[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"analgesia-postoperative\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:analgesia-postoperative":54},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,9,0,[8,39,71,102,131,161,182,209,236],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":29,"startDateStruct":32,"completionDateStruct":33,"leadSponsor":35,"locationsCount":38},"100618228","phase-4-effect-of-single-dose-intravenous-magnesium-sulfate-on-postoperative-analgesic-consumption-in-patients-undergoing-laparoscopic-cholecystectomy-100618228",false,"NCT07328893","Effect of Single Dose Intravenous Magnesium Sulfate on Postoperative Analgesic Consumption in Patients Undergoing Laparoscopic Cholecystectomy","Inclusion Criteria:\n\nAge - 18 - 65 years, either sex American Society of Anesthesiologists (ASA) Physical status classification system group I and II Elective laparoscopic cholecystectomy\n\nExclusion Criteria:\n\nPatient refusal BMI \\> 30 kg\u002Fm² OSA Renal, hepatic or cardiovascular dysfunction including cardiac conduction disorders Those on long term calcium channel blockers or receiving magnesium supplements Opioid or analgesic abuse Psychiatric illness Surgical duration \\\u003C 1 h \\& \\> 3 h Lap converted to open","ALL","18 Years","65 Years",{"count":19,"type":20},106,"ESTIMATED","INTERVENTIONAL",[23],"PHASE4","This study describes a randomized controlled trial designed to evaluate the impact of a single intravenous dose of magnesium sulfate on postoperative analgesic consumption in patients undergoing laparoscopic cholecystectomy. The primary aim is to determine if magnesium sulfate can reduce postoperative morphine usage and its associated side effects.\n\nThe study will involve 106 patients (53 per arm), aged 18-65, classified as ASA physical status I or II, who are scheduled for elective laparoscopic cholecystectomy. Participants will be randomly assigned to receive either 30 mg\u002Fkg intravenous magnesium sulfate or a placebo (normal saline), alongside standard anesthetic care. Secondary outcomes include pain scores, the time until rescue analgesia is needed, and the monitoring of hemodynamic responses and potential adverse events. Statistical analysis will utilize descriptive statistics, chi-square tests, and t-tests or Mann-Whitney U-tests to compare the two groups.",[26],"Analgesia; Postoperative","RECRUITING","2025-12-27",{"date":30,"type":31},"2026-01-09","ACTUAL",{"date":28,"type":20},{"date":34,"type":20},"2026-12-31",{"name":36,"class":37},"Tata Main Hospital","OTHER",2,{"id":40,"slug":41,"hasResults":11,"nctId":42,"briefTitle":43,"officialTitle":44,"acronym":4,"eligibilityCriteria":45,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":46,"enrollmentInfo":47,"targetDuration":4,"studyType":21,"phases":49,"briefSummary":50,"conditions":51,"keywords":56,"overallStatus":60,"whyStopped":4,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":70},"100572751","phase-4-bupivacaine-liposomes-or-bupivacaine-for-cmb-on-postoperative-analgesia-in-laparoscopic-hepatobiliary-pancreatic-surgery-100572751","NCT06737341","Bupivacaine Liposomes or Bupivacaine for CMB on Postoperative Analgesia in Laparoscopic Hepatobiliary Pancreatic Surgery","Effect of Bupivacaine Liposomes or Bupivacaine for Ultrasound-guided CMB on Postoperative Analgesia in Laparoscopic Hepatobiliary Pancreatic Surgery: a Prospective, Single Blind, Completely Randomized, Active Controlled Clinical Trial","Inclusion Criteria:\n\n* 18-80 years old ASA Level I-III Laparoscopic Hepatobiliary Pancreatic Surgery\n\nExclusion Criteria:\n\n* Body Mass Index (BMI) ≥ 30 kg\u002Fm ² or ≤ 15 kg\u002Fm ² Known alcohol or drug abuse History of upper abdominal surgery Congenital coagulation dysfunction Localized or systemic infection Peripheral neuropathy Unable to understand the research plan","80 Years",{"count":48,"type":20},60,[23],"Numerous studies have confirmed that regional analgesia using peripheral nerve block has great potential for perioperative analgesia in abdominal surgery. Ultrasound guided costal margin block (CMB) is a new regional anesthesia technique that has been proven to compensate for the analgesic effects of regional analgesia techniques such as transverse abdominal muscle