[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"anaesthesia\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:anaesthesia":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,48,81,113,141],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":32,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100607290","phase-4-perioperative-medicine-platform-trial-100607290",false,"NCT07186634","PeRiOperative Medicine Platform Trial","Domain-Specific Appendix: OXYGEN","PROMPT","PROMPT - Inclusion Criteria:\n\n* Adult patient (≥18 years of age at time of admission)\n* Scheduled to undergo a surgical procedure involving a skin incision, with an expected duration of at least 2 hours, and a planned overnight hospital stay of at least 1 night (including, but not limited to, cardiac surgery, orthopedic surgery, obstetric, or gynecological surgery).\n\nPROMPT - Exclusion Criteria:\n\n* ASA physical status 5 (moribund, not expected to survive with or without an operation)\n* Inability to provide informed consent\n* Previous participation in PROMPT within the prior 30 days.\n\nDSA 02 - PROMPT - Exclusion Criteria:\n\n* ASA physical status 1 or 2\n* Undergoing cardiac surgery\n* Undergoing thoracic surgery if one-lung ventilation is required\n* Currently suspected or proven infection\n* Advanced lung disease requiring home oxygen therapy\n* Previous bleomycin therapy\n* Known or suspected pregnancy","ALL","18 Years",{"count":20,"type":21},7800,"ESTIMATED","INTERVENTIONAL",[24],"PHASE4","Our specific aims are to investigate whether conservative (≤30%), intermediate (50%), or liberal (80%) inspired oxygen during and immediately after surgery: Aim 1: Reduces surgical site infections (SSIs or \"wound infections\") and other healthcare-associated infections (pneumonia and sepsis). Aim 2: Reduces a pooled composite of serious postoperative complications, leading to a faster and more complete recovery after surgery, and thus increases \"days alive and at home up to 30 days after surgery\" (DAH30). Primary hypothesis: Liberal (80%) oxygen concentration delivered with anesthesia in patients undergoing major surgery reduces the incidence of SSIs after surgery compared to conservative (≤30%) or intermediate (50%) oxygen concentration. Secondary hypothesis: Hyperoxia (50-80%) delivered with anesthesia in patients undergoing major surgery increases the incidence of pulmonary and other complications after surgery compared to conservative (≤30%) oxygen concentration, resulting in fewer Days At Home (DAH). PROMPT enrolls patients undergoing elective or semi-elective surgery.",[27,28,29,30,31],"Surgical Site Infection After Major Surgery","Anaesthesia","Major Complications","Quality of Recovery (QoR-15)","Quality of Life",[33,34],"Anaesthesiology, complications, oxygen, surgery","platform trial","RECRUITING","2026-04-14",{"date":38,"type":39},"2026-04-17","ACTUAL",{"date":41,"type":39},"2026-04-06",{"date":43,"type":21},"2035-12",{"name":45,"class":46},"Monash University","OTHER",2,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":54,"eligibilityCriteria":55,"healthyVolunteers":11,"sex":17,"minAge":56,"maxAge":57,"enrollmentInfo":58,"targetDuration":4,"studyType":60,"phases":4,"briefSummary":61,"conditions":62,"keywords":64,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":80},"100611828","monitoring-the-depth-of-anesthesia-and-nociception-during-the-induction-of-general-anesthesia-in-pediatric-patients-100611828","NCT07245654","Monitoring the Depth of Anesthesia and Nociception During the Induction of General Anesthesia in Pediatric Patients","Monitoring the Depth of Anesthesia and Nociception During the Induction of General Anesthesia in Pediatric Patients: a Prospective Observational Study","ANIGAPP","Inclusion Criteria:\n\n* Pediatric patients (age 1-19 years) indicated for surgery under general anesthesia with airway management (laryngeal mask, orotracheal intubation, nasotracheal intubation)\n* CONOX monitoring available\n\nExclusion Criteria:\n\n* Age out of range\n* Use of ketamine during anesthesia care (premedication, analgesic, anesthetic)\n* Expected duration of surgery less than 30 minutes\n* CONOX monitoring unavailable","1 Year","19 Years",{"count":59,"type":21},100,"OBSERVATIONAL","Perioperative