[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"amyotrophic-lateral-sclerosis-andor-frontotemporal-dementia\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:amyotrophic-lateral-sclerosis-andor-frontotemporal-dementia":31},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":5},"100283059","diagnosing-frontotemporal-lobar-degeneration-100283059",false,"NCT02964637","Diagnosing Frontotemporal Lobar Degeneration","Multimodal Assessment for Predicting Specific Pathological Substrate in Frontotemporal Lobar Degeneration","Inclusion Criteria:\n\n* Participant must have a reliable study partner who can provide an independent evaluation of functioning.\n* Able to read, understand and speak English for neuropsychological testing.\n* All subjects must meet one of these diagnostic criteria (A) probable behavioral variant FTD, (B) MRI-supported non-fluent variant PPA; (C) MRI-supported semantic variant PPA and \\[18F\\]T807 negative (D) probable CBS: using current criteria for CBS(27); (E) PSP: inclusion criteria for PSP are based upon the National Institute of Neurological Disorders and Stroke Society of Progressive Supranuclear Palsy (NINDS-SPSP) (F) FTD-MND\n* Control subjects must have a normal neurological exam, a CDR sum of boxes = 0, and MMSE score equal to or greater than 28\n\nExclusion Criteria:\n\n* Patients with clinical, imaging or CSF A beta\u002F tau profile consistent with AD\n* History of traumatic brain injury, brain tumors, stroke or other neurological or psychiatric disorders that can explain symptoms will be excluded.\n* Premenopausal women will be asked to consent to a pregnancy test prior to each scan as pregnant women will be excluded from study because of potential harm to fetus from PET study.\n* Presence of pacemakers, aneurysm clips, artificial heart valves, ear implants, metal fragments or foreign objects in the eyes, skin or body.",true,"ALL","18 Years","90 Years",{"count":21,"type":22},100,"ESTIMATED","OBSERVATIONAL","To establish diagnostic tools to make an accurate clinical and pathological diagnosis of patients with clinical FTLD syndromes",[26,27,28,29,30,31],"Corticobasal Syndrome","Progressive Supranuclear Palsy","Behavioral Variant Frontotemporal Dementia","Semantic Dementia","Progressive Nonfluent Aphasia","Amyotrophic Lateral Sclerosis And\u002For Frontotemporal Dementia","RECRUITING","2025-03-25",{"date":35,"type":36},"2025-03-30","ACTUAL",{"date":38,"type":4},"2015-08",{"date":40,"type":22},"2026-12",{"name":42,"class":43},"University Health Network, Toronto","OTHER"]