[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"amputation-stump\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:amputation-stump":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,51],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":32,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":41,"startDateStruct":44,"completionDateStruct":46,"leadSponsor":47,"locationsCount":50},"100629532","negative-pressure-wound-therapy-as-a-predictor-of-persistent-pain-after-war-related-trauma-100629532",false,"NCT07475897","Negative Pressure Wound Therapy as a Predictor of Persistent Pain After War-Related Trauma","Negative Pressure Wound Therapy as a Predictor of Persistent Pain After War-Related Trauma: A Prospective Cohort Study","NPWT-Pain Stud","Inclusion Criteria:\n\n* age ≥18 years\n* war-related trauma (blast injury, fragmentation injury, gunshot wound, burn injury, or crush injury)\n* traumatic soft tissue injury requiring surgical management\n* ability to provide informed consent\n* availability for follow-up assessments\n\nExclusion Criteria:\n\n* chronic pain in the same anatomical region prior to injury\n* severe cognitive impairment preventing pain assessment\n* inability to communicate or complete questionnaires\n* refusal to participate\n* incomplete baseline data or loss to follow-up","ALL","18 Years","60 Years",{"count":21,"type":22},150,"ESTIMATED","OBSERVATIONAL","War-related trauma frequently causes complex soft tissue injuries that require repeated surgical treatment and advanced wound management techniques such as Negative Pressure Wound Therapy (NPWT). Although NPWT is widely used to promote wound healing and prepare wounds for reconstruction, its relationship with long-term pain outcomes remains unclear.\n\nThis prospective cohort study aims to investigate whether the use of NPWT after war-related trauma is associated with an increased risk of persistent post-traumatic pain six months after injury. Adult patients with traumatic soft tissue injuries requiring surgical management will be enrolled and followed for six months.\n\nIn addition to NPWT exposure, the study will evaluate several early clinical predictors of chronic pain, including acute pain intensity, number of surgical debridements, suspected nerve injury, and mechanism of trauma. Understanding these predictors may help clinicians identify high-risk patients early and develop targeted strategies for pain prevention and rehabilitation after severe trauma.",[26,27,28,29,30,31],"Phantom Limb Pain After Amputation","Chronic Pain Due to Injury","Postoperative Pain","Trauma (Including Fractures)","Amputation Stump","Amputation Stump; Infection",[33,34,35,36,37,38],"Negative Pressure Wound Therapy","War-related trauma","Post-traumatic pain","Neuropathic pain","Chronic pain after trauma","Soft tissue injury","NOT_YET_RECRUITING","2026-03-16",{"date":42,"type":43},"2026-03-18","ACTUAL",{"date":45,"type":22},"2026-03-15",{"date":45,"type":22},{"name":48,"class":49},"Charitable Organisation Charitable Fund Superhumans (Co Cf Superhumans)","OTHER",1,{"id":52,"slug":53,"hasResults":11,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":4,"eligibilityCriteria":57,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":58,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":60,"conditions":61,"keywords":65,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":4},"100600835","comparison-between-digital-nerve-microanastomosis-and-traction-neurectomy-in-post-digital-amputation-pain-100600835","NCT07102654","Comparison Between Digital Nerve Microanastomosis and Traction Neurectomy in Post-Digital Amputation Pain","Comparison Between Digital Nerve Microanastomosis and Traction Neurectomy in Post-Digital Amputation Pain: A Prospective Study","Inclusion Criteria:\n\n* Age ≥ 18 years\n* Patients who have undergone a traumatic digital amputation\n* Patients treated with one of the two following techniques: microanastomosis of digital nerves or traction neurectomy\n* Postoperative follow-up of at least 6 months\n\nExclusion Criteria:\n\n* Patients treated with a surgical intervention other than microanastomosis of digital nerves or traction neurectomy for digital amputation\n* Non-traumatic amputations (e.g., cancer or infection)\n* Follow-up of less than 6 months\n* Patients with pre-existing peripheral neuropathy",{"count":59,"type":22},50,"The goal of this prospective observational study is to assess the post-operative pain in adults with digital amputation following two different surgical interventions: microanastomosis of digital nerves or traction neurectomy. The main questions it aims to answer are:\n\n* Which surgical intervention results in less post-operative pain?\n* Which surgical intervention leads to fewer symptoms after six months?\n* Which surgical intervention is associated with fewest post-operative complications? Participants will complete a Visual Analog Scale (VAS) to assess the pain and the Disabilities of the Arm, Shoulder and Hand Questionnaire (DASH) to evaluate the disabilities.\n\nThe researchers will assess post-operative complications during follow-up appointments.",[30,62,63,64],"Amputation Neuroma","Amputation, Traumatic\u002FSurgery","Amputation, Surgical",[66,67,68,69],"microanastomosis","traction neurectomy","digital amputation","digital nerve","2025-09-11",{"date":72,"type":43},"2025-09-15",{"date":74,"type":22},"2025-12-01",{"date":76,"type":22},"2026-07-01",{"name":78,"class":49},"Centre hospitalier de l'Université de Montréal (CHUM)"]