assessment of adequate depth of anesthesia and analgesia is currently a recommended part of routine anesthesia practice for all surgical procedures. In most cases, it is performed by monitoring and evaluating physiological parameters, which is insufficient, especially for the depth of anesthesia. The depth of anesthesia, when measured with the Conox device, is indicated by the qCON index, the recommended value for anesthesia management is between 40-60. Shallow (above 60) anesthesia may be associated with an increased incidence of perioperative wakefulness episodes, and deeper (below 40) anesthesia may lead to a more frequent occurrence of adverse effects of anesthesia, including emergent delirium in the postoperative period. In addition to assessing the depth of anesthesia, the Conox device also allows for instrumental assessment of analgesia. Inadequate analgesia increases postoperative discomfort and may contribute to an increased incidence of complications in anesthesia and during the postoperative period. Instrumental monitoring of the depth of anesthesia and analgesia increases the safety of anesthesia care. During perioperative care, periods with significant painful stimulation include not only the surgical procedure itself but also airway management during induction of general anesthesia, especially intubation. The hypothesis is - due to the significant painful stimulation during airway management during induction of anesthesia, adequate depth of anesthesia and analgesia may be insufficient and is associated with the patient's clinical response, which may be associated with the occurrence of postoperative delirium.",[28,63],"Anesthesia Depth Monitoring",[65,66,67,68,69,70],"depth of anesthesia","pediatric","nociception","awareness","depth of analgesia","airway management","2025-11-17",{"date":73,"type":39},"2025-11-24",{"date":75,"type":39},"2025-11-10",{"date":77,"type":21},"2026-12-31",{"name":79,"class":46},"Brno University Hospital",1,{"id":82,"slug":83,"hasResults":11,"nctId":84,"briefTitle":85,"officialTitle":86,"acronym":4,"eligibilityCriteria":87,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":88,"targetDuration":4,"studyType":60,"phases":4,"briefSummary":90,"conditions":91,"keywords":96,"overallStatus":103,"whyStopped":4,"lastUpdateSubmitDate":104,"lastUpdatePostDateStruct":105,"startDateStruct":107,"completionDateStruct":109,"leadSponsor":111,"locationsCount":80},"100597393","comparison-of-intubation-using-video-laryngeal-mask-and-video-laryngoscope-in-elective-surgical-patients-100597393","NCT07057908","Comparison of Intubation Using Video Laryngeal Mask and Video Laryngoscope in Elective Surgical Patients","A Prospective Observational Study Comparing Tracheal Intubation Via Video Laryngeal Mask Airway and Video Laryngoscope in Adult Patients Undergoing Elective Surgery","Inclusion Criteria:\n\n* Adult patients aged 18 years and older\n* Patients scheduled for elective surgical procedures\n* Patients classified as ASA Physical Status I-III\n* Patients undergoing general anesthesia\n\nExclusion Criteria:\n\n* Patients younger than 18 years\n* Patients undergoing emergency surgery\n* Patients with difficult airway predictors, such as:\n\nMallampati score ≥ 3\n\nThyromental distance \\\u003C 6 cm\n\nMouth opening \\\u003C 3 cm\n\n* Patients with anatomical abnormalities or surgical history involving the oropharynx, larynx, or airway\n* Patients with conditions contraindicating head or neck manipulation (e.g., cervical instability, upper airway tumors)\n\nPregnant patients",{"count":89,"type":21},176,"This study compares two airway devices that are commonly used during elective surgery: the video laryngeal mask airway (VLM) and the video laryngoscope (VLS). Both are part of routine anesthesia practice. Our main focus is to measure how long intubation takes with each device and to see how successful the intubation is. The study does not involve any extra procedures or risks; everything will be carried out as part of normal patient care.",[92,93,94,95,28],"Airway Management","Tracheal Intubation","Elective Surgeries","Videolaryngoscopy",[97,98,99,100,101,102],"Video Laryngoscope","Video Laryngeal Mask Airway","SaCoVLM","Intubation