plane (TAP) and rectus abdominis sheath (RSB) on mid abdominal incisions, but it is difficult to meet the analgesic needs of anterior and outer abdominal wall incisions. According to relevant anatomy and research, the application of local anesthetics along the rib margin under the rectus abdominis muscle or under the external oblique muscle on the rib surface can block the lateral and anterior cutaneous branches of the thoracoabdominal nerve, known as CMB. Ultrasound guided CMB requires the injection of local anesthetics onto the surface of the rib along the plane below the rectus abdominis and oblique muscles, covering most of the upper abdominal incision pain. However, there are few reports on other types of upper abdominal surgeries such as liver, gallbladder, and pancreas surgeries.\n\nBupivacaine liposomes are an important innovation, which encapsulate bupivacaine in polycystic liposomes using DepoFoam technology to achieve slow drug release and effectively prolong pain relief time by up to 72 hours. This ultra long acting local anesthetic has significant advantages in reducing opioid use, improving analgesic satisfaction, reducing complications, and shortening hospital stays, and has been applied in the ERAS concept.\n\nThe investigators designed a prospective, single blind, randomized, active controlled clinical trial to investigate the effect of bupivacaine liposomes in combination with bupivacaine mixture or bupivacaine alone for ultrasound-guided bilateral CMB on postoperative analgesia in patients undergoing laparoscopic hepatobiliary pancreatic surgery. Our main hypothesis is that the use of bupivacaine liposomes and a mixture of bupivacaine for ultrasound-guided CMB in a multimodal analgesia regimen can more effectively reduce the dosage of intravenous patient-controlled analgesia (PCA) opiates within 72 hours after laparoscopic hepatobiliary pancreatic surgery compared to using bupivacaine alone. Secondary outcomes include the dosage of PCA opiates within 24-48 hours, pain score values, patient satisfaction, adverse reactions, and complications.",[52,53,54,55],"Bupivacaine","Ultrasound-Guided","Analgesia, Postoperative","Opioids",[57,58,59],"Bupivacaine Liposome","Costal Margin Block","Laparoscopic Hepatobiliary Pancreatic Surgery","NOT_YET_RECRUITING","2025-09-30",{"date":63,"type":31},"2025-10-03",{"date":65,"type":20},"2025-10-08",{"date":67,"type":20},"2026-02-01",{"name":69,"class":37},"Huazhong University of Science and Technology",1,{"id":72,"slug":73,"hasResults":11,"nctId":74,"briefTitle":75,"officialTitle":76,"acronym":77,"eligibilityCriteria":78,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":79,"targetDuration":4,"studyType":21,"phases":81,"briefSummary":83,"conditions":84,"keywords":89,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":70},"100585667","guiding-opioid-administration-by-nociception-level-index-nol-in-patients-with-regional-anesthesia-100585667","NCT06905340","Guiding Opioid Administration by Nociception Level Index (NOL) in Patients With Regional Anesthesia","Nociception Level Index-Guided Intraoperative Opioids in Patients With a Combination of General and Regional Anesthesia","NORA","Inclusion Criteria:\n\n\\- Patients undergoing elective trauma or orthopedic surgery with a combination of general and regional anesthesia\n\nExclusion Criteria:\n\n* Preexisting therapy with cardiac glycosides or pacemakers\n* Cardiac arrhythmia (atrial fibrillation, atrioventricular block \\> I°)\n* Chronic opioid misuse\n* Intraoperative treatment with ketamine, beta-adrenergic agonists, or clonidine\n* Serious peripheral or cardiac autonomic neuropathy\n* Inability to specify the postoperative pain level\n* Postoperative treatment in an ICU",{"count":80,"type":20},240,[82],"NA","General anesthesia consists of a combination of hypnotic drugs to achieve unconsciousness and opioid analgesics to ensure antinociception. An alternative approach to the intraoperative administration of high-potency opioids to achieve antinociception during surgery is combining general anesthesia with regional anesthesia. Modern general anesthesia aims to avoid an overdose of opioid analgesics and reduce side effects of opioid administration. Quality and safety of general anesthesia are of major clinical importance and can be improved by adjusting the opioid analgesics to the optimal individual dose needed.