[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"anal-cancer-squamous-cell\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:anal-cancer-squamous-cell":31},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,45],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100628637","improving-clinic-delivery-of-hiv-related-anal-health-services-100628637",false,"NCT07464236","Improving Clinic Delivery of HIV-related Anal Health Services","Partnering to Enhance Anal Health Communication and HIV-related Evidence-based Services","PEACHES 2","Inclusion Criteria:\n\nStaff participants (\"Strategy Recipients\" and \"Strategy Recipients\")\n\n* employed at one of eight Coastal Family Health Center clinics at the time of the survey\n* over age 18 years old\n\nPatient participants (\"Patients\")\n\n* accessing sexual health services at one of eight Coastal Family Health Center clinics in the last 12 months\n* over 18 years old\n\nExclusion Criteria:\n\n* Staff or patients who are unable to provide informed consent (e.g., significant cognitive impairment)\n* Individuals currently incarcerated or in state custody\n* Patients whose only visits are for non-HIV, non-STI issues and who do not meet the EMR-based eligibility criteria above",true,"ALL","18 Years",{"count":21,"type":22},8,"ESTIMATED","INTERVENTIONAL",[25],"NA","This project will test ways to reduce stigma in healthcare settings so that more providers offer, and more patients receive, important anal sex-related HIV services, including anorectal sexually transmitted infection (STI) testing, preventive medications, and cancer screening. By evaluating these stigma-reduction strategies in eight clinics in the Mississippi Delta, a region with high rates of HIV and STIs, the research team will learn whether and how these approaches work to improve access to care. The results will help guide healthcare systems in using the most effective methods to reduce stigma, making it easier for people to get prevention services and improving public health.",[28,29,30,31],"HIV","Gonorrhea","Chlamydia","Anal Cancer Squamous Cell","NOT_YET_RECRUITING","2026-06-02",{"date":35,"type":36},"2026-06-03","ACTUAL",{"date":38,"type":22},"2026-08-01",{"date":40,"type":22},"2030-07-31",{"name":42,"class":43},"Albert Einstein College of Medicine","OTHER",1,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":51,"eligibilityCriteria":52,"healthyVolunteers":11,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":53,"targetDuration":4,"studyType":23,"phases":55,"briefSummary":56,"conditions":57,"keywords":58,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":71},"100397970","proton-versus-photon-therapy-in-anal-squamous-cell-carcinoma-100397970","NCT04462042","Proton Versus Photon Therapy in Anal Squamous Cell Carcinoma","Proton Versus Photon Therapy in Anal Squamous Cell Carcinoma - Swedish Anal Carcinoma Study","SWANCA","Inclusion Criteria:\n\n1. The patient must be at least 18 years old\n2. Histologically confirmed, previously untreated squamous cell carcinoma (p16-positive or p16-negative) of the anal canal (ICD-O-3 C21), i.e. cancer of the perianal skin without connection to the anal canal are not included. The patients may have primary tumour, regional nodes, metastasis (TNM)-stage T2 (\\>4 cm) -4,N0-1c,M0 (UICC 8th edition).\n3. World Health Organisation\u002FEastern Cooperative Oncology Group (WHO\u002FECOG) performance status 0-1\n4. The patient must be able to understand the information about the treatment and give a written informed consent.\n\nExclusion Criteria:\n\n1. Patients with cancer of the perianal skin without involvement of the anal canal (ICD-O-3 C44.5) are not eligible.\n2. Patient judged to have any other treatment than radiotherapy with concomitant chemotherapy as the preferred treatment\n3. Concomitant or previous malignancies. Exceptions are, adequately treated basal cell carcinoma or squamous cell carcinoma of the skin or, other previous malignancy with a disease-free interval of at least 5 years.\n4. Two or more synchronous primary cancers in the pelvic region at time of diagnosis\n5. Previous radiotherapy, surgery or chemotherapy that may interfere with the planned treatment for the present disease, as judged by the investigator.\n6. Co-existing disease prejudicing survival (expected survival should be \\>2 years).\n7. Pregnancy or breast feeding\n8. When prosthetic materials (e.g. hip prostheses) are present close to the target volume it must be considered if this may introduce uncertainties in dose calculations that precludes especially, proton therapy.\n9. Patients with pacemaker\u002FICD are not eligible.",{"count":54,"type":22},100,[25],"Dosimetric studies suggest that radiotherapy with protons has a potential to reduce side effects compared to treatment with photons for patients with anal carcinoma (AC). There are so far no studies comparing these treatment techniques in a randomised setting. The aim of this study is to compare side effects following photon therapy versus proton therapy within the framework of a randomised controlled trial.",[31],[59,60],"proton beam therapy","side effects","RECRUITING","2025-03-28",{"date":64,"type":36},"2025-04-03",{"date":66,"type":36},"2021-04-07",{"date":68,"type":22},"2031-03-28",{"name":70,"class":43},"Umeå University",4]