[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"amount-of-corneal-flattening-kmax-flattening\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:amount-of-corneal-flattening-kmax-flattening":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":5},"100558305","topo-pachymetric-customized-accelerated-epi-on-vs-accelerated-epi-off-corneal-cross-linking-in-keratoconus-management-100558305",false,"NCT06549387","Topo-Pachymetric Customized Accelerated Epi-On Vs Accelerated Epi-Off Corneal Cross Linking in Keratoconus Management","Topo-Pachymetric Customized Accelerated Epithelium-On Versus Standard Accelerated Epithelium-Off Corneal Collagen Cross Linking in the Management of Keratoconus","Inclusion Criteria:\n\n1. Age: 18 years or older\n2. Corrected distance visual acuity (CDVA) of ≥ 0.3 Snellen.\n3. Central corneal thickness (de-epithelialized) of ≥ 400 micron.\n4. Corneal endothelial count of ≥ 2000.\n\nExclusion Criteria:\n\n1. Previous eye surgery\n2. The presence of lesions other than keratoconus, central or paracentral scaring\n3. History of Cross linking\n4. History of viral keratitis\n5. Connective tissue diseases\n6. Pregnancy or lactation during the study.\n7. The presence of nystagmus",true,"ALL","18 Years",{"count":20,"type":21},55,"ESTIMATED","INTERVENTIONAL",[24],"NA","The objective of this study is to compare the clinical effectiveness and safety of Topo-Pachymetric Customized Accelerated Epithelium-On (aCFXL) to Standard Accelerated Epithelium-Off (aCXL) Corneal Collagen Cross-Linking in the management of keratoconus. The study aims to evaluate visual and structural outcomes, to provide valuable insights into optimizing treatment strategies.",[27,28],"Amount of Corneal Flattening (Kmax Flattening)","Change in the Endothelial Cell Count","NOT_YET_RECRUITING","2024-08-09",{"date":32,"type":33},"2024-08-12","ACTUAL",{"date":35,"type":21},"2024-08-15",{"date":37,"type":21},"2025-04-30",{"name":39,"class":40},"Kasr El Aini Hospital","OTHER"]