\n\nIn current clinical practice, opioid dosage is usually determined by clinical judgment. However, different monitoring devices estimating the effect of nociception during unconsciousness have become commercially available. One of the most recent commercially available nociception indices is the Nociception Level Index (NOL). Until today, there is conflicting evidence on whether guiding sufentanil administration by NOL monitoring, which is the intended use of the nociception index, affects postoperative pain level in the postanesthesia care unit (PACU), the amount of postoperatively administered opioids, and the quality of postoperative recovery in patients with a combination of general and regional anesthesia. This study aims to investigate the clinical performance of intraoperative NOL monitoring and determine whether guiding sufentanil administration by NOL monitoring - compared to routine care - reduces either postoperative pain level in the PACU, postoperative opioid consumption in the PACU or postoperative opioid consumption in the first 24 hours after the operation in patients having trauma and orthopedic surgery with combined general and regional anesthesia.",[85,86,54,87,88],"Nociceptive Pain","Pain, Postoperative","Anesthesia Recovery Period","Opioid Use",[90,91,92,55],"General anesthesia","Regional anesthesia","Analgesia Monitoring","2025-06-04",{"date":95,"type":31},"2025-06-08",{"date":97,"type":31},"2025-05-12",{"date":99,"type":20},"2026-01",{"name":101,"class":37},"Universitätsklinikum Hamburg-Eppendorf",{"id":103,"slug":104,"hasResults":11,"nctId":105,"briefTitle":106,"officialTitle":107,"acronym":4,"eligibilityCriteria":108,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":46,"enrollmentInfo":109,"targetDuration":4,"studyType":21,"phases":111,"briefSummary":112,"conditions":113,"keywords":116,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":122,"lastUpdatePostDateStruct":123,"startDateStruct":125,"completionDateStruct":127,"leadSponsor":129,"locationsCount":70},"100588001","phase-4-intrathecal-morphine-versus-epidural-analgesia-for-open-colon-surgery-100588001","NCT06935708","Intrathecal Morphine Versus Epidural Analgesia for Open Colon Surgery","Intrathecal Morphine Versus Thoracic Epidural Analgesia for Open Colorectal Cancer Surgery: a Randomized Controlled Trial","Inclusion Criteria:\n\n* Male or female patients with colorectal carcinoma undergoing laparoscopic abdominal surgery aged 18-80 years, ASA classification I-III, Body Mass Index (BMI) 15-35 kg\u002Fm2.\n\nExclusion Criteria:\n\n* abnormal coagulation function, defined as prothrombin time or activated partial prothrombin time above standard laboratory values or an international normalised ratio (INR) ≥1.4; or receiving ongoing therapeutic anticoagulation,\n* thrombocytopenia, defined as a platelet count \\\u003C80×10 9 L-1,\n* pre-existing skin infection at the neuraxial anesthesia puncture site,\n* pre-existing neurologic deficit, including peripheral neuropathy,\n* patients with dementia or other medical condition that includes communication difficulties,\n* patients with bradycardia (pulse \\\u003C50\u002Fmin) or with conduction block (2nd or 3rd degree)\n* history of opioid abuse,\n* allergies to any of the drugs used in the study.\n\nAdditionally, patients converted from laparoscopy to laparotomy due to technical surgical issues, patients with postoperative surgical complications (need for revision) or if epidural catheter placement\u002Fspinal anesthesia is unsuccessful even after an attempt by a senior anesthesiologist will also be excluded.",{"count":110,"type":20},98,[23],"Effective pain management after abdominal surgery is essential for recovery. This study compares two pain relief methods-intrathecal morphine (a single spinal injection) and continuous epidural analgesia-for patients undergoing open colorectal cancer surgery.