Success Rate","Observational Study","Elective Surgical Patients","NOT_YET_RECRUITING","2025-08-28",{"date":106,"type":39},"2025-09-05",{"date":108,"type":21},"2025-09-01",{"date":110,"type":21},"2026-03-02",{"name":112,"class":46},"Samsun University",{"id":114,"slug":115,"hasResults":11,"nctId":116,"briefTitle":117,"officialTitle":117,"acronym":118,"eligibilityCriteria":119,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":120,"targetDuration":4,"studyType":60,"phases":4,"briefSummary":122,"conditions":123,"keywords":127,"overallStatus":103,"whyStopped":4,"lastUpdateSubmitDate":134,"lastUpdatePostDateStruct":135,"startDateStruct":137,"completionDateStruct":138,"leadSponsor":140,"locationsCount":4},"100601401","the-role-of-simulation-based-training-in-resident-curriculum-in-anaesthesia-and-intensive-care-100601401","NCT07110012","The Role of Simulation-based Training in Resident Curriculum in Anaesthesia and Intensive Care","STRAIC","Inclusion Criteria:\n\n* ESAIC NASC representatives.\n\nExclusion Criteria:\n\n* not ESAIC NASC representatives.",{"count":121,"type":21},200,"This observational study aims to describe the situation in Europe regarding simulation training during residency in Anaesthesia and Intensive Care. The main questions it aims to answer are:\n\nHow many countries in Europe have obligatory simulation training during residency? How frequent is this training? What and how is trained during simulations? How is the situation regarding funding and participation in working hours in simulation training? What are the obstacles for the countries that do not have obligatory training? Participants will fill out an electronic survey.",[124,125,126,28],"Simulation Training","Education","Critical Care, Intensive Care",[128,129,130,131,132,133],"simulation training","intensive care","European survey","education","physicians","Anesthesia","2025-07-31",{"date":136,"type":39},"2025-08-07",{"date":108,"type":21},{"date":139,"type":21},"2025-12-30",{"name":79,"class":46},{"id":142,"slug":143,"hasResults":11,"nctId":144,"briefTitle":145,"officialTitle":146,"acronym":4,"eligibilityCriteria":147,"healthyVolunteers":148,"sex":17,"minAge":18,"maxAge":149,"enrollmentInfo":150,"targetDuration":4,"studyType":22,"phases":152,"briefSummary":154,"conditions":155,"keywords":4,"overallStatus":103,"whyStopped":4,"lastUpdateSubmitDate":158,"lastUpdatePostDateStruct":159,"startDateStruct":161,"completionDateStruct":162,"leadSponsor":164,"locationsCount":80},"100599395","ultrasound-guided-supraclavicular-block-with-vs-without-pns-100599395","NCT07083934","Ultrasound-Guided Supraclavicular Block With vs Without PNS","Comparison of Ultrasound Guided Supraclavicular Brachial Plexus Block With and Without Peripheral Nerve Stimulation (PNS) Guidance: A Randomized Controlled Tria","Inclusion Criteria:\n\n* Aged 18 years and older\n* ASA physical status I to IV\n* No contraindications to regional anaesthesia\n* Operative site located at the mid to lower arm, including the elbow, forearm, wrist, or hand\n* Ability to provide informed consent\n* Ability to reliably report symptoms to the research team related to regional anaesthesia\n\nExclusion Criteria:\n\n* Patient's refusal to participate.\n* Inability to provide first-party consent due to cognitive impairment.\n* Cognitive dysfunction which can lead to difficulties in communication and cooperation of patient.\n* Preexisting neuropathy.\n* Preexisting coagulopathy.\n* Patients who will be shifted to ICU due to post - operative ventilatory support.",true,"80 Years",{"count":151,"type":21},44,[153],"NA","Peripheral Nerve Blockade (PNB) became reliable with the advent of Ultrasound (US) and Peripheral Nerve Stimulation (PNS).\n\nUS offers real-time visualization but has limitations, especially with deep or obscured nerves.\n\nPNS complements US by confirming nerve proximity through motor responses. Combining both may enhance safety and success of nerve blocks. This study compares US-guided blocks with and without PNS in a randomized trial.",[156,157,28],"Supraclavicular Plexus Block","Ultrasound","2025-07-22",{"date":160,"type":39},"2025-07-24",{"date":108,"type":21},{"date":163,"type":21},"2026-01-31",{"name":165,"class":46},"Aga Khan University"]