[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"anal-incontinence\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:anal-incontinence":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,42,70,105,141],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":26,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100618776","impact-on-postpartum-anal-incontinence-of-an-educational-program-for-delivery-room-staff-100618776",false,"NCT07336017","Impact on Postpartum Anal Incontinence of an Educational Program for Delivery Room Staff","Impact on Postpartum Anal Incontinence of an Educational Program for Delivery Room Staff on the Diagnosis and Repair of Obstetric Anal Sphincter Injuries","IIA-LOSA","Inclusion Criteria:\n\n* Adult women (≥18 years old)\n* who gave birth vaginally at Strasbourg University Hospital in the 3 months prior to and 3 months following the training of delivery room staff at both maternity wards\n* Singleton pregnancy\n* Live birth\n\nExclusion Criteria:\n\n* Multiple pregnancy\n* Fetal death in utero\n* Medical termination of pregnancy\n* Delivery by cesarean section.","FEMALE","18 Years",{"count":20,"type":21},1000,"ESTIMATED","OBSERVATIONAL","Obstetric anal sphincter injuries are a source of significant short-term (pain, bleeding, infection, suture dehiscence), medium-term (anorectovaginal fistulas, sexual dysfunction), and long-term (anal incontinence in 30-60% of cases) morbidity. However, they are underdiagnosed and sometimes poorly repaired due to technical difficulties, the use of inappropriate surgical techniques, or a lack of awareness of their significant long-term morbidity. These diagnostic and therapeutic errors, however, significantly worsen the functional prognosis of patients. This study aims to evaluate the clinical impact of an educational program designed for continuing education in the diagnosis and repair of obstetric anal sphincter injuries for staff working in the delivery room.",[25],"Anal Incontinence",[25,27,28],"Postpartum Anal Incontinence","Obstetric Anal Sphincter Injuries","RECRUITING","2026-01-02",{"date":32,"type":33},"2026-01-13","ACTUAL",{"date":35,"type":33},"2025-06-17",{"date":37,"type":21},"2026-12-17",{"name":39,"class":40},"University Hospital, Strasbourg, France","OTHER",1,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":4,"eligibilityCriteria":48,"healthyVolunteers":49,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":50,"targetDuration":4,"studyType":52,"phases":53,"briefSummary":55,"conditions":56,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":41},"100600961","pelvic-floor-muscle-training-during-pregnancy-100600961","NCT07104292","Pelvic Floor Muscle Training During Pregnancy","PFMT During Pregnancy - Its Implementation and Effects on Pelvic Floor Disorders, Sexual Function and Obstetric Outcomes: a Hybrid Type 1 Design Randomised Controlled Trial","Inclusion Criteria:\n\n* Woman in the 1st trimester of pregnancy (up to 12+6 weeks of gestation)\n* Para 0 (no previous birth or pregnancy \\> 16 weeks of gestation)\n* Understands, writes, and reads fluently in Danish or English\n* Has a smart phone or computer\u002Ftablet to reach the training program\n\nExclusion Criteria:\n\n* Severe psychiatric illness (e.g. schizophrenia, bipolar disorder, severe depression or anxiety)\n* Active substance abuse\n* Acute social crises (e.g. homelessness, ongoing domestic violence, severe financial instability, lack of social support)\n* Women with limited capacity to provide informed consent (due to cognitive impairment or language barriers)\n* Previous pregnancy of \\> 16 weeks of gestation",true,{"count":51,"type":21},734,"INTERVENTIONAL",[54],"NA","The project seeks to investigate effectiveness of PFMT during pregnancy.",[57,58,25,59,60],"Pelvic Floor","Urinary Incontinence","Pelvic Organ Prolapse","Sexual Dysfunction","2025-11-21",{"date":63,"type":33},"2025-11-28",{"date":65,"type":33},"2025-10-27",{"date":67,"type":21},"2028-08-01",{"name":69,"class":40},"University of Southern Denmark",{"id":71,"slug":72,"hasResults":11,"nctId":73,"briefTitle":74,"officialTitle":75,"acronym":76,"eligibilityCriteria":77,"healthyVolunteers":49,"sex":17,"minAge":18,"maxAge":78,"enrollmentInfo":79,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":81,"conditions":82,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":103,"locationsCount":41},"100527077","care-for-oasi-study-care-pathways-and-anorectal-evaluation-for-oasi-associated-incontinence-100527077","NCT06143072","CArE for OAsI Study: Care Pathways and Anorectal Evaluation for OASI Associated Incontinence","Referral Pathways and Care Provision for Patients Who Develop OASI Associated Incontinence in the First Five Years Following a Vaginal Delivery","CArE for OAsI","Part 1 of Study\n\nInclusion Criteria:\n\n* • Fertile women ≥ 18 years and ≤50 who have developed OASI related incontinence following a vaginal