\n\nThe investigators expect intrathecal morphine to provide equal pain relief at rest 24 hours after surgery, while epidural analgesia may be more effective during movement. By 48 to 72 hours, both methods should offer similar pain control. The epidural group may require fewer additional pain medications but could experience more side effects, including a higher risk of low blood pressure and technical difficulties. Additionally, these patients may have a slightly longer hospital stay. In contrast, the intrathecal morphine group may have fewer overall side effects. Despite these differences, patient satisfaction, sleep quality, and recovery are expected to be similar in both groups.\n\nBy evaluating these methods, this study aims to determine the most effective and safe approach to post-surgical pain management, improving comfort and recovery outcomes for patients.",[114,54,115],"Colorectal Carcinoma","Laparotomy",[117,118,119,120,121],"postoperative pain","analgesia","epidural","intrathecal morphine","laparotomy","2025-04-18",{"date":124,"type":31},"2025-04-20",{"date":126,"type":31},"2025-04-08",{"date":128,"type":20},"2026-11",{"name":130,"class":37},"Meri Mirceta",{"id":132,"slug":133,"hasResults":11,"nctId":134,"briefTitle":135,"officialTitle":136,"acronym":4,"eligibilityCriteria":137,"healthyVolunteers":138,"sex":15,"minAge":139,"maxAge":140,"enrollmentInfo":141,"targetDuration":4,"studyType":21,"phases":143,"briefSummary":144,"conditions":145,"keywords":146,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":151,"lastUpdatePostDateStruct":152,"startDateStruct":154,"completionDateStruct":156,"leadSponsor":158,"locationsCount":70},"100574425","comparison-between-fentanyl-and-dexmedetomidine-as-adjuvant-to-bupivacaine-in-combined-ipack-and-adductor-canal-block-for-postoperative-analgesia-after-knee-surgeries-100574425","NCT06759116","Comparison Between Fentanyl and Dexmedetomidine As Adjuvant to Bupivacaine in Combined IPACK and Adductor Canal Block for Postoperative Analgesia After Knee Surgeries","Analgesic Effect of Fentanyl Vs Dexmedetomidine As Adjuvant to Bupivacaine in Combined IPACK and Adductor Canal Block After Knee Surgeries","Inclusion Criteria:\n\n1 - Patient acceptance 2. Cooperative patients 3. Age: ≥21 and 85\\\u003C years' old 4. Sex: both sexes (males or females). 5. Physical status: ASA Ι \\& II\\& Ш. 6. Body Mass Index (BMI): ≤ 35 kg\u002Fm2. 7. Type of operation: elective unilateral knee surgeries (TKA, ACL, knee arthroscopy)\n\nExclusion Criteria:\n\n. Patient with any contraindications of regional blocks (as coagulopathy or local infection at injection site) 2. Patients with known history of allergy to the study drugs (bupivacaine, dexmedetomidine and fentanyl).\n\n3\\. Advanced hepatic, renal, cardiovascular, neurologic and respiratory diseases.\n\n4.Chronic opioid use (more than 3 months or daily oral morphine \\> 5 mg \u002Fday for 1 month)\n\n\\-",true,"21 Years","85 Years",{"count":142,"type":20},111,[82],"This study will be undertaken to compare the analgesic effects of of fentanyl versus dexmedetomidine as adjuvant to bupivacaine in combined IPACK and ACB for pain management after total knee arthroplasty.",[54],[147,148,118,149,150],"fentanyl","dexamedetomidine","IPACK and adductor canal block","knee surgeries","2025-01-12",{"date":153,"type":31},"2025-01-14",{"date":155,"type":31},"2025-01-10",{"date":157,"type":20},"2025-08-10",{"name":159,"class":160},"Zagazig University","OTHER_GOV",{"id":162,"slug":163,"hasResults":11,"nctId":164,"briefTitle":165,"officialTitle":165,"acronym":4,"eligibilityCriteria":166,"healthyVolunteers":138,"sex":15,"minAge":16,"maxAge":167,"enrollmentInfo":168,"targetDuration":4,"studyType":21,"phases":170,"briefSummary":171,"conditions":172,"keywords":4,"overallStatus":60,"whyStopped":4,"lastUpdateSubmitDate":173,"lastUpdatePostDateStruct":174,"startDateStruct":176,"completionDateStruct":178,"leadSponsor":180,"locationsCount":70},"100575679","comparison-between-ultrasound-guided-erector-spinae-plane-block-and-dexmedotomidine-in-lumber-spine-surgeries-100575679","NCT06775418","Comparison Between Ultrasound Guided Erector Spinae Plane Block and Dexmedotomidine in Lumber Spine Surgeries.","Inclusion Criteria:\n\n* ASA I and II patients. aged 18 to 50 years. 70 to 80 kg.\n\nExclusion Criteria:\n\n* patients under 18 years of age.\n\n  * History of Allergic reactions to study drugs.\n  * Opioid or analgesic abuse, and chronic treatment with opioids, or nonsteroidal anti-inflammatory drugs.