusion Criteria:\n\n* Those with systemic diseases,\n* Those with a history of allergies,\n* Those not diagnosed with Amelogenesis Imperfecta,\n* Those without an indication for veneers,\n* Those lacking adequate cooperation skills,\n* Patients younger than 11 or older than 14 years will not be included in the study.",true,"ALL","11 Years","14 Years",{"count":21,"type":22},20,"ESTIMATED","OBSERVATIONAL","This project aims to evaluate the impact of anterior veneer treatment on oral health-related quality of life in children with amelogenesis imperfecta (AI). AI is an inherited disorder that causes structural defects in enamel due to genetic abnormalities, leading to aesthetic, functional, and psychosocial challenges. Enamel defects, particularly in the anterior teeth, negatively affect patients' self-confidence and social interactions. In this study, the short-term aesthetic, functional, and psychosocial effects of veneer restorations applied to children with AI will be assessed.\n\nThis research is designed as a single-center, prospective clinical study. The study population will include pediatric patients aged 11-14 years who have been clinically and radiographically diagnosed with AI at our faculty clinic. Participants' oral health-related quality of life will be evaluated before treatment and one month after treatment using the Child Perceptions Questionnaire (CPQ11-14). Psychosocial improvement will be measured using the Rosenberg Self-Esteem Scale and the Psychosocial Impact of Dental Aesthetics Questionnaire (PIDAQ), while aesthetic satisfaction will be assessed using a Visual Analogue Scale (VAS). In addition, to objectively evaluate the participants' oral hygiene and dental health, the plaque index, gingival index, bleeding on probing index, and DMFT index will be recorded.\n\nThe data obtained are expected to demonstrate the positive impact of veneer treatment on the quality of life of children with AI, emphasizing the importance of early aesthetic rehabilitation in pediatric patients. In this respect, the study aims to provide a novel clinical and psychosocial contribution to the existing literature on the management of AI in pediatric dentistry.",[26],"Amelogenesis Imperfecta",[28,29],"quality of life","CPQ11-14","RECRUITING","2026-05-07",{"date":33,"type":34},"2026-05-12","ACTUAL",{"date":36,"type":34},"2025-11-24",{"date":38,"type":22},"2026-08-05",{"name":40,"class":41},"Istanbul University","OTHER",1,{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":49,"eligibilityCriteria":50,"healthyVolunteers":11,"sex":17,"minAge":51,"maxAge":52,"enrollmentInfo":53,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":55,"conditions":56,"keywords":59,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":42},"100416547","colorimetric-ultra-structural-and-elemental-comparison-of-dental-enamel-defects-100416547","NCT04704089","Colorimetric, Ultra-structural and Elemental Comparison of Dental Enamel Defects","Colorimetric Comparison of Email Defects Using Spectrophotometric and Computer Techniques and Biological, Structural and Physico-chemical Analyses of Teeth or Pathological Enamel","COLOEMAIL","For patients :\n\nInclusion Criteria :\n\n1. Age between 8 and 55 years old\n2. Carrier of one of the following 3 quantitative pre-eruptive enamel anomalies : AIH, dental fluorosis or MIH\n3. Information and collection of the non-opposition of the adult patient or of the representative(s) of parental authority present for the minors.\n\nCriteria for non-inclusion :\n\n1. Pregnant or breastfeeding woman\n2. Under guardianship or curators\n3. Opposition of the minor patient\n4. Presenting pre-eruptive anomalies only on the molars (the spectrophotometer can only take pictures of the anterior dental sector (incisors and canines)).\n5. Other types of hypomineralization (post-eruptive, of traumatic or infectious origin, idiopathic).\n6. Having undergone radiotherapy or chemotherapy inducing dental and periodontal damage.\n7. Having systemic abnormalities (unbalanced diseases), haemochromatosis, porphyria\n8. Under medication likely to disturb the coloring of the teeth\n\nFor witnesses :\n\nInclusion Criteria :\n\n1. Age between 8 and 55 years old\n2. Information and collection of the non-opposition of the adult witness or of the representative(s) of parental authority present for the minors.\n3. Free of any anomaly of tooth structure, exogenous dyschromia and carious lesions.\n\nCriteria for non-inclusion :\n\n1. Pregnant or breastfeeding woman\n2. Under guardianship or curators\n3. Opposition of the minor witness\n4. Carrier of a quantitative pre-eruptive enamel anomaly\n5. Polycarpus (preventing the diagnosis of amyl hypomineralization)","8 Years","55 Years",{"count":54,"type":22},80,"The study focuses on the analysis of enamel defects grouping together hypomineralization and hypoplasia. It focuses on 3 very characteristic enamel pathologies that are most often encountered in dental consultations: Molar Incisor Hypomineralization (MIH), dental fluorosis (FD) and amelogenesis imperfecta (AI). The research focuses on the use of a spectrophotometer for measuring tooth colors: the Zfx SpectroShade® (MHT) and its software as a means of early diagnosis of pre-eruptive enamel abnormalities. The main objective of the study is to analyze the color parameters of teeth affected with one of the 3 enamel abnormalities for use of the spectrophotometer as a non-invasive diagnostic tool for enamel defects.\n\nThe secondary objective is focused on the biological, structural and physicochemical characterizations of these different enamel pathologies from extracted teeth or enamel biopsies that must be ground to achieve a restoration.",[26,57,58],"Dental Fluoroses","Hypomineralization Molar Incisor",[60,61,62,63,64,65,66,67],"Colorimetry (MeSH)","Amelogenesis Imperfecta (MeSH)","Dental Fluorosis (MeSH)","Molar-incisor-Hypomineralization (MeSH)","Developmental Enamel Defects (MeSH)","Shade selection","Dental color matching","Diagnosis (MeSH)","2025-06-30",{"date":70,"type":34},"2025-07-03",{"date":72,"type":34},"2022-07-18",{"date":74,"type":22},"2026-04-18",{"name":76,"class":41},"Assistance Publique - Hôpitaux de Paris"]