delivery in the preceding five years (N.B. the average age of menopause in the UK is 51)\n\n  * Tertiary referrals to the specialist perineal clinic as well as patients who have 'slipped' through the existing pathway of referral\n  * Capacity to consent (able to comprehend and retain information, weight out the risks and benefits and communicate a decision back to the researcher)\n  * English-speaking and able to comprehend and read English\n  * Primiparous\u002Fmulti-parous\n\nExclusion Criteria:\n\n* • Women who are unable to consent or who have severe mental illness, as decided by the screening clinician\n\n  * Patients who do not speak, read or understand English\n  * Patients with an alternative documented cause for their FI that is non obstetric trauma related.\n  * Post-menopausal women who may develop late onset symptoms of incontinence relating to a previous OASI (clinically silent injuries that manifest in later life secondary to hormonal influences or advancing age for example).\n  * Women with an OASI who have been referred directly from the maternity unit at the same trust as the specialist perineal clinic, where an existing trust policy exists for direct referral of these patients from the maternity unit to the perineal clinic.\n\nPart 2 of study:\n\nInclusion criteria:\n\n• urogynaecologists\u002Fobstetricians who oversee the care of or look after patients with OASI and who are practising in UK NHS hospitals at the time of completion of the survey. They must be on the GMC specialist register to be eligible to participate\n\nExclusion criteria:\n\n• trainees, obstetricians\u002Fgynaecologists not routinely involved in the care of OASI patients.","50 Years",{"count":80,"type":21},112,"The aim of this study is to ascertain which pathways currently exist in relation to the follow up of patients with obstetric anal sphincter injury related incontinence. This is particularly important as afflicted individuals may not readily volunteer information about their symptoms and struggles and need to be safeguarded by the presence of robust care pathways that ensure adequate follow up and care provision.\n\nAs obstetric anal sphincter injuries have been associated with increased litigation rates over the years, positive interventions towards patient care will help ameliorate the financial burden that litigation carries on the National Health Service. It is noteworthy of mention that perineal injury, in itself, may not be suggestive of negligent care and is a recognized complication of vaginal delivery. However, a failure to adequately manage the injury may carry medicolegal implications.",[83,84,85,86,25,87,88,89,90,91,92,93,94,95],"Obstetric Anal Sphincter Injury","Severe Perineal Trauma","Grade 3 Perineal Tear","Grade 4 Perineal Tear","Faecal Incontinence","Urgency","Deferral Time","Pathways","Follow-up","Review","Endo-anal Ultrasound","Urogynaecology","Biofeedback","2025-05-21",{"date":98,"type":33},"2025-05-25",{"date":100,"type":33},"2024-01-01",{"date":102,"type":21},"2025-07-01",{"name":104,"class":40},"London North West Healthcare NHS Trust",{"id":106,"slug":107,"hasResults":11,"nctId":108,"briefTitle":109,"officialTitle":109,"acronym":110,"eligibilityCriteria":111,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":112,"enrollmentInfo":113,"targetDuration":4,"studyType":52,"phases":115,"briefSummary":116,"conditions":117,"keywords":123,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":132,"lastUpdatePostDateStruct":133,"startDateStruct":135,"completionDateStruct":137,"leadSponsor":139,"locationsCount":41},"100480030","correlation-pelvic-floor-function-and-ultrasound-findings-one-year-after-childbirth-100480030","NCT05530681","Correlation Pelvic Floor Function and Ultrasound Findings One Year After Childbirth","DeliverUU","Inclusion Criteria:\n\n* age = or \\> 18 years\n* Dutch\u002FEnglish-speaking\n* \\> 33 weeks gestation\n* delivering in UZ Leuven\n* vaginal delivery\n\nExclusion Criteria:\n\n* age \\\u003C 18 years\n* not Dutch\u002FEnglish-speaking\n* \\\u003C 33 weeks gestation\n* not delivering in UZ Leuven\n* non-vaginal delivery\n* Any disorder, that independently from delivery, affects pelvic floor function or structure, such as, but not limited to musculoskeletal or neurologic diseases.\n* any women with drug addiction, cognitive deficit, language-barrier and illiteracy\n* any disorder or timing or circumstances, which in the Investigator's opinion represents an obstacle to proper informed consent, or safe and\u002For compliant participation.\n* any prior or simultaneous treatment(s) potentially jeopardising safety or compromising trial integrity.","45 Years",{"count":114,"type":21},320,[54],"This is a single-center prospective cohort study sponsored by the University Hospitals Leuven (UZ). Women will undergo a pelvic floor ultrasound and will be asked to fill out a questionnaire at the time of their admission into the labour suite, at the postpartum check-up and 12 months postpartum.