\n  * History of bleeding tendency or coagulopathy","50 Years",{"count":169,"type":20},30,[82],"Ultrasound (US) guided Erector spinae plane block (ESPB) as a new trunchal fascial plane block technique was proposed in 2016. US guided ESPB has aroused the interest of many nerve block experts. The goal of this study is to evaluate the effect of US guided ESPB versus (VS) intravenous Dexmedotomidine on postoperative analgesia and intra operative hemodynamic parameters in lumbar spine surgeries.\n\nThe aim of this study is to compare the efficacy of ESPB to intravenous Dexmedetomidine in patients who are undergoing elective lumber spine surgeries regarding the effect on postoperative analgesia and intra operative hemodynamic parameters.",[54],"2025-01-09",{"date":175,"type":31},"2025-01-15",{"date":177,"type":20},"2025-01",{"date":179,"type":20},"2025-04",{"name":181,"class":37},"Ain Shams University",{"id":183,"slug":184,"hasResults":11,"nctId":185,"briefTitle":186,"officialTitle":187,"acronym":4,"eligibilityCriteria":188,"healthyVolunteers":138,"sex":15,"minAge":189,"maxAge":190,"enrollmentInfo":191,"targetDuration":4,"studyType":21,"phases":193,"briefSummary":194,"conditions":195,"keywords":196,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":201,"lastUpdatePostDateStruct":202,"startDateStruct":204,"completionDateStruct":206,"leadSponsor":208,"locationsCount":38},"100573897","ultrasound-guided-paravertebral-block-versus-erector-spinae-block-for-postoperative-analgesia-after-inguinal-hernia-repair-in-pediatric-patients-100573897","NCT06752252","Ultrasound Guided Paravertebral Block Versus Erector Spinae Block for Postoperative Analgesia After Inguinal Hernia Repair in Pediatric Patients","Ultrasound Guided Paravertebral Block Versus Erector Spinae Plane Block for Postoperative Analgesia After Inguinal Hernia Repair in Pediatric Patients: a Randomized Clinical Trial","Inclusion Criteria:\n\n1 - Parents acceptance\n\n2\\. Age: preschool and school age child (24 months-12 years old).\n\n3\\. Sex: both sex (males or females).\n\n4\\. Physical status: ASA 1\\& II.\n\n5\\. Type of operation: elective unilateral inguinal hernia repair\n\nExclusion Criteria:\n\n1- Patient with any contraindications of regional blocks (as coagulopathy or local infection at injection site)\n\n2\\. Patients with known history of allergy to the study drugs (bupivacaine and lidocaine).\n\n3\\. Advanced hepatic, renal, cardiovascular, neurologic and respiratory diseases.","24 Months","12 Years",{"count":192,"type":20},158,[82],"The aim of the study is to compare postoperative analgesia in pediatric patients undergoing inguinal hernia repair by comparing the efficacy of ultrasound guided paravertebral block versus ultrasound guided erector spinae plane block.",[54],[197,198,199,200],"postoperative analgesia","ultrasound guided paravertebral block","ultrasound guided erector spinae plane block","inguinal hernia repair in pediatric","2024-12-31",{"date":203,"type":31},"2025-01-01",{"date":205,"type":31},"2024-12-30",{"date":207,"type":20},"2025-12-30",{"name":159,"class":160},{"id":210,"slug":211,"hasResults":11,"nctId":212,"briefTitle":213,"officialTitle":213,"acronym":214,"eligibilityCriteria":215,"healthyVolunteers":11,"sex":15,"minAge":216,"maxAge":217,"enrollmentInfo":218,"targetDuration":4,"studyType":21,"phases":220,"briefSummary":221,"conditions":222,"keywords":224,"overallStatus":60,"whyStopped":4,"lastUpdateSubmitDate":227,"lastUpdatePostDateStruct":228,"startDateStruct":230,"completionDateStruct":232,"leadSponsor":234,"locationsCount":70},"100567197","evaluating-the-analgesic-efficacy-of-oxycodone-hydrochloride-in-pediatric-laparoscopic-cryptorchidism-surgery-100567197","NCT06665048","Evaluating the Analgesic Efficacy of Oxycodone Hydrochloride in Pediatric Laparoscopic Cryptorchidism Surgery","Anesthesia","Inclusion Criteria:\n\n* Age range: patients between 1 and 6 years old who are scheduled to undergo cryptorchid surgery.\n* No severe cardiopulmonary dysfunction, able to tolerate endotracheal intubation and general anesthesia.\n* Children who have not received long-term analgesic medication before surgery.\n* Children with a BMI range of 18.5-24 kg\u002Fm2.\n\nExclusion Criteria:\n\n* History of allergy to oxycodone hydrochloride, fentanyl or other research-related drugs.\n* Children who have severe pain or need long-term analgesic treatment.\n* Combined with other serious diseases, such as malignant tumors, nervous system diseases, severe infections, coagulation disorders, congenital heart disease or other congenital malformations, and any other diseases that may interfere with the results of the study.\n* Children who have received medication that may affect the evaluation of analgesic effects (such as other analgesics, sedatives, antidepressants, etc.) within two weeks before surgery.\n* There are other situations that are not suitable for participation in this study, such as the child or family members cannot cooperate to complete the research requirements and may not be able to keep in touch during the study.","1 Year","6 Years",{"count":219,"type":20},162,[82],"Cryptorchidism surgery is a common pediatric procedure, often performed laparoscopically to reposition undescended testes into the scrotum. This technique involves manipulation and traction of the spermatic cord, which can lead to emergence agitation and short-term postoperative pain. Managing these symptoms effectively is essential for enhancing perioperative comfort and supporting faster recovery in children.\n\nOxycodone hydrochloride, a newer opioid with established analgesic effects in adult surgery, has been less studied in pediatric contexts. This randomized controlled trial aims to evaluate the effects of administering 0.1 mg\u002Fkg oxycodone hydrochloride 30 minutes before the end of laparoscopic cryptorchidism surgery in children aged 1 to 6. The study will assess outcomes such as anesthesia emergence time, extubation time, incidence of emergence agitation, postoperative analgesia, and nausea and vomiting. The goal is to determine if oxycodone hydrochloride could be an effective choice for pain relief in pediatric laparoscopic surgery, potentially reducing pain and complications, and providing clinical evidence to optimize anesthesia management for safer and more satisfactory pediatric surgical care.\n\nThis research aspires to contribute to the guidelines for pediatric anesthesia, offering a scientific basis for the clinical application of oxycodone hydrochloride in children.",[214,223,54],"Oxycodone",[225,223,226],"anesthesia","Analgesia, postoperative","2024-10-28",{"date":229,"type":31},"2024-10-30",{"date":231,"type":20},"2024-12-01",{"date":233,"type":20},"2026-06-01",{"name":235,"class":37},"Shantou University Medical College",{"id":237,"slug":238,"hasResults":11,"nctId":239,"briefTitle":240,"officialTitle":240,"acronym":4,"eligibilityCriteria":241,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":242,"targetDuration":4,"studyType":21,"phases":244,"briefSummary":246,"conditions":247,"keywords":4,"overallStatus":60,"whyStopped":4,"lastUpdateSubmitDate":248,"lastUpdatePostDateStruct":249,"startDateStruct":251,"completionDateStruct":253,"leadSponsor":255,"locationsCount":4},"100566687","phase-1-erector-spinae-plane-block-with-dexmedetomidine-and-bupivacain-versus-dexamethasone-and-bupivacain-for-postoperative-analgesia-in-patients-undergoing-abdominal-surgeries-100566687","NCT06658418","Erector Spinae Plane Block with Dexmedetomidine and Bupivacain Versus Dexamethasone and Bupivacain for Postoperative Analgesia in Patients Undergoing Abdominal Surgeries","Inclusion Criteria:\n\nAge :18 years old and older. Patients undergoing open abdominal surgery.\n\nExclusion Criteria:\n\n1. Patient refusal\n2. known sensitivity or contraindication to any of study drugs\n3. contraindications for local anesthesia\n4. Patients with local infection at site of puncture\n5. uncooperative patients\n6. history of psychological disorders or chronic pain and significant liver or renal disease.",{"count":243,"type":20},90,[245],"PHASE1","To compare the analgesic effect of dexmedetomidine combined with bupivacaine versus dexamethasone combined with bupivacaine for ultrasound-guided ESPB for postoperative pain control in patients scheduled for abdominal surgeries",[54],"2024-10-24",{"date":250,"type":31},"2024-10-26",{"date":252,"type":20},"2024-11-01",{"date":254,"type":20},"2026-12-01",{"name":256,"class":37},"Loay Gamal"]