\n\nThe primary objective is to correlate self-reported symptoms of Pelvic Floor Dysfunction (PFD) (binary outcome) at one year after delivery with structural changes to the Pelvic Floor Muscles (PFM) and postpartum evidence of levator avulsion (binary indicator) as measured by TransPerineal UltraSound (TPUS).\n\nSecondary objectives are to compare demographical and obstetrical variables between patients suffering from PFD symptoms or pelvic floor injury (documented one year after delivery) and those who do not; to record how patients manage and cope with PFD including recovery and compliance with Pelvic Floor Muscle Training (PFMT) as prescribed in the standard pathway of peripartum care; and to use of TPUS images for the development of artificial intelligence tools for automated image analysis.\n\nPrimary outcomes are PFD symptoms one year after delivery and injury to the PFM evidenced by POP-Q and TPUS. The demographic variables and information about the pregnancy and the delivery will be obtained from the medical records.\n\nThe presence and severity of PFD will be measured using standardized self-reporting tools: Pelvic Organ Prolapse Distress Index (POP-DI), Patient Assessment Constipation-SYMptoms (PAC-SYM), International Consultation on Incontinence Questionnaire - Urinary Incontinence - Short Form (ICIQ-SF), St. Mark's Incontinence Score (SMIS), Female Sexual Function Index (FSFI), Female Sexual Distress Scale - Revised (FSDS-R). FSFI is a widely used generic tool with sufficient granularity and validated in a large number of languages. FSDS-R assesses the construct \"personal distress\", which has been considered as an additional important aspect contributing to sexual dysfunction of women.\n\nPFD, as a clustered outcome, being the presence of any kind of pelvic floor dysfunction symptoms, will be defined as POP-DI score of ≥11 OR ICIQ-SF score of ≥1 OR SMIS score of ≥1 OR FSFI score ≤ 26.55 OR FSDS-R score ≥11.",[118,119,58,25,59,120,60,121,122],"Pelvic Floor Disorders","Obstetric Trauma","Pelvic Pain","Constipation","Anal Sphincter Injury",[124,125,126,127,128,129,130,131],"urinary incontinence","anal incontinence","pelvic organ prolapse","sexual dysfunction","constipation","postpartum","levator avulsion","anal sphincter injury","2024-06-28",{"date":134,"type":33},"2024-07-01",{"date":136,"type":33},"2022-08-17",{"date":138,"type":21},"2025-09-01",{"name":140,"class":40},"Universitaire Ziekenhuizen KU Leuven",{"id":142,"slug":143,"hasResults":11,"nctId":144,"briefTitle":145,"officialTitle":146,"acronym":4,"eligibilityCriteria":147,"healthyVolunteers":49,"sex":17,"minAge":18,"maxAge":78,"enrollmentInfo":148,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":150,"conditions":151,"keywords":152,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":156,"lastUpdatePostDateStruct":157,"startDateStruct":159,"completionDateStruct":161,"leadSponsor":163,"locationsCount":41},"100548609","anal-incontinence-and-its-impact-on-quality-of-life-and-physical-activity-among-hungarian-women-and-the-hungarian-language-validation-of-the-international-consultation-on-incontinence-modular-questionnaire-bowels-iciq-b-100548609","NCT06423222","Anal Incontinence and Its Impact on Quality of Life and Physical Activity Among Hungarian Women and the Hungarian Language Validation of the International Consultation on Incontinence Modular Questionnaire-Bowels (ICIQ-B)","Prevalence of Anal Incontinence and Its Impact on Quality of Life and Physical Activity Among Hungarian Women Who Have Given Birth, and the Hungarian Language Validation of the International Consultation on Incontinence Modular Questionnaire-Bowels (ICIQ-B)","Inclusion Criteria:\n\n* Have given birth at least once before\n* Native Hungarian language\n\nExclusion Criteria:\n\n* Menopause\n* Irritable Bowel Syndrome (IBS)\n* Chron's disease\n* Ulcerative colitis\n* Developmental abnormalities at the level of the pelvic organs\n* Uninvestigated pelvic pain\n* Malignant pelvic tumor\n* Radiotherapy involving the pelvis\n* Neurological diseases with muscle weakness\n* Parkinson's disease\n* Intellectual disability",{"count":149,"type":21},250,"The aim of the study is to assess the prevalence of anal incontinence among Hungarian women who have given birth at least once before, and to examine the impact of anal incontinence on the quality of life and physical activity of these women. A further aim of our study is to adapt the Hungarian version of the International Consultation on Incontinence Modular Questionnaire - Bowels (ICIQ-B) and to assess its validity and reliability.",[25],[25,153,154,155],"Quality of Life","Physical Activity","Questionnaire","2024-05-15",{"date":158,"type":33},"2024-05-21",{"date":160,"type":33},"2024-04-22",{"date":162,"type":21},"2027-07",{"name":164,"class":40},"